Frontiers in Clinical Drug Research - Anti Infectives: Volume 8
Frontiers in Clinical Drug Research - Anti Infectives: Volume 8

Author: Atta-ur-Rahman

Publisher: Bentham Science Publishers

Published: 2021-12-07

Total Pages: 367

ISBN-13: 9815039423

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Frontiers in Clinical Drug Research – Anti infectives is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. The scope of the book series covers a range of topics including the chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of infectious diseases. Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents. Frontiers in Clinical Drug Research – Anti infectives is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of anti infective drug discovery and epidemiology. The eighth volume of this series presents comprehensive reviews of interest to readers interested in the treatment of inflammatory diseases, new antiviral agents and strategies, specific antiprotozoal drugs that work against leishmania and helminths, and a study on potential agents against American foulbrood in honey bees. The 7 reviews included in this volume are: - Monoclonal antibodies as therapeutic agents for inflammatory diseases - Pharmacotherapy of emerging antiviral agents - Antiviral activity of vitamin D and COVID-19: current understanding - Anti-infectives to combat leishmaniasis - Anthelmintic drug discovery: current situation and future perspectives - Therapeutic targets for emerging Zika virus infection and vaccines in clinical trials - Agro-industrial waste: new source of raw material for the control of American foulbrood in honey bees.

Frontiers in Clinical Drug Research - Anti Infectives: Volume 5
Frontiers in Clinical Drug Research - Anti Infectives: Volume 5

Author: Atta-ur-Rahman

Publisher: Bentham Science Publishers

Published: 2019-06-11

Total Pages: 246

ISBN-13: 1681086387

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Frontiers in Clinical Drug Research – Anti infectives is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. The scope of the book series covers a range of topics including the chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of infectious diseases. Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents.Frontiers in Clinical Drug Research – Anti infectives is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of anti infective drug discovery and epidemiology. The fifth volume of this series features six reviews: - Integrated Approaches for Marine Actinomycete Biodiscovery - Therapeutic Use of Commensal Microbes: Fecal/Gut Microbiota Transplantation - Alternative Approaches to Antimicrobials - Nanoantibiotics: Recent Developments and Future - Cranberry Juice and Other Functional Foods in Urinary Tract Infections in Women: A Review of Actual Evidence and Main Challenges - Targeting Magnesium Homeostasis as Potential Anti-Infective Strategy Against Mycobacteria

Frontiers in Clinical Drug Research - Anti Infectives: Volume 7
Frontiers in Clinical Drug Research - Anti Infectives: Volume 7

Author: Atta-ur-Rahman

Publisher: Bentham Science Publishers

Published: 2021-07-02

Total Pages: 194

ISBN-13: 9814998109

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Frontiers in Clinical Drug Research – Anti infectives is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. The scope of the book series covers a range of topics including the chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of infectious diseases. Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents. Frontiers in Clinical Drug Research – Anti infectives is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of anti infective drug discovery and epidemiology. The seventh volume of this series features these interesting reviews: - Nucleic acid and peptide aptamers as potential antiviral drugs - Host-directed, antibiotic-adjuvant combination, and antibiotic-antibiotic combinations for treating multidrug-resistant (mdr) gram-negative pathogens - Bioactive substances as anti-infective strategies against clostridioides difficile - Anti-toxoplasma drug discovery and natural products: a brief overview - Development of antimalarial and antileishmanial drugs from amazonian biodiversity

Frontiers in Clinical Drug Research: Anti-Infectives
Frontiers in Clinical Drug Research: Anti-Infectives

Author: Atta-ur-Rahman

Publisher: Bentham Science Publishers

Published: 2014-06-30

Total Pages: 367

ISBN-13: 1608058549

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Frontiers in Clinical Drug Research – Anti Infectives is an eBook series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. The scope of the eBook series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of infectious diseases. Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents. Frontiers in Clinical Drug Research – Anti Infectives is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of anti infective drug discovery and epidemiology. The first volume of this series features reviews that cover a variety of topics including: -Bacteriophage research against gram positive bacteria -Edible vaccines -Novel antibiotics against gram negative bacteria -Antimicrobial resistance among enteric pathogens

Frontiers in Anti-Infective Drug Discovery: Volume 8
Frontiers in Anti-Infective Drug Discovery: Volume 8

Author: Atta-ur-Rahman

Publisher: Bentham Science Publishers

Published: 2020-10-05

Total Pages: 277

ISBN-13: 9811412375

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This book series brings updated reviews to readers interested in advances in the development of anti-infective drug design and discovery. The scope of the book series covers a range of topics including rational drug design and drug discovery, medicinal chemistry, in-silico drug design, combinatorial chemistry, high-throughput screening, drug targets, recent important patents, and structure-activity relationships. Frontiers in Anti-Infective Drug Discovery is a valuable resource for pharmaceutical scientists and post-graduate students seeking updated and critically important information for developing clinical trials and devising research plans in this field. The eighth volume of this series features 8 chapters that cover methods for antimicrobial drug discovery (with 2 chapters that focus on genomics) as well as updates on drug development against Helicobacter pylori and emerging coronaviruses, among other interesting topics: - Eradication of Helicobacter pylori Infection with Non-Bismuth Quadruple Concomitant Therapy - Drug Discovery Strategies Against Emerging Coronaviruses: A Global Threat - Opportunities Offered By Fragment-Based Drug Design in Antibiotic Development - Phage therapy as a Tool for Control of Foodborne Diseases: Advantages and Limitations - Subtractive Genomics Approaches: Towards Anti-Bacterial Drug Discovery - Recent Advances in the Discovery of Antimicrobials through Metagenomics - Phyto-Nano-Antimicrobials: Synthesis, Characterization, Discovery, and Advances - Aptamers as Anti-infective Agents.

Frontiers in Clinical Drug Research - Anti-Cancer Agents: Volume 8
Frontiers in Clinical Drug Research - Anti-Cancer Agents: Volume 8

Author: Atta-ur-Rahman

Publisher: Bentham Science Publishers

Published: 2021-12-03

Total Pages: 322

ISBN-13: 1681089327

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Frontiers in Clinical Drug Research - Anti-Cancer Agents is a book series intended for pharmaceutical scientists, postgraduate students and researchers seeking updated and critical information for developing clinical trials and devising research plans in anti-cancer research. Reviews in each volume are written by experts in medical oncology and clinical trials research and compile the latest information available on special topics of interest to oncology and pharmaceutical chemistry researchers. The eighth volume of the book features reviews on these topics: - Key data management elements in clinical trials for oncological therapeutics - Prospects for therapeutic targeting of microRNAs in brain tumors - Breast cancer vaccines: current status and future approach - Desmocollin-3 and cancer - MDM2-p53 antagonists under clinical evaluation: a promising cancer targeted therapy for cancer patients harbouring wild-type tp53 - Towards targeted therapy: anticancer agents targeting cell organelle mitochondria - Anticancer therapeutic strategies in gliomas: chemotherapy, immunotherapy, and molecularly targeted therapy in adults.

Frontiers in Clinical Drug Research - Anti Infectives: Volume 6
Frontiers in Clinical Drug Research - Anti Infectives: Volume 6

Author: Atta-ur-Rahman

Publisher: Bentham Science Publishers

Published: 2020-08-20

Total Pages: 229

ISBN-13: 9811425736

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Frontiers in Clinical Drug Research – Anti infectives is a book series that brings updated reviews to readers interested in learning about advances in the development of pharmaceutical agents for the treatment of infectious diseases. The scope of the book series covers a range of topics including the chemistry, pharmacology, molecular biology and biochemistry of natural and synthetic drugs employed in the treatment of infectious diseases. Reviews in this series also include research on multi drug resistance and pre-clinical / clinical findings on novel antibiotics, vaccines, antifungal agents and antitubercular agents. Frontiers in Clinical Drug Research – Anti infectives is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critically important information for developing clinical trials and devising research plans in the field of anti infective drug discovery and epidemiology. The sixth volume of this series features these interesting reviews: - Direct-acting antiviral drugs for treatment of Hepatitis C virus infection - Plant lattices as anti-infective compounds - Antimicrobial materials and devices for biomedical applications - Recent advances in the treatment of toxoplasmosis - Antimicrobial immunoglobulin prophylaxis and therapy - Targeting Magnesium Homeostasis as Potential Anti-Infective Strategy Against Mycobacteria

Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 9
Frontiers in Clinical Drug Research - CNS and Neurological Disorders: Volume 9

Author: Atta-ur-Rahman

Publisher: Bentham Science Publishers

Published: 2021-10-15

Total Pages: 279

ISBN-13: 168108905X

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Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a book series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the book series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of contemporary molecular targets involved in neurological and CNS disorders. Reviews presented in the series are mainly focused on clinical and therapeutic aspects of novel drugs intended for these targets. Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critical information for developing clinical trials and devising research plans in the field of neurology. The ninth volume of this series features reviews that cover the following topics related to the treatment of a different CNS disorders, related diseases and basic neuropharmacology research: - Integrating imaging and microdialysis into systems neuropharmacology - Depression heterogeneity and the potential of a transdiagnostic and dimensional approach to identify biologically relevant phenotypes - CAR-T cells in brain tumors and autoimmune diseases – from basics to the clinic - Revaluation of thyrotropin-releasing hormone and its mimetics as candidates for treating a wide range of neurological and psychiatric disorders - Natural BACE1 inhibitors: promising drugs for the management of Alzheimer’s disease - The possibilities of safe lithium therapy in the treatment of neurological and psychoemotional disorders - Pharmacotherapy of multiple sclerosis and treatment strategies

Frontiers in Clinical Drug Research - CNS and Neurological Disorders
Frontiers in Clinical Drug Research - CNS and Neurological Disorders

Author: Atta-ur-Rahman

Publisher: Bentham Science Publishers

Published: 2013-10-11

Total Pages: 373

ISBN-13: 1608057755

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Frontiers in Clinical Drug Research - CNS and Neurological Disorders is an ebook series that brings updated reviews to readers interested in advances in the development of pharmaceutical agents for the treatment of central nervous system (CNS) and other nerve disorders. The scope of the ebook series covers a range of topics including the medicinal chemistry, pharmacology, molecular biology and biochemistry of contemporary molecular targets involved in neurological and CNS disorders. Reviews presented in the series are mainly focused on clinical and therapeutic aspects of novel drugs intended for these targets. Frontiers in Clinical Drug Research - CNS and Neurological Disorders is a valuable resource for pharmaceutical scientists and postgraduate students seeking updated and critical information for developing clinical trials and devising research plans in the field of neurology. The second volume of this series features 8 chapters that cover a variety of topics including: -treatment of multiple sclerosis and schizophrenia -neurochemistry of tremors -relationship between GABA and Alzheimer’s disease therapy -relationship between neurological diseases and cancer -research on angiogenesis-related blindness

Quorum Sensing vs Quorum Quenching: A Battle with No End in Sight
Quorum Sensing vs Quorum Quenching: A Battle with No End in Sight

Author: Vipin Chandra Kalia

Publisher: Springer

Published: 2016-08-23

Total Pages: 0

ISBN-13: 9788132235484

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Microbial relationships with all life forms can be as free living, symbiotic or pathogenic. Human beings harbor 10 times more microbial cells than their own. Bacteria are found on the skin surface, in the gut and other body parts. Bacteria causing diseases are the most worrisome. Most of the infectious diseases are caused by bacterial pathogens with an ability to form biofilm. Bacteria within the biofilm are up to 1000 times more resistant to antibiotics. This has taken a more serious turn with the evolution of multiple drug resistant bacteria. Health Departments are making efforts to reduce high mortality and morbidity in man caused by them. Bacterial Quorum sensing (QS), a cell density dependent phenomenon is responsible for a wide range of expressions such as pathogenesis, biofilm formation, competence, sporulation, nitrogen fixation, etc. Majority of these organisms that are important for medical, agriculture, aquaculture, water treatment and remediation, archaeological departments are: Aeromonas, Acinetobacter, Bacillus, Clostridia, Enterococcus, Pseudomonas, Vibrio and Yersinia spp. Biosensors and models have been developed to detect QS systems. Strategies for inhibiting QS system through natural and synthetic compounds have been presented here. The biotechnological applications of QS inhibitors (QSIs) in diverse areas have also been dealt with. Although QSIs do not affect growth and are less likely to impose selective pressure on bacteria, however, a few reports have raised doubts on the fate of QSIs. This book addresses a few questions. Will bacteria develop mechanisms to evade QSIs? Are we watching yet another defeat at the hands of bacteria? Or will we be acting intelligently and survive the onslaughts of this Never Ending battle?