Hypercalcemia of Malignancy
Hypercalcemia of Malignancy

Author: Friedhelm Raue

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 238

ISBN-13: 3642850731

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Hypercalcemia is the most common life-threatening metabolic disorder associated with cancer. The pathophysiological, epidemiological and clinical aspects of hypercalcemia of malignancy are presented in this issue, with a focus on the recently discovered humoral factor responsible for the development of hypercalcemia. With a better understanding of the pathophysiology of this condition and the development of new potent drugs, capable of inhibiting bone resorption, especially bisphosphonates, the clinician will be more successful in correcting hypercalcemia in the great majority of patients.

Clinical Endocrinology of Companion Animals
Clinical Endocrinology of Companion Animals

Author: Jacquie Rand

Publisher: John Wiley & Sons

Published: 2013-01-22

Total Pages: 544

ISBN-13: 081380583X

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Clinical Endocrinology of Companion Animals offers fast access to clinically relevant information on managing the patient with endocrine disease. Written by leading experts in veterinary endocrinology, each chapter takes the same structure to aid in the rapid retrieval of information, offering information on pathogenesis, signalment, clinical signs, diagnosis, differential diagnosis, treatment, prognosis, and prevention for a broad list of endocrine disorders. Chapters begin with brief summaries for quick reference, then delve into greater detail. With complete coverage of the most common endocrine diseases, the book includes chapters on conditions in dogs, cats, horses, ferrets, reptiles, and other species. Clinical Endocrinology of Companion Animals is a highly practical resource for any veterinarian treating these common diseases.

Quick Guide to Psychiatric Emergencies
Quick Guide to Psychiatric Emergencies

Author: Kimberly D. Nordstrom

Publisher: Springer

Published: 2018-03-07

Total Pages: 282

ISBN-13: 3319582607

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This volume provides an “on-the-go” guide to the most common behavioral emergencies a physician may encounter. Each chapter represents a disease state or symptom cluster and concisely summarizes the disease state, provides background, symptoms and signs, differential diagnoses, and immediate and long-term treatment options. All chapters conclude with a diagnosis or treatment algorithm or another easy-to-use visual tool. Chapters named after a specific disease state or symptom cluster, arranged alphabetically for use in the field. The text begins with chapters covering patient evaluation: getting a good history, suicide risk assessment, physical exam, and when and how to use studies. Written by experts in psychiatry and emergency medicine, this text is the first to consider both medical perspectives in a concise guide. Quick Guide to Psychiatric Emergencies is an excellent resource for psychiatrists, emergency medicine physicians, residents, nurses, and other medical professionals that handle behavioral emergencies on a regular basis.

Principles and Practice of Endocrinology and Metabolism
Principles and Practice of Endocrinology and Metabolism

Author: Kenneth L. Becker

Publisher: Lippincott Williams & Wilkins

Published: 2001

Total Pages: 2500

ISBN-13: 9780781717502

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Established as the foremost text in the field, Principles and Practice of Endocrinology and Metabolism is now in its thoroughly revised, updated Third Edition. This practical, clinically relevant, and comprehensive text covers the entire field of endocrinology and metabolism, including the diffuse endocrine system; morphology and physiology; diagnosis and treatment of endocrine diseases; endocrinology of the female; hormones and cancer; and much more. The Third Edition contains new chapters reflecting the latest advances and features expanded coverage of genetics and the endocrinology of sepsis. More than 1,400 illustrations complement the text. A drug formulary appears at the back of the book.

Calcium-Sensing Receptor
Calcium-Sensing Receptor

Author: Naibedya Chattopadhyay

Publisher: Springer Science & Business Media

Published: 2003

Total Pages: 310

ISBN-13: 9781402073144

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Calcium-Sensing Receptor provides an overview of various aspects of the calcium receptor's biochemistry, physiology and pathophysiology that is suitable both for those who have been working in the field of Ca2+0-sensing as well as those who are new to this discipline. Calcium-Sensing Receptor is the nineteenth volume published in the Endocrine Updates book series under the Series Editorship of Shlomo Melmed, MD.

Parathyroid Hormone - Related Protein
Parathyroid Hormone - Related Protein

Author: Bernard P. Halloran

Publisher: CRC Press

Published: 1992-03-04

Total Pages: 26

ISBN-13: 9780849345395

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Since its discovery, a substantial body of information has been amassed concerning the functions of parathyroid hormone-related protein (PTHrP) in normal and malignant states. This book provides a state-of-the-art discussion of the major aspects of PTHrP biology and pathophysiology, in addition to presenting a historical perspective and discussions on the molecular biology of PTHrP, its mechanism of action, bioassays and radioimmunoassays, and its role in normal physiology. The book will be a primary resource for physicians interested in the clinical aspects of paraneoplastic hypercalcemia and mineral metabolic disorders. It will also serve as a primary resource for basic scientists in skeletal and renal physiology, tumor biology, and hormone action. PROPOSED CONTENTS: INTRODUCTION (A. BROADUS). HISTORY. Identification of Clinical Syndrome of MAH. Evidence for Unique PTH-Like Factor. ISOLATION AND PURIFICATION OF PTHrP. CHEMICAL DESCRIPTION OF PTHrP. MOLECULAR BIOLOGY OF PTHrP (D. GOLTZMAN). GENE STRUCTURE. Intron and Exon Boundaries. Identification of Promoter and Putative Regulatory Elements. Alternative Splicing. EVOLUTIONARY RELATIONSHIP TO PTH GENE. EXPRESSION OF PTHrP (M. THIEDE). EXPRESSION IN TUMOR TISSUES. EXPRESSION IN NORMAL TISSUES. EXPRESSION IN CELL CULTURE. SECRETED FORMS. ASSAY OF PTHrP AND ITS ROLE IN MAH (A. STEWART, W. BURTIS). BIO- AND RADIOIMMUNOASSAYS. SERUM CONCENTRATIONS IN NORMAL SUBJECTS AND CANCER PATIENTS. RELATIONSHIP BETWEEN EXPRESSION OF PTHRP AND HYPERCALCEMIA. EFFECTS ON TARGET TISSUES. Bone. Kidney. ROLE OF FACTORS OTHER THAN PTHrP IN MAH. MOLECULAR MECHANISM OF ACTION OF PTHrP (R. NISSENSON, G. STREWLER). RECEPTOR BINDING AND CELL SIGNALING. IMPLICATIONS FOR STRUCTURE-FUNCTION FOR PTHrP FAMILY. PTHrP IN NORMAL PHYSIOLOGY (J. MARTIN). EMBRYONIC AND NEONATAL DEVELOPMENT. LACTATION. RELATIONSHIP TO PTH.

Store-Operated Calcium Channels
Store-Operated Calcium Channels

Author:

Publisher: Academic Press

Published: 2013-07-24

Total Pages: 307

ISBN-13: 0124079385

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Store-operated calcium channels are found in most animal cells and regulate many cellular functions including cell division, growth, differentiation, and cell death. This volume provides a concise and informative overview of the principles of store-operated calcium entry and the key developments in the field from researchers who have led these advances. The overall goal of the volume is to provide interested students and investigators with sufficient information to enable a broad understanding of the progress and current excitement in the field. The volume contains a wealth of information that even experienced investigators in the field will find useful. - The volume provides a comprehensive overview of the mechanisms and functions of store-operated calcium channels - Contributors are authoritative researchers who have produced important advances in the field - The volume is well-illustrated with cartoons and data to facilitate easy comprehension of the subject

Manual of Endocrinology and Metabolism
Manual of Endocrinology and Metabolism

Author: Norman Lavin

Publisher: Lippincott Williams & Wilkins

Published: 2009

Total Pages: 864

ISBN-13: 9780781768863

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Now in its Fourth Edition, this Spiral® Manual presents clinical information and protocols in outline format for evaluation and treatment of most endocrine disorders in children, adolescents, and adults. This thoroughly updated edition includes an introduction to risk assessment and screening and results of recent clinical trials and their implications for treatment and prevention. Also included are summaries of recent guidelines from the Endocrine Society and the American Academy of Clinical Endocrinology for prevention and management of many endocrine disorders including diabetes, growth hormone deficiency, dysmetabolic syndrome, dyslipidemia, and obesity. New chapters focus on comorbidities of Type II diabetes mellitus in children and use of growth hormone in adults.