Guideline for Preventive Chemotherapy for the Control of Taenia Solium Taeniasis
Guideline for Preventive Chemotherapy for the Control of Taenia Solium Taeniasis

Author: Pan American Health Organization

Publisher: Pan American Health Organization

Published: 2021-09-07

Total Pages: 0

ISBN-13: 9789275123713

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The larval stage of the parasite Taenia solium can encyst in the central nervous system causing neurocysticercosis, which is the main cause of acquired epilepsy in the countries in which the parasite is endemic. Endemic areas are those with the presence (or likely presence) of the full life cycle of Taenia solium. The parasite is most prevalent in poor and vulnerable communities in which pigs roam free, open defecation is practiced, basic sanitation is deficient, and health education is absent or limited. Several tools are available for the control of Taenia solium. Preventive chemotherapy for Taenia solium taeniasis, which is directed at the adult tapeworm, is one of them. Other tools focus on pig management, pig vaccination and treatment, sanitation and hygiene, and community education. Three potential drugs--niclosamide, praziquantel, and albendazole--have been considered for use for preventive chemotherapy in Taenia solium taeniasis control programs through mass drug administration or targeted chemotherapy. In this Guideline, we provide recommendations for preventive chemotherapy in Taenia solium-endemic areas using niclosamide, praziquantel, or albendazole, including at which dose and in which population groups. The development of this Guideline is based on the latest standard World Health Organization methods for guideline development, including the use of systematic search strategies, synthesis, quality assessment of the available evidence to support the recommendations, and participation of experts and stakeholders in the Guideline Development Group and External Review Group. The recommendations are intended for a wide audience, including policymakers and their expert advisers, and technical and program staff at governmental institutions and organizations involved in the planning, implementation, monitoring, and evaluation of preventive chemotherapy programs for the control of Taenia solium.

WHO guidelines on management of Taenia solium neurocysticercosis
WHO guidelines on management of Taenia solium neurocysticercosis

Author: World Health Organization

Publisher: World Health Organization

Published: 2021-09-03

Total Pages: 110

ISBN-13: 9240032231

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Taenia solium is a zoonotic tapeworm which causes taeniasis and cysticercosis in humans. The total number of people with symptomatic or asymptomatic neurocysticercosis is estimated to be 2.56-8.30 million from the data available. Incongruity among studies, however, demonstrates the extent to which neurocysticercosis remains an understudied, misunderstood, neglected tropical disease.

Early detection and management of neurological serious adverse events in relation to the administration of anthelminthic medicines to people with asymptomatic neurocysticercosis
Early detection and management of neurological serious adverse events in relation to the administration of anthelminthic medicines to people with asymptomatic neurocysticercosis

Author: World Health Organization

Publisher: World Health Organization

Published: 2023-09-18

Total Pages: 8

ISBN-13: 9240068139

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This document is designed for medical practitioners and programme staff working in preventive chemotherapy programs using praziquantel or multiple doses of albendazole in areas endemic or potentially endemic for T. solium. The objective of this document is to facilitate the training and awareness creation on the early identification of neurological serious adverse events and its management at the health centres. This is a derivative document from the PAHO/WHO Guideline for preventive chemotherapy for the control of T. solium taeniasis https://www.who.int/publications/i/item/9789275123720). It is based on the WHO mhGAP (https://www.who.int/publications/i/item/9789241549790) and complements the WHO publication on ‘Safety in administering medicines for neglected tropical diseases’ (https://www.who.int/publications/i/item/9789240024144). A poster has also been developed to accompany this document.

Microplanning manual to guide implementation of preventive chemotherapy to control and eliminate neglected tropical diseases
Microplanning manual to guide implementation of preventive chemotherapy to control and eliminate neglected tropical diseases

Author: World Health Organization

Publisher: World Health Organization

Published: 2022-09-05

Total Pages: 68

ISBN-13: 9240049487

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Neglected tropical diseases (NTDs) affect more than 1 billion people globally, causing serious, long-term health effects. Timely, effective interventions such as preventive chemotherapy, which involves the regular administration of safe, effective medicines to a defined population irrespective of its infection status, reduce morbidity and mortality. The new NTD road map advocates preventive chemotherapy as a core intervention to reduce the burden of NTDs. Effective administration of preventive chemotherapy relies largely on operational planning which addresses the need for programmes to reach all eligible people and maximize community demand for the intervention. Local, bottom-up planning (“microplanning”) fosters effective implementation and monitoring of public health programmes. Originally, public health implementers developed microplanning for use in vaccination campaigns, but various programmes, including those for control and elimination of NTDs, now use it. This manual is based on these and other country experiences in microplanning of preventive chemotherapy for NTDs. It describes the basic concepts of microplanning and provides steps and examples of tools to develop and implement a microplan. Since microplanning originates at the lowest level of implementation, and is a bottom-up process, the main target audience of this manual is individuals who are responsible for oversight of preventive chemotherapy against NTDs.

A compendium of indicators for monitoring and evaluating progress of the road map for neglected tropical diseases 2021–2030
A compendium of indicators for monitoring and evaluating progress of the road map for neglected tropical diseases 2021–2030

Author: World Health Organization

Publisher: World Health Organization

Published: 2023-01-06

Total Pages: 94

ISBN-13: 9240062866

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This compendium of indicators provides a comprehensive and standardized listing of recommended indicators, including the 70 core indicators presented in the M&E framework. These indicators will also support reporting on strategies described in other road map companion documents to guide action against neglectedtropical diseases include the sustainability framework, the global strategy on water, sanitation and hygiene, the One Health approach and the strategic framework for integrated control and elimination of skin-related neglected tropical diseases. The purpose of this compendium is to guide monitoring and evaluation of programmes and thereby to improve their quality and effectiveness in alignment with the road map goals. It provides a standardized listing of the most widely used indicators relevant to countries, with uniformity in defining indicators to allow comparisons over time and among different programmes. Detailed metadata are provided for each of these indicators to facilitate validity, internal consistency, standardized measurement, estimation methods and comparability of data across countries.

Global report on neglected tropical diseases 2023
Global report on neglected tropical diseases 2023

Author: World Health Organization

Publisher: World Health Organization

Published: 2023-01-30

Total Pages: 82

ISBN-13: 9240067299

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The Global report on neglected tropical diseases 2023 provides a consolidated, up-to-date assessment of progress towards control, elimination and eradication of 20 diseases and disease groups (NTDs) globally, regionally and nationally. Progress is reported in the context of global commitments, strategies and targets set in the NTD road map 2021-2030. The document covers the first two years of implementation of the road map (2021 and 2022). The information presented is based primarily on epidemiological and programmatic data for interventions conducted in 2021 and gathered in 2022, but the report also describes a wide range of activities and accomplishments that were registered in both 2021 and 2022; comparisons are often made against 2020 and 2019 data, especially with regard to COVID-19 disruptions. It has four sections: Section 1 is an introduction. Section 2 presents the status of the global NTD response. Section 3 charts progress and developments against the three road map pillars. Section 4 sets out priority actions for 2023 and beyond to sustain implementation of the road map and its companion documents. Five annexes to the report provide information for 2021–2022 on regional progress (Annex 1), Weekly Epidemiology Record articles on NTDs (Annex 2), progress and challenges by disease (Annex 3), diagnostic target product profiles (Annex 4) and the status of commitments for donated medicines and health products (Annex 5).

Rising Contagious Diseases
Rising Contagious Diseases

Author: Seth Kwabena Amponsah

Publisher: John Wiley & Sons

Published: 2024-01-24

Total Pages: 500

ISBN-13: 1394188714

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Comprehensive yet succinct insight into the prevention, diagnosis, and treatment of infectious diseases including COVID-19, mpox, Ebola, and Lyme disease Rising Contagious Diseases provides basic information about preventing and treating threatening infectious diseases from viral, bacterial, and parasitic sources, including 28 emerging or recurring diseases like COVID-19, mpox, Ebola, bird and swine flu, malaria, Legionnaires', and others. The text highlights molecular surveillance and epidemiology (including zoonotic pathogens or their variants), innovative strategies for pathogen detection, drug and vaccine development, appropriate preventive measures, cost-effective diagnostic procedures (assays), and effective therapeutic strategies. The text is unique due to its broad coverage of today's infectious diseases, covering several which are not similarly addressed elsewhere, with detailed insight from experts around the world. Composed of 30 chapters of fundamental facts alongside practical and clinical data, Rising Contagious Diseases covers sample topics such as: Re-emergence of certain diseases in recent decades due to dynamic host-pathogen interactions, anthropogenic selection, and climate change How real-time epidemiological surveillance can improve detection of infectious disease outbreaks or new infections of public health importance Up-to-date insight on transmission dynamics, epidemiology, clinical manifestation, advances in diagnostics, and management of covered diseases Effects of disease outbreaks on the world at large, such as through high morbidity and mortality rates and rising healthcare costs With detailed insight on the prevention, diagnosis, and treatment of infectious diseases, Rising Contagious Diseases is an essential reference for health care professionals, academics in the field of microbiology, immunology, infectious diseases, pathology, pharmacology and public health, and undergraduates and postgraduates in related disciplines.

Investing to Overcome the Global Impact of Neglected Tropical Diseases
Investing to Overcome the Global Impact of Neglected Tropical Diseases

Author: World Health Organization

Publisher: World Health Organization

Published: 2015-08-05

Total Pages: 211

ISBN-13: 9241564865

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"The presence, or absence, of neglected tropical diseases (NTDs) can be seen as a proxy for poverty and for the success of interventions aimed at reducing poverty. Today, coverage of the public-health interventions recommended by the World Health Organization (WHO) against NTDs may be interpreted as a proxy for universal health coverage and shared prosperity - in short, a proxy for coverage against neglect. As the world's focus shifts from development to sustainable development, from poverty eradication to shared prosperity, and from disease-specific goals to universal health coverage, control of NTDs will assume an important role towards the target of achieving universal health coverage, including individual financial risk protection. Success in overcoming NTDs is a "litmus test" for universal health coverage against NTDs in endemic countries. The first WHO report on NTDs (2010) set the scene by presenting the evidence for how these interventions had produced results. The second report (2013) assessed the progress made in deploying them and detailed the obstacles to their implementation. This third report analyses for the first time the investments needed to achieve the scale up of implementation required to achieve the targets of the WHO Roadmap on NTDs and universal coverage against NTDs. INVESTING TO OVERCOME THE GLOBAL IMPACT OF NEGLECTED TROPICAL DISEASES presents an investment strategy for NTDs and analyses the specific investment case for prevention, control, elimination and eradication of 12 of the 17 NTDs. Such an analysis is justified following the adoption by the Sixty-sixth World Health Assembly in 2013 of resolution WHA6612 on neglected tropical diseases, which called for sufficient and predictable funding to achieve the Roadmap's targets and sustain control efforts. The report cautions, however, that it is wise investment and not investment alone that will yield success. The report registers progress and challenges and signals those that lie ahead. Climate change is expected to increase the spread of several vector-borne NTDs, notably dengue, transmission of which is directly influenced by temperature, rainfall, relative humidity and climate variability primarily through their effects on the vector. Investments in vector-borne diseases will avoid the potentially catastrophic expenditures associated with their control. The presence of NTDs will thereby signal an early warning system for climate-sensitive diseases. The ultimate goal is to deliver enhanced and equitable interventions to the most marginalized populations in the context of a changing public-health and investment landscape to ensure that all peoples affected by NTDs have an opportunity to lead healthier and wealthier lives."--Publisher's description.