Describes in general how scientists can use handwritten research notebooks as a tool to record their research in progress, and in particular the legal protocols for industrial scientists to handwrite their research in progress so they can establish priority of invention in case a patent suit arises.
Winner of the 2007 National Book Critics Circle Award for Criticism A New York Times Book Review Top Ten Book of the Year Time magazine Top Ten Nonfiction Book of 2007 Newsweek Favorite Books of 2007 A Washington Post Book World Best Book of 2007 In this sweeping and dramatic narrative, Alex Ross, music critic for The New Yorker, weaves together the histories of the twentieth century and its music, from Vienna before the First World War to Paris in the twenties; from Hitler's Germany and Stalin's Russia to downtown New York in the sixties and seventies up to the present. Taking readers into the labyrinth of modern style, Ross draws revelatory connections between the century's most influential composers and the wider culture. The Rest Is Noise is an astonishing history of the twentieth century as told through its music.
A singular fatality has ruled the destiny of nearly all the most famous of Leonardo da Vinci's works. Two of the three most important were never completed, obstacles having arisen during his life-time, which obliged him to leave them unfinished; namely the Sforza Monument and the Wall-painting of the Battle of Anghiari, while the third—the picture of the Last Supper at Milan—has suffered irremediable injury from decay and the repeated restorations to which it was recklessly subjected during the XVIIth and XVIIIth centuries. Nevertheless, no other picture of the Renaissance has become so wellknown and popular through copies of every description. Vasari says, and rightly, in his Life of Leonardo, "that he laboured much more by his word than in fact or by deed", and the biographer evidently had in his mind the numerous works in Manuscript which have been preserved to this day. To us, now, it seems almost inexplicable that these valuable and interesting original texts should have remained so long unpublished, and indeed forgotten. It is certain that during the XVIth and XVIIth centuries their exceptional value was highly appreciated. This is proved not merely by the prices which they commanded, but also by the exceptional interest which has been attached to the change of ownership of merely a few pages of Manuscript. That, notwithstanding this eagerness to possess the Manuscripts, their contents remained a mystery, can only be accounted for by the many and great difficulties attending the task of deciphering them. The handwriting is so peculiar that it requires considerable practice to read even a few detached phrases, much more to solve with any certainty the numerous difficulties of alternative readings, and to master the sense as a connected whole. Vasari observes with reference to Leonardos writing: "he wrote backwards, in rude characters, and with the left hand, so that any one who is not practised in reading them, cannot understand them". The aid of a mirror in reading reversed handwriting appears to me available only for a first experimental reading. Speaking from my own experience, the persistent use of it is too fatiguing and inconvenient to be practically advisable, considering the enormous mass of Manuscripts to be deciphered. And as, after all, Leonardo's handwriting runs backwards just as all Oriental character runs backwards—that is to say from right to left—the difficulty of reading direct from the writing is not insuperable. This obvious peculiarity in the writing is not, however, by any means the only obstacle in the way of mastering the text. Leonardo made use of an orthography peculiar to himself; he had a fashion of amalgamating several short words into one long one, or, again, he would quite arbitrarily divide a long word into two separate halves; added to this there is no punctuation whatever to regulate the division and construction of the sentences, nor are there any accents—and the reader may imagine that such difficulties were almost sufficient to make the task seem a desperate one to a beginner. It is therefore not surprising that the good intentions of some of Leonardo s most reverent admirers should have failed.
Inspired by “The Little Mermaid,” Coral explores what it means to be human in a world where humanity often seems lost. Coral has always been different, standing out from her mermaid sisters in a society where blending in is key. She fears she has been afflicted with the dreaded Disease said to be carried by humans: emotions. Her sister had the Disease, and Red Tide took her away. Will it come for Coral next? Above the sea, Brooke has nothing left to give. Depression and anxiety have left her feeling isolated. Forgotten. The only thing she can rely on is the numbness she finds within the cool and comforting ocean waves. If only she weren’t stuck at a new group-therapy home that promises a second chance at life. But what’s the point of living if her soul is destined to bleed? Merrick may be San Francisco’s golden boy, but he wants nothing more than to escape his controlling father. When his younger sister’s suicide attempt sends Merrick to his breaking point, escape becomes the only option. If he can find their mom, everything will be made right again—right? When their worlds collide, all three will do whatever it takes to survive. But what—and who—must they leave behind for life to finally begin? Praise for Coral: “This heart-wrenching tale will pull you under its spell.” —ANNIE SULLIVAN, author of A Touch of Gold and Tiger Queen “A beautiful reimagining.” —LAUREN MANSY, author of The Memory Thief “A breathless, powerful journey of the heart and mind.” —LINDSAY A. FRANKLIN, award-winning author of The Story Peddler A stand-alone, full-length Young Adult novel Trigger warning: suicide and depression
"Everything I love in a book."—Victoria Schwab, author of #1 New York Times bestseller This Savage Song “The kind of taut, atmospheric thriller that gets your heart racing and sets your imagination on fire. Sensational.”—Claire Legrand, New York Times-bestselling author of Furyborn Finalist for the Minnesota Book Award New York Times–bestselling author Jacqueline West captivates readers with a dark, hypnotic story about the cost of talent—and the evil that lurks just out of sight. Fans of Holly Black and Victoria Schwab will be mesmerized by this gorgeous, magnetic novel. High school senior Anders Thorson is unusually gifted. His band, Last Things, is legendary in their northern Minnesota hometown. With guitar skills that would amaze even if he weren’t only eighteen, Anders is the focus of head-turning admiration. And Thea Malcom, a newcomer to the insular town, is one of his admirers. Thea seems to turn up everywhere Anders goes: gigs at the local coffeehouse, guitar lessons, even in the woods near Anders’s home. When strange things start happening to Anders, blame immediately falls on Thea. But is she trying to hurt him? Or save him? Can he trust a girl who doesn’t seem to know the difference between dreams and reality? And how much are they both willing to sacrifice to get what they want? Told from Anders’s and Thea’s dual points of view, this exquisitely crafted novel is full of unexpected twists and is for fans of Holly Black’s The Darkest Part of the Forest and Melissa Albert’s The Hazel Wood.
#1 NEW YORK TIMES BESTSELLER • “The story of modern medicine and bioethics—and, indeed, race relations—is refracted beautifully, and movingly.”—Entertainment Weekly NOW A MAJOR MOTION PICTURE FROM HBO® STARRING OPRAH WINFREY AND ROSE BYRNE • ONE OF THE “MOST INFLUENTIAL” (CNN), “DEFINING” (LITHUB), AND “BEST” (THE PHILADELPHIA INQUIRER) BOOKS OF THE DECADE • ONE OF ESSENCE’S 50 MOST IMPACTFUL BLACK BOOKS OF THE PAST 50 YEARS • WINNER OF THE CHICAGO TRIBUNE HEARTLAND PRIZE FOR NONFICTION NAMED ONE OF THE BEST BOOKS OF THE YEAR BY The New York Times Book Review • Entertainment Weekly • O: The Oprah Magazine • NPR • Financial Times • New York • Independent (U.K.) • Times (U.K.) • Publishers Weekly • Library Journal • Kirkus Reviews • Booklist • Globe and Mail Her name was Henrietta Lacks, but scientists know her as HeLa. She was a poor Southern tobacco farmer who worked the same land as her slave ancestors, yet her cells—taken without her knowledge—became one of the most important tools in medicine: The first “immortal” human cells grown in culture, which are still alive today, though she has been dead for more than sixty years. HeLa cells were vital for developing the polio vaccine; uncovered secrets of cancer, viruses, and the atom bomb’s effects; helped lead to important advances like in vitro fertilization, cloning, and gene mapping; and have been bought and sold by the billions. Yet Henrietta Lacks remains virtually unknown, buried in an unmarked grave. Henrietta’s family did not learn of her “immortality” until more than twenty years after her death, when scientists investigating HeLa began using her husband and children in research without informed consent. And though the cells had launched a multimillion-dollar industry that sells human biological materials, her family never saw any of the profits. As Rebecca Skloot so brilliantly shows, the story of the Lacks family—past and present—is inextricably connected to the dark history of experimentation on African Americans, the birth of bioethics, and the legal battles over whether we control the stuff we are made of. Over the decade it took to uncover this story, Rebecca became enmeshed in the lives of the Lacks family—especially Henrietta’s daughter Deborah. Deborah was consumed with questions: Had scientists cloned her mother? Had they killed her to harvest her cells? And if her mother was so important to medicine, why couldn’t her children afford health insurance? Intimate in feeling, astonishing in scope, and impossible to put down, The Immortal Life of Henrietta Lacks captures the beauty and drama of scientific discovery, as well as its human consequences.
With contributions from Cheryl Strayed, Mark Cuban, Ta-Nahesi Coates, Melinda Gates, Joss Whedon, James Patterson, and many more -- this fascinating collection gives us a peek into 150 personal treasures and the secret histories behind them. All of us have that one object that holds deep meaning--something that speaks to our past, that carries a remarkable story. Bestselling author Bill Shapiro collected this sweeping range of stories--he talked to everyone from renowned writers to Shark Tank hosts, from blackjack dealers to teachers, truckers, and nuns, even a reformed counterfeiter--to reveal the often hidden, always surprising lives of objects.
#1 New York Times bestseller · Seven starred reviews · Boston Globe-Horn Book Award Honor Book “For all the struggle in this book, Thomas rarely misses a step as a writer. Thomas continues to hold up that mirror with grace and confidence. We are lucky to have her, and lucky to know a girl like Bri.”—The New York Times Book Review This digital edition contains a letter from the author, deleted scenes, a picture of the author as a teen rapper, an annotated playlist, Angie’s top 5 MCs, an annotated rap, illustrated quotes from the book, and an excerpt from Concrete Rose, Angie's return to Garden Heights. Sixteen-year-old Bri wants to be one of the greatest rappers of all time. Or at least win her first battle. As the daughter of an underground hip hop legend who died right before he hit big, Bri’s got massive shoes to fill. But it’s hard to get your come up when you’re labeled a hoodlum at school, and your fridge at home is empty after your mom loses her job. So Bri pours her anger and frustration into her first song, which goes viral . . . for all the wrong reasons. Bri soon finds herself at the center of a controversy, portrayed by the media as more menace than MC. But with an eviction notice staring her family down, Bri doesn’t just want to make it—she has to. Even if it means becoming the very thing the public has made her out to be. Insightful, unflinching, and full of heart, On the Come Up is an ode to hip hop from one of the most influential literary voices of a generation. It is the story of fighting for your dreams, even as the odds are stacked against you; and about how, especially for young black people, freedom of speech isn’t always free. Don't miss Concrete Rose, Angie Thomas's powerful prequel to her phenomenal bestseller, The Hate U Give!
Susan Orlean’s bestseller and New York Times Notable Book is “a sheer delight…as rich in insight and as varied as the treasures contained on the shelves in any local library” (USA TODAY)—a dazzling love letter to a beloved institution and an investigation into one of its greatest mysteries. “Everybody who loves books should check out The Library Book” (The Washington Post). On the morning of April 28, 1986, a fire alarm sounded in the Los Angeles Public Library. The fire was disastrous: it reached two thousand degrees and burned for more than seven hours. By the time it was extinguished, it had consumed four hundred thousand books and damaged seven hundred thousand more. Investigators descended on the scene, but more than thirty years later, the mystery remains: Did someone purposefully set fire to the library—and if so, who? Weaving her lifelong love of books and reading into an investigation of the fire, award-winning New Yorker reporter and New York Times bestselling author Susan Orlean delivers a “delightful…reflection on the past, present, and future of libraries in America” (New York magazine) that manages to tell the broader story of libraries and librarians in a way that has never been done before. In the “exquisitely written, consistently entertaining” (The New York Times) The Library Book, Orlean chronicles the LAPL fire and its aftermath to showcase the larger, crucial role that libraries play in our lives; delves into the evolution of libraries; brings each department of the library to vivid life; studies arson and attempts to burn a copy of a book herself; and reexamines the case of Harry Peak, the blond-haired actor long suspected of setting fire to the LAPL more than thirty years ago. “A book lover’s dream…an ambitiously researched, elegantly written book that serves as a portal into a place of history, drama, culture, and stories” (Star Tribune, Minneapolis), Susan Orlean’s thrilling journey through the stacks reveals how these beloved institutions provide much more than just books—and why they remain an essential part of the heart, mind, and soul of our country.
#1 NEW YORK TIMES BESTSELLER • NOW A MAJOR MOTION PICTURE • Look for special features inside. Join the Random House Reader’s Circle for author chats and more. In boyhood, Louis Zamperini was an incorrigible delinquent. As a teenager, he channeled his defiance into running, discovering a prodigious talent that had carried him to the Berlin Olympics. But when World War II began, the athlete became an airman, embarking on a journey that led to a doomed flight on a May afternoon in 1943. When his Army Air Forces bomber crashed into the Pacific Ocean, against all odds, Zamperini survived, adrift on a foundering life raft. Ahead of Zamperini lay thousands of miles of open ocean, leaping sharks, thirst and starvation, enemy aircraft, and, beyond, a trial even greater. Driven to the limits of endurance, Zamperini would answer desperation with ingenuity; suffering with hope, resolve, and humor; brutality with rebellion. His fate, whether triumph or tragedy, would be suspended on the fraying wire of his will. Appearing in paperback for the first time—with twenty arresting new photos and an extensive Q&A with the author—Unbroken is an unforgettable testament to the resilience of the human mind, body, and spirit, brought vividly to life by Seabiscuit author Laura Hillenbrand. Hailed as the top nonfiction book of the year by Time magazine • Winner of the Los Angeles Times Book Prize for biography and the Indies Choice Adult Nonfiction Book of the Year award “Extraordinarily moving . . . a powerfully drawn survival epic.”—The Wall Street Journal “[A] one-in-a-billion story . . . designed to wrench from self-respecting critics all the blurby adjectives we normally try to avoid: It is amazing, unforgettable, gripping, harrowing, chilling, and inspiring.”—New York “Staggering . . . mesmerizing . . . Hillenbrand’s writing is so ferociously cinematic, the events she describes so incredible, you don’t dare take your eyes off the page.”—People “A meticulous, soaring and beautifully written account of an extraordinary life.”—The Washington Post “Ambitious and powerful . . . a startling narrative and an inspirational book.”—The New York Times Book Review “Magnificent . . . incredible . . . [Hillenbrand] has crafted another masterful blend of sports, history and overcoming terrific odds; this is biography taken to the nth degree, a chronicle of a remarkable life lived through extraordinary times.”—The Dallas Morning News “An astonishing testament to the superhuman power of tenacity.”—Entertainment Weekly “A tale of triumph and redemption . . . astonishingly detailed.”—O: The Oprah Magazine “[A] masterfully told true story . . . nothing less than a marvel.”—Washingtonian “[Hillenbrand tells this] story with cool elegance but at a thrilling sprinter’s pace.”—Time “Hillenbrand [is] one of our best writers of narrative history. You don’t have to be a sports fan or a war-history buff to devour this book—you just have to love great storytelling.”—Rebecca Skloot, author of The Immortal Life of Henrietta Lacks