Helicobacter pylori in Human Diseases
Helicobacter pylori in Human Diseases

Author: Shigeru Kamiya

Publisher: Springer Nature

Published: 2019-10-22

Total Pages: 284

ISBN-13: 303021916X

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This book gathers a wealth of contributions on the virulence factors and pathogenic mechanism of Helicobacter pylori, prepared by leading international experts. In addition, it explores the epidemiology, diagnosis, treatment with drugs and probiotics, and prophylaxis by vaccination, reflecting the latest advances. H. pylori is a Gram negative microaerophilic bacterium that can produce various gastric diseases including gastritis, gastroduodenal ulceration, gastric cancer and gastric MALT lymphoma. Although efforts to combat H. pylori using a combination of proton pump inhibitor and several antimicrobial drugs have significantly decreased the burden of these gastric diseases, the microbial epidemiology and gastric pathogenesis following H. pylori infection are still not fully understood. Given its scope, the book offers a valuable resource not only for basic microbiologists, but also for researchers in the fields of pathology, biochemistry and genomics, as well as medical students/scientists.

Helicobacter Pylori - New Approaches of an Old Human Microorganism
Helicobacter Pylori - New Approaches of an Old Human Microorganism

Author: Bruna Maria Roesler

Publisher:

Published: 2019

Total Pages: 134

ISBN-13: 9781838811471

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Helicobacter pylori is an universally distributed bacterium which affects more than half of the world population. H. pylori infection causes persistent inflammation with different clinical outcomes in humans, including chronic gastritis, peptic ulcer disease and gastric cancer. The infection has also been associated with several extradigestive disorders. In this book there is a comprehensive overview of contributors on H. pylori infection in diverse areas, including virulence factors of H. pylori and their importance for the clinical outcome of the diseases, discussions about the principal therapeutic regimens of bacterium eradication, also considering the antimicrobial resistance. H. pylori is clearly a very interesting bacteria and great studies and discussions about all its aspects are welcome to the medical and scientific communities.

Molecular Pathogenesis and Signal Transduction by Helicobacter pylori
Molecular Pathogenesis and Signal Transduction by Helicobacter pylori

Author: Nicole Tegtmeyer

Publisher: Springer

Published: 2017-01-23

Total Pages: 364

ISBN-13: 3319505203

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This volume reviews the current state of research concerning bacterial virulence factors and the infection biology of Helicobacter pylori, which is the leading cause of peptic ulcers and gastric cancer worldwide. The chapters include cutting-edge findings on this fascinating microbe and discuss the general strategies of H. pylori infection and persistence, news on important H. pylori virulence factors, crosstalk with the microbiota, hot novel models and signaling mechanisms, risk factors of gastric disease and stomach cancer, and the impact of H. pylori infection on non-gastric diseases. Written by internationally respected scientists, this book will appeal to clinicians, researchers and advanced students alike.

Vaccines for the 21st Century
Vaccines for the 21st Century

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2001-02-21

Total Pages: 472

ISBN-13: 0309174988

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Vaccines have made it possible to eradicate the scourge of smallpox, promise the same for polio, and have profoundly reduced the threat posed by other diseases such as whooping cough, measles, and meningitis. What is next? There are many pathogens, autoimmune diseases, and cancers that may be promising targets for vaccine research and development. This volume provides an analytic framework and quantitative model for evaluating disease conditions that can be applied by those setting priorities for vaccine development over the coming decades. The committee describes an approach for comparing potential new vaccines based on their impact on morbidity and mortality and on the costs of both health care and vaccine development. The book examines: Lessons to be learned from the polio experience. Scientific advances that set the stage for new vaccines. Factors that affect how vaccines are used in the population. Value judgments and ethical questions raised by comparison of health needs and benefits. The committee provides a way to compare different forms of illness and set vaccine priorities without assigning a monetary value to lives. Their recommendations will be important to anyone involved in science policy and public health planning: policymakers, regulators, health care providers, vaccine manufacturers, and researchers.

Helicobacter Pylori
Helicobacter Pylori

Author: Bruna Maria Roesler

Publisher: BoD – Books on Demand

Published: 2019-09-18

Total Pages: 136

ISBN-13: 183881146X

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Helicobacter pylori is an universally distributed bacterium which affects more than half of the world population. H. pylori infection causes persistent inflammation with different clinical outcomes in humans, including chronic gastritis, peptic ulcer disease and gastric cancer. The infection has also been associated with several extradigestive disorders. In this book there is a comprehensive overview of contributors on H. pylori infection in diverse areas, including virulence factors of H. pylori and their importance for the clinical outcome of the diseases, discussions about the principal therapeutic regimens of bacterium eradication, also considering the antimicrobial resistance. H. pylori is clearly a very interesting bacteria and great studies and discussions about all its aspects are welcome to the medical and scientific communities.

Microbiology of Waterborne Diseases
Microbiology of Waterborne Diseases

Author:

Publisher: Academic Press

Published: 2013-11-08

Total Pages: 719

ISBN-13: 0124159761

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The second edition of Microbiology of Waterborne Diseases describes the diseases associated with water, their causative agents and the ways in which they gain access to water systems. The book is divided into sections covering bacteria, protozoa, and viruses. Other sections detail methods for detecting and identifying waterborne microorganisms, and the ways in which they are removed from water, including chlorine, ozone, and ultraviolet disinfection. The second edition of this handbook has been updated with information on biofilms and antimicrobial resistance. The impact of global warming and climate change phenomena on waterborne illnesses are also discussed. This book serves as an indispensable reference for public health microbiologists, water utility scientists, research water pollution microbiologists environmental health officers, consultants in communicable disease control and microbial water pollution students. Focuses on the microorganisms of most significance to public health, including E. coli, cryptosporidium, and enterovirus Highlights the basic microbiology, clinical features, survival in the environment, and gives a risk assessment for each pathogen Contains new material on antimicrobial resistance and biofilms Covers drinking water and both marine and freshwater recreational bathing waters

Helicobacter pylori
Helicobacter pylori

Author: R.H. Hunt

Publisher: Springer

Published: 2012-10-28

Total Pages: 612

ISBN-13: 9789401046206

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Helicobacter pylori has attracted widening interest from basic scientists and clinical investigators and the information on this organism is increasing exponentially. It is now accepted that H. Pylori is the most important cause of chronic active gastritis. Furthermore, data have confirmed a marked reduction in the relapse rate of both duodenal and gastric ulcer after eradication of the organism. These important clinical observations have served as a strong stimulus to the investigation of the basic mechanisms involved in the pathogenesis of H. pylori-associated inflammation and the subsequent alterations of gastroduodenal function and gastric mucosal architecture. The book contains chapters by a multidisciplinary, international group of basic scientists and clinical investigators who focus on various microbiological aspects of H. pylori, on the role of H. pylori in peptic ulcer and gastric cancer, and the current status of therapy. The book contains the proceedings of the conference on `Helicobacter pylori: Basic Mechanisms to Clinical Cure', held at Amelia Island, Florida, U.S.A., on November 3--6, 1993.

Vascular Responses to Pathogens
Vascular Responses to Pathogens

Author: Felicity N.E. Gavins

Publisher: Academic Press

Published: 2015-10-31

Total Pages: 254

ISBN-13: 0128013257

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Vascular Responses to Pathogens focuses on the growing research from leaders in the field for both the short and long-term impact of pathogens on the vasculature. It discusses various organisms, including bacteria, parasites, and viruses, and their role in key events leading to vascular disease. Formatted to discuss the topic of the interaction of pathogens with the vascular rather than individual diseases described separately, this reference demonstrates that common mechanisms are at play in many different diseases because they have a similar context, their vasculature. This all-inclusive reference book is a must-have tool for researchers and practicing clinicians in the areas of vascular biology, microvasculature, cardiology, and infectious disease. Covers a wide spectrum of organisms and provides analysis of pathogens and current therapeutic strategies in the context of their vasculature Provides detailed perspectives on key components contributing to vascular pathogens from leaders in the field Interfaces between both vascular biology and microbiology by encompassing information on how pathogens affect both macro and microvasculature Includes coverage of the clinical aspects of sepsis and current therapeutic strategies and anti-sepsis drugs

Helicobacter Pylori in Human Diseases
Helicobacter Pylori in Human Diseases

Author: Emma O'Neill

Publisher: American Medical Publishers

Published: 2021-11-16

Total Pages: 217

ISBN-13: 9781639271429

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Helicobacter pylori is a gram-negative microaerophilic bacterium that is found in the stomach. It is associated with gastric ulcers, chronic gastritis, duodenal ulcers and stomach cancer. Almost 85% of the people infected by H. pylori do not experience symptoms and complications. Acute cases of infection may present themselves as an acute gastritis with nausea or abdominal pain. These symptoms may progress into chronic gastritis, nonulcer dyspepsia, nausea, stomach pains, bloating, belching and black stool. Infection with H. pylori is also associated with colorectal cancer and colorectal polyps. The testing for H. pylori may be done using both invasive and non-invasive methods. Stool antigen tests, blood antibody tests, carbon urea breath tests and endoscopic biopsy are the methods for detecting infections with H. pylori. Rising antibiotic resistance has also increased the demand for alternate therapeutic strategies, such as vaccinations. The standard first-line therapy for H. pylori infections consist of proton-pump inhibitors and antibiotics. This book includes some of the vital pieces of work being conducted across the world, on various topics related to Helicobacter pylori infection. It provides significant information on H. pylori to help develop a good understanding of its role in human diseases. The book is appropriate for students seeking detailed information in this domain as well as for experts.

Missing Microbes
Missing Microbes

Author: Martin J. Blaser, MD

Publisher: Henry Holt and Company

Published: 2014-04-08

Total Pages: 289

ISBN-13: 0805098119

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“In Missing Microbes, Martin Blaser sounds [an] alarm. He patiently and thoroughly builds a compelling case that the threat of antibiotic overuse goes far beyond resistant infections.”—Nature Renowned microbiologist Dr. Martin J. Blaser invites us into the wilds of the human microbiome, where for hundreds of thousands of years bacterial and human cells have existed in a peaceful symbiosis that is responsible for the equilibrium and health of our bodies. Now this invisible Eden is under assault from our overreliance on medical advances including antibiotics and caesarian sections, threatening the extinction of our irreplaceable microbes and leading to severe health consequences. Taking us into the lab to recount his groundbreaking studies, Blaser not only provides elegant support for his theory, he guides us to what we can do to avoid even more catastrophic health problems in the future. “Missing Microbes is science writing at its very best—crisply argued and beautifully written, with stunning insights about the human microbiome and workable solutions to an urgent global crisis.”—David M. Oshinsky, author of the Pulitzer Prize-winning Polio: An American Story