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Author: John Rudolph Covach
Publisher: Oxford University Press, USA
Published: 1997
Total Pages: 238
ISBN-13: 0195100050
DOWNLOAD EBOOKEach of the essays in this serious study and analysis of rock music is written by one of musicology's best young scholars. The essays cover bands like The Grateful Dead, Yes, K.D. Lang, Jimi Hendrix and The Beach Boys.
Author: Jong Hoon Park
Publisher: Springer
Published: 2016-10-12
Total Pages: 128
ISBN-13: 9811020418
DOWNLOAD EBOOKAutosomal Dominant Polycystic Kidney Disease (ADPKD) is a highly prevalent hereditary renal disorder in which fluid-filled cysts are appeared in both kidneys. Main causative genes of ADPKD are PKD1 and PKD2, encoding for polycystin-1 (PC1) and polycystin-2 (PC2) respectively. Those proteins are localized on primary cilia and function as mechanosensor in response to the fluid flow, translating mechanistic stimuli into calcium signaling. With mutations either of PKD1 or PKD2, hyper-activated renal tubular epithelial cell proliferation is observed, followed by disrupted calcium homeostasis and aberrant intracellular cyclic AMP (cAMP) accumulation. Increased cell proliferation with fluid secretion leads to the development of thousands of epithelial-lined, fluid-filled cysts in kidneys. It is also accompanied by interstitial inflammation, fibrosis, and finally reaching end-stage renal disease (ESRD). In human ADPKD, the age at which renal failure typically occurs is later in life, however no specific targeted medications are available to cure ADPKD. Recently, potential therapeutic targets or surrogate diagnostic biomarkers for ADPKD are proposed with the advances in the understanding of ADPKD pathogenesis, and some of them were attempted for clinical trials. Herein, we will summarize genetic and epi-genetic molecular mechanisms in ADPKD progression, and overview the currently available biomarkers or potential therapeutic reagents suggested.
Author: National Science Foundation (U.S.)
Publisher:
Published: 1960
Total Pages: 32
ISBN-13:
DOWNLOAD EBOOKAuthor: Jacob A. Zumoff
Publisher: Rutgers University Press
Published: 2021-07-16
Total Pages: 178
ISBN-13: 1978809913
DOWNLOAD EBOOKThis book tells the story of 15,000 wool workers who went on strike for more than a year, defying police violence and hunger. The strikers were mainly immigrants and half were women. The Passaic textile strike, the first time that the Communist Party led a mass workers’ struggle in the United States, captured the nation’s imagination and came to symbolize the struggle of workers throughout the country when the labor movement as a whole was in decline during the conservative, pro-business 1920s. Although the strike was defeated, many of the methods and tactics of the Passaic strike presaged the struggles for industrial unions a decade later in the Great Depression.
Author: Nikolay Rimsky-Korsakov
Publisher: Carl Fischer, L.L.C.
Published: 2005
Total Pages: 128
ISBN-13: 9780825856990
DOWNLOAD EBOOKAuthor: United States. Congress. Senate. Select Committee on Small Business
Publisher:
Published: 1975
Total Pages: 1776
ISBN-13:
DOWNLOAD EBOOKAuthor: Lawrence E. Walsh
Publisher: Three Rivers Press
Published: 1994
Total Pages: 614
ISBN-13: 9780812924565
DOWNLOAD EBOOKAuthor: Susan Ronald
Publisher: St. Martin's Press
Published: 2021-08-03
Total Pages: 549
ISBN-13: 1250238730
DOWNLOAD EBOOKAcclaimed biographer Susan Ronald reveals the truth about Joseph P. Kennedy's deeply controversial tenure as Ambassador to Great Britain on the eve of World War II. On February 18, 1938, Joseph P. Kennedy was sworn in as US Ambassador to the Court of St. James. To say his appointment to the most prestigious and strategic diplomatic post in the world shocked the Establishment was an understatement: known for his profound Irish roots and staunch Catholicism, not to mention his “plain-spoken” opinions and womanizing, he was a curious choice as Europe hurtled toward war. Initially welcomed by the British, in less than two short years Kennedy was loathed by the White House, the State Department and the British Government. Believing firmly that Fascism was the inevitable wave of the future, he consistently misrepresented official US foreign policy internationally as well as direct instructions from FDR himself. The Americans were the first to disown him and the British and the Nazis used Kennedy to their own ends. Through meticulous research and many newly available sources, Ronald confirms in impressive detail what has long been believed by many: that Kennedy was a Fascist sympathizer and an anti-Semite whose only loyalty was to his family's advancement. She also reveals the ambitions of the Kennedy dynasty during this period abroad, as they sought to enter the world of high society London and establish themselves as America’s first family. Thorough and utterly readable, The Ambassador explores a darker side of the Kennedy patriarch in an account sure to generate attention and controversy.
Author: John E. Cooney
Publisher: Simon & Schuster
Published: 1982
Total Pages: 456
ISBN-13:
DOWNLOAD EBOOK"This is the colorful and dramatic biography of two of America's most controversial entrepreneurs: Moses Louis Annenberg, 'the racing wire king, ' who built his fortune in racketeering, invested it in publishing, and lost much of it in the biggest tax evasion case in United States history; and his son, Walter, launcher of TV Guide and Seventeen magazines and former ambassador to Great Britain."--Jacket.
Author: Sudhā Mūrti
Publisher: Penguin Books India
Published: 2006
Total Pages: 164
ISBN-13: 9780143330066
DOWNLOAD EBOOKA princess thinks she was a bird, a coconut that cost a thousand rupees, and a shepherd with a bag of words...Kings and misers, princes and paupers, wise men and foolish boys, the funniest and oddest men and women come alive in this sparkling new collection of stories. The clever princess will only marry the man who can ask her a question she cannot answer; the orphan boy outwits his greedy uncles with a bag of ash; and an old couple in distress is saved by a magic drum. Sudha Murty's grandparents told her some of these stories when she was a child; others she heard from her friends from around the world. These delightful and timeless folktales have been her favourites for years, and she has recounted them many times over to the young people in her life. With this collection, they will be enjoyed by many more readers, of all ages. Age group of target audience is 8+.
