This book describes the substantial progress recently made in the development of micro and nanorobotic systems, utilizing magnetic, optical, acoustic, electrical, and other actuation fields. It covers several areas of micro and nanorobotics including robotics, materials science, and biomedical engineering. Field-Driven Micro and Nanorobots for Biology and Medicine provides readers with fundamental physics at the micro and nano scales, state-of-the-art technical advances in field-driven micro and nanorobots, and applications in biological and biomedical disciplines.
Micro/Nano-robotics for Biomedical Applications features a system approach and incorporates modern methodologies in autonomous mobile robots for programmable and controllable micro/nano-robots aiming at biomedical applications. The book provides chapters of instructional materials in micro/nanorobotics for biomedical applications. The book features lecture units on micro/nanorobot components and techniques, including sensors, actuator, power supply, and micro/nano-fabrication and assembly. It also contains case studies on using micro/nano-robots in biomedical environments and in biomedicine, as well as a design example to conceptually develop a Vitamin-pill sized robot to enter human’s gastrointestinal tract. Laboratory modules to teach robot navigation and cooperation methods suitable to biomedical applications will be also provided based on existing simulation and robot platforms.
Micro/nanorobots have emerged as functional agents and versatile tools for investigating the complex microenvironments within biological systems. Operating at a scale comparable to cells, these micro/nanorobots offer controllable motion and customizable characteristics, whilst swarming micro/nanorobots exhibit exceptional efficiency, robustness, and adaptivity. As a result, these active particles hold significant potential for interacting with living cells, diseased tissues, and organs, offering viable approaches to uncovering natural principles of development and addressing diseases such as drug-tolerant infections and bacterial self-organization. To tackle these challenges, functionalized micro/nanorobots, through active intervention, can yield substantial effects on the development and treatment of cellular environments, bacterial biofilms, and tissue restoration. In this regard, we are organizing a special issue to delineate the current state of the art of micro/nanorobots in biological contexts and to advance therapeutics by elucidating the underlying mechanisms in living systems. In the contemporary era of advancing nanomedicine, the utilization of micro/nanorobots in clinical therapy is still in its nascent stages within the realm of modern healthcare. Biomedical and biological environments hold immense promise as platforms for these active agents, showcasing remarkable functionalities and efficacy in vitro, ex vivo, and in vivo. Micro/nanorobots have the capacity to emulate the behaviors of living cells, particularly bacteria, which play a crucial role in microbial infections, thus impacting public health and medical devices. These active agents possess the potential to overcome biological barriers and enable targeted therapies for various healthcare issues, including the prevention and treatment of diseased tissues and biofilms, which will significantly enhance the minimally invasive operations and remote treatments for the next-generation human healthcare system. The objectives of this research topic are threefold: (1) to investigate the novel functionalities of micro/nanorobots in biological contexts, (2) to unravel the underlying principles of cell, tissue, and organ development, and (3) to innovate active therapeutic approaches for addressing diseased tissues and microbial biofilms
This book provides a comprehensive overview of how use of micro- and nanotechnology (MNT) has allowed major new advance in vaccine development research, and the challenges that immunologists face in making further progress. MNT allows the creation of particles that exploit the inherent ability of the human immune system to recognize small particles such as viruses and toxins. In combination with minimal protective epitope design, this permits the creation of immunogenic particles that stimulate a response against the targeted pathogen. The finely tuned response of the human immune system to small particles makes it unsurprising that many of the lead adjuvants and vaccine delivery systems currently under investigation are based on nanoparticles. Provides a comprehensive and unparalleled overview of the role of micro- and nanotechnology in vaccine development Allows researchers to quickly familiarize themselves with the broad spectrum of vaccines and how micro- and nanotechnologies are applied to their development Includes a combination of overview chapters setting out general principles, and focused content dealing with specific vaccines, making it useful to readers from a variety of disciplines
Micro/Nano Robotics and Automation technologies have rapidly grown associated with the growth of Micro and Nanotechnologies. This book presents a summary of fundamentals in micro-nano scale engineering and the current state of the art of these technologies. “Micro-Nanorobotic Manipulation Systems and their Applications” introduces these advanced technologies from the basics and applications aspects of Micro/Nano-Robotics and Automation from the prospective micro/nano-scale manipulation. The book is organized in 9 chapters including an overview chapter of Micro/Nanorobotics and Automation technology from the historical view and important related research works. Further chapters are devoted to the physics of micro-nano fields as well as to material and science, microscopes, fabrication technology, importance of biological cell, and control techniques. Furthermore important examples, applications and a concise summary of Micro-Nanorobotics and Automation technologies are given.
Micro/Nano-robotics for Biomedical Applications features a system approach and incorporates modern methodologies in autonomous mobile robots for programmable and controllable micro/nano-robots aiming at biomedical applications. The book provides chapters of instructional materials in micro/nanorobotics for biomedical applications. The book features lecture units on micro/nanorobot components and techniques, including sensors, actuator, power supply, and micro/nano-fabrication and assembly. It also contains case studies on using micro/nano-robots in biomedical environments and in biomedicine, as well as a design example to conceptually develop a Vitamin-pill sized robot to enter human’s gastrointestinal tract. Laboratory modules to teach robot navigation and cooperation methods suitable to biomedical applications will be also provided based on existing simulation and robot platforms.
Nanorobots can be defined as intelligent systems with overall dimensions at or below the micrometer range that are made of assemblies of nanoscale components with individual dimensions ranging between 1 to 100 nm. These devices can now perform a wide variety of tasks at the nanoscale in a wide variety of fields including but not limited to fields such as manufacturing, medicine, supply chain, biology, and aerospace. Nanorobotics: Current Approaches and Techniques offers a comprehensive overview of this emerging interdisciplinary field with a wide ranging discussion that includes nano-manipulation and industrial nanorobotics, nanorobotic manipulation in biology and medicine, nanorobotic sensing, navigation and swarm behavior and CNT, and protein and DNA-based nanorobotics.
Learning Bio-Micro-Nanotechnology is a primer on micro/nanotechnology that teaches the vocabulary, fundamental concepts, and applications of micro/nanotechnology in biology, chemistry, physics, engineering, electronics, computers, biomedicine, microscopy, ethics, and risks to humankind. It provides an introduction into the small world with a low fo
Signal Measurement and Estimation Techniques for Micro and Nanotechnology discusses micro, nano and robotic cells and gives a state-of-the-art presentation of the different techniques and solutions to measure and estimate signals at the micro and nano scale. New technologies and applications such as micromanipulation (artificial components, biological objects), micro-assembly (MEMS, MOEMS, NEMS) and material and surface force characterization are covered. The importance of sensing at the micro and nano scale is presented as a key issue in control systems, as well as for understanding the physical phenomena of these systems. The book also: Explains issues that make signal measurement and estimation techniques difficult at the micro-nano-scale and offers solutions Discusses automated micro-assembly, and control of micro-nano robotic devices Presents and links signal measurement and estimation techniques for micro-nano scale systems with microfabrication methods, sensors integration and control schemes Signal Measurement and Estimation Techniques for Micro and Nanotechnology is a must-read for researchers and engineers working in MEMS and control systems.
Smart Materials-Based Actuators at the Micro/Nano-Scale: Characterization, Control, and Applications gives a state of the art of emerging techniques to the characterization and control of actuators based on smart materials working at the micro/nano scale. The book aims to characterize some commonly used structures based on piezoelectric and electroactive polymeric actuators and also focuses on various and emerging techniques employed to control them. This book also includes two of the most emerging topics and applications: nanorobotics and cells micro/nano-manipulation.
