Mathematical Models for Therapeutic Approaches to Control HIV Disease Transmission
Mathematical Models for Therapeutic Approaches to Control HIV Disease Transmission

Author: Priti Kumar Roy

Publisher: Springer

Published: 2015-12-08

Total Pages: 228

ISBN-13: 9812878521

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The book discusses different therapeutic approaches based on different mathematical models to control the HIV/AIDS disease transmission. It uses clinical data, collected from different cited sources, to formulate the deterministic as well as stochastic mathematical models of HIV/AIDS. It provides complementary approaches, from deterministic and stochastic points of view, to optimal control strategy with perfect drug adherence and also tries to seek viewpoints of the same issue from different angles with various mathematical models to computer simulations. The book presents essential methods and techniques for students who are interested in designing epidemiological models on HIV/AIDS. It also guides research scientists, working in the periphery of mathematical modeling, and helps them to explore a hypothetical method by examining its consequences in the form of a mathematical modelling and making some scientific predictions. The model equations, mathematical analysis and several numerical simulations that are presented in the book would serve to reveal the consequences of the logical structure of the disease transmission, quantitatively as well as qualitatively. One of the chapters introduces the optimal control approach towards the mathematical models, describing the optimal drug dosage process that is discussed with the basic deterministic models dealing with stability analysis. Another one chapter deals with the mathematical analysis for the perfect drug adherence for different drug dynamics during the treatment management. The last chapter of the book consists the stochastic approach to the disease dynamics on HIV/AIDS. This method helps to move the disease HIV/AIDS to extinction as the time to increase. This book will appeal to undergraduate and postgraduate students, as well as researchers, who are studying and working in the field of bio-mathematical modelling on infectious diseases, applied mathematics, health informatics, applied statistics and qualitative public health, etc. Social workers, who are working in the field of HIV, will also find the book useful for complements.

Disease Control Priorities, Third Edition (Volume 6)
Disease Control Priorities, Third Edition (Volume 6)

Author: King K. Holmes

Publisher: World Bank Publications

Published: 2017-11-06

Total Pages: 1027

ISBN-13: 1464805253

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Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.

Mathematical Epidemiology
Mathematical Epidemiology

Author: Fred Brauer

Publisher: Springer Science & Business Media

Published: 2008-04-30

Total Pages: 415

ISBN-13: 3540789103

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Based on lecture notes of two summer schools with a mixed audience from mathematical sciences, epidemiology and public health, this volume offers a comprehensive introduction to basic ideas and techniques in modeling infectious diseases, for the comparison of strategies to plan for an anticipated epidemic or pandemic, and to deal with a disease outbreak in real time. It covers detailed case studies for diseases including pandemic influenza, West Nile virus, and childhood diseases. Models for other diseases including Severe Acute Respiratory Syndrome, fox rabies, and sexually transmitted infections are included as applications. Its chapters are coherent and complementary independent units. In order to accustom students to look at the current literature and to experience different perspectives, no attempt has been made to achieve united writing style or unified notation. Notes on some mathematical background (calculus, matrix algebra, differential equations, and probability) have been prepared and may be downloaded at the web site of the Centre for Disease Modeling (www.cdm.yorku.ca).

Mathematical Models for Therapeutic Approaches to Control Psoriasis
Mathematical Models for Therapeutic Approaches to Control Psoriasis

Author: Priti Kumar Roy

Publisher: Springer

Published: 2019-07-18

Total Pages: 100

ISBN-13: 9811390207

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This book discusses several mathematical models highlighting the disease dynamics of psoriasis and its control. It explains the control of keratinocyte concentration through a negative feedback mechanism and the effect of including a realistic time delay in that system. The effect of cytokine release is described in a mathematical model of psoriasis and further elucidated in two different mathematical pathways: the ordinary differential equation model system, and the fractional-order differential equation model system. The book also identifies the role of CD8+ T-cells in psoriasis by investigating the interaction between dendritic cells and CD8+ T-cells. Presenting an approach to control the fractional-order system to prevent excess production of keratinocyte cell population, the book is intended for researchers and scientists in the field of applied mathematics, health informatics, applied statistics and qualitative public health, as well as bio-mathematicians interested in the mathematical modeling of autoimmune diseases like psoriasis.

Modern Infectious Disease Epidemiology
Modern Infectious Disease Epidemiology

Author: Alexander Krämer

Publisher: Springer Science & Business Media

Published: 2010-01-23

Total Pages: 441

ISBN-13: 0387938354

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Hardly a day goes by without news headlines concerning infectious disease threats. Currently the spectre of a pandemic of influenza A|H1N1 is raising its head, and heated debates are taking place about the pro’s and con’s of vaccinating young girls against human papilloma virus. For an evidence-based and responsible communication of infectious disease topics to avoid misunderstandings and overreaction of the public, we need solid scientific knowledge and an understanding of all aspects of infectious diseases and their control. The aim of our book is to present the reader with the general picture and the main ideas of the subject. The book introduces the reader to methodological aspects of epidemiology that are specific for infectious diseases and provides insight into the epidemiology of some classes of infectious diseases characterized by their main modes of transmission. This choice of topics bridges the gap between scientific research on the clinical, biological, mathematical, social and economic aspects of infectious diseases and their applications in public health. The book will help the reader to understand the impact of infectious diseases on modern society and the instruments that policy makers have at their disposal to deal with these challenges. It is written for students of the health sciences, both of curative medicine and public health, and for experts that are active in these and related domains, and it may be of interest for the educated layman since the technical level is kept relatively low.

Mathematical Epidemiology of Infectious Diseases
Mathematical Epidemiology of Infectious Diseases

Author: O. Diekmann

Publisher: John Wiley & Sons

Published: 2000-04-07

Total Pages: 324

ISBN-13: 9780471492412

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Mathematical Epidemiology of Infectious Diseases Model Building, Analysis and Interpretation O. Diekmann University of Utrecht, The Netherlands J. A. P. Heesterbeek Centre for Biometry Wageningen, The Netherlands The mathematical modelling of epidemics in populations is a vast and important area of study. It is about translating biological assumptions into mathematics, about mathematical analysis aided by interpretation and about obtaining insight into epidemic phenomena when translating mathematical results back into population biology. Model assumptions are formulated in terms of, usually stochastic, behaviour of individuals and then the resulting phenomena, at the population level, are unravelled. Conceptual clarity is attained, assumptions are stated clearly, hidden working hypotheses are attained and mechanistic links between different observables are exposed. Features: * Model construction, analysis and interpretation receive detailed attention * Uniquely covers both deterministic and stochastic viewpoints * Examples of applications given throughout * Extensive coverage of the latest research into the mathematical modelling of epidemics of infectious diseases * Provides a solid foundation of modelling skills The reader will learn to translate, model, analyse and interpret, with the help of the numerous exercises. In literally working through this text, the reader acquires modelling skills that are also valuable outside of epidemiology, certainly within population dynamics, but even beyond that. In addition, the reader receives training in mathematical argumentation. The text is aimed at applied mathematicians with an interest in population biology and epidemiology, at theoretical biologists and epidemiologists. Previous exposure to epidemic concepts is not required, as all background information is given. The book is primarily aimed at self-study and ideally suited for small discussion groups, or for use as a course text.

The Social Impact of AIDS in the United States
The Social Impact of AIDS in the United States

Author: National Research Council

Publisher: National Academies Press

Published: 1993-02-01

Total Pages: 337

ISBN-13: 0309046289

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Europe's "Black Death" contributed to the rise of nation states, mercantile economies, and even the Reformation. Will the AIDS epidemic have similar dramatic effects on the social and political landscape of the twenty-first century? This readable volume looks at the impact of AIDS since its emergence and suggests its effects in the next decade, when a million or more Americans will likely die of the disease. The Social Impact of AIDS in the United States addresses some of the most sensitive and controversial issues in the public debate over AIDS. This landmark book explores how AIDS has affected fundamental policies and practices in our major institutions, examining: How America's major religious organizations have dealt with sometimes conflicting values: the imperative of care for the sick versus traditional views of homosexuality and drug use. Hotly debated public health measures, such as HIV antibody testing and screening, tracing of sexual contacts, and quarantine. The potential risk of HIV infection to and from health care workers. How AIDS activists have brought about major change in the way new drugs are brought to the marketplace. The impact of AIDS on community-based organizations, from volunteers caring for individuals to the highly political ACT-UP organization. Coping with HIV infection in prisons. Two case studies shed light on HIV and the family relationship. One reports on some efforts to gain legal recognition for nonmarital relationships, and the other examines foster care programs for newborns with the HIV virus. A case study of New York City details how selected institutions interact to give what may be a picture of AIDS in the future. This clear and comprehensive presentation will be of interest to anyone concerned about AIDS and its impact on the country: health professionals, sociologists, psychologists, advocates for at-risk populations, and interested individuals.

Industrial Engineering in the Digital Disruption Era
Industrial Engineering in the Digital Disruption Era

Author: Fethi Calisir

Publisher: Springer Nature

Published: 2020-03-16

Total Pages: 382

ISBN-13: 3030424162

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This book gathers extended versions of the best papers presented at the Global Joint Conference on Industrial Engineering and Its Application Areas (GJCIE), held on September 2–3, 2019, in Gazimagusa, North Cyprus, Turkey. It covers a wide range of topics, including decision analysis, supply chain management, systems modelling and quality control. Further, special emphasis is placed on the state of the art and the challenges of digital disruption, as well as effective strategies that can be used to change organizational structures and eliminate the barriers that are keeping industries from taking full advantage of today’s digital technologies.

Confronting AIDS
Confronting AIDS

Author: World Bank

Publisher: World Bank Publications

Published: 1999

Total Pages: 396

ISBN-13: 9780195215915

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This revised and updated edition of the pathbreaking report on the global AIDS epidemic outlines the strategic role that government must play in slowing the spread of HIV and mitigating the impact of AIDS. Drawing on the knowledge accumulated in the 17 years since the virus that causes AIDS was first identified, the report highlights policies that are most likely to be effective in managing the epidemic. These include early actions to minimize the spread of the virus, aiming preventive interventions at high risk groups, and evaluating measures that would assist households affected by AIDS according to the same standards applied to other health issues. This revised edition will a valuable resource for public health, policymakers, researchers, and anyone with an interest in this devastating global health crisis.