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Author: Frederick Pollack
Publisher:
Published: 2018
Total Pages: 0
ISBN-13: 9780995767577
DOWNLOAD EBOOKPoems about US life before and during the Trump presidency, with its alienation, violence, and political despair. In this dystopian landscape, the weak exist to be trodden and those who are trodden are weak.' It is a book about casual racism, sharp-suited Fascism and the complicity of liberals in the assault on equality and justice. Between the nar
Author: Alan S. Perelson
Publisher: CRC Press
Published: 2018-03-08
Total Pages: 328
ISBN-13: 042996742X
DOWNLOAD EBOOKThis book lays out a number of the general issues concerning the structure of rugged fitness landscapes and examines both the history and the current status of experimental work on somatic mutation and the maturation of the immune response.
Author: Niall Kirkwood
Publisher: Taylor & Francis
Published: 2003-09-02
Total Pages: 466
ISBN-13: 1134544073
DOWNLOAD EBOOK**This title was originally published in 2001. The version published in 2011 is a PB reprint of the original HB** Manufactured Sites focuses on the legacy of industrial production and pollutants on the contemporary landscape and their influence on new scientific research, innovative site technologies and progressive site design. It presents innovative environmental, engineering and design approaches along with ongoing research and built projects of international significance. Contributions range from innovative scientific engineering research from industry and federal agencies to contemporary international and regional professional reclamation and redevelopment projects such as the 2000 Olympic Games in Sydney, Australia and the A.G. Thyssen steelworks and blast furnace planning in Germany's Ruhr region.
Author: Wojciech H. Zurek
Publisher: CRC Press
Published: 2018-03-08
Total Pages: 396
ISBN-13: 0429982518
DOWNLOAD EBOOKThis book has emerged from a meeting held during the week of May 29 to June 2, 1989, at St. John’s College in Santa Fe under the auspices of the Santa Fe Institute. The (approximately 40) official participants as well as equally numerous “groupies” were enticed to Santa Fe by the above “manifesto.” The book—like the “Complexity, Entropy and the Physics of Information” meeting explores not only the connections between quantum and classical physics, information and its transfer, computation, and their significance for the formulation of physical theories, but it also considers the origins and evolution of the information-processing entities, their complexity, and the manner in which they analyze their perceptions to form models of the Universe. As a result, the contributions can be divided into distinct sections only with some difficulty. Indeed, I regard this degree of overlapping as a measure of the success of the meeting. It signifies consensus about the important questions and on the anticipated answers: they presumably lie somewhere in the “border territory,” where information, physics, complexity, quantum, and computation all meet.
Author: George P. Rédei
Publisher: Springer Science & Business Media
Published: 2008-04-25
Total Pages: 2139
ISBN-13: 1402067534
DOWNLOAD EBOOKThis new third edition updates a best-selling encyclopedia. It includes about 56% more words than the 1,392-page second edition of 2003. The number of illustrations increased to almost 2,000 and their quality has improved by design and four colors. It includes approximately 1,800 current databases and web servers. This encyclopedia covers the basics and the latest in genomics, proteomics, genetic engineering, small RNAs, transcription factories, chromosome territories, stem cells, genetic networks, epigenetics, prions, hereditary diseases, and patents. Similar integrated information is not available in textbooks or on the Internet.
Author: Stuart A. Kauffman
Publisher: Oxford University Press
Published: 1993-06-10
Total Pages: 958
ISBN-13: 0199826676
DOWNLOAD EBOOKStuart Kauffman here presents a brilliant new paradigm for evolutionary biology, one that extends the basic concepts of Darwinian evolution to accommodate recent findings and perspectives from the fields of biology, physics, chemistry and mathematics. The book drives to the heart of the exciting debate on the origins of life and maintenance of order in complex biological systems. It focuses on the concept of self-organization: the spontaneous emergence of order that is widely observed throughout nature Kauffman argues that self-organization plays an important role in the Darwinian process of natural selection. Yet until now no systematic effort has been made to incorporate the concept of self-organization into evolutionary theory. The construction requirements which permit complex systems to adapt are poorly understood, as is the extent to which selection itself can yield systems able to adapt more successfully. This book explores these themes. It shows how complex systems, contrary to expectations, can spontaneously exhibit stunning degrees of order, and how this order, in turn, is essential for understanding the emergence and development of life on Earth. Topics include the new biotechnology of applied molecular evolution, with its important implications for developing new drugs and vaccines; the balance between order and chaos observed in many naturally occurring systems; new insights concerning the predictive power of statistical mechanics in biology; and other major issues. Indeed, the approaches investigated here may prove to be the new center around which biological science itself will evolve. The work is written for all those interested in the cutting edge of research in the life sciences.
Author: W.H. Moos
Publisher: Springer Science & Business Media
Published: 1997-04-30
Total Pages: 376
ISBN-13: 0306469049
DOWNLOAD EBOOKCombinatorial chemistry and molecular diversity approaches to scientific inquiry and novel product R&D have exploded in the 1990s! For example, in the preparation of drug candidates, the automated, permutational, and combinatorial use of chemical building blocks now allows the generation and screening of unprecedented numbers of compounds. Drug discovery - better, faster, cheaper? Indeed, more compounds have been made and screened in the 1990s than in the last hundred years of pharmaceutical research. This first volume covers: (i) combinatorial chemistry, (ii) combinatorial biology and evolution, and (iii) informatics and related topics. Within each section chapters are prepared by experts in the field, including, for example, in Section I: Coverage of mixture pools vs. parallel individual compound synthesis, solution vs. solid-phase synthesis, analytical tools, and automation. Section II highlights selection strategies and library-based evolution, phage display, peptide and nucleic acid libraries. Section III covers databases and library design, high through-put screening, coding strategies vs. deconvolutions, intellectual property issues, deals and collaborations, and successes to date.
Author: Francisco J. Varela
Publisher: Springer Science & Business Media
Published: 2013-03-09
Total Pages: 327
ISBN-13: 9401580545
DOWNLOAD EBOOKThe main intention of this book is to bring together contributions from biology, cognitive science, and the humanities for a joint exploration of some of the main contemporary notions dealing with the understanding of origins in life,mind and society. The question of origin is inseparable from a web of hypotheses that both shape and explain us. Although origin invites examination, it always seems to elude our grasp. Notions have always been produced to interpret the genesis of life, mind, and the social order, and these notions have all remained unstable in the face of theoretical and empirical challenges. In any given period, the central ideas on origin have had a mutual resonance frequently overlooked by specialists engaged in theirown particular fields. As a consequence, this book should be of interest to a wide audi ence. In particular, for all those engaged in the social sciences and the philosophy of science, it is unique document, since bridges to the natural sciences in a mutually illuminating way are hard to find. Whether as a primary source or as inspirational reading, we feel this book has a place in every library. The material comes from an international meeting held in September 13-16, 1987 at Stanford University, organized by F. Varela and J.-P. Dupuy at the request of the Program of Interdisciplinary Research of Stanford University. We are grateful to Rene Girard, the Program Director, for making it possible with the help of the Mellon Foundation.
Author: José Javier Otero
Publisher: Springer Nature
Published: 2021-04-30
Total Pages: 266
ISBN-13: 3030691705
DOWNLOAD EBOOKThis volume provides a balanced and realistic review of the current state of glioblastoma, ranging from traditional histological review, molecular pathology of glioma, modern radiomics, neurosurgical focus, and integration of treatment plans by neuro-oncologists. The book reviews basic principles such as epidemiology and etiology, and modern 2016 WHO classification of CNS tumors. Chapters cover a general overview of common molecular techniques used in molecular pathology, molecular pathology in a developing country, key drivers of patient outcomes and predictors of response to radiation and/or chemotherapy treatment, and immunohistochemical surrogates for key molecular pathology. It concludes with reviews on radiomics, animal and stem cell models of glioblastoma, and a chapter on the emerging field of Glioblastoma Neuroscience. Precision Molecular Pathology of Glioblastoma is intended for pathology residents and fellows interested in glioblastoma, general surgical pathologists who need reviews on how to implement modern glioblastoma classification, as well as neuro-radiologists, oncologists, and radiation oncologists needing a holistic perspective to glioblastoma diagnosis and management.
Author: Hendrik Richter
Publisher: Springer Science & Business Media
Published: 2013-11-19
Total Pages: 577
ISBN-13: 3642418880
DOWNLOAD EBOOKThis book is concerned with recent advances in fitness landscapes. The concept of fitness landscapes originates from theoretical biology and refers to a framework for analysing and visualizing the relationships between genotypes, phenotypes and fitness. These relationships lay at the centre of attempts to mathematically describe evolutionary processes and evolutionary dynamics. The book addresses recent advances in the understanding of fitness landscapes in evolutionary biology and evolutionary computation. In the volume, experts in the field of fitness landscapes present these findings in an integrated way to make it accessible to a number of audiences: senior undergraduate and graduate students in computer science, theoretical biology, physics, applied mathematics and engineering, but also researcher looking for a reference or/and entry point into using fitness landscapes for analysing algorithms. Also practitioners wanting to employ fitness landscape techniques for evaluating bio- and nature-inspired computing algorithms can find valuable material in the book. For teaching proposes, the book could also be used as a reference handbook.
