Mixture Toxicity

Mixture Toxicity

Author: Cornelis A. M. van Gestel

Publisher: CRC Press

Published: 2016-04-19

Total Pages: 312

ISBN-13: 1439830096

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In the last decade and a half, great progress has been made in the development of concepts and models for mixture toxicity, both in human and environmental toxicology. However, due to their different protection goals, developments have often progressed in parallel but with little integration. Arguably the first book to clearly link ecotoxicology an


Marine Anthropogenic Litter

Marine Anthropogenic Litter

Author: Melanie Bergmann

Publisher: Springer

Published: 2015-06-01

Total Pages: 456

ISBN-13: 3319165100

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This book describes how man-made litter, primarily plastic, has spread into the remotest parts of the oceans and covers all aspects of this pollution problem from the impacts on wildlife and human health to socio-economic and political issues. Marine litter is a prime threat to marine wildlife, habitats and food webs worldwide. The book illustrates how advanced technologies from deep-sea research, microbiology and mathematic modelling as well as classic beach litter counts by volunteers contributed to the broad awareness of marine litter as a problem of global significance. The authors summarise more than five decades of marine litter research, which receives growing attention after the recent discovery of great oceanic garbage patches and the ubiquity of microscopic plastic particles in marine organisms and habitats. In 16 chapters, authors from all over the world have created a universal view on the diverse field of marine litter pollution, the biological impacts, dedicated research activities, and the various national and international legislative efforts to combat this environmental problem. They recommend future research directions necessary for a comprehensive understanding of this environmental issue and the development of efficient management strategies. This book addresses scientists, and it provides a solid knowledge base for policy makers, NGOs, and the broader public.


Toxicological Risk Assessment and Multi-System Health Impacts from Exposure

Toxicological Risk Assessment and Multi-System Health Impacts from Exposure

Author: Aristidis M. Tsatsakis

Publisher: Elsevier

Published: 2021-08-01

Total Pages: 686

ISBN-13: 0323853587

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Toxicological Risk Assessment and Multisystem Health Impacts From Exposure highlights the emerging problems of human and environmental health attributable to cumulative and multiple sources of long-term exposure to environmental toxicants. The book describes the cellular, biological, immunological, endocrinologic, genetic, and epigenetic effects of long-term exposure. It examines how the combined exposure to nanomaterials, metals, pharmaceuticals, multifrequency radiation, dietary mycotoxins, and pesticides accelerates ecotoxicity in humans, animals, plants, and the larger environment. The book goes on to also offer insights into mixture risk assessments, protocols for evaluating the risks, and how this information can serve the regulatory agencies in setting safer exposure limits. The book is a go-to resource for scientists and professionals in the field tackling the current and emerging trends in modern toxicology and risk assessment. - Bridges basic research with clinical, epidemiological, regulatory, and translational research, conveying both an introductory understanding and the latest developments in the field - Evaluates real-life human health risk assessment for long-term exposures to xenobiotic mixtures and the role they play in contributing to chronic disease - Discusses advances in predictive (in silico) toxicology tools and the benefits of using omics technologies in toxicology research


Encyclopedia of Aquatic Ecotoxicology

Encyclopedia of Aquatic Ecotoxicology

Author: Jean-Francois Férard

Publisher: Springer

Published: 2013-06-14

Total Pages: 0

ISBN-13: 9789400750401

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With its 104 chapters, this Encyclopedia of aquatic ecotoxicology reveals the diversity of issues, problems and challenges that have faced, and are facing today, receiving environments. It also indicates ways by which tools, strategies and future investigations can contribute to correct, minimize, solve and prevent water quality degradation. Structured homogeneously, the chapters convey salient information on historical background, features, characteristics, uses and/or applications of treated topics, often complemented by illustrations and case studies, as well as by conclusions and prospects. This work is most suitable for teaching purposes. Academics, for example, could literally deliver comprehensive lectures to students simply based on chapter outlines and contents. Meet the Authors of the Encyclopedia! Check out 'Meet the Authors' under ADDITIONAL INFORMATION (Right menu).


How Tobacco Smoke Causes Disease

How Tobacco Smoke Causes Disease

Author: United States. Public Health Service. Office of the Surgeon General

Publisher:

Published: 2010

Total Pages: 728

ISBN-13:

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This report considers the biological and behavioral mechanisms that may underlie the pathogenicity of tobacco smoke. Many Surgeon General's reports have considered research findings on mechanisms in assessing the biological plausibility of associations observed in epidemiologic studies. Mechanisms of disease are important because they may provide plausibility, which is one of the guideline criteria for assessing evidence on causation. This report specifically reviews the evidence on the potential mechanisms by which smoking causes diseases and considers whether a mechanism is likely to be operative in the production of human disease by tobacco smoke. This evidence is relevant to understanding how smoking causes disease, to identifying those who may be particularly susceptible, and to assessing the potential risks of tobacco products.


Contaminated Water Supplies at Camp Lejeune

Contaminated Water Supplies at Camp Lejeune

Author: National Research Council

Publisher: National Academies Press

Published: 2009-09-06

Total Pages: 338

ISBN-13: 0309136997

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In the early 1980s, two water-supply systems on the Marine Corps Base Camp Lejeune in North Carolina were found to be contaminated with the industrial solvents trichloroethylene (TCE) and perchloroethylene (PCE). The water systems were supplied by the Tarawa Terrace and Hadnot Point watertreatment plants, which served enlisted-family housing, barracks for unmarried service personnel, base administrative offices, schools, and recreational areas. The Hadnot Point water system also served the base hospital and an industrial area and supplied water to housing on the Holcomb Boulevard water system (full-time until 1972 and periodically thereafter). This book examines what is known about the contamination of the water supplies at Camp Lejeune and whether the contamination can be linked to any adverse health outcomes in former residents and workers at the base.


A New Paradigm for Environmental Chemistry and Toxicology

A New Paradigm for Environmental Chemistry and Toxicology

Author: Guibin Jiang

Publisher: Springer

Published: 2019-08-09

Total Pages: 274

ISBN-13: 9811394474

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This book provides comprehensive coverage of the theoretical developments and technological breakthroughs that have deepened our understanding of environmental pollution and human health, while also promoting a comprehensive strategy to address these problems. The respective chapters highlight groundbreaking concepts fueling the development of environmental chemistry and toxicology; revolutionary analytical and computational approaches providing novel insights into environmental health; and nature-inspired, innovative engineering solutions for tackling complex hazardous exposures. The book also features a forward-looking perspective on emerging environmental issues that call for new research and regulatory paradigms, laying the groundwork for future advances in the broad field of environmental chemistry and toxicology. Written by respected authorities in the field, A New Paradigm for Environmental Chemistry and Toxicology - From Concepts to Insights will offer an invaluable reference guide for concerned researchers and professional practitioners for years to come.


Public Health Consequences of E-Cigarettes

Public Health Consequences of E-Cigarettes

Author: National Academies of Sciences, Engineering, and Medicine

Publisher: National Academies Press

Published: 2018-05-18

Total Pages: 775

ISBN-13: 030946837X

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Millions of Americans use e-cigarettes. Despite their popularity, little is known about their health effects. Some suggest that e-cigarettes likely confer lower risk compared to combustible tobacco cigarettes, because they do not expose users to toxicants produced through combustion. Proponents of e-cigarette use also tout the potential benefits of e-cigarettes as devices that could help combustible tobacco cigarette smokers to quit and thereby reduce tobacco-related health risks. Others are concerned about the exposure to potentially toxic substances contained in e-cigarette emissions, especially in individuals who have never used tobacco products such as youth and young adults. Given their relatively recent introduction, there has been little time for a scientific body of evidence to develop on the health effects of e-cigarettes. Public Health Consequences of E-Cigarettes reviews and critically assesses the state of the emerging evidence about e-cigarettes and health. This report makes recommendations for the improvement of this research and highlights gaps that are a priority for future research.


Chemical Mixtures and Combined Chemical and Nonchemical Stressors

Chemical Mixtures and Combined Chemical and Nonchemical Stressors

Author: Cynthia V. Rider

Publisher: Springer

Published: 2018-02-16

Total Pages: 554

ISBN-13: 3319562347

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In this book, both basic and advanced concepts are discussed for considering mixtures from initial exposure characterization through evaluation of risk associated with combined exposures. This book will provide an introduction to key issues and multiple options for evaluating both the toxicity of mixtures as well as the risk associated with exposure to mixtures. Additionally, promising tools adapted from other disciplines will be discussed in the context of mixtures toxicology and risk assessment. Finally, the discussion will move beyond chemical mixtures to address incorporating non-chemical stressors into toxicity studies and cumulative risk assessments. Although exposure to multiple chemical and non-chemical stressors is the rule, not the exception, consideration of mixtures in toxicology and risk assessment continues to be a significant challenge. This book will be an essential resource for researchers and professionals in the fields of toxicology, epidemiology, exposure science, risk assessment, and statistics.