Advances in Microfluidics Technology for Diagnostics and Detection

Advances in Microfluidics Technology for Diagnostics and Detection

Author: David Kinahan

Publisher: MDPI

Published: 2021-09-06

Total Pages: 123

ISBN-13: 3036513663

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Microfluidics and lab-on-a-chip have, in recent years, come to the forefront in diagnostics and detection. At point-of-care, in the emergency room, and at the hospital bed or GP clinic, lab-on-a-chip offers the potential to rapidly detect time-critical and life-threatening diseases such as sepsis and bacterial meningitis. Furthermore, portable and user-friendly diagnostic platforms can enable disease diagnostics and detection in resource-poor settings where centralised laboratory facilities may not be available. At point-of-use, microfluidics and lab-on-chip can be applied in the field to rapidly identify plant pathogens, thus reducing the need for damaging broad spectrum pesticides while also reducing food losses. Microfluidics can also be applied to the continuous monitoring of water quality and can support policy-makers and protection agencies in protecting the environment. Perhaps most excitingly, microfluidics also offers the potential to enable entirely new diagnostic tests that cannot be implemented using conventional laboratory tools. Examples of microfluidics at the frontier of new medical diagnostic tests include early detection of cancers through circulating tumour cells (CTCs) and highly sensitive genetic tests using droplet-based digital PCR. This Special Issue on “Advances in Microfluidics Technology for Diagnostics and Detection” aims to gather outstanding research and to carry out comprehensive coverage of all aspects related to microfluidics in diagnostics and detection.


Diagnostic Devices with Microfluidics

Diagnostic Devices with Microfluidics

Author: Francesco Piraino

Publisher: CRC Press

Published: 2017-06-26

Total Pages: 226

ISBN-13: 1351650483

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This book provides a current view of the research and commercial landscape of diagnostics devices, particularly those that utilize microscale technologies, intended for both patient and laboratory use. Common diagnostic devices that are based on microfluidic principles include glucose sensors for diabetic patients and over-the-counter pregnancy tests. Other diagnostic devices are being developed to quickly test a patient for bacterial and viral infections, and other diseases. The chapters, written by experts from around the world, discuss how to fabricate, apply, and market microfluidic diagnostic chips – for lab and at-home use. Most importantly, the book also contains a discussion of topics relevant to the private sector, including patient-focused, market-oriented development of diagnostics devices. Chapter 9 of this book is freely available as a downloadable Open Access PDF under a CC-BY 3.0 license. https://s3-us-west-2.amazonaws.com/tandfbis/rt-files/docs/Open+Access+Chapters/9781498772938_oachapter9.pdf


3D Printed Microfluidic Devices

3D Printed Microfluidic Devices

Author: Savas Tasoglu

Publisher: MDPI

Published: 2019-01-10

Total Pages: 213

ISBN-13: 3038974676

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This book is a printed edition of the Special Issue "3D Printed Microfluidic Devices" that was published in Micromachines


Paper Microfluidics

Paper Microfluidics

Author: Shantanu Bhattacharya

Publisher: Springer Nature

Published: 2019-10-08

Total Pages: 231

ISBN-13: 981150489X

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This volume provides an overview of the recent advances in the field of paper microfluidics, whose innumerable research domains have stimulated considerable efforts to the development of rapid, cost-effective and simplified point-of-care diagnostic systems. The book is divided into three parts viz. theoretical background of paper microfluidics, fabrication techniques for paper-based devices, and broad applications. Each chapter of the book is self-explanatory and focuses on a specific topic and its relation to paper microfluidics and starts with a brief description of the topic’s physical background, essential definitions, and a short story of the recent progress in the relevant field. The book also covers the future outlook, remaining challenges, and emerging opportunities. This book shall be a tremendous up-to-date resource for researchers working in the area globally.


Advanced Microfluidics Based Point-of-Care Diagnostics

Advanced Microfluidics Based Point-of-Care Diagnostics

Author: Raju Khan

Publisher: CRC Press

Published: 2021-03-11

Total Pages: 416

ISBN-13: 1000548376

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This book provides a well-focused and comprehensive overview of novel technologies involved in advanced microfluidics based diagnosis via various types of prognostic and diagnostic biomarkers. This authors examine microfluidics based diagnosis in the biomedical field as an upcoming field with extensive applications. It provides a unique approach and comprehensive technology overview for diagnosis management towards early stages of various bioanalytes via cancer diagnostics diabetes, alzheimer disease, toxicity in food products, brain and retinal diseases, cardiovascular diseases, and bacterial infections etc. Thus, this book would encompass a combinatorial approach of medical science, engineering and biomedical technology. The authors provide a well-focused and comprehensive overview of novel technologies involved in advanced microfluidics based diagnosis via various types of prognostic and diagnostic biomarkers. Moreover, this book contains detailed description on the diagnosis of novel techniques. This book would serve as a guide for students, scientists, researchers, and microfluidics based point of care technologies via smart diagnostics and to plan future research in this valuable field.


Microfluidics and Lab-on-a-Chip

Microfluidics and Lab-on-a-Chip

Author: Andreas Manz

Publisher: Royal Society of Chemistry

Published: 2020-09-24

Total Pages: 307

ISBN-13: 1782628339

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Responding to the need for an affordable, easy-to-read textbook that introduces microfluidics to undergraduate and postgraduate students, this concise book will provide a broad overview of the important theoretical and practical aspects of microfluidics and lab-on-a-chip, as well as its applications.


Advanced Microfluidics Based Point-Of-Care Diagnostics

Advanced Microfluidics Based Point-Of-Care Diagnostics

Author: Raju Khan

Publisher:

Published: 2022

Total Pages: 0

ISBN-13: 9781032218120

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"This book provides a well-focused and comprehensive overview of novel technologies involved in advanced microfluidics based diagnosis via various types of prognostic and diagnostic biomarkers. Moreover, i also contains detailed descriptions on the diagnosis of novel techniques"--


Paper-based Diagnostics

Paper-based Diagnostics

Author: Kevin J. Land

Publisher: Springer

Published: 2018-12-11

Total Pages: 225

ISBN-13: 331996870X

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This book explores the status of paper-based diagnostic solutions, or Microfluidics 2.0. The contributors explore: how paper-based tests can be widely distributed and utilized by semi-skilled personnel; how close to commercial applications the technology has become, and what is still required to make paper-based diagnostics the game-changer it can be. The technology is examined through the lens of the World Health Organization’s ASSURED criteria for low-resource countries (Affordable, Sensitive, Specific, User-friendly, Rapid and robust, Equipment-free, and Deliverable to end-users). Its applications have to include: health technology, environmental technology, food safety, and more. This book is appropriate for researchers in these areas, as well as those interested in microfluidics, and includes chapters dedicated to principles such as theory of flow and surface treatments; components such as biomarkers and detection; and current methods of manufacturing. Discusses how paper-based diagnostics can be used in developing countries by comparing current diagnostic tests with the World Health Organization's ASSURED criteria Examines how paper-based diagnostics could be integrated with other technologies, such as printed electronics, and the Internet of Things. Outlines how semi-skilled personnel across a variety of fields can implement paper-based diagnostics


Laboratory Methods in Microfluidics

Laboratory Methods in Microfluidics

Author: Basant Giri

Publisher: Elsevier

Published: 2017-05-15

Total Pages: 179

ISBN-13: 0128132361

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Laboratory Methods in Microfluidics features a range of lab methods and techniques necessary to fully understand microfluidic technology applications. Microfluidics deals with the manipulation of small volumes of fluids at sub-millimeter scale domain channels. This exciting new field is becoming an increasingly popular subject both for research and education in various disciplines of science, including chemistry, chemical engineering and environmental science. The unique properties of microfluidic technologies, such as rapid sample processing and precise control of fluids in assay have made them attractive candidates to replace traditional experimental approaches. Practical for students, instructors, and researchers, this book provides a much-needed, comprehensive new laboratory reference in this rapidly growing and exciting new field of research. - Provides a number of detailed methods and instructions for experiments in microfluidics - Features an appendix that highlights several standard laboratory techniques, including reagent preparation plus a list of materials vendors for quick reference - Authored by a microfluidics expert with nearly a decade of research on the subject