If You Give a Mouse Metformin
If You Give a Mouse Metformin

Author: Nikhil Krishnan

Publisher:

Published: 2020-07-14

Total Pages: 45

ISBN-13:

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Learn how clinical trials work in a fun, satirical, and kid-friendly way! A scientist and a mouse learn what it takes to develop a drug. Along the way they'll encounter a cast of characters including doctors, the FDA, other animals, and the clinical trial complex. Have you ever wanted to know how drug development works, but too scared to ask? Now you can say you're buying a book for a child, but it's actually for you. This book is a great gift for anyone in the healthcare field, or any baby that wants to learn how double-blind placebo controlled trials work. A great gag gift for baby showers, secret Santa, holidays, weddings, divorces (?), med school graduations, work anniversaries, new employees. An Out-Of-Pocket Production. Learn more at www.outofpocket.health

Drug-Induced Liver Injury
Drug-Induced Liver Injury

Author:

Publisher: Academic Press

Published: 2019-07-13

Total Pages: 288

ISBN-13: 0128173173

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Drug-Induced Liver Injury, Volume 85, the newest volume in the Advances in Pharmacology series, presents a variety of chapters from the best authors in the field. Chapters in this new release include Cell death mechanisms in DILI, Mitochondria in DILI, Primary hepatocytes and their cultures for the testing of drug-induced liver injury, MetaHeps an alternate approach to identify IDILI, Autophagy and DILI, Biomarkers and DILI, Regeneration and DILI, Drug-induced liver injury in obesity and nonalcoholic fatty liver disease, Mechanisms of Idiosyncratic Drug-Induced Liver Injury, the Evaluation and Treatment of Acetaminophen Toxicity, and much more. Includes the authority and expertise of leading contributors in pharmacology Presents the latest release in the Advances in Pharmacology series

Polycystic Ovary Syndrome
Polycystic Ovary Syndrome

Author: Andrea Dunaif

Publisher: Springer Science & Business Media

Published: 2008-01-12

Total Pages: 361

ISBN-13: 1597451088

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This volume includes the latest diagnostic criteria for PCOS and comprises the most up-to-date information about the genetic features and pathogenesis of PCOS. It critically reviews the methodological approaches and the evidence for various PCOS susceptibility genes. The book also discusses additional familial phenotypes of PCOS and their potential genetic basis. All four editors of this title are extremely prominent in the field of PCOS.

Metformin - The Gold Standard
Metformin - The Gold Standard

Author: Clifford J. Bailey

Publisher: Wiley

Published: 2008-05-05

Total Pages: 0

ISBN-13: 9780470725412

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Metformin may play in important role in the future in helping to prevent the development of diabetes: it is a strong candidate therapy for delaying the onset of the disease and potentially as part of a treatment programme to correct features of the metabolic syndrome. This book celebrates 50 years of research into metformin and its use in the treatment of diabetes. Metformin is still the drug of choice for managing patients with type 2 diabetes and all new drugs are tested in comparison with this, the gold standard. Comprising seven sections, addressing different aspects of research on metformin and its applications, this book is edited by a world class team of expert diabetologists and beautifully presented in two colour throughout. It also includes a bibliography of all papers published on metformin and a complete list of all authors on those papers.

Metformin
Metformin

Author: Juber Akhtar

Publisher: BoD – Books on Demand

Published: 2021-12-15

Total Pages: 155

ISBN-13: 1839696052

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Type 2 diabetes (T2D), also known as non-insulin-dependent diabetes mellitus (NIDDM), is a condition in which cells fail to respond to insulin properly. As the disease progresses, the body does not produce enough insulin. There are several classes of anti-diabetic medications available, including the oral agent metformin. This medication is recommended as first-line treatment for T2D, except for those patients with severe kidney or liver problems. This book discusses the molecular mechanism, pharmacokinetics, and uses of metformin, as well as presents information on adverse drug reactions, drug interactions, and the potential use of metformin in tuberculosis.

Hepatotoxicity
Hepatotoxicity

Author: Hyman J. Zimmerman

Publisher: Lippincott Williams & Wilkins

Published: 1999

Total Pages: 848

ISBN-13: 9780781719520

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Written by the foremost authority in the field, this volume is a comprehensive review of the multifaceted phenomenon of hepatotoxicity. Dr. Zimmerman examines the interface between chemicals and the liver; the latest research in experimental hepatotoxicology; the hepatotoxic risks of household, industrial, and environmental chemicals; and the adverse effects of drugs on the liver. This thoroughly revised, updated Second Edition features a greatly expanded section on the wide variety of drugs that can cause liver injury. For quick reference, an appendix lists these medications and their associated hepatic injuries. Also included are in-depth discussions of drug metabolism and factors affecting susceptibility to liver injury.

Metformin
Metformin

Author: Anca Pantea Stoian

Publisher: BoD – Books on Demand

Published: 2020-05-27

Total Pages: 244

ISBN-13: 1838804277

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The book “Metformin” aims to bring to light new concepts and trends related to the many metformin therapeutic features. After a history of over 60 years, with moments of decline and spectacular returns, metformin can now be regarded as a universal panacea, the valences of its therapeutics being increasingly appreciated, both in the background treatment of diabetes and pre-diabetes, but also in reproductive pathology, cancer, cardiovascular disease, and antiageing. In this respect, the mechanisms of action and the pharmacodynamics of metformin seem to be incompletely known, a number of current studies have revealed new action valences.

Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases
Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases

Author: Solomon Habtemariam

Publisher: Academic Press

Published: 2019-06-08

Total Pages: 1180

ISBN-13: 0081029233

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Medicinal Foods as Potential Therapies for Type-2 Diabetes and Associated Diseases: The Chemical and Pharmacological Basis of their Action focuses on active pharmacological principles that modulate diabetes, associated risk factors, complications and the mechanism of action of widely used anti-diabetic herbal plants—rather than just the nutritional composition of certain foods. The book provides up-to-date information on acclaimed antidiabetic super fruits, spices and other food ingredients. Sections cover diabetes and obesity at the global level, the physiological control of carbohydrate and lipid metabolism, the pathophysiology of type-2 diabetes, the chemistry and pharmacology of a variety of spices, and much more. This book will be invaluable for research scientists and students in the medical and pharmaceutical sciences, medicinal chemistry, herbal medicine, drug discovery/development, nutrition science, and for herbal practitioners and those from the nutraceutical and pharm industries. Provides background knowledge on type-2 diabetes and its pathophysiology and therapeutic targets down to the molecular level Explores, in detail, the chemistry or secondary metabolites of the indicated foods that potentially modify diabetes and/or associated diseases Examines the pharmacological findings on medicinal foods, including available clinical trials

Drug-Induced Liver Disease
Drug-Induced Liver Disease

Author: Neil Kaplowitz

Publisher: CRC Press

Published: 2002-10-16

Total Pages: 790

ISBN-13: 0203909127

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Featuring more than 4100 references, Drug-Induced Liver Disease will be an invaluable reference for gastroenterologists, hepatologists, family physicians, internists, pathologists, pharmacists, pharmacologists, and clinical toxicologists, and graduate and medical school students in these disciplines.