The book covers important topics in the psychiatric genetics (PG) field. Many of these have been overlooked in mainstream accounts, and many contemporary PG researchers have omitted or whitewashed the eugenic and “racial hygiene” origins of the field. The author critically analyzes PG evidence in support of genetic claims which, given the lack of gene discoveries, are based mainly on the results of psychiatric twin and adoption studies. Given that the evidence in favor of genetic influences is much weaker than mainstream sources report, due to serious issues in twin and adoption research, the author points to environmental factors, including trauma, as the main causes of conditions such as schizophrenia.
Are hallucinations and delusions really symptoms of an illness called ‘schizophrenia’? Are mental health problems really caused by chemical imbalances and genetic predispositions? Are psychiatric drugs as effective and safe as the drug companies claim? Is madness preventable? This second edition of Models of Madness challenges those who hold to simplistic, pessimistic and often damaging theories and treatments of madness. In particular it challenges beliefs that madness can be explained without reference to social causes and challenges the excessive preoccupation with chemical imbalances and genetic predispositions as causes of human misery, including the conditions that are given the name 'schizophrenia'. This edition updates the now extensive body of research showing that hallucinations, delusions etc. are best understood as reactions to adverse life events and that psychological and social approaches to helping are more effective and far safer than psychiatric drugs and electroshock treatment. A new final chapter discusses why such a damaging ideology has come to dominate mental health and, most importantly, how to change that. Models of Madness is divided into three sections: Section One provides a history of madness, including examples of violence against the ‘mentally ill’, before critiquing the theories and treatments of contemporary biological psychiatry and documenting the corrupting influence of drug companies. Section Two summarises the research showing that hallucinations, delusions etc. are primarily caused by adverse life events (eg. parental loss, bullying, abuse and neglect in childhood, poverty, etc) and can be understood using psychological models ranging from cognitive to psychodynamic. Section Three presents the evidence for a range of effective psychological and social approaches to treatment, from cognitive and family therapy to primary prevention. This book brings together thirty-seven contributors from ten countries and a wide range of scientific disciplines. It provides an evidence-based, optimistic antidote to the pessimism of biological psychiatry. Models of Madness will be essential reading for all involved in mental health, including service users, family members, service managers, policy makers, nurses, clinical psychologists, psychiatrists, psychotherapists, counsellors, psychoanalysts, social workers, occupational therapists, art therapists.
In assuming that mental illness is a mathematical problem, The Logic of Madness analyses how a human action can be deviant even when rational. It reveals that a person without a genetic or brain abnormality can have an apparent mental disorder that is entirely logical in its structure.
Models of Madnessshows that hallucinations and delusions are understandable reactions to life events and circumstances rather than symptoms of a supposed genetic predisposition or biological disturbance. International contributors: * critique the 'medical model' of madness * examine the dominance of the 'illness' approach to understanding madness from historical and economic perspectives * document the role of drug companies * outline the alternative to drug based solutions * identify the urgency and possibility of prevention of madness. Models of Madness promotes a more humane and effective response to treating severely distressed people that will prove essential reading for psychiatrists and clinical psychologists and of great interest to all those who work in the mental health service. This book forms part of the International Society for the Psychological Treatment of Psychoses series edited by Brian Martindale.
Celebrated scientists Nicholas Christakis and James Fowler explain the amazing power of social networks and our profound influence on one another's lives. Your colleague's husband's sister can make you fat, even if you don't know her. A happy neighbor has more impact on your happiness than a happy spouse. These startling revelations of how much we truly influence one another are revealed in the studies of Dr. Christakis and Fowler, which have repeatedly made front-page news nationwide. In Connected, the authors explain why emotions are contagious, how health behaviors spread, why the rich get richer, even how we find and choose our partners. Intriguing and entertaining, Connected overturns the notion of the individual and provides a revolutionary paradigm-that social networks influence our ideas, emotions, health, relationships, behavior, politics, and much more. It will change the way we think about every aspect of our lives.
For laypeople and professionals alike who yearn for a better understanding of genetically engineered crops, DNA fingerprinting, cloning, or gene therapy, here is a valuable addition to a small but critical literature that will frame the public discourse as it is decided how to use the burgeoning knowledge of the genome. The lessons are delivered in the course of fascinating historical tales (including an especially enjoyable chapter on Henri de Toulouse-Lautrec) with a hint of Lewis Thomas-like awe and fascination with the power of genetic analysis.
Roddy Dolan, a successful suburban surgeon, long ago left behind his past--one that nearly landed him in jail at 17. When he's approached by an old friend about becoming a silent partner in a Manhattan steakhouse, he's understandably wary. So he consults with his lifelong blood brother, Danny Burns. Danny's convinced this "vanity project" is the perfect trophy to illustrate how far they've travelled. Certain he's buried his checkered past, Roddy joins in this venture with serious reservations. Danny is quickly sucked into the high-energy glitz of the restaurant, but Roddy is suspicious. Amidst the glitter of New York's nightlife, amongst Mafia honchos and Russian thugs, events spin out of control and the lives Roddy and Danny knew are over. Hidden shady dealings drag them and their families into life-threatening terrain. Struggling with a monster he thought he'd buried, Roddy must make momentous choices, and none are good. But he has a daring plan . . .
What makes us human? In recent decades, researchers have focused on innate tendencies and inherited traits as explanations for human behavior, especially in light of groundbreaking human genome research. The author thinks this trend is misleading. As he shows in great detail in this engaging, thought-provoking, and highly informative book, what makes our species unique is our marvelous ability to learn, which is an ability that no other primate possesses. In his exploration of human progress, the author reveals that the immensity of human learning has not been fully understood or examined. Evolution has endowed us with extremely versatile bodies and a brain comprised of one hundred billion neurons, which makes us especially suited for a wide range of sophisticated learning. Already in childhood, human beings begin learning complex repertoires—language, sports, value systems, music, science, rules of behavior, and many other aspects of culture. These repertoires build on one another in special ways, and our brains develop in response to the learning experiences we receive from those around us and from what we read and hear and see. When humans gather in society, the cumulative effect of building learning upon learning is enormous. The author presents a new way of understanding humanness—in the behavioral nature of the human body, in the unique human way of learning, in child development, in personality, and in abnormal behavior. With all this, and his years of basic and applied research, he develops a new theory of human evolution and a new vision of the human being. This book offers up a unified concept that not only provides new ways of understanding human behavior and solving human problems but also lays the foundations for opening new areas of science.
This book develops the theory of continuous and discrete stochastic processes within the context of cell biology. In the second edition the material has been significantly expanded, particularly within the context of nonequilibrium and self-organizing systems. Given the amount of additional material, the book has been divided into two volumes, with volume I mainly covering molecular processes and volume II focusing on cellular processes. A wide range of biological topics are covered in the new edition, including stochastic ion channels and excitable systems, molecular motors, stochastic gene networks, genetic switches and oscillators, epigenetics, normal and anomalous diffusion in complex cellular environments, stochastically-gated diffusion, active intracellular transport, signal transduction, cell sensing, bacterial chemotaxis, intracellular pattern formation, cell polarization, cell mechanics, biological polymers and membranes, nuclear structure and dynamics, biological condensates, molecular aggregation and nucleation, cellular length control, cell mitosis, cell motility, cell adhesion, cytoneme-based morphogenesis, bacterial growth, and quorum sensing. The book also provides a pedagogical introduction to the theory of stochastic and nonequilibrium processes – Fokker Planck equations, stochastic differential equations, stochastic calculus, master equations and jump Markov processes, birth-death processes, Poisson processes, first passage time problems, stochastic hybrid systems, queuing and renewal theory, narrow capture and escape, extreme statistics, search processes and stochastic resetting, exclusion processes, WKB methods, large deviation theory, path integrals, martingales and branching processes, numerical methods, linear response theory, phase separation, fluctuation-dissipation theorems, age-structured models, and statistical field theory. This text is primarily aimed at graduate students and researchers working in mathematical biology, statistical and biological physicists, and applied mathematicians interested in stochastic modeling. Applied probabilists should also find it of interest. It provides significant background material in applied mathematics and statistical physics, and introduces concepts in stochastic and nonequilibrium processes via motivating biological applications. The book is highly illustrated and contains a large number of examples and exercises that further develop the models and ideas in the body of the text. It is based on a course that the author has taught at the University of Utah for many years.
The activity of neurons in the brain is noisy in that the neuronal firing times are random for a given mean rate. The Noisy Brain shows that this is fundamental to understanding many aspects of brain function, including probabilistic decision-making, perception, memory recall, short-term memory, attention, and even creativity. There are many applications too of this understanding, to for example memory and attentional disorders, aging, schizophrenia, and obsessive-compulsive disorder.
