Molecular Fluorescent Sensors for Cellular Studies
Molecular Fluorescent Sensors for Cellular Studies

Author: Elizabeth J. New

Publisher: John Wiley & Sons

Published: 2022-08-16

Total Pages: 308

ISBN-13: 1119749867

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Molecular Fluorescent Sensors for Cellular Studies Enables readers to fully understand the fundamentals and chemical principles of fluorescent sensing and the design of fluorescent sensors Fluorescent sensors are able to provide specific chemical information about cells and can be invaluable in understanding processes that underpin health and disease. Molecular Fluorescent Sensors for Cellular Studies provides an avenue into and overview of currently available fluorescent sensing technology and its application to biological imaging. This book aims to help the reader understand the principles of fluorescence and the mechanisms by which fluorescent sensors operate in order to ensure appropriate and optimal use of sensors. Key applications of fluorescent sensing are presented, with explanations not only of how new sensors can be designed, but also how existing sensors can be applied to various biological settings and conditions. Clear and engaging schematics throughout the book explain chemical principles of sensing to the non-expert. Discusses the breadth of fluorescent sensors, from commercially available sensors to those reported in literature which are yet to be used widely Explains how fluorescent sensors operate for appropriate and optimal use from a theoretical standpoint Provides guidance on how to achieve optimal use of fluorescent sensors in practical settings Summarizes the principles behind fluorescent sensors and their design This work will be an invaluable resource for postgraduates and professionals in the fields of microscopy, bioimaging, and diagnostic imaging who wish to harness the information to improve practical applications and to gain key knowledge surrounding the many facets of fluorescent sensing. It is also of interest to medical and biological researchers working across industry, universities and medical institutes.

Molecular Fluorescent Sensors for Cellular Studies
Molecular Fluorescent Sensors for Cellular Studies

Author: Elizabeth J. New

Publisher: John Wiley & Sons

Published: 2022-08-15

Total Pages: 308

ISBN-13: 1119749816

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Molecular Fluorescent Sensors for Cellular Studies Enables readers to fully understand the fundamentals and chemical principles of fluorescent sensing and the design of fluorescent sensors Fluorescent sensors are able to provide specific chemical information about cells and can be invaluable in understanding processes that underpin health and disease. Molecular Fluorescent Sensors for Cellular Studies provides an avenue into and overview of currently available fluorescent sensing technology and its application to biological imaging. This book aims to help the reader understand the principles of fluorescence and the mechanisms by which fluorescent sensors operate in order to ensure appropriate and optimal use of sensors. Key applications of fluorescent sensing are presented, with explanations not only of how new sensors can be designed, but also how existing sensors can be applied to various biological settings and conditions. Clear and engaging schematics throughout the book explain chemical principles of sensing to the non-expert. Discusses the breadth of fluorescent sensors, from commercially available sensors to those reported in literature which are yet to be used widely Explains how fluorescent sensors operate for appropriate and optimal use from a theoretical standpoint Provides guidance on how to achieve optimal use of fluorescent sensors in practical settings Summarizes the principles behind fluorescent sensors and their design This work will be an invaluable resource for postgraduates and professionals in the fields of microscopy, bioimaging, and diagnostic imaging who wish to harness the information to improve practical applications and to gain key knowledge surrounding the many facets of fluorescent sensing. It is also of interest to medical and biological researchers working across industry, universities and medical institutes.

Introduction to Fluorescence Sensing
Introduction to Fluorescence Sensing

Author: Alexander P. Demchenko

Publisher: Springer

Published: 2015-10-06

Total Pages: 818

ISBN-13: 3319207806

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Fluorescence is the most popular technique in chemical and biological sensing and this book provides systematic knowledge of basic principles in the design of fluorescence sensing and imaging techniques together with critical analysis of recent developments. Its ultimate sensitivity, high temporal and spatial resolution and versatility enables high resolution imaging within living cells. It develops rapidly in the directions of constructing new molecular recognition units, new fluorescence reporters and in improving sensitivity of response, up to the detection of single molecules. Its application areas range from the control of industrial processes to environmental monitoring and clinical diagnostics. Being a guide for students and young researchers, it also addresses professionals involved in basic and applied research. Making a strong link between education, research and product development, this book discusses prospects for future progress.

Fluorescent Chemosensors for Ion and Molecule Recognition
Fluorescent Chemosensors for Ion and Molecule Recognition

Author: Anthony W. Czarnik

Publisher:

Published: 1993

Total Pages: 256

ISBN-13:

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From an August 1992 symposium in Washington, D.C., 13 papers report on research into developing fluorescent chemosensors for devices to monitor several critical parameters of blood composition in real time. They aim at opening communication between the clinicians and researchers who want such devices and the scientists and engineers who could develop them. Among the topics are the synthesis and study of crown ethers with alkali- metal-enhanced fluorescence, the tunable florescence of some macrocyclic anthracenophanes, and fluorescent probes in studies of proteases. Annotation copyright by Book News, Inc., Portland, OR

Metal Nanoclusters in Catalysis and Materials Science: The Issue of Size Control
Metal Nanoclusters in Catalysis and Materials Science: The Issue of Size Control

Author: Benedetto Corain

Publisher: Elsevier

Published: 2011-08-11

Total Pages: 471

ISBN-13: 0080555004

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Metal Nanoclusters in Catalysis and Materials Science: The Issue of Size Control deals with the synthesis of metal nanoclusters along all known methodologies. Physical and chemical properties of metal nanoclusters relevant to their applications in chemical processing and materials science are covered thoroughly. Special attention is given to the role of metal nanoclusters size and shape in catalytic processes and catalytic applications relevant to industrial chemical processing.An excellent text for expanding the knowledge on the chemistry and physics of metal nanoclusters. Divided in two parts; Part I deals with general aspects of the matter and Part II has to be considered a useful handbook dealing with the production of metal nanoclusters, especially from their size-control point of view.* Divided into two parts for ease of reference: general and operational * Separation of synthetic aspects, physical properties and applications* Specific attention is given to the task of metal nanoclusters size-control

The Molecular Probes Handbook
The Molecular Probes Handbook

Author: Iain Johnson

Publisher:

Published: 2010

Total Pages: 1060

ISBN-13: 9780982927915

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The most complete fluorescent labeling and detection reference available, The Molecular Probes HandbookA Guide to Fluorescent Probes and Labeling Technologies contains over 3,000 technology solutions representing a wide range of biomolecular labeling and detection reagents. The significantly revised 11th Edition features extensive references, reorganized content, and new technical notes and product highlights.

Metals in Cells
Metals in Cells

Author: Valeria Culotta

Publisher: John Wiley & Sons

Published: 2016-03-16

Total Pages: 608

ISBN-13: 1118636864

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Over the last three decades a lot of research on the role of metals in biochemistry and medicine has been done. As a result many structures of biomolecules with metals have been characterized and medicinal chemistry studied the effects of metal containing drugs. This new book (from the EIBC Book Series) covers recent advances made by top researchers in the field of metals in cells [the “metallome”] and include: regulated metal ion uptake and trafficking, sensing of metals within cells and across tissues, and identification of the vast cellular factors designed to orchestrate assembly of metal cofactor sites while minimizing toxic side reactions of metals. In addition, it features aspects of metals in disease, including the role of metals in neuro-degeneration, liver disease, and inflammation, as a way to highlight the detrimental effects of mishandling of metal trafficking and response to "foreign" metals. With the breadth of our recently acquired understanding of metals in cells, a book that features key aspects of cellular handling of inorganic elements is both timely and important. At this point in our understanding, it is worthwhile to step back and take an expansive view of how far our understanding has come, while also highlighting how much we still do not know. The content from this book will publish online, as part of EIBC in December 2013, find out more about the Encyclopedia of Inorganic and Bioinorganic Chemistry, the essential online resource for researchers and students working in all areas of inorganic and bioinorganic chemistry.

Combinatorial Methods for Chemical and Biological Sensors
Combinatorial Methods for Chemical and Biological Sensors

Author: Radislav A. Potyrailo

Publisher: Springer Science & Business Media

Published: 2009-03-21

Total Pages: 495

ISBN-13: 0387737138

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Chemical sensors are in high demand for applications as varied as water pollution detection, medical diagnostics, and battlefield air analysis. Designing the next generation of sensors requires an interdisciplinary approach. The book provides a critical analysis of new opportunities in sensor materials research that have been opened up with the use of combinatorial and high-throughput technologies, with emphasis on experimental techniques. For a view of component selection with a more computational perspective, readers may refer to the complementary volume of Integrated Analytical Systems edited by M. Ryan et al., entitled “Computational Methods for Sensor Material Selection”.

Systematic Exploration of Indolizine-Based Small Fluorescent Molecules
Systematic Exploration of Indolizine-Based Small Fluorescent Molecules

Author: Youngjun Lee

Publisher: Springer

Published: 2018-08-16

Total Pages: 208

ISBN-13: 9811316457

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This thesis describes an in-depth study of an indolizine-based fluorophore, from understanding of its structure-photophysical property relationship to its application as a useful biological reporter. Organic fluorophores have been extensively used in the field of molecular biology owing to their excellent photophysical property, suitable cell permeability, and synthetic flexibility. Understanding of the structure-photophysical property relationship of a given fluorophore often paves the road to the development of valuable molecular probes to visualize and transcribe biological networks. In this thesis, respective chapters deal with molecular design, organic synthesis, structure-property analysis, and quantum-mechanical interpretation of unexplored family of indolizine-based molecules. This systematic exploration has led to rational development of a new microalgae lipid droplet probe, colorful bioorthogonal fluorogenic probes, and a bright mitochondrial probe, working under live cell conditions. Harnessing the optical properties of a given fluorophore has been an important topic for a couple of decades, both in industry and in academia. This thesis provides useful insights for the improvement and development of unique small fluorescent materials, or optical materials.

Intramolecular Charge Transfer
Intramolecular Charge Transfer

Author: Ramprasad Misra

Publisher: John Wiley & Sons

Published: 2018-02-27

Total Pages: 257

ISBN-13: 3527801944

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Bridging the gap between the multitude of advanced research articles and the knowledge newcomers to the field are looking for, this is a timely and comprehensive monograph covering the interdisciplinary topic of intramolecular charge transfer (ICT). The book not only covers the fundamentals and physico-chemical background of the ICT process, but also places a special emphasis on the latest experimental and theoretical studies that have been undertaken to understand this process and discusses key technological applications. After outlining the discovery of ICT molecules, the authors go on to discuss several important substance classes. They present the latest techniques for studying the underlying processes and show the interplay between charge transfer and the surrounding medium. Examples taken from nonlinear optics, viscosity and polarity sensors, and organic electronics testify to the vast range of applications. The result is a unique information source for experimentalists as well as theoreticians, from postgraduate students to researchers.