Functioning of Transmembrane Receptors in Signaling Mechanisms

Functioning of Transmembrane Receptors in Signaling Mechanisms

Author: Ralph A. Bradshaw

Publisher: Academic Press

Published: 2011-04-05

Total Pages: 459

ISBN-13: 0123822122

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A primary component of cell signaling research, this title covers the principal membrane-bound receptor families, including their structural organization. Written and edited by experts in the field, this book provides up-to-date research on transmembrane signaling entities and their initiating responses following extracellular stimulation. Articles written and edited by experts in the field Thematic volume covering effectors, cytosolic events, nuclear, and cytoplasmic events Up-to-date research on signaling systems and mutations in transcription factors that provide new targets for treating disease


Encyclopedia of Molecular Pharmacology

Encyclopedia of Molecular Pharmacology

Author: Stefan Offermanns

Publisher: Springer Science & Business Media

Published: 2008-08-14

Total Pages: 1515

ISBN-13: 3540389164

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An essential text, this is a fully updated second edition of a classic, now in two volumes. It provides rapid access to information on molecular pharmacology for research scientists, clinicians and advanced students. With the A-Z format of over 2,000 entries, around 350 authors provide a complete reference to the area of molecular pharmacology. The book combines the knowledge of classic pharmacology with the more recent approach of the precise analysis of the molecular mechanisms by which drugs exert their effects. Short keyword entries define common acronyms, terms and phrases. In addition, detailed essays provide in-depth information on drugs, cellular processes, molecular targets, techniques, molecular mechanisms, and general principles.


Endothelin Receptors and Signaling Mechanisms

Endothelin Receptors and Signaling Mechanisms

Author: David M. Pollock

Publisher: Springer Science & Business Media

Published: 2013-03-09

Total Pages: 377

ISBN-13: 3662116723

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This book focuses on the wide variety of intracellular events that occur as a result of endothelin receptor activation. This includes a discussion of the various pathways by which endothelin activates Ca2+ signals from several intra- and extracellular sources and the effects of endothelin on ion channels and membrane function. In addition, the mechanisms by which endothelin influences the ion transport within the renal epithelium are covered, as well as the signal transduction pathways activated by endothelin in both cardiac tissue and vascular smooth muscle.


Neuromorphic Olfaction

Neuromorphic Olfaction

Author: Krishna C. Persaud

Publisher: CRC Press

Published: 2016-04-19

Total Pages: 237

ISBN-13: 1439871728

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Many advances have been made in the last decade in the understanding of the computational principles underlying olfactory system functioning. Neuromorphic Olfaction is a collaboration among European researchers who, through NEUROCHEM (Fp7-Grant Agreement Number 216916)-a challenging and innovative European-funded project-introduce novel computing p


TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades

TRP Ion Channel Function in Sensory Transduction and Cellular Signaling Cascades

Author: Wolfgang B. Liedtke, MD, PH.D.

Publisher: CRC Press

Published: 2006-09-29

Total Pages: 502

ISBN-13: 1420005847

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Since the first TRP ion channel was discovered in Drosophila melanogaster in 1989, the progress made in this area of signaling research has yielded findings that offer the potential to dramatically impact human health and wellness. Involved in gateway activity for all five of our senses, TRP channels have been shown to respond to a wide range of st


Biochemistry of Signal Transduction and Regulation

Biochemistry of Signal Transduction and Regulation

Author: Gerhard Krauss

Publisher: John Wiley & Sons

Published: 2006-03-06

Total Pages: 558

ISBN-13: 3527605762

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This all-new edition of a classic text has been thoroughly revised to keep pace with the rapid progress in signal transduction research. With didactic skill and clarity the author relates the observed biological phenomena to the underlying biochemical processes. Directed to advanced students, teachers, and researchers in biochemistry and molecular biology, this book describes the molecular basis of signal transduction, regulated gene expression, the cell cycle, tumorigenesis and apoptosis. "Provides a comprehensive account of cell signaling and signal transduction and, where possible, explains these processes at the molecular level" (Angewandte Chemie) "The clear and didactic presentation makes it a textbook very useful for students and researchers not familiar with all aspects of cell regulation." (Biochemistry) "This book is actually two books: Regulation and Signal Transduction." (Drug Research)


Signal Transduction: Pathways, Mechanisms and Diseases

Signal Transduction: Pathways, Mechanisms and Diseases

Author: Ari Sitaramayya

Publisher: Springer Science & Business Media

Published: 2009-12-02

Total Pages: 429

ISBN-13: 3642021123

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Providing an overview of recent developments in the field of signal transduction, this volume emphasizes direct clinical significance. As such, topics like nuclear receptors, apoptosis, growth factors, cell cycles and cancer are examined.


Neurotrophic Factors

Neurotrophic Factors

Author: Gary R. Lewin

Publisher: Springer Science & Business Media

Published: 2014-03-25

Total Pages: 514

ISBN-13: 3642451063

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This book provides critical reviews of the role of neurotrophins and their receptors in a wide variety of diseases including neurodegenerative diseases like Huntington’s syndrome, cognitive function, psychiatric disorders such as clinical depression, Rett syndrome, motoneurone disease, spinal cord injury, pain, metabolic disease and cardiovascular disease. It also contains contributions from leaders in the field dealing with the basic biology, transcriptional and post-translational regulation of the neurotrophins and their receptors. The present book will review all recent areas of progress in the study of neurotrophins and their biological roles.


G-Protein Coupled Transmembrane Signaling Mechanisms

G-Protein Coupled Transmembrane Signaling Mechanisms

Author: Robert R. Ruffolo

Publisher: CRC Press

Published: 1995-01-09

Total Pages: 220

ISBN-13:

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This book discusses recent major advances made in the molecular biology, signal transduction processes, pharmacology, and therapeutic applications of key receptors and receptor systems.