Melatonin and the Mammalian Pineal Gland

Melatonin and the Mammalian Pineal Gland

Author: Josephine Arendt

Publisher: Springer Science & Business Media

Published: 1994-12-31

Total Pages: 364

ISBN-13: 9780412536007

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This volume provides the reader with an overview of an intriguing and interdisciplinary field of research. For the first time the mammalian pineal gland, its mode of action and its physiological effects are discussed in a comprehensive, single-authored work.


The Pineal Gland and Cancer

The Pineal Gland and Cancer

Author: C. Bartsch

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 979

ISBN-13: 364259512X

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The link between the pineal gland and cancer is a rapidly emerging research field due to promising experimental and clinical trials with melatonin. The pineal gland acts as a transducer of environmental light to regulate rhythmic processes, including reproductive function in seasonally breeding animals and the entrainment of circadian rhythms, such as the sleep-wake cycle, in man. This book elucidates the physiological significance of the pineal gland and surveys phenomena and mechanisms of pineal - tumor interaction at the neuroendocrine, neuroimmune, neural, and molecular levels. Yet unidentified low-molecular-weight pineal substances with tumor-inhibiting capacity, a possible involvement of melatonin in electromagnetic field effects on cancer, and the oncotherapeutic potential of melatonin are also addressed. The encouraging results should incite further research to elucidate the exact nature of the link between the pineal gland and cancer for the benefit of patients.


Melatonin

Melatonin

Author: Hing-Sing Yu

Publisher: CRC Press

Published: 2020-10-28

Total Pages: 561

ISBN-13: 1000098834

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Melatonin: Biosynthesis, Physiological Effects, and Clinical Applications provides a thorough review of recent advances in major areas of melatonin research. The book is arranged in a logical sequence, beginning with the history of melatonin and then proceeding to cover its biochemistry and secretion, physiological effects, and clinical significance. New findings and current concepts are emphasized, and a significant amount of previously unpublished data are included. The book will be an important reference for neurobiologists, cell biologists, ophthalmologists, endocrinologists, neuroendocrinologists, reproductive biologists, psychiatrists, and other researchers and clinicians interested in melatonin.


Seasonal Affective Disorder

Seasonal Affective Disorder

Author: Timo Partonen

Publisher: Oxford University Press

Published: 2010

Total Pages: 370

ISBN-13: 019954428X

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Seasonal affective disorder (SAD), or winter depression, is a mood disorder related to the change in the seasons and lack of exposure to daylight. It affects 1 in 100 adults in western countries. SAD is a rare example of a psychiatric disorder with a clear, identifiable biological cause. The new edition of this award winning book brings together distinguished scientists and opinion leaders to discuss the current and anticipated developments in the study and care of Seasonal Affective Disorder. Highlighting the clinical diagnosis and management of Seasonal Affective Disorder (SAD), this book provides a valuable resource for all whom are involved in the health care for patients with SAD. This book deals with the range of therapeutic measures that are available for the treatment of SAD. In addition, this book elucidates potential areas of research that have emerged such as the study of the circadian pacemaker and the night-time sleep structure and their interaction that influences mood.


Synthesis of Best-Seller Drugs

Synthesis of Best-Seller Drugs

Author: Ruben Vardanyan

Publisher: Academic Press

Published: 2016-01-07

Total Pages: 870

ISBN-13: 0124115241

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Synthesis of Best-Seller Drugs is a key reference guide for all those involved with the design, development, and use of the best-selling drugs. Designed for ease of use, this book provides detailed information on the most popular drugs, using a practical layout arranged according to drug type. Each chapter reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and synthesis. Of high interest to all those who work in the captivating areas of biologically active compounds and medicinal drug synthesis, in particular medicinal chemists, biochemists, and pharmacologists, the book aims to support current research efforts, while also encouraging future developments in this important field. - Describes methods of synthesis, bioactivity and related drugs in key therapeutic areas - Reviews the main drugs in each of nearly 40 key therapeutic areas, also examining their classification, novel structural features, models of action, and more - Presents a practical layout designed for use as a quick reference tool by those working in drug design, development and implementation


Circadian Rhythm Sleep-Wake Disorders

Circadian Rhythm Sleep-Wake Disorders

Author: R. Robert Auger

Publisher: Springer Nature

Published: 2020-05-26

Total Pages: 251

ISBN-13: 3030438031

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This book resolves to bridge the communication gap between research and clinical practice for circadian rhythm sleep-wake disorders. Beginning with a scientific background on biological timekeeping, opening chapters describe the crucial nature of maintaining delicate temporal organization of physiological and molecular events within the body. Following this are discussions on circadian physiology and methods of circadian assessments. Subsequent chapters then relay comprehensive information regarding the International Classification of Sleep Disorders-defined circadian rhythm sleep-wake disorders (CRSWDs), specifically discussing etiology and epidemiology, but focusing on evidence-based treatment data. Concluding discussions provide guidance for the application of light therapy and discuss future roles for optimized lighting environments. Nuanced and market-demanded, Circadian Rhythm Sleep-Wake Disorders: An Evidence-Based Guide for Clinicians and Investigators is an invaluable resource for Sleep Medicine clinicians, circadian researchers, and other interested parties.


Rhythms in Fishes

Rhythms in Fishes

Author: Mohamed Ather Ali

Publisher: Springer Science & Business Media

Published: 1992

Total Pages: 370

ISBN-13: 9780306443183

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Addressed primarily to researchers of fish, but also of possible interest to researchers of biological rhythms in general, 19 papers from a workshop near Montreal, August 1991, discuss aspects of the biorhythms of fishes as they apply to aquaculture and to reactions to the pollution of natural habit