Interpretability of Machine Intelligence in Medical Image Computing, and Topological Data Analysis and Its Applications for Medical Data

Interpretability of Machine Intelligence in Medical Image Computing, and Topological Data Analysis and Its Applications for Medical Data

Author: Mauricio Reyes

Publisher: Springer Nature

Published: 2021-09-21

Total Pages: 138

ISBN-13: 3030874443

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This book constitutes the refereed joint proceedings of the 4th International Workshop on Interpretability of Machine Intelligence in Medical Image Computing, iMIMIC 2020, and the First International Workshop on Topological Data Analysis and Its Applications for Medical Data, TDA4MedicalData 2021, held on September 27, 2021, in conjunction with the 24th International Conference on Medical Imaging and Computer-Assisted Intervention, MICCAI 2021. The 7 full papers presented at iMIMIC 2021 and 5 full papers held at TDA4MedicalData 2021 were carefully reviewed and selected from 12 submissions each. The iMIMIC papers focus on introducing the challenges and opportunities related to the topic of interpretability of machine learning systems in the context of medical imaging and computer assisted intervention. TDA4MedicalData is focusing on using TDA techniques to enhance the performance, generalizability, efficiency, and explainability of the current methods applied to medical data.


Medical Image Computing and Computer Assisted Intervention – MICCAI 2022

Medical Image Computing and Computer Assisted Intervention – MICCAI 2022

Author: Linwei Wang

Publisher: Springer Nature

Published: 2022-09-14

Total Pages: 796

ISBN-13: 3031164318

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The eight-volume set LNCS 13431, 13432, 13433, 13434, 13435, 13436, 13437, and 13438 constitutes the refereed proceedings of the 25th International Conference on Medical Image Computing and Computer-Assisted Intervention, MICCAI 2022, which was held in Singapore in September 2022. The 574 revised full papers presented were carefully reviewed and selected from 1831 submissions in a double-blind review process. The papers are organized in the following topical sections: Part I: Brain development and atlases; DWI and tractography; functional brain networks; neuroimaging; heart and lung imaging; dermatology; Part II: Computational (integrative) pathology; computational anatomy and physiology; ophthalmology; fetal imaging; Part III: Breast imaging; colonoscopy; computer aided diagnosis; Part IV: Microscopic image analysis; positron emission tomography; ultrasound imaging; video data analysis; image segmentation I; Part V: Image segmentation II; integration of imaging with non-imaging biomarkers; Part VI: Image registration; image reconstruction; Part VII: Image-Guided interventions and surgery; outcome and disease prediction; surgical data science; surgical planning and simulation; machine learning – domain adaptation and generalization; Part VIII: Machine learning – weakly-supervised learning; machine learning – model interpretation; machine learning – uncertainty; machine learning theory and methodologies.


Topology for Computing

Topology for Computing

Author: Afra J. Zomorodian

Publisher: Cambridge University Press

Published: 2005-01-10

Total Pages: 264

ISBN-13: 9781139442633

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The emerging field of computational topology utilizes theory from topology and the power of computing to solve problems in diverse fields. Recent applications include computer graphics, computer-aided design (CAD), and structural biology, all of which involve understanding the intrinsic shape of some real or abstract space. A primary goal of this book is to present basic concepts from topology and Morse theory to enable a non-specialist to grasp and participate in current research in computational topology. The author gives a self-contained presentation of the mathematical concepts from a computer scientist's point of view, combining point set topology, algebraic topology, group theory, differential manifolds, and Morse theory. He also presents some recent advances in the area, including topological persistence and hierarchical Morse complexes. Throughout, the focus is on computational challenges and on presenting algorithms and data structures when appropriate.


Medical Imaging Informatics

Medical Imaging Informatics

Author: Alex A.T. Bui

Publisher: Springer Science & Business Media

Published: 2009-12-01

Total Pages: 454

ISBN-13: 1441903852

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Medical Imaging Informatics provides an overview of this growing discipline, which stems from an intersection of biomedical informatics, medical imaging, computer science and medicine. Supporting two complementary views, this volume explores the fundamental technologies and algorithms that comprise this field, as well as the application of medical imaging informatics to subsequently improve healthcare research. Clearly written in a four part structure, this introduction follows natural healthcare processes, illustrating the roles of data collection and standardization, context extraction and modeling, and medical decision making tools and applications. Medical Imaging Informatics identifies core concepts within the field, explores research challenges that drive development, and includes current state-of-the-art methods and strategies.


Explainable AI: Interpreting, Explaining and Visualizing Deep Learning

Explainable AI: Interpreting, Explaining and Visualizing Deep Learning

Author: Wojciech Samek

Publisher: Springer Nature

Published: 2019-09-10

Total Pages: 435

ISBN-13: 3030289540

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The development of “intelligent” systems that can take decisions and perform autonomously might lead to faster and more consistent decisions. A limiting factor for a broader adoption of AI technology is the inherent risks that come with giving up human control and oversight to “intelligent” machines. For sensitive tasks involving critical infrastructures and affecting human well-being or health, it is crucial to limit the possibility of improper, non-robust and unsafe decisions and actions. Before deploying an AI system, we see a strong need to validate its behavior, and thus establish guarantees that it will continue to perform as expected when deployed in a real-world environment. In pursuit of that objective, ways for humans to verify the agreement between the AI decision structure and their own ground-truth knowledge have been explored. Explainable AI (XAI) has developed as a subfield of AI, focused on exposing complex AI models to humans in a systematic and interpretable manner. The 22 chapters included in this book provide a timely snapshot of algorithms, theory, and applications of interpretable and explainable AI and AI techniques that have been proposed recently reflecting the current discourse in this field and providing directions of future development. The book is organized in six parts: towards AI transparency; methods for interpreting AI systems; explaining the decisions of AI systems; evaluating interpretability and explanations; applications of explainable AI; and software for explainable AI.


Shape Analysis in Medical Image Analysis

Shape Analysis in Medical Image Analysis

Author: Shuo Li

Publisher: Springer Science & Business Media

Published: 2014-01-28

Total Pages: 441

ISBN-13: 3319038133

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This book contains thirteen contributions from invited experts of international recognition addressing important issues in shape analysis in medical image analysis, including techniques for image segmentation, registration, modelling and classification and applications in biology, as well as in cardiac, brain, spine, chest, lung and clinical practice. This volume treats topics such as for example, anatomic and functional shape representation and matching; shape-based medical image segmentation; shape registration; statistical shape analysis; shape deformation; shape-based abnormity detection; shape tracking and longitudinal shape analysis; machine learning for shape modeling and analysis; shape-based computer-aided-diagnosis; shape-based medical navigation; benchmark and validation of shape representation, analysis and modeling algorithms. This work will be of interest to researchers, students and manufacturers in the fields of artificial intelligence, bioengineering, biomechanics, computational mechanics, computational vision, computer sciences, human motion, mathematics, medical imaging, medicine, pattern recognition and physics.


Deep Learning and Convolutional Neural Networks for Medical Image Computing

Deep Learning and Convolutional Neural Networks for Medical Image Computing

Author: Le Lu

Publisher: Springer

Published: 2017-07-12

Total Pages: 327

ISBN-13: 331942999X

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This book presents a detailed review of the state of the art in deep learning approaches for semantic object detection and segmentation in medical image computing, and large-scale radiology database mining. A particular focus is placed on the application of convolutional neural networks, with the theory supported by practical examples. Features: highlights how the use of deep neural networks can address new questions and protocols, as well as improve upon existing challenges in medical image computing; discusses the insightful research experience of Dr. Ronald M. Summers; presents a comprehensive review of the latest research and literature; describes a range of different methods that make use of deep learning for object or landmark detection tasks in 2D and 3D medical imaging; examines a varied selection of techniques for semantic segmentation using deep learning principles in medical imaging; introduces a novel approach to interleaved text and image deep mining on a large-scale radiology image database.


Artificial Intelligence in Drug Design

Artificial Intelligence in Drug Design

Author: Alexander Heifetz

Publisher: Humana

Published: 2022-11-05

Total Pages: 0

ISBN-13: 9781071617892

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This volume looks at applications of artificial intelligence (AI), machine learning (ML), and deep learning (DL) in drug design. The chapters in this book describe how AI/ML/DL approaches can be applied to accelerate and revolutionize traditional drug design approaches such as: structure- and ligand-based, augmented and multi-objective de novo drug design, SAR and big data analysis, prediction of binding/activity, ADMET, pharmacokinetics and drug-target residence time, precision medicine and selection of favorable chemical synthetic routes. How broadly are these approaches applied and where do they maximally impact productivity today and potentially in the near future. Written in the highly successful Methods in Molecular Biology series format, chapters include introductions to their respective topics, lists of the necessary software and tools, step-by-step, readily reproducible modeling protocols, and tips on troubleshooting and avoiding known pitfalls. Cutting-edge and unique, Artificial Intelligence in Drug Design is a valuable resource for structural and molecular biologists, computational and medicinal chemists, pharmacologists and drug designers.


Intelligent Computing

Intelligent Computing

Author: Kohei Arai

Publisher: Springer Nature

Published:

Total Pages: 1269

ISBN-13: 3030801268

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This book is a comprehensive collection of chapters focusing on the core areas of computing and their further applications in the real world. Each chapter is a paper presented at the Computing Conference 2021 held on 15-16 July 2021. Computing 2021 attracted a total of 638 submissions which underwent a double-blind peer review process. Of those 638 submissions, 235 submissions have been selected to be included in this book. The goal of this conference is to give a platform to researchers with fundamental contributions and to be a premier venue for academic and industry practitioners to share new ideas and development experiences. We hope that readers find this volume interesting and valuable as it provides the state-of-the-art intelligent methods and techniques for solving real-world problems. We also expect that the conference and its publications is a trigger for further related research and technology improvements in this important subject. .


Machine Learning for Audio, Image and Video Analysis

Machine Learning for Audio, Image and Video Analysis

Author: Francesco Camastra

Publisher: Springer

Published: 2015-07-21

Total Pages: 564

ISBN-13: 144716735X

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This second edition focuses on audio, image and video data, the three main types of input that machines deal with when interacting with the real world. A set of appendices provides the reader with self-contained introductions to the mathematical background necessary to read the book. Divided into three main parts, From Perception to Computation introduces methodologies aimed at representing the data in forms suitable for computer processing, especially when it comes to audio and images. Whilst the second part, Machine Learning includes an extensive overview of statistical techniques aimed at addressing three main problems, namely classification (automatically assigning a data sample to one of the classes belonging to a predefined set), clustering (automatically grouping data samples according to the similarity of their properties) and sequence analysis (automatically mapping a sequence of observations into a sequence of human-understandable symbols). The third part Applications shows how the abstract problems defined in the second part underlie technologies capable to perform complex tasks such as the recognition of hand gestures or the transcription of handwritten data. Machine Learning for Audio, Image and Video Analysis is suitable for students to acquire a solid background in machine learning as well as for practitioners to deepen their knowledge of the state-of-the-art. All application chapters are based on publicly available data and free software packages, thus allowing readers to replicate the experiments.