Safety Assessment of Cosmetics in Europe

Safety Assessment of Cosmetics in Europe

Author: Vera Rogiers

Publisher: Karger Medical and Scientific Publishers

Published: 2008

Total Pages: 235

ISBN-13: 3805586558

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This volume of Current Problems in Dermatology presents the reader with a portrait of the scientific background of the complex process of safety assessment of cosmetics as well as information on European cosmetic legislation. A practical approach to the search for toxicity data on cosmetic ingredients and a compilation of the legally required technical dossier of a finished cosmetic product as well as an in-depth analysis of the safety assessment of cosmetic ingredients performed at the EU level by the Scientific Committee on Consumer Products (SCCP) are available. The current status of 3R alternatives to animal testing and the extent to which they are implemented by the cosmetic industry and considered by the SCCP in the risk assessment process is discussed. As such, guidance is provided in relation to the manifold challenges cosmetic safety assessors are faced with in the current EU regulatory setting.In this valuable handbook, qualified cosmetic safety assessors, suppliers of raw materials, dermatologists and pharmacists, toxicologists as well as EU officials and administrators dealing with cosmetics will find relevant information on the European cosmetic legislation, the compilation of cosmetic technical dossiers, toxicological database searches, and the availability and use of alternative methods in the field of cosmetics.


Toxicological Risk Assessment of Chemicals

Toxicological Risk Assessment of Chemicals

Author: Elsa Nielsen

Publisher: CRC Press

Published: 2008-02-21

Total Pages: 450

ISBN-13: 1420006940

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Unlike many existing books on toxicology that cover either toxicity of a particular substance or toxicity of chemicals on particular organ systems, Toxicological Risk Assessment of Chemicals: A Practical Guide lays out the principle activities of conducting a toxicological risk assessment, including international approaches and methods for the risk


Cancer Epidemiology and Prevention

Cancer Epidemiology and Prevention

Author: David Schottenfeld

Publisher: Oxford University Press

Published: 2006-08-24

Total Pages: 1411

ISBN-13: 0195149610

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Drawing widely from international sources, the new edition of this reference book on cancer causes, incidence, mortality and survival patterns, also includes chapters on social class, obesity, physical activity and chemoprevention plus other related topics in the field.


Cancer Epidemiology and Prevention

Cancer Epidemiology and Prevention

Author: Michael Thun

Publisher: Oxford University Press

Published: 2017-11-07

Total Pages: 1329

ISBN-13: 0190238682

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"The definitive reference for budding and experienced cancer epidemiologists alike." -American Journal of Epidemiology "Practitioners in epidemiology and oncology will find immense value in this." -JAMA Since its initial publication in 1982, CANCER EPIDEMIOLOGY AND PREVENTION has served as the premier reference work for students and professionals working to understand the causes and prevention of cancer in humans. Now revised for the first time in more than a decade, this fourth edition provides a comprehensive summary of the global patterns of cancer incidence and mortality, current understanding of the major causal determinants, and a rationale for preventive interventions. Special attention is paid to molecular epidemiologic approaches that address the wider role of genetic predisposition and gene-environment interactions in cancer etiology and pathogenesis. New and timely chapters on environmental and social-epidemiologic factors include: · The role of social class disparities · The role of obesity and physical inactivity · The potential effects of electromagnetic fields and radiofrequency radiation · The principles of cancer chemoprevention For both seasoned professionals and newer generations of students and researchers, this fourth edition of CANCER EPIDEMIOLOGY AND PREVENTION remains the authority in the field -- a work of distinction that every lab, library, student, professional, or researcher should have close at hand.


Cancer-gate

Cancer-gate

Author: Samuel S. Epstein

Publisher: Baywood Publishing Company, Inc.

Published: 2005

Total Pages: 408

ISBN-13: 9780895033109

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"Finally, Cancer-Gate tells you, the reader, how to fight back by arming yourself with the information you need to protect your family from everyday carcinogens, and how to become an activist in the war against cancer."--Jacket.


The Scientific Basis of Tobacco Product Regulation

The Scientific Basis of Tobacco Product Regulation

Author: World Health Organization

Publisher: World Health Organization

Published: 2008

Total Pages: 290

ISBN-13: 9241209518

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This report makes available the findings of an international group of experts that provide WHO with the latest scientific and technical advice in the area of product regulation. This second report presents policy recommendations on the topics of: smokeless tobacco products and their health effects, and implications for harm reduction and research needs; "fire safer" cigarettes and approaches to reduced ignition propensity; mandated lowering of toxicants in cigarette smoke, such as tobacco specific nitrosamines and other constituents; and, cigarette machine smoking regimens. The Study Group intends this new set of recommendations to be useful to WHO Member States, and national policymakers and regulators in shaping tobacco control policy.


Principles for Modelling Dose-response for the Risk Assessment of Chemicals

Principles for Modelling Dose-response for the Risk Assessment of Chemicals

Author: World Health Organization

Publisher: World Health Organization

Published: 2009

Total Pages: 164

ISBN-13: 9241572396

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"Published under the joint sponsorship of the United Nations Environment Programme, the International Labour Organisation and the World Health Organization, and produced within the framework of the Inter-Organization Programme for the Sound Management of Chemicals."


Biological Reactive Intermediates Vi

Biological Reactive Intermediates Vi

Author: Patrick Dansette

Publisher: Springer Science & Business Media

Published: 2001-11-30

Total Pages: 748

ISBN-13: 9780306466595

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This volume presents a discussion of the biological effects produced following the metabolism of xenobiotic chemicals to chemically reactive metabolites, that is, toxic and carcinogenic effects, which have been the basis of all five earlier volumes in this series. In particular, this volume devotes sections to structure-activity relationships, advances in the understanding of the chemistry of reactive metabolites, and the generation and activity of reactive oxygen species with special emphasis on nitric oxide. There are also segments on DNA damage by reactive metabolites and DNA repair, tissue specific responses to BRIs, and human health effects of BRIs. The papers that comprise this volume were submitted by scientists who were in attendance at The Symposium on Biological Reactive Intermediates VI at the Universite Rene Descartes, July 16-20, 2000.


Schottenfeld and Fraumeni Cancer Epidemiology and Prevention

Schottenfeld and Fraumeni Cancer Epidemiology and Prevention

Author: Michael J. Thun

Publisher: Oxford University Press

Published: 2018

Total Pages: 1329

ISBN-13: 0190238666

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"The definitive reference for budding and experienced cancer epidemiologists alike." -American Journal of Epidemiology "Practitioners in epidemiology and oncology will find immense value in this." -JAMA Since its initial publication in 1982, CANCER EPIDEMIOLOGY AND PREVENTION has served as the premier reference work for students and professionals working to understand the causes and prevention of cancer in humans. Now revised for the first time in more than a decade, this fourth edition provides a comprehensive summary of the global patterns of cancer incidence and mortality, current understanding of the major causal determinants, and a rationale for preventive interventions. Special attention is paid to molecular epidemiologic approaches that address the wider role of genetic predisposition and gene-environment interactions in cancer etiology and pathogenesis. New and timely chapters on environmental and social-epidemiologic factors include: - The role of social class disparities - The role of obesity and physical inactivity - The potential effects of electromagnetic fields and radiofrequency radiation - The principles of cancer chemoprevention For both seasoned professionals and newer generations of students and researchers, this fourth edition of CANCER EPIDEMIOLOGY AND PREVENTION remains the authority in the field -- a work of distinction that every lab, library, student, professional, or researcher should have close at hand.