Quantitative MRI of the Brain

Quantitative MRI of the Brain

Author: Paul Tofts

Publisher: John Wiley & Sons

Published: 2005-08-19

Total Pages: 650

ISBN-13: 0470869496

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2004 BMA Medical Book Competition Winner (Radiology category) “This is an exciting book, with a new approach to use of the MRI scanner. It bridges the gap between clinical research and general neuro-radiological practice. It is accessible to the clinical radiologist, and yet thorough in its treatment of the underlying physics and of the science of measurement. It is likely to become a classic.” British Medical Association This indispensable 'how to' manual of quantitative MR is essential for anyone who wants to use the gamut of modern quantitative methods to measure the effects of neurological disease, its progression, and its response to treatment. It contains both the methodology and clinical applications, reflecting the increasing interest in quantitative MR in studying disease and its progression. The editor is an MR scientist with an international reputation for high quality research The contributions are written jointly by MR physicists and MR clinicians, producing a practical book for both the research and medical communities A practical book for both the research and medical communities “Paul Tofts has succeeded brilliantly in capturing the essence of what needs to become the future of radiology in particular, and medicine in general – quantitative measurements of disease.” Robert I. Grossman, M.D. New York, University School of Medicine (from the Foreword)


Metabolism of Drugs and Other Xenobiotics

Metabolism of Drugs and Other Xenobiotics

Author: Pavel Anzenbacher

Publisher: John Wiley & Sons

Published: 2012-05-29

Total Pages: 755

ISBN-13: 352732903X

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A practice-oriented desktop reference for medical professionals, toxicologists and pharmaceutical researchers, this handbook provides systematic coverage of the metabolic pathways of all major classes of xenobiotics in the human body. The first part comprehensively reviews the main enzyme systems involved in biotransformation and how they are orchestrated in the body, while parts two to four cover the three main classes of xenobiotics: drugs, natural products, environmental pollutants. The part on drugs includes more than 300 substances from five major therapeutic groups (central nervous system, cardiovascular system, cancer, infection, and pain) as well as most drugs of abuse including nicotine, alcohol and "designer" drugs. Selected, well-documented case studies from the most important xenobiotics classes illustrate general principles of metabolism, making this equally useful for teaching courses on pharmacology, drug metabolism or molecular toxicology. Of particular interest, and unique to this volume is the inclusion of a wide range of additional xenobiotic compounds, including food supplements, herbal preparations, and agrochemicals.


The Graded Motor Imagery Handbook

The Graded Motor Imagery Handbook

Author: G. Lorimer Moseley

Publisher: Noigroup Publications

Published: 2012

Total Pages: 159

ISBN-13: 0987246755

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Graded Motor Imagery is a complex series of treatments including graded left/right judgement exercises, imagined movements and use of mirrors targeting neuropathic pain problems.


Manual Therapy for Musculoskeletal Pain Syndromes

Manual Therapy for Musculoskeletal Pain Syndromes

Author: Cesar Fernandez de las Penas

Publisher: Elsevier Health Sciences

Published: 2015-06-26

Total Pages: 837

ISBN-13: 070205576X

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A pioneering, one-stop manual which harvests the best proven approaches from physiotherapy research and practice to assist the busy clinician in real-life screening, diagnosis and management of patients with musculoskeletal pain across the whole body. Led by an experienced editorial team, the chapter authors have integrated both their clinical experience and expertise with reasoning based on a neurophysiologic rationale with the most updated evidence. The textbook is divided into eleven sections, covering the top evidence-informed techniques in massage, trigger points, neural muscle energy, manipulations, dry needling, myofascial release, therapeutic exercise and psychological approaches. In the General Introduction, several authors review the epidemiology of upper and lower extremity pain syndromes and the process of taking a comprehensive history in patients affected by pain. In Chapter 5, the basic principles of the physical examination are covered, while Chapter 6 places the field of manual therapy within the context of contemporary pain neurosciences and therapeutic neuroscience education. For the remaining sections, the textbook alternates between the upper and lower quadrants. Sections 2 and 3 provide state-of-the-art updates on mechanical neck pain, whiplash, thoracic outlet syndrome, myelopathy, radiculopathy, peri-partum pelvic pain, joint mobilizations and manipulations and therapeutic exercises, among others. Sections 4 to 9 review pertinent and updated aspects of the shoulder, hip, elbow, knee, the wrist and hand, and finally the ankle and foot. The last two sections of the book are devoted to muscle referred pain and neurodynamics. The only one-stop manual detailing examination and treatment of the most commonly seen pain syndromes supported by accurate scientific and clinical data Over 800 illustrations demonstrating examination procedures and techniques Led by an expert editorial team and contributed by internationally-renowned researchers, educators and clinicians Covers epidemiology and history-taking Highly practical with a constant clinical emphasis


Pain Management and the Opioid Epidemic

Pain Management and the Opioid Epidemic

Author: National Academies of Sciences, Engineering, and Medicine

Publisher: National Academies Press

Published: 2017-09-28

Total Pages: 483

ISBN-13: 0309459575

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Drug overdose, driven largely by overdose related to the use of opioids, is now the leading cause of unintentional injury death in the United States. The ongoing opioid crisis lies at the intersection of two public health challenges: reducing the burden of suffering from pain and containing the rising toll of the harms that can arise from the use of opioid medications. Chronic pain and opioid use disorder both represent complex human conditions affecting millions of Americans and causing untold disability and loss of function. In the context of the growing opioid problem, the U.S. Food and Drug Administration (FDA) launched an Opioids Action Plan in early 2016. As part of this plan, the FDA asked the National Academies of Sciences, Engineering, and Medicine to convene a committee to update the state of the science on pain research, care, and education and to identify actions the FDA and others can take to respond to the opioid epidemic, with a particular focus on informing FDA's development of a formal method for incorporating individual and societal considerations into its risk-benefit framework for opioid approval and monitoring.


Exercise Physiology: Integrating Theory and Application

Exercise Physiology: Integrating Theory and Application

Author: William Kraemer

Publisher: Lippincott Williams & Wilkins

Published: 2020-08-24

Total Pages: 1759

ISBN-13: 1975166094

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Build the foundation of scientific knowledge and practical decision-making skills needed to excel in an exercise training career Master the core concepts of exercise physiology and learn how to apply them to the real-world challenges of exercise training with Exercise Physiology: Integrating Theory and Application, Third Edition. Designed to connect theory to practice, this engaging, accessible text gives students a thorough understanding of how the body adapts to exercise and environmental stresses and how basic physiology informs practical decisions. This new edition expands the coverage of practical applications, extends on our growing scientific knowledge of exercise physiology, explores the topic of “Exercise is Medicine”, and offers more guidance on finding reliable research-based answers to real-life questions. New content, as well as updated coverage of the endocrine system, applying research, nutritional support, and environmental effects make this the perfect resource to support the diverse case scenarios seen by personal trainers, strength coaches, fitness instructors, athletic trainers, and other exercise professionals.


Somatoform Disorders

Somatoform Disorders

Author: Mario Maj

Publisher: John Wiley & Sons

Published: 2005-11-01

Total Pages: 414

ISBN-13: 0470027401

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Be Guided by the Evidence... Somatoform disorders are more common than many clinicians realize and are often underdiagnosed and poorly managed. This practical guide provides a comprehensive overview of all somatoform disorders. It aims to enable the mental health practitioner to properly diagnose and manage the disorders as well as to provide the appropriate advice to colleagues of other medical disciplines. Somatoform Disorders offers: * Detailed coverage of the concepts of each disorder: diagnosis, classification, co-morbidities and course and outcome * An outline of clinical, biological and psychosocial research in the area * An overview of clinical management and future perspectives * The unique series format of systematic reviews followed by commentaries Somatoform Disorders is the ninth volume of the WPA Series "Evidence and Experience in Psychiatry. The book is an unbiased and reliable reference point for all psychiatrists, psychologists, mental health nurses and policy makers.