Metabolism and Medicine
Metabolism and Medicine

Author: Brian Fertig

Publisher: CRC Press

Published: 2022-01-25

Total Pages: 369

ISBN-13: 1000472132

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Chronic disease states of aging should be viewed through the prism of metabolism and biophysical processes at all levels of physiological organization present in the human body. This book describes the building blocks of understanding from a reasonable but not high-level technical language viewpoint, employing the perspective of a clinical physician. It brings together concepts from five specific branches of physics relevant to biology and medicine, namely, biophysics, classical electromagnetism, thermodynamics, systems biology and quantum mechanics. Key Features: Broad and up-to-date overview of the field of metabolism, especially connecting the spectrum of topics that range from modern physical underpinnings with cell biology to clinical practice. Provides a deeper basic science and interdisciplinary understanding of biological systems that broaden the perspectives and therapeutic problem solving. Introduces the concept of the Physiological Fitness Landscape, which is inspired by the physics of phase transitions This first volume in a two-volume set, primarily targets an audience of clinical and science students, biomedical researchers and physicians who would benefit from understanding each other’s language.

Metabolism and Medicine
Metabolism and Medicine

Author: Brian Fertig

Publisher: CRC Press

Published: 2021-11-12

Total Pages: 858

ISBN-13: 9781032126692

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Chronic disease states of aging should be viewed through the prism of metabolism and biophysical processes at all levels of physiological organization present in the human body. The first volumeconnects these insights to what causes them to go awry in the context of unhealthy human behaviors and aging, aiming to buttress scientific creativity. It also provides links between the art and science of medicine that strengthens problem-solving in patient care. New and important discoveries in the area of metabolic health and metabolic diseases are discussed in exquisite detail. The second volume describes the building blocks of understanding from a reasonable but not high-level technical language viewpoint, employing the perspective of a clinical physician. It brings together concepts from five specific branches of physics relevant to biology and medicine, namely, biophysics, classical electromagnetism, thermodynamics, systems biology and quantum mechanics.

Principles and Practice of Endocrinology and Metabolism
Principles and Practice of Endocrinology and Metabolism

Author: Kenneth L. Becker

Publisher: Lippincott Williams & Wilkins

Published: 2001

Total Pages: 2500

ISBN-13: 9780781717502

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Established as the foremost text in the field, Principles and Practice of Endocrinology and Metabolism is now in its thoroughly revised, updated Third Edition. This practical, clinically relevant, and comprehensive text covers the entire field of endocrinology and metabolism, including the diffuse endocrine system; morphology and physiology; diagnosis and treatment of endocrine diseases; endocrinology of the female; hormones and cancer; and much more. The Third Edition contains new chapters reflecting the latest advances and features expanded coverage of genetics and the endocrinology of sepsis. More than 1,400 illustrations complement the text. A drug formulary appears at the back of the book.

Essentials of Endocrinology and Metabolism
Essentials of Endocrinology and Metabolism

Author: Fredric E. Wondisford

Publisher: Springer Nature

Published: 2020-05-23

Total Pages: 279

ISBN-13: 3030395723

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Developed from time-tested material utilized in endocrinology courses for medical students, this comprehensive and practical guide draws together a number of related disciplines to create a straightforward and accessible approach to the study of endocrine and metabolic diseases. Designed with the student in mind, each of the main endocrine organs and disorders are covered in thematic sections on diabetes, thyroid disorders, calcium disorders, adrenal disorders, and hypothalamus and pituitary disorders. Opening with clear learning objectives, chapters within each section discuss core concepts, anatomy, embryology, histology, testing, diagnosis and pharmacology, and include clinical case scenarios and multiple choice review questions. Full-color figures and diagrams enhance and extend the content. Perfect for in-class reference or board licensing review, Essentials of Endocrinology and Metabolism is an indispensable resource for medical and nursing students alike.

Isotope Tracers in Metabolic Research
Isotope Tracers in Metabolic Research

Author: Robert R. Wolfe

Publisher: John Wiley & Sons

Published: 2004-10-18

Total Pages: 494

ISBN-13: 9780471462095

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In the past few years, the number of applications of tracers for in vivo biomedical studies has greatly increased. New analytical tools at the genetic and protein levels have spurred this growth, opening the door for a deeper understanding of metabolic events. This in turn promises to yield significant advances in the understanding and treatment of human disease. Now fully revised and expanded, Isotope Tracers in Metabolic Research, Second Edition is the established definitive text on stable and radioactive isotope tracers. In unique, multidisciplinary fashion, it presents comprehensive coverage of new methodological, mathematical, and theoretical approaches. This new Second Edition includes: All-new chapters on nuclear magnetic resonance, mass isotopomer analysis, and methods of protein metabolism analysis A completely updated categorized list of over 750 references Major advances in the development of mass isotopomer and positional isotopomer techniques, noninvasive isotope techniques for studying metabolic pathways, hyphenated techniques, and new tracer techniques The latest developments in quantification of DNA synthesis and mass spectrometry spurred by genome sequencing and proteomics New coverage of mathematical modeling Expanded coverage of microdialysis probes, laboratory procedures, and regulatory issues related to human studies In this complete guide to performing tracer studies, the authors systematically cover tracer selection, modeling considerations, sample derivitization, mass spectrometry analysis, and data interpretation. Problems and discussion questions highlight key points in each chapter. Isotope Tracers in Metabolic Research, Second Edition offers students and researchers a comprehensive, practical resource for utilizing the latest tracer methodologies.

Drug Metabolism
Drug Metabolism

Author: Jack P. Uetrecht

Publisher: CRC Press

Published: 2007-06-21

Total Pages: 191

ISBN-13: 1420061089

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In order to understand drug metabolism at its most fundamental level, pharmaceutical scientists must be able to analyze drug compound structures and predict possible metabolic pathways in order to avoid the risk of adverse reactions that lead to the withdrawal of a drug from the market. This comprehensive textbook will aid in guiding students throu

Clinical Endocrinology and Metabolism
Clinical Endocrinology and Metabolism

Author: Pauline Camacho

Publisher: CRC Press

Published: 2011-02-04

Total Pages: 312

ISBN-13: 1482261308

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This compact yet complete guide to the diagnosis and treatment of endocrine and metabolic disorders combines the advantages of a short text book with those of an atlas, and provides thorough discussion of each disease supported by a wealth of images. Each topic is covered by a specialist contributor. While reflecting the great advances in biochemic

Metabolic Engineering
Metabolic Engineering

Author: Jens Nielsen

Publisher: Springer

Published: 2003-07-03

Total Pages: 193

ISBN-13: 3540453008

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Metabolic engineering is a rapidly evolving field that is being applied for the optimization of many different industrial processes. In this issue of Advances in Biochemical Engineering/Biotechnology, developments in different areas of metabolic engineering are reviewed. The contributions discuss the application of metabolic engineering in the improvement of yield and productivity - illustrated by amino acid production and the production of novel compounds - in the production of polyketides and extension of the substrate range - and in the engineering of S. cerevisiae for xylose metabolism, and the improvement of a complex biotransformation process.

A Handbook of Bioanalysis and Drug Metabolism
A Handbook of Bioanalysis and Drug Metabolism

Author: Gary Evans

Publisher: CRC Press

Published: 2021-10-15

Total Pages: 490

ISBN-13: 1134477368

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Recent years have seen a greater industrial emphasis in undergraduate and postgraduate courses in the pharmaceutical and chemical sciences. However, textbooks have been slow to adapt, leaving the field without a text/reference that is both instructional and practical in the industrial setting – until now. A Handbook of Bioanalysis and Drug Metabolismis a stimulating new text that examines the techniques, methodology, and theory of bioanalysis, pharmacokinetics, and metabolism from the perspective of scientists with extensive professional experience in drug discovery and development. These three areas of research help drug developers to optimize the active component within potential drugs thereby increasing their effectiveness, and to provide safety and efficacy information required by regulators when granting a drug license. Professionals with extensive experience in drug discovery and development as well as specialized knowledge of the individual topics contributed to each chapter to create a current and well-credentialed text. It covers topics such as high performance liquid chromatography, protein binding, pharmacokinetics and drug–drug interactions. The unique industrial perspective helps to reinforce theory and develop valuable analytical and interpreting skills. This text is an invaluable guide to students in courses such as pharmaceutical science, pharmacology, chemistry, physiology and toxicology, as well as professionals in the biotechnology industry.