Functional Metagenomics: Tools and Applications

Functional Metagenomics: Tools and Applications

Author: Trevor C. Charles

Publisher: Springer

Published: 2017-10-09

Total Pages: 256

ISBN-13: 3319615106

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In this book, the latest tools available for functional metagenomics research are described.This research enables scientists to directly access the genomes from diverse microbial genomes at one time and study these “metagenomes”. Using the modern tools of genome sequencing and cloning, researchers have now been able to harness this astounding metagenomic diversity to understand and exploit the diverse functions of microorganisms. Leading scientists from around the world demonstrate how these approaches have been applied in many different settings, including aquatic and terrestrial habitats, microbiomes, and many more environments. This is a highly informative and carefully presented book, providing microbiologists with a summary of the latest functional metagenomics literature on all specific habitats.


The New Science of Metagenomics

The New Science of Metagenomics

Author: National Research Council

Publisher: National Academies Press

Published: 2007-06-24

Total Pages: 170

ISBN-13: 0309106761

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Although we can't usually see them, microbes are essential for every part of human life-indeed all life on Earth. The emerging field of metagenomics offers a new way of exploring the microbial world that will transform modern microbiology and lead to practical applications in medicine, agriculture, alternative energy, environmental remediation, and many others areas. Metagenomics allows researchers to look at the genomes of all of the microbes in an environment at once, providing a "meta" view of the whole microbial community and the complex interactions within it. It's a quantum leap beyond traditional research techniques that rely on studying-one at a time-the few microbes that can be grown in the laboratory. At the request of the National Science Foundation, five Institutes of the National Institutes of Health, and the Department of Energy, the National Research Council organized a committee to address the current state of metagenomics and identify obstacles current researchers are facing in order to determine how to best support the field and encourage its success. The New Science of Metagenomics recommends the establishment of a "Global Metagenomics Initiative" comprising a small number of large-scale metagenomics projects as well as many medium- and small-scale projects to advance the technology and develop the standard practices needed to advance the field. The report also addresses database needs, methodological challenges, and the importance of interdisciplinary collaboration in supporting this new field.


Functional Metagenomics

Functional Metagenomics

Author: Maulin P. Shah

Publisher: Elsevier

Published: 2023-11-09

Total Pages: 246

ISBN-13: 0323986439

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Functional Metagenomics: Microbial Diversity, Interaction, and Application in Bioremediation uses a 20-chapter, easy-to-understand format to centralize the practical application ideas for functional metagenomics. This important resource not only includes chapters on next-generation sequencing technologies to study important biogeochemical cycles, degradation pathways and detoxification, but also gives insight into several tools that have been developed to integrate metadata and sequence data, allowing downstream comparative analyses of different datasets using several ecological indices.Content further explains the newly developed techniques for sequencing DNA; generating shorter fragments than Sanger sequencing techniques to quickly read larger sequences in a shorter amount of time. The content finally explores the role of metagenomics in studying microbial diversity, interaction and application in bioremediation studies and gives the reader overall detailed information regarding metagenomics, its application as well as techniques. - Provides comprehensive information to readers on state-of-the-art applications in metagenomics - Summarizes our current knowledge of the use of metagenomics and gives a novel and powerful insight into the already existing bioremediation process - Gives an overall picture of metagenomics, its application, processes, and future prospects in the field of bioremediation


Introduction To Computational Metagenomics

Introduction To Computational Metagenomics

Author: Zhong Wang

Publisher: World Scientific

Published: 2022-04-11

Total Pages: 210

ISBN-13: 9811242488

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Breakthroughs in high-throughput genome sequencing and high-performance computing technologies have empowered scientists to decode many genomes including our own. Now they have a bigger ambition: to fully understand the vast diversity of microbial communities within us and around us, and to exploit their potential for the improvement of our health and environment. In this new field called metagenomics, microbial genomes are sequenced directly from the habitats without lab cultivation. Computational metagenomics, however, faces both a data challenge that deals with tens of tera-bases of sequences and an algorithmic one that deals with the complexity of thousands of species and their interactions.This interdisciplinary book is essential reading for those who are interested in beginning their own journey in computational metagenomics. It is a prism to look through various intricate computational metagenomics problems and unravel their three distinctive aspects: metagenomics, data engineering, and algorithms. Graduate students and advanced undergraduates from genomics science or computer science fields will find that the concepts explained in this book can serve as stepping stones for more advanced topics, while metagenomics practitioners and researchers from similar disciplines may use it to broaden their knowledge or identify new research targets.


Phytomicrobiome Interactions and Sustainable Agriculture

Phytomicrobiome Interactions and Sustainable Agriculture

Author: Amit Verma

Publisher: John Wiley & Sons

Published: 2021-01-08

Total Pages: 320

ISBN-13: 111964481X

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A guide to the role microbes play in the enhanced production and productivity of agriculture to feed our growing population Phytomicrobiome Interactions and Sustainable Agriculture offers an essential guide to the importance of ‘Phytomicrobiome’ and explores its various components. The authors – noted experts on the topic – explore the key benefits of plant development such as nutrient availability, amelioration of stress and defense to plant disease. Throughout the book, the authors introduce and classify the corresponding Phytomicrobiome components and then present a detailed discussion related to its effect on plant development: controlling factors of this biome, its behaviour under the prevailing climate change condition and beneficial effects. The book covers the newly emerging technical concept of Phytomicrobiome engineering, which is an advanced concept to sustain agricultural productivity in recent climatic scenario. The text is filled with comprehensive, cutting edge data, making it possible to access this ever-growing wealth of information. This important book: Offers a one-stop resource on phytomicrobiome concepts Provides a better understanding of the topic and how it can be employed for understanding plant development Contains a guide to sustaining agriculture using phytomicrobiome engineering Presents information that can lead to enhanced production and productivity to feed our growing population Written for students, researchers and policy makers of plant biology, Phytomicrobiome Interactions and Sustainable Agriculture offers a clear understanding of the importance of microbes in overall plant growth and development.


Environmental Contaminants: Ecological Implications and Management

Environmental Contaminants: Ecological Implications and Management

Author: Ram Naresh Bharagava

Publisher: Springer Nature

Published: 2019-10-28

Total Pages: 348

ISBN-13: 9811379041

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As we know, rapid industrialization is a serious concern in the context of a healthy environment. Various physico-chemical and biological approaches for the removal of toxic pollutants are available, but unfortunately these are not very effective. Biological approaches using microorganisms (bacterial/fungi/algae), green plants or their enzymes to degrade/detoxify environmental contaminants such as endocrine disrupting chemicals, toxic metals, pesticides, dyes, petroleum hydrocarbons and phenolic compounds are eco-friendly and low cost. This book provides a much-needed, comprehensive overview of the various types of contaminants, their toxicological effects on the environment, humans, animals and plants as well as various eco-friendly approaches for their management (degradation/detoxification). As such it is a valuable resource for a wide range of students, scientists and researchers in microbiology, biotechnology, environmental sciences.


Microbiome Drivers of Ecosystem Function

Microbiome Drivers of Ecosystem Function

Author: Javid A. Parray

Publisher: Elsevier

Published: 2023-10-13

Total Pages: 490

ISBN-13: 044322398X

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Microbiome Drivers of Ecosystem Function focuses on the advancements in microbial technologies towards harnessing the microbiome for improved crop productivity and health that are at the frontier of agricultural sciences. It provides insights into the diversity of endophytic microbiomes and their potential utility in agricultural production.Increased crop yield through chemical interventions have limit thresholds and alternative, natural and/or integrated approaches are increasingly needed. Microbial inoculants among the ways in which food production efficiency can be improved. Plant growth-promoting soil organisms increase net crop uptake of soil nutrients, resulting in larger crops and higher yields of harvested food. These and other symbiotic associations between plants and microbes can ultimately be exploited for the increased food production necessary to feed the world, in addition to creating safer farming techniques that minimize ecological disruption.As a volume in the Microbiome Research in Plants and Soil series, Microbiome Drivers of Ecosystem Function serves as an ideal reference for researchers and students in the fields of agricultural biotechnology, biochemistry, environmental science, plant biology, agricultural sciences, and agricultural engineering. - Provides insights on engineered microbes in sustainable agriculture, recent biotechnological developments, and future prospects - Introduces microbes as chief ecological engineers in reinstating equilibrium in degraded ecosystems - Presents the current state and development, as well as future challenges in studying plant-microbe interactions - Discusses endophytic microbiomes and other microbial consortium with multifunctional plant growth-promoting attributes


Metagenomics

Metagenomics

Author: Muniyandi Nagarajan

Publisher: Academic Press

Published: 2024-11-05

Total Pages: 562

ISBN-13: 0323917127

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Metagenomics: Perspectives, Methods, and Applications, second edition, provides thorough coverage of the growing field of metagenomics. A diverse range of chapters from international experts offer an introduction to the field and examine methods for metagenomic analysis of microbiota, metagenomic computational tools, and recent metagenomic studies in various environments and clinical settings. The emphasis on application makes this text particularly useful for applied researchers, practitioners, clinicians, and students seeking to employ metagenomic approaches to advance knowledge in the biomedical and life sciences. Case study-based application chapters include topics ranging from metagenome tools, metagenomics in oral disease and health, metagenomic insights into the human gut microbiome and metabolic syndromes, and more. This new edition has been fully updated to address the rapid growth and development of metagenomics applications, featuring expert discussion of recent developments and fresh case studies. Newly added chapters instruct in methods and implications of metagenomics in areas of growing focus, such as microbiome research, clinical diagnosis, metagenomic epidemiology, and plant microbe interaction. Data analysis is explained in simple terms for effective use of computational tools, software, and sequencing pipelines. - Features a diverse range of chapters from international experts - Highlights current state-of-the-art and recent advances in the field with current perspectives and case studies - Includes methods, techniques, and various computational software tools and pipelines currently used in metagenomic studies - Provokes new thought and motivations for continued study, with next steps in research discussed at the end of each chapter


From Genes to Species: Novel Insights from Metagenomics

From Genes to Species: Novel Insights from Metagenomics

Author: Eamonn P. Culligan

Publisher: Frontiers Media SA

Published: 2016-10-07

Total Pages: 231

ISBN-13: 2889199754

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The majority of microbes in many environments are considered “as yet uncultured” and were traditionally considered inaccessible for study through the microbiological gold standard of pure culture. The emergence of metagenomic approaches has allowed researchers to access and study these microbes in a culture-independent manner through DNA sequencing and functional expression of metagenomic DNA in a heterologous host. Metagenomics has revealed an extraordinary degree of diversity and novelty, not only among microbial communities themselves, but also within the genomes of these microbes. This Research Topic aims to showcase the utility of metagenomics to gain insights on the microbial and genomic diversity in different environments by revealing the breadth of novelty that was in the past, largely untapped.