Neurotoxicology

Neurotoxicology

Author: Louis W. Chang

Publisher: Elsevier

Published: 1995-04-20

Total Pages: 875

ISBN-13: 0080537472

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Neurotoxicology: Approaches and Methods provides a unique and comprehensive presentation of the current concepts and state-of-the-art methods for the assessment of neurotoxicity. The book analyzes various techniques available and discusses their strengths and weaknesses. This volume will serve as an excellent desk companion and laboratory guide for all investigators, researchers, clinicians, and students interested in neurotoxicology. The internationally knowngroup of editors divide the book into seven sections: Neuromorphological and Neuropathological Approaches; Neurophysiological Approaches; Neurobehavioral Toxicology; Neurochemical and Biomolecular Approaches; In-Vitro Models; Clinical Neurotoxicology; and Risk Assessment of Neurotoxicity. Each section yields the most up-to-date information by experts in their fields. Meticulously organized and edited, Neurotoxicology: Approaches and Methods is the most authoritative and well-planned neurotoxicology book on the market. - Discusses neurobehavioral testing methods for assessment of neural dysfunctions - Explains state-of-the-art diagnostic methods, such as clinico-neuropsychological and neurophysiological methods, for patients confronted by neurotoxic problems - Discusses In Vitro methods, including aggregating brain cell methods, organotypic cultures, and the use of human neuronal cell lines for the assessment of neurotoxicity - Presents step-by-step procedures for many methods - Provides state-of-the-art neuromorphological and biomolecular methods and approaches for neurotoxicity investigation


Environmental Neurotoxicology

Environmental Neurotoxicology

Author: National Research Council

Publisher: National Academies Press

Published: 1992-02-01

Total Pages: 167

ISBN-13: 0309045312

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Scientists agree that exposure to toxic agents in the environment can cause neurological and psychiatric illnesses ranging from headaches and depression to syndromes resembling parkinsonism. It can even result in death at high exposure levels. The emergence of subclinical neurotoxicity-the concept that long-term impairments can escape clinical detection-makes the need for risk assessment even more critical. This volume paves the way toward definitive solutions, presenting the current consensus on risk assessment and environmental toxicants and offering specific recommendations. The book covers: The biologic basis of neurotoxicity. Progress in the application of biologic markers. Reviews of a wide range of in vitro and in vivo testing techniques. The use of surveillance and epidemiology to identify neurotoxic hazards that escape premarket screening. Research needs. This volume will be an important resource for policymakers, health specialists, researchers, and students.


Clinical Neurotoxicology E-Book

Clinical Neurotoxicology E-Book

Author: Michael R. Dobbs

Publisher: Elsevier Health Sciences

Published: 2009-07-22

Total Pages: 729

ISBN-13: 032307099X

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Clinical Neurotoxicology offers accurate, relevant, and comprehensive coverage of a field that has grown tremendously in the last 20 years. You’ll get a current symptomatic approach to treating disorders caused by neurotoxic agents, environmental factors—such as heavy metals and pesticides—and more. Apply discussions of cellular and molecular processes and pathology to clinical neurology. Leading authorities and up-and-coming clinical neurotoxicologists present their expertise on wide-ranging, global subjects and debate controversies in the specialty, including Gulf War Syndrome. Provides a complete listing of neurotoxic agents—from manufactured to environmental—so you get comprehensive, clinical coverage. Covers how toxins manifest themselves according to age and co-morbidity so that you can address the needs of all your patients. Offers broad and in-depth coverage of toxins from all over the world through contributions by leading authorities and up-and-coming clinical neurotoxicologists. Features discussion of controversial and unusual topics such as Gulf War Syndrome, Parkinson’s Disease, motor neuron disease, as well as other issues that are still in question.


Clinical Neurotoxicology

Clinical Neurotoxicology

Author: Michael R. Dobbs

Publisher: Elsevier Health Sciences

Published: 2009-01-01

Total Pages: 729

ISBN-13: 0323052606

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Clinical Neurotoxicology offers accurate, relevant, and comprehensive coverage of a field that has grown tremendously in the last 20 years. You'll get a current symptomatic approach to treating disorders caused by neurotoxic agents, environmental factors-such as heavy metals and pesticides-and more. Apply discussions of cellular and molecular processes and pathology to clinical neurology. Leading authorities and up-and-coming clinical neurotoxicologists present their expertise on wide-ranging, global subjects and debate controversies in the specialty, including Gulf War Syndrome. And, Expert Consult functionality allows you to access the full text of the book online, from any Internet connection. Provides a complete listing of neurotoxic agents-from manufactured to environmental-so you get comprehensive, clinical coverage. Covers how toxins manifest themselves according to age and co-morbidity so that you can address the needs of all your patients. Offers broad and in-depth coverage of toxins from all over the world through contributions by leading authorities and up-and-coming clinical neurotoxicologists. Features discussion of controversial and unusual topics such as Gulf War Syndrome, Parkinson's Disease, motor neuron disease, as well as other issues that are still in question. Includes access to www.expertconsult.com, a companion website where you can quickly search the complete contents of the book. Your purchase entitles you to access the web site until the next edition is published, or until the current edition is no longer offered for sale by Elsevier, whichever occurs first. If the next edition is published less than one year after your purchase, you will be entitled to online access for one year from your date of purchase. Elsevier reserves the right to offer a suitable replacement product (such as a downloadable or CD-ROM-based electronic version) should online access to the web site be discontinued.


Medical Toxicology

Medical Toxicology

Author: Richard C. Dart

Publisher: Lippincott Williams & Wilkins

Published: 2004

Total Pages: 1990

ISBN-13: 9780781728454

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This thoroughly revised and updated Third Edition of the classic Medical Toxicology is the definitive reference on the management of poisoned patients. More than 300 well-organized chapters written by eminent authorities guide clinicians through the diagnosis and treatment of every poisoning or drug overdose. Chapter outlines, headings, and a detailed index enable readers to quickly locate exactly the information they need. This edition includes new chapters on biological and chemical weapons and on diagnosis of patients with apparent symptoms of poisoning when the cause is unknown. The book includes comparative commentary on toxicology practice in the United States, Europe, Australia, and Asia. Compatibility: BlackBerry® OS 4.1 or Higher / iPhone/iPod Touch 2.0 or Higher /Palm OS 3.5 or higher / Palm Pre Classic / Symbian S60, 3rd edition (Nokia) / Windows Mobile™ Pocket PC (all versions) / Windows Mobile Smartphone / Windows 98SE/2000/ME/XP/Vista/Tablet PC


Handbook of Neurotoxicology

Handbook of Neurotoxicology

Author: Edward J. Massaro

Publisher: Springer Science & Business Media

Published: 2001-11-12

Total Pages: 658

ISBN-13: 1592591329

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Neurotoxicology is a broad and burgeoning field of research. Its growth in recent years can be related, in part, to increased interest in and concern with the fact that a growing number of anthropogenic agents with neurotoxic potential, including pesticides, lead, mercury, and the polytypic bypro ducts of combustion and industrial production, continue to be spewed into and accumulate in the environment. In addition, there is great interest in natural products, including toxins, as sources of therapeutic agents. Indeed, it is well known that many natural toxins of broadly differing structure, produced or accumulated for predatory or defensive purposes, and toxic agents, accumulated incidentally by numerous species, function to perturb nervous tissue. Components of some of these toxins have been shown to be useful therapeutic agents and/or research reagents. Unfor tunately, the environmental accumulation of some neurotoxic ants of anthropogenic ori gin, especially pesticides and metals, has resulted in incidents of human poisoning, some of epidemic proportion, and high levels of morbidity and mortality. Furthermore, an increasing incidence of neurobehavioral disorders, some with baffling symptoms, is confronting clinicians. It is not clear whether this is merely the result of increased vigi lance and/or improved diagnostics or a consequence of improved health care. In any case, the role of exposure to environmental and occupational neurotoxic ants in the etiology of these phenomena, as well as neurodegenerative diseases, is coming under increasing scrutiny and investigation.


Neurotoxicology

Neurotoxicology

Author: Mohamed B. Abou-Donia

Publisher: CRC Press

Published: 1992-07-15

Total Pages: 640

ISBN-13: 9781439805428

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Neurotoxicology provides a thorough understanding of neurotoxicology through its integration of multilateral ideas covering several disciplines, including chemistry, biochemistry, anatomy, physiology, and pathology. It discusses neurotoxic agents, describes the methods for studying neurotoxic actions, covers factors affecting neurotoxicity, and inc


Occupational Neurotoxicology

Occupational Neurotoxicology

Author: Lucio G. Costa

Publisher: CRC Press

Published: 2020-04-14

Total Pages: 329

ISBN-13: 1000083292

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First published in 1988, many chemical compounds present in workplace settings can produce a number of impairments in the human nervous system. As the situations in which neurotoxic agents have been recognized in exposed workers has grown, so has the importance of occupational neurotoxicology as a specialty. Addressing some of the most vital concerns in the field, Occupational Neurotoxicology discusses: Neurotoxic agents commonly encountered in the workplace Signs and symptoms of neurotoxicity and of the factors affecting neurotoxic effects Biological monitoring and the use of biomarkers Epidemiological methods and clinical approaches to occupational neurotoxicology The analysis of behavioral, electrophysiological, and imaging techniques in the diagnosis of neurotoxicity Occupational neurotoxicity in developing countries The evaluation and management of occupational illnesses due to neurotoxicity Occupational Neurotoxicology concisely covers important facts on the adverse effects of chemical, biological, and physical agents that can impair or alter the structure of the nervous system. Professionals and researchers in the fields of occupational medicine, toxicology, epidemiology, neurology, industrial hygiene, and psychology will all find relevant information on the health problems that can occur from exposure to neurotoxicants.


Biocompatibility and Performance of Medical Devices

Biocompatibility and Performance of Medical Devices

Author: Jean-Pierre Boutrand

Publisher: Woodhead Publishing

Published: 2019-11-21

Total Pages: 592

ISBN-13: 0081026447

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Biocompatibility and Performance of Medical Devices, Second Edition, provides an understanding of the biocompatibility and performance tests for ensuring that biomaterials and medical devices are safe and will perform as expected in the biological environment. Sections cover key concepts and challenges faced in relation to biocompatibility in medical devices, discuss the evaluation and characterization of biocompatibility in medical devices, describe preclinical performance studies for bone, dental and soft tissue implants, and provide information on the regulation of medical devices in the European Union, Japan and China. The book concludes with a review of histopathology principles for biocompatibility and performance studies. - Presents diverse insights from experts in government, industry and academia - Delivers a comprehensive overview of testing and interpreting medical device performance - Expanded to include new information, including sections on managing extractables, accelerating and simplifying medical device development through screening and alternative biocompatibility methods, and quality strategies which fasten device access to market


Handbook of Developmental Neurotoxicology

Handbook of Developmental Neurotoxicology

Author: William Slikker Jr.

Publisher: Elsevier

Published: 1998-08-10

Total Pages: 767

ISBN-13: 0080533434

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The Handbook of Developmental Neurotoxicology provides a comprehensive account of the impacts, mechanisms, and clinical relevances of chemicals on the development of the nervous system. The book is written by internationally recognized experts on developmental neurotoxicology, covering subjects from basic neuro-development to toxic syndromes induced by various chemicals. It is an important text for both students and professionals who are interested in developmental neurobiology and neurotoxicology. - Written by internationally recognized experts on developmental neurotoxicology - Includes extensive references - Well illustrated with diagrams, charts and tables - Provides coverage of basic neurobiology as well as neurotoxicology