Microvascular Research: Biology and Pathology, Two-Volume Set

Microvascular Research: Biology and Pathology, Two-Volume Set

Author: David Shepro

Publisher: Elsevier

Published: 2005-11-03

Total Pages: 1353

ISBN-13: 0126395101

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The microvasculature refers to the smallest blood vessels, arterial and venous, that nurture the tissues of each organ. Apart from transport, they also contribute to the systematic regulation of the body. In everyday terminology, the microcirculation is "where the action is." Microcirculation is directly involved in such disease states as Alzheimers, inflammation, tumor growth, diabetic retinopathy, and wound healing- plus cardiovascular fitness is directly related to the formation of new capillaries in large muscles. Microvascular Research is the first book devoted exclusively to this vital systemic component of the cardiovascular system and provides up to date mini-reviews of normal functions and clinical states. The contributing authors are senior scientists with international reputation in their given disciplines. This two-volume set is a broad, interdisciplinary work that encompasses basic research and clinical applications equally. * Broad coverage of both basic and clinical aspects of microvasculature research * Contains 167 chapters from over 300 international authors * Each chapter includes key figures and annotated references


Coronary Microvascular Dysfunction

Coronary Microvascular Dysfunction

Author: Filippo Crea

Publisher: Springer Science & Business Media

Published: 2013-08-15

Total Pages: 263

ISBN-13: 8847053676

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In the past two decades a number of studies have shown that abnormalities in the function and structure of coronary microcirculation can be detected in several cardiovascular diseases. On the basis of the clinical setting in which it occurs, coronary microvascular dysfunction (CMD) can be classified into four types: CMD in the absence of any other cardiac disease; CMD in myocardial diseases; CMD in obstructive epicardial coronary artery disease; and iatrogenic CMD. In some instances CMD represents an epiphenomenon, whereas in others it represents an important marker of risk or may contribute to the pathogenesis of myocardial ischemia, thus becoming a possible therapeutic target. This book provides an update on coronary physiology and a systematic assessment of microvascular abnormalities in cardiovascular diseases, in the hope that it will assist clinicians in prevention, detection and management of CMD in their everyday activity.


Encyclopedia of Cardiovascular Research and Medicine

Encyclopedia of Cardiovascular Research and Medicine

Author:

Publisher: Elsevier

Published: 2017-11-27

Total Pages: 2854

ISBN-13: 012805154X

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Encyclopedia of Cardiovascular Research and Medicine, Four Volume Set offers researchers over 200 articles covering every aspect of cardiovascular research and medicine, including fully annotated figures, abundant color illustrations and links to supplementary datasets and references. With contributions from top experts in the field, this book is the most reputable and easily searchable resource of cardiovascular-focused basic and translational content for students, researchers, clinicians and teaching faculty across the biomedical and medical sciences. The panel of authors chosen from an international board of leading scholars renders the text trustworthy, contemporary and representative of the global scientific expertise in these domains. The book's thematic structuring of sections and in-depth breakdown of topics encourages user-friendly, easily searchable chapters. Cross-references to related articles and links to further reading and references will further guide readers to a full understanding of the topics under discussion. Readers will find an unparalleled, one-stop resource exploring all major aspects of cardiovascular research and medicine. Presents comprehensive coverage of every aspect of cardiovascular medicine and research Offers readers a broad, interdisciplinary overview of the concepts in cardiovascular research and medicine with applications across biomedical research Includes reputable, foundational content on genetics, cancer, immunology, cell biology and molecular biology Provides a multi-media enriched color-illustrated text with high quality images, graphs and tables.


Inflammation and the Microcirculation

Inflammation and the Microcirculation

Author: D. Neil Granger

Publisher: Morgan & Claypool Publishers

Published: 2010

Total Pages: 99

ISBN-13: 1615041656

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The microcirculation is highly responsive to, and a vital participant in, the inflammatory response. All segments of the microvasculature (arterioles, capillaries, and venules) exhibit characteristic phenotypic changes during inflammation that appear to be directed toward enhancing the delivery of inflammatory cells to the injured/infected tissue, isolating the region from healthy tissue and the systemic circulation, and setting the stage for tissue repair and regeneration. The best characterized responses of the microcirculation to inflammation include impaired vasomotor function, reduced capillary perfusion, adhesion of leukocytes and platelets, activation of the coagulation cascade, and enhanced thrombosis, increased vascular permeability, and an increase in the rate of proliferation of blood and lymphatic vessels. A variety of cells that normally circulate in blood (leukocytes, platelets) or reside within the vessel wall (endothelial cells, pericytes) or in the perivascular space (mast cells, macrophages) are activated in response to inflammation. The activation products and chemical mediators released from these cells act through different well-characterized signaling pathways to induce the phenotypic changes in microvessel function that accompany inflammation. Drugs that target a specific microvascular response to inflammation, such as leukocyte-endothelial cell adhesion or angiogenesis, have shown promise in both the preclinical and clinical studies of inflammatory disease. Future research efforts in this area will likely identify new avenues for therapeutic intervention in inflammation. Table of Contents: Introduction / Historical Perspectives / Anatomical Considerations / Impaired Vasomotor Responses / Capillary Perfusion / Angiogenesis / Leukocyte-Endothelial Cell Adhesion / Platelet-Vessel Wall Interactions / Coagulation and Thrombosis / Endothelial Barrier Dysfunction / Epilogue / References


Raising of Microvascular Flaps

Raising of Microvascular Flaps

Author: Klaus-Dietrich Wolff

Publisher: Springer

Published: 2017-10-25

Total Pages: 320

ISBN-13: 3319536702

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- Clearly illustrated with over 112 color illustrations to show all aspects of surgeries.


Atherosclerosis Pathogenesis and Microvascular Dysfunction

Atherosclerosis Pathogenesis and Microvascular Dysfunction

Author: Axel Haverich

Publisher: Springer

Published: 2019-07-23

Total Pages: 135

ISBN-13: 3030202453

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This book provides new perspectives on the pathogenesis of atherosclerosis. Chapters cover atherosclerosis risk factors, the effect of growth and aging on vascular architecture, and the crucial role the microvasculature plays in atherosclerosis development. Microvascular dysfunction would explain why the well-known risk factors actually put individuals at higher risk. This pathomechanism would also hold true not only for obstructive atheroma formation but also for aneurysmal dilatation as well as for aortic and peripheral artery dissection. When seen through this lens, novel preventive and therapeutic opportunities can be envisioned. Atherosclerosis Pathogenesis and Microvascular Dysfunction proposes a single unifying mechanism of atherosclerosis development and describes potential preventative and therapeutic avenues based on this concept. It therefore represents a timely and valuable resource for internal medicine, cardiology, angiology cardiovascular surgeons, pathology clinicians, researchers, trainees, and students.


Advances in Blood Research and Application: 2013 Edition

Advances in Blood Research and Application: 2013 Edition

Author:

Publisher: ScholarlyEditions

Published: 2013-06-21

Total Pages: 782

ISBN-13: 1481694065

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Advances in Blood Research and Application / 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Plasma. The editors have built Advances in Blood Research and Application: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Plasma in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Advances in Blood Research and Application: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.


Issues in Circulatory and Lymphatic Research: 2011 Edition

Issues in Circulatory and Lymphatic Research: 2011 Edition

Author:

Publisher: ScholarlyEditions

Published: 2012-01-09

Total Pages: 1258

ISBN-13: 1464965714

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Issues in Circulatory and Lymphatic Research: 2011 Edition is a ScholarlyEditions™ eBook that delivers timely, authoritative, and comprehensive information about Circulatory and Lymphatic Research. The editors have built Issues in Circulatory and Lymphatic Research: 2011 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Circulatory and Lymphatic Research in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Circulatory and Lymphatic Research: 2011 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.


Issues in Circulatory and Lymphatic Research: 2012 Edition

Issues in Circulatory and Lymphatic Research: 2012 Edition

Author:

Publisher: ScholarlyEditions

Published: 2013-01-10

Total Pages: 82

ISBN-13: 1481648616

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Issues in Circulatory and Lymphatic Research: 2012 Edition is a ScholarlyBrief™ that delivers timely, authoritative, comprehensive, and specialized information about Angiology in a concise format. The editors have built Issues in Circulatory and Lymphatic Research: 2012 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Angiology in this eBook to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Circulatory and Lymphatic Research: 2012 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.


Issues in Circulatory and Lymphatic Research: 2013 Edition

Issues in Circulatory and Lymphatic Research: 2013 Edition

Author:

Publisher: ScholarlyEditions

Published: 2013-05-01

Total Pages: 391

ISBN-13: 1490106332

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Issues in Circulatory and Lymphatic Research: 2013 Edition is a ScholarlyEditions™ book that delivers timely, authoritative, and comprehensive information about Angiology. The editors have built Issues in Circulatory and Lymphatic Research: 2013 Edition on the vast information databases of ScholarlyNews.™ You can expect the information about Angiology in this book to be deeper than what you can access anywhere else, as well as consistently reliable, authoritative, informed, and relevant. The content of Issues in Circulatory and Lymphatic Research: 2013 Edition has been produced by the world’s leading scientists, engineers, analysts, research institutions, and companies. All of the content is from peer-reviewed sources, and all of it is written, assembled, and edited by the editors at ScholarlyEditions™ and available exclusively from us. You now have a source you can cite with authority, confidence, and credibility. More information is available at http://www.ScholarlyEditions.com/.