Immunoglobulin Gene Expression in Development and Disease
Author: Paolo Casali
Publisher:
Published: 2006
Total Pages:
ISBN-13:
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Author: Paolo Casali
Publisher:
Published: 2006
Total Pages:
ISBN-13:
DOWNLOAD EBOOKAuthor: Tasuku Honjo
Publisher: Academic Press
Published: 2012-12-02
Total Pages: 429
ISBN-13: 0080984487
DOWNLOAD EBOOKImmunoglobin Genes is the first comprehensive book on the structure, function, and expression of the genes encoding antibodies in normal and neoplastic cells.
Author: F. Calabi
Publisher: Elsevier
Published: 1987-12-01
Total Pages: 261
ISBN-13: 0080860761
DOWNLOAD EBOOKOur understanding of the molecular genetics of immunoglobulins has been enormously advanced by the application of recombinant DNA technology. This new volume in the popular series New Comprehensive Biochemistry contains eight chapters that draw together reviews summarising the research into immunoglobulins and the arrangement, rearrangement and expression of their gene structure.Molecular Genetics of Immunoglobulin will be of particular importance to those working in the areas of genetics and molecular biology, immunology, and cell biology.
Author: Karin Johansson
Publisher:
Published: 1995
Total Pages: 146
ISBN-13:
DOWNLOAD EBOOKAuthor: Catherine M. Rossi
Publisher:
Published: 1990
Total Pages: 118
ISBN-13:
DOWNLOAD EBOOKAuthor: Marc Feldmann
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 347
ISBN-13: 1461250145
DOWNLOAD EBOOKThis book encompasses the proceedings of a conference held at Trinity College, Oxford on September 21-25, 1985 organized by a committee comprised of Drs. M. Crumpton, M. Feldmann, A. McMichael, and E. Simpson, and advised by many friends and colleagues. The immune response gene workshops that took place were based on the need to understand why certain experimental animal strains were high responders and others were low responders. It was assumed that identification of the immune response (Ir) genes and definition of their products would explain high and low responder status. Research in the ensuing years has identified the Ir gene products involved in antibody responses as the la antigens, or MHC Class II antigens. These proteins are now well defined as members of the immunoglobulin gene superfamily, and their domain structure is known. Epitopes have been defined by multiple mono clonal antibodies and regions of hypervariability identified. Their genes have been identified and cloned. The basic observation of high and low responsive ness to antigen is still not understood in mechanistic terms, however, at either the cellular or molecular level. This is because the rate of progress in immune regulation has been far slower than in the molecular biology of the MHC Class II antigens. This is not surprising, since immune regulation is a very complex field at the crossroads of many disciplines.
Author: Azad K. Kaushik
Publisher: CRC Press
Published: 2014-05-01
Total Pages: 265
ISBN-13: 1771880147
DOWNLOAD EBOOKThis contemporary book covers significant new knowledge that has emerged during the last two decades and, thus, provides novel antibody phylogenetic perspectives relevant to development of new antibody-based therapeutics and vaccines. It fills a much-needed niche in the area of immunoglobulin genetics across species from a comparative perspective. New insights and perspectives from immunoglobulin genetics from species such as sea lamprey, cattle, marsupial, bat, rat, rabbit, and swine—other species than the traditional subjects of mice and humans—are relevant to antibody design and engineering. These new perspectives find direct application in the cutting-edge areas of antibody design, engineering and therapeutics, antibody-drug conjugates, and novel antibody-based vaccines. This book fills the need to provide updated knowledge of this newly exploded area that is finding applications in new drug development. No other competing books on the topic are available in the market. The book will be of great interest to immunologists, immunology researchers, immunogeneticists, researchers in pharmaceutical science, those involved in the infectious disease and antibody therapeutics areas, and many others.
Author: Hong Luo
Publisher:
Published: 2007
Total Pages:
ISBN-13:
DOWNLOAD EBOOKAuthor: Kenneth Murphy
Publisher: Garland Science
Published: 2010-06-22
Total Pages:
ISBN-13: 9780815344575
DOWNLOAD EBOOKThe Janeway's Immunobiology CD-ROM, Immunobiology Interactive, is included with each book, and can be purchased separately. It contains animations and videos with voiceover narration, as well as the figures from the text for presentation purposes.
Author:
Publisher: CSHL Press
Published: 1999
Total Pages: 656
ISBN-13: 9780879695705
DOWNLOAD EBOOKProvides a dialogue on the nature of the membrane signals and intracytoplasmic events that provoke immunity. The debate ranges over biochemistry, physiology, molecular genetics, as well as classical cellular immunology. Input came from over 70 of the world's leading investigators.