Laboratory animal testing provides most of our current knowledge of human physiology, microbiology, immunology, pharmacology, and pathology. From studies of genetics in fruit flies to studies of cellular processes in genetically modified mice to recent dramatic developments in genetics, translational research, and personalized medicines, biomedical
Building upon the success of previous editions of the bestselling Handbook of Laboratory Animal Science, first published in 1994, this latest revision combines all three volumes in one definitive guide. It covers the essential principles and practices of Laboratory Animal Science as well as selected animal models in scientific disciplines where much progress has been made in recent years. Each individual chapter focuses on an important subdiscipline of laboratory animal science, and the chapters can be read and used as stand-alone texts, with only limited necessity to consult other chapters for information. With new contributors at the forefront of their fields, the book reflects the scientific and technological advances of the past decade. It also responds to advances in our understanding of animal behavior, emphasizing the importance of implementing the three Rs: replacing live animals with alternative methods, reducing the number of animals used, and refining techniques to minimize animal discomfort. This fourth edition will be useful all over the world as a textbook for laboratory animal science courses for postgraduate and undergraduate students and as a handbook for scientists who work with animals in their research, for university veterinarians, and for other specialists in laboratory animal science.
This bestseller has been an essential book for all those working with laboratory animals since it was first published in 1994. This fourth edition retains all the classic features that have made it a must-have reference including emphasis on best practice in order to improve animal welfare. The contents have been thoroughly updated and reorganised to make sure it is a really practical book for day-to-day use in the laboratory. The first section of the book covers principles applicable to all species, for example husbandry, handling and the education and training required by scientists and technical staff working with animals in the laboratory. Later chapters focus on specific species or groups of species. New to this edition: • Reflects changes in European legislation and their impact on national legislation • Covers recommendations for the education and training of those carrying out animal experiments across Europe • New chapters on ethical considerations and balancing animal welfare with science • New information on environmental enrichment for laboratory animals • Covers advancements in anaesthesia and analgesia and techniques • Spiral bound for ease-of-use as a bench-top reference This book is ideal for all personnel carrying out scientific procedures using animals, particularly during training and also for the new researcher. It will also be essential reading for study directors designing research programmes, animal technicians and veterinarians working with laboratory animal species.
While replacing and reducing the use of laboratory animals are integral parts of the 3Rs-replace, reduce, refine-which form the cornerstones of laboratory animal science, biomedical research involving animals remains absolutely essential for the advancement of the medical, veterinary, agricultural, and biological sciences. Building upon the bestsel
Biomedical research involving animals remains essential for the advancement of the medical, veterinary, agricultural, and biological sciences. Following in the footsteps of its predecessors, the Handbook of Laboratory Animal Science, Volume II, Third Edition: Animal Models explains in great detail the comparative considerations underlying the choic
The second edition of an international bestseller, this book provides veterinary specialists as well as veterinary and biomedical researchers with detailed information about laboratory animal genetics, diseases, health monitoring, nutrition, and environmental impact on animal experiments. Completely revised and updated, Volume I now contains expand
The seminal reference on the care of laboratory and captiveanimals, The UFAW Handbook on the Care and Management ofLaboratory and Other Research Animals is a must-have for anyoneworking in this field. The UFAW Handbook has been thedefinitive text since 1947. Written for an international audience,it contains contributions from experts from around the world. The book focuses on best practice principles throughout, providingcomprehensive coverage, with all chapters being peer reviewed byanonymous referees. As well as addressing the husbandry oflaboratory animals, the content is also of great value to zoos andaquaria. Changes for the eighth edition: Revised and updated to reflect developments since publicationof the previous edition. New chapters on areas of growing concern, including: the 3Rs;phenotyping; statistics and experimental design; welfareassessment; legislation; training of people caring for lab animals;and euthanasia. All material combined into one volume for ease ofreference. This book is published on behalf of UFAW (The UniversitiesFederation for Animal Welfare), with whom we also publish theUFAW/Wiley-Blackwell Animal Welfare Book Series. This majorseries of books provides an authoritative source ofinformation on worldwide developments, current thinking and bestpractice in the field of animal welfare science and technology. Fordetails of all of the titles in the series see ahref="http://www.wiley.com/go/ufaw"www.wiley.com/go/ufaw/a.
Laboratory animals are becoming increasingly important for biomedical research. It is said that approximately 70% of biomedical research is associated with the use of experimental animals. Laboratory animal research not only expands our knowledge of science, but also greatly improves human and animal health. The field of laboratory animal science is ever-growing and changing as new experimental techniques are developed and new animal models are created. It is essential to know not only the biological features of each laboratory animal but also how to use and care for them responsibly in order to perform high-quality experiments. Courses in beginning Laboratory Animal Science are starting to be offered in many universities throughout the world. However, a practical introductory textbook that contains state-of-the-art techniques is still lacking. Fundamentals of Laboratory Animal Science provides comprehensive information on the principles and practices of using laboratory animals for biomedical research. Each individual chapter focuses on a key sub-discipline of laboratory animal science: animal welfare and best humane care practices in the laboratory; the quality control of laboratory animals; the anatomy, physiology, and husbandry of commonly used species; the principles of creating and using animal models for studying human diseases; practical techniques used for laboratory animal experiments; experimental design; and animal experimentation management. Knowledge of this broad spectrum of concepts and skills will ensure research goes smoothly while greatly reducing animal pain and distress. Well-illustrated and thoroughly referenced, this book will serve not only as a standard textbook but also as a handy guide for veterinarians, researchers, animal care staff, administrators, and other professionals who are involved in laboratory animal science.
The Laboratory Mouse, Second Edition is a comprehensive book written by international experts. With inclusions of the newly revised European standards on laboratory animals, this will be the most current, global authority on the care of mice in laboratory research. This well-illustrated edition offers new and updated chapters including immunology, viruses and parasites, behavior, enrichment and care standards of laboratory mice across the life sciences, medical and veterinary fields. - Features four-color illustrations with complete instruction on mouse surgery, anatomy, behavior and care of the mouse in laboratory research - Offers additional chapters on new mouse strains, phenotyping of strains, bacteria and parasites, and immunology - Includes the newly revised EU standards on care, as well as, comparisons to standards and regulations in the US and other countries
The Handbook of Laboratory Animal Bacteriology, Second Edition provides comprehensive information on all bacterial phylae found in laboratory rodents and rabbits to assist managers, veterinary pathologists and laboratory animal veterinarians in the management of these organisms. The book starts by examining the general aspects of bacteriology and h
