The Human Experiment

The Human Experiment

Author: Jane Poynter

Publisher: Basic Books

Published: 2006-08-18

Total Pages: 384

ISBN-13: 9781560257752

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It's a story that has never been told … until now. Imagine being sealed into a closed environment for two years — cut off from the outside world with only seven other people — enduring never-ending hunger, severely low levels of oxygen, and extremely difficult relationships. Crew members struggled to survive in Biosphere 2, where they swore nothing would go in or out — no food or water, not even air — all in the name of science. For the first time, biospherian Jane Poynter — who lived and loved in the Biosphere — is ready to share what really happened in there. She takes readers on a riveting, fast-paced trip through shattered lives, scientific discovery, cults, love, fears of insanity, and inspiring human endurance. The eight biospherians who closed themselves into the Biosphere emerged 730 days later… much wiser, thinner, and having done what many had said was impossible.


The Uses of Humans in Experiment

The Uses of Humans in Experiment

Author:

Publisher: BRILL

Published: 2016-03-11

Total Pages: 309

ISBN-13: 9004286713

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Scientific experimentation with humans has a long history. Combining elements of history of science with history of medicine, The Uses of Humans in Experiment illustrates how humans have grappled with issues of consent, and how scientists have balanced experience with empiricism to achieve insights for scientific as well as clinical progress. The modern incarnation of ethics has often been considered a product of the second half of the twentieth century, as enshrined in international laws and codes, but these authors remind us that this territory has long been debated, considered, and revisited as a fundamental part of the scientific enterprise that privileges humans as ideal subjects for advancing research.


Experiments in Democracy

Experiments in Democracy

Author: Benjamin J. Hurlbut

Publisher: Columbia University Press

Published: 2017-01-31

Total Pages: 376

ISBN-13: 0231542917

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Human embryo research touches upon strongly felt moral convictions, and it raises such deep questions about the promise and perils of scientific progress that debate over its development has become a moral and political imperative. From in vitro fertilization to embryonic stem cell research, cloning, and gene editing, Americans have repeatedly struggled with how to define the moral status of the human embryo, whether to limit its experimental uses, and how to contend with sharply divided public moral perspectives on governing science. Experiments in Democracy presents a history of American debates over human embryo research from the late 1960s to the present, exploring their crucial role in shaping norms, practices, and institutions of deliberation governing the ethical challenges of modern bioscience. J. Benjamin Hurlbut details how scientists, bioethicists, policymakers, and other public figures have attempted to answer a question of great consequence: how should the public reason about aspects of science and technology that effect fundamental dimensions of human life? Through a study of one of the most significant science policy controversies in the history of the United States, Experiments in Democracy paints a portrait of the complex relationship between science and democracy, and of U.S. society's evolving approaches to evaluating and governing science's most challenging breakthroughs.


Experiment and the Making of Meaning

Experiment and the Making of Meaning

Author: D.C. Gooding

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 316

ISBN-13: 9400907079

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. . . the topic of 'meaning' is the one topic discussed in philosophy in which there is literally nothing but 'theory' - literally nothing that can be labelled or even ridiculed as the 'common sense view'. Putnam, 'The Meaning of Meaning' This book explores some truths behind the truism that experimentation is a hallmark of scientific activity. Scientists' descriptions of nature result from two sorts of encounter: they interact with each other and with nature. Philosophy of science has, by and large, failed to give an account of either sort of interaction. Philosophers typically imagine that scientists observe, theorize and experiment in order to produce general knowledge of natural laws, knowledge which can be applied to generate new theories and technologies. This view bifurcates the scientist's world into an empirical world of pre-articulate experience and know how and another world of talk, thought and argument. Most received philosophies of science focus so exclusively on the literary world of representations that they cannot begin to address the philosophical problems arising from the interaction of these worlds: empirical access as a source of knowledge, meaning and reference, and of course, realism. This has placed the epistemological burden entirely on the predictive role of experiment because, it is argued, testing predictions is all that could show that scientists' theorizing is constrained by nature. Here a purely literary approach contributes to its own demise. The epistemological significance of experiment turns out to be a theoretical matter: cruciality depends on argument, not experiment.


Designing Human Practices

Designing Human Practices

Author: Paul Rabinow

Publisher: University of Chicago Press

Published: 2012-05-21

Total Pages: 213

ISBN-13: 0226703150

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In 2006 anthropologists Paul Rabinow and Gaymon Bennett set out to rethink the role that human sciences play in biological research, creating the Human Practices division of the Synthetic Biology Engineering Research Center—a facility established to create design standards for the engineering of new enzymes, genetic circuits, cells, and other biological entities—to formulate a new approach to the ethical, security, and philosophical considerations of controversial biological work. They sought not simply to act as watchdogs but to integrate the biosciences with their own discipline in a more fundamentally interdependent way, inventing a new, dynamic, and experimental anthropology that they could bring to bear on the center’s biological research. Designing Human Practices is a detailed account of this anthropological experiment and, ultimately, its rejection. It provides new insights into the possibilities and limitations of collaboration, and diagnoses the micro-politics which effectively constrained the potential for mutual scientific flourishing. Synthesizing multiple disciplines, including biology, genetics, anthropology, and philosophy, alongside a thorough examination of funding entities such as the National Science Foundation, Designing Human Practices pushes the social study of science into new and provocative territory, utilizing a real-world experience as a springboard for timely reflections on how the human and life sciences can and should transform each other.


Acres of Skin

Acres of Skin

Author: Allen M. Hornblum

Publisher: Routledge

Published: 2013-05-13

Total Pages: 344

ISBN-13: 1134001649

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At a time of increased interest and renewed shock over the Tuskegee syphilis experiments, Acres of Skin sheds light on yet another dark episode of American medical history. In this disturbing expose, Allen M. Hornblum tells the story of Philadelphia's Holmesburg Prison.


Doctors from Hell

Doctors from Hell

Author: Vivien Spitz

Publisher: Sentient Publications

Published: 2005

Total Pages: 354

ISBN-13: 1591810329

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A chilling story of human depravity and ultimate justice, told for the first time by an eyewitness court reporter for the Nuremberg war crimes trial of Nazi doctors. This is the account of 22 men and 1 woman and the torturing and killing by experiment they authorized in the name of scientific research and patriotism. Doctors from Hell includes trial transcripts that have not been easily available to the general public and previously unpublished photographs used as evidence in the trial. The author describes the experience of being in bombed-out, dangerous, post-war Nuremberg, where she lived for two years while working on the trial. Once a Nazi sympathizer tossed bombs into the dining room of the hotel where she lived moments before she arrived for dinner. She takes us into the courtroom to hear the dramatic testimony and see the reactions of the defendants to the proceedings. This landmark trial resulted in the establishment of the Nuremberg code, which set the guidelines for medical research involving human beings. A significant addition to the literature on World War II and the Holocaust, medical ethics, human rights, and the barbaric depths to which human beings can descend.


When Experiments Travel

When Experiments Travel

Author: Adriana Petryna

Publisher: Princeton University Press

Published: 2009-04-27

Total Pages: 271

ISBN-13: 1400830826

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The phenomenal growth of global pharmaceutical sales and the quest for innovation are driving an unprecedented search for human test subjects, particularly in middle- and low-income countries. Our hope for medical progress increasingly depends on the willingness of the world's poor to participate in clinical drug trials. While these experiments often provide those in need with vital and previously unattainable medical resources, the outsourcing and offshoring of trials also create new problems. In this groundbreaking book, anthropologist Adriana Petryna takes us deep into the clinical trials industry as it brings together players separated by vast economic and cultural differences. Moving between corporate and scientific offices in the United States and research and public health sites in Poland and Brazil, When Experiments Travel documents the complex ways that commercial medical science, with all its benefits and risks, is being integrated into local health systems and emerging drug markets. Providing a unique perspective on globalized clinical trials, When Experiments Travel raises central questions: Are such trials exploitative or are they social goods? How are experiments controlled and how is drug safety ensured? And do these experiments help or harm public health in the countries where they are conducted? Empirically rich and theoretically innovative, the book shows that neither the language of coercion nor that of rational choice fully captures the range of situations and value systems at work in medical experiments today. When Experiments Travel challenges conventional understandings of the ethics and politics of transnational science and changes the way we think about global medicine and the new infrastructures of our lives.


Use of Laboratory Animals in Biomedical and Behavioral Research

Use of Laboratory Animals in Biomedical and Behavioral Research

Author: National Research Council

Publisher: National Academies Press

Published: 1988-02-01

Total Pages: 113

ISBN-13: 0309038391

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Scientific experiments using animals have contributed significantly to the improvement of human health. Animal experiments were crucial to the conquest of polio, for example, and they will undoubtedly be one of the keystones in AIDS research. However, some persons believe that the cost to the animals is often high. Authored by a committee of experts from various fields, this book discusses the benefits that have resulted from animal research, the scope of animal research today, the concerns of advocates of animal welfare, and the prospects for finding alternatives to animal use. The authors conclude with specific recommendations for more consistent government action.


A Century of Eugenics in America

A Century of Eugenics in America

Author: Paul A. Lombardo

Publisher: Indiana University Press

Published: 2011-01-06

Total Pages: 268

ISBN-13: 0253222699

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This volume assesses the history of eugenics in the United States and its status in the age of the Human Genome Project. The essays explore the early support of compulsory sterilization by doctors and legislators.