Global genomic surveillance strategy for pathogens with pandemic and epidemic potential, 2022-2032

Global genomic surveillance strategy for pathogens with pandemic and epidemic potential, 2022-2032

Author:

Publisher: World Health Organization

Published: 2022-03-23

Total Pages: 32

ISBN-13: 9240046976

DOWNLOAD EBOOK

The Global Genomic Surveillance Strategy for Pathogens with Pandemic and Epidemic Potential 2022-2032 provides a high-level unifying framework to leverage existing capacities, address barriers and strengthen the use of genomic surveillance in the detection, monitoring and response to public health threats. Genomic surveillance is part of the broader surveillance and laboratory system, and its implementation should reinforce end-to-end capacities including sample collection, diagnostics, data sharing and analysis. The strategy aims to facilitate the connectivity between different disease control programs and surveillance networks. This interoperability will strengthen the cross-cutting essential public health laboratory functions underpinning genomics holistically. The strategy articulates the overarching goal, objectives and strategic actions needed. These are dependent on commitments from countries, partners and WHO for their implementation.


Global genomic surveillance strategy for pathogens with pandemic and epidemic potential 2022-2032

Global genomic surveillance strategy for pathogens with pandemic and epidemic potential 2022-2032

Author: World Health Organization

Publisher: World Health Organization

Published: 2023-05-01

Total Pages: 26

ISBN-13: 9240057404

DOWNLOAD EBOOK

The Global Genomic Surveillance Strategy for Pathogens with Pandemic and Epidemic Potential 2022-2032 provides a high-level unifying framework to leverage existing capacities, address barriers and strengthen the use of genomic surveillance in the detection, monitoring and response to public health threats. Genomic surveillance is part of the broader surveillance and laboratory system, and its implementation should reinforce end-to-end capacities including sample collection, diagnostics, data sharing and analysis. The strategy aims to facilitate the connectivity between different disease control programs and surveillance networks. This interoperability will strengthen the cross-cutting essential public health laboratory functions underpinning genomics holistically. The strategy articulates the overarching goal, objectives and strategic actions needed. These are dependent on commitments from countries, partners and WHO for their implementation.


Considerations for developing a national genomic surveillance strategy or action plan for pathogens with pandemic and epidemic potential

Considerations for developing a national genomic surveillance strategy or action plan for pathogens with pandemic and epidemic potential

Author: World Health Organization

Publisher: World Health Organization

Published: 2023-08-18

Total Pages: 28

ISBN-13: 9240076565

DOWNLOAD EBOOK

Policy considerations to strengthen genomic surveillance for pathogens with pandemic and epidemic potential is a support tool that provides key consideration and a proposed stepwise approach for countries to develop a national genomic surveillance strategy or action plan for pathogens with pandemic and epidemic potential. This document is intended for use by all stakeholders at the national and subnational level relevant to the development and implementation of the strategy or action plan, including health authorities, One Health partners, donors, public health officers, academia, the private sector and laboratory specialists.


WHO benchmarks for strengthening health emergency capacities

WHO benchmarks for strengthening health emergency capacities

Author: World Health Organization

Publisher: World Health Organization

Published: 2024-01-25

Total Pages: 400

ISBN-13: 9240086765

DOWNLOAD EBOOK

The WHO Benchmarks for International Health Regulations (2005) (IHR) Capacities was first published in 2019 and serves as a capacity-building tool and reference document to guide development/updating of country health security plans, including the national action plan for health security (NAPHS). It is now updated to a second edition which incorporates lessons learned from recent health emergencies, as well as alignment with updated IHRMEF tools, the HEPR framework, the WHO Director-General’s ten proposals to build a safer world together, and to build back better through multi-hazard and whole-of-society approaches to support better preparedness for future emergencies. Over 250 relevant technical leads contributed to this edition, by providing inputs from WHO regional offices, countries, partners and participation in global consultation meetings. The second edition is titled “WHO Benchmarks for Strengthening Health Emergency Capacities: Support for the Implementation of International Health Regulations (IHR) and Health Emergency Prevention, Preparedness, Response and Resilience (HEPR) Capacities”. WHO benchmarks are further digitalized for easy and quick use, along with a reference library, which is currently being updated. The audience for this document includes WHO Member States, health ministries and other relevant ministries, healthstakeholders, partners, nongovernmental organizations and academia to support building capacities at the country level.


Genomic Surveillance and Pandemic Preparedness

Genomic Surveillance and Pandemic Preparedness

Author: Rajesh Pandey

Publisher: Elsevier

Published: 2023-06-29

Total Pages: 428

ISBN-13: 0443187681

DOWNLOAD EBOOK

Genomic Surveillance and Pandemic Preparedness offers practical, in-depth instruction in where, how, and why genomic surveillance may be applied. Drawing heavily from the learnings during the COVID-19 pandemic, this book covers different aspects of microbes with a focus on viral genome sequencing and analysis, implementation and inference of genomic surveillance, and global data sharing best practices for future pandemic preparedness. Here, more than a dozen international authors consider host and pathogen genome interaction, population-level prevalence, individual disease susceptibility and gene protection, pathogen mutation evolutionary dynamics, RNA modulation of infection, pathogen diversity, and the role of coinfections and comorbidities in disease severity. A wide range of examples, from bacterial pathogens to fungal and viral infections, with an emphasis on recent COVID-19 analysis, are discussed. Finally, the authors provide step-by-step instruction in experimental and computational approaches for genomic surveillance, including nucleic acid isolation, sequencing library preparation, functional sequencing analysis, and bioinformatics pipelines. Throughout this book, importance is placed on inference—moving from genomic sequencing to meaningful genomic surveillance that bolsters pandemic preparedness. - Highlights different aspects of genomic surveillance, from theory to implementation to inferences - Covers a broad range of infectious diseases, with emphasis on recent COVID-19 studies - Shares methods and approaches for sequencing-based pathogen detection, diagnostics, and surveillance - Facilitates international collaboration in drug and vaccine development


WHO’s response to health emergencies

WHO’s response to health emergencies

Author: World Health Organization

Publisher: World Health Organization

Published: 2023-05-22

Total Pages: 65

ISBN-13: 9240074643

DOWNLOAD EBOOK

This report provides highlights from WHO’s response to health emergencies during 2022. It outlines the increasingly critical role of WHO at global, regional and country levels, and across the key elements of effective emergency response, including emergency coordination and planning, operational and logistic support, and community engagement and protection. The huge scale and complexities of health emergencies in the 21st century require a strategic shift towards not only meeting the immediate needs of vulnerable communities, but also building community and health system resilience to all hazards – a challenge that both WHO and its partners must continue to meet.


Genomics, Populations, and Society

Genomics, Populations, and Society

Author: Dhavendra Kumar

Publisher: Elsevier

Published: 2024-12-01

Total Pages: 448

ISBN-13: 0323971997

DOWNLOAD EBOOK

Genomics, Populations, and Society, a new volume in the Genomic and Precision Medicine in Clinical Practice series, considers the vast and thorny web of ELSI topics in genomics, from bioethics to healthcare applications, healthcare economics, genomic data management, and population dynamics. Emphasis is placed on the impact of rapid genomic advances on ethical, sociocultural and lifestyle dimensions. Healthcare and health economics topics include genomics and digital health, genome editing, and genomics and infectious disease management. Legal issues related to data ownership, equity, access, probity, consent, and confidentiality are also discussed in-depth, along with sociocultural topics such as community engagement, consanguinity, and more.Here, a range of readers from researchers to clinicians, policy administrators, lawyers, economists and social scientists will discover carefully crafted, synthesized discussions on ELSI topics in genomics to power new scientific advances and genomic medicine implementation. - Includes more than twenty-four chapters across five integrated sections on scientific dilemmas in genomics, genomic healthcare applications, sociocultural aspects of genomics, ethical aspects and global health genomics - Presents fundamental issues tied to biosociety, healthcare, law, and the bioeconomy as genomic medicine moves from research lab to the clinic - Features chapter contributions from international experts