Microbial Process Development

Microbial Process Development

Author: H. W. Doelle

Publisher: World Scientific

Published: 1994

Total Pages: 332

ISBN-13: 9789810215156

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This book outlines the vast potential of the microbial catalyst for present and future microbial process development without waste formation, leading to a clean environment. It is intended to inspire scientists and biochemical engineers to isolate new microorganisms from nature and to explore the optimal potential of the genotype before altering its code through genetical engineering. This book is structured to encourage the reader to use basic scientific and biochemical engineering concepts for the development of new and improved fermentation technology industries. It leads the reader from aspects of isolation, identification and preservation of microbial strains to the use of thermodynamics and their biochemistry to the final endproducts and their purification. Special emphasis is given to the restoration of our present and the preservation of our future environment using socioecological and biotechnological concepts. Drawing on many years of experience teaching and working in the Asia-Pacific and Africa, the author presents an interesting, informative and enlightening account of his knowledge in this field.


Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing

Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing

Author: Ganapathy Subramanian

Publisher: John Wiley & Sons

Published: 2021-12-20

Total Pages: 404

ISBN-13: 3527347690

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Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing Explore new trends in continuous biomanufacturing with contributions from leading practitioners in the field With the increasingly widespread acceptance and investment in the ??technology, the last decade has demonstrated the utility of continuous ??processing in the pharmaceutical industry. In Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing, distinguished biotechnologist Dr. Ganapathy Subramanian delivers a comprehensive exploration of the potential of the continuous processing of biological products and discussions of future directions in advancing continuous processing to meet new challenges and demands in the manufacture of therapeutic products. A stand-alone follow-up to the editor’s Continuous Biomanufacturing: Innovative Technologies and Methods published in 2017, this new edited volume focuses on critical aspects of process intensification, process control, and the digital transformation of biopharmaceutical processes. In addition to topics like the use of multivariant data analysis, regulatory concerns, and automation processes, the book also includes: Thorough introductions to capacitance sensors to control feeding strategies and the continuous production of viral vaccines Comprehensive explorations of strategies for the continuous upstream processing of induced microbial systems Practical discussions of preparative hydrophobic interaction chromatography and the design of modern protein-A-resins for continuous biomanufacturing In-depth examinations of bioprocess intensification approaches and the benefits of single use for process intensification Perfect for biotechnologists, bioengineers, pharmaceutical engineers, and process engineers, Process Control, Intensification, and Digitalisation in Continuous Biomanufacturing is also an indispensable resource for chemical engineers seeking a one-stop reference on continuous biomanufacturing.


Microbial Processes and Products

Microbial Processes and Products

Author: José-Luis Barredo

Publisher: Springer Science & Business Media

Published: 2008-02-05

Total Pages: 514

ISBN-13: 1592598471

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The development of biotechnology over the last 20 years, and particularly the use of recombinant DNA techniques, has rapidly expanded the opportu- ties for human benefits from living resources. Efforts to reduce pollution, p- vent environmental damage, combat microbial infection, improve food production, and so on can each involve fermentation or the environmental - lease of microorganisms. Many products of fermentation technology, such as alcoholic beverages, bread, antibiotics, amino acids, vitamins, enzymes, and others, have been influenced by the progress of recombinant DNA techniques. The development of new products or the more efficient manufacturing of those already being produced often involve the use of microorganisms as cell fac- ries for many productions and biotransformations. Microbial Processes and Products is intended to provide practical expe- mental laboratory procedures for a wide range of processes and products me- ated by microorganisms. Although not an exhaustive treatise, it provides a detailed “step-by-step” description of the most recent developments in such applied biotechnological processes. The detailed protocols we provide are cross-referenced in the Notes section, contain critical details, lists of problems and their troubleshooting, as well as safety recommendations that may not n- mally appear in journal articles and can be particularly useful for those un- miliar with specific techniques.


Process Development in Antibiotic Fermentations

Process Development in Antibiotic Fermentations

Author: C. T. Calam

Publisher: Cambridge University Press

Published: 1987-07-31

Total Pages: 232

ISBN-13: 9780521304900

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Process development in antibiotic fermentation is of microbiological and commercial importance and this book gives a consistent treatment of the area.


Fermentation Processes: Emerging and Conventional Technologies

Fermentation Processes: Emerging and Conventional Technologies

Author: Mohamed Koubaa

Publisher: John Wiley & Sons

Published: 2021-02-11

Total Pages: 240

ISBN-13: 1119505844

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Explores the use of conventional and novel technologies to enhance fermentation processes Fermentation Processes reviews the application of both conventional and emerging technologies for enhancing fermentation conditions, examining the principles and mechanisms of fermentation processes, the microorganisms used in bioprocesses, their implementation in industrial fermentation, and more. Designed for scientists and industry professionals alike, this authoritative and up-to-date volume describes how non-conventional technologies can be used to increase accessibly and bioavailability of substrates by microorganisms during fermentation, which in turn promotes microbial growth and can improve processes and productivity across the agri-food, nutraceutical, pharmaceutical, and beverage industries. The text begins by covering the conventional fermentation process, discussing cell division and growth kinetics, current technologies and developments in industrial fermentation processes, the parameters and modes of fermentation, various culture media, and the impact of culture conditions on fermentation processes. Subsequent chapters provide in-depth examination of the use of emerging technologies—such as pulsed electric fields, ultrasound, high-hydrostatic pressure, and microwave irradiation—for biomass fractionation and microbial stimulation. This authoritative resource: Explores emerging technologies that shorten fermentation time, accelerate substrate consumption, and increase microbial biomass Describes enhancing fermentation at conventional conditions by changing oxygenation, agitation, temperature, and other medium conditions Highlights the advantages of new technologies, such as reduced energy consumption and increased efficiency Discusses the integration and implementation of conventional and emerging technologies to meet consumer and industry demand Offers perspectives on the future direction of fermentation technologies and applications Fermentation Processes: Emerging and Conventional Technologies is ideal for microbiologists and bioprocess technologists in need of an up-to-date overview of the subject, and for instructors and students in courses such as bioprocess technology, microbiology, new product development, fermentation, food processing, biotechnology, and bioprocess engineering.


Microbial Energy Conversion

Microbial Energy Conversion

Author: Zhenhong Yuan

Publisher: Walter de Gruyter GmbH & Co KG

Published: 2018-05-22

Total Pages: 568

ISBN-13: 311042486X

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The book provides an overview on various microorganisms and their industrialization in energy conversion, such as ethanol fermentation, butanol fermentation, biogas fermentation and fossil energy conversion. It also covers microbial oil production, hydrogen production and electricity generation. The content is up to date and suits well for both researchers and industrial audiences.


New and Future Developments in Microbial Biotechnology and Bioengineering

New and Future Developments in Microbial Biotechnology and Bioengineering

Author: Ram Prasad

Publisher: Elsevier

Published: 2018-02-20

Total Pages: 506

ISBN-13: 0444639888

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Crop Improvement through Microbial Biotechnology explains how certain techniques can be used to manipulate plant growth and development, focusing on the cross-kingdom transfer of genes to incorporate novel phenotypes in plants, including the utilization of microbes at every step, from cloning and characterization, to the production of a genetically engineered plant. This book covers microbial biotechnology in sustainable agriculture, aiming to improve crop productivity under stress conditions. It includes sections on genes encoding avirulence factors of bacteria and fungi, viral coat proteins of plant viruses, chitinase from fungi, virulence factors from nematodes and mycoplasma, insecticidal toxins from Bacillus thuringiensis, and herbicide tolerance enzymes from bacteria. Introduces the principles of microbial biotechnology and its application in crop improvement Lists various new developments in enhancing plant productivity and efficiency Explains the mechanisms of plant/microbial interactions and the beneficial use of these interactions in crop improvement Explores various bacteria classes and their beneficial effects in plant growth and efficiency


Manual of Industrial Microbiology and Biotechnology

Manual of Industrial Microbiology and Biotechnology

Author: Arnold L. Demain

Publisher:

Published: 1999

Total Pages: 854

ISBN-13:

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The editors have enlisted a broad range of experts, including microbial ecologists, physiologists, geneticists, biochemists, molecular biologists, and biochemical engineers, who offer practical experience not found in texts and journals. This comprehensive perspective makes MIMB a valuable "how to" resource, the structure of which resembles the sequence of operation involved in the development of a commercial biological process and product.