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Author: Robert J. Sawyer
Publisher: Macmillan
Published: 2005-11
Total Pages: 354
ISBN-13: 9780765313164
DOWNLOAD EBOOKA scientist in Berkeley, California discovers that a series of murders is the work of an insurance company. After collecting information on the genes of policy holders, the company analyzed them to see which ones were a bad risk and proceeded to kill them. By the author of The Terminal Experiment.
Author: John F. Atkins
Publisher: Springer Science & Business Media
Published: 2010-03-10
Total Pages: 473
ISBN-13: 0387893822
DOWNLOAD EBOOKThe literature on recoding is scattered, so this superb book ?lls a need by prov- ing up-to-date, comprehensive, authoritative reviews of the many kinds of recoding phenomena. Between 1961 and 1966 my colleagues and I deciphered the genetic code in Escherichia coli and showed that the genetic code is the same in E. coli, Xenopus laevis, and guinea pig tissues. These results showed that the code has been c- served during evolution and strongly suggested that the code appeared very early during biological evolution, that all forms of life on earth descended from a c- mon ancestor, and thus that all forms of life on this planet are related to one another. The problem of biological time was solved by encoding information in DNA and retrieving the information for each new generation, for it is easier to make a new organism than it is to repair an aging, malfunctioning one. Subsequently, small modi?cations of the standard genetic code were found in certain organisms and in mitochondria. Mitochondrial DNA only encodes about 10–13 proteins, so some modi?cations of the genetic code are tolerated that pr- ably would be lethal if applied to the thousands of kinds of proteins encoded by genomic DNA.
Author: Alison Heiser
Publisher:
Published: 2020-12-04
Total Pages:
ISBN-13: 9780578781112
DOWNLOAD EBOOKFrameShifting is a unique user-centered guide to collaborating with others that combines structure and creativity. The FrameShifting methodology draws upon Alison Heiser's extensive experience as an executive and consultant working with leaders and teams in blue chip organizations including P&G, LensCrafters, Michelin, Accenture, Microsoft, BASF, Steelcase and many others. FrameShifting breaks new ground with the concept of Frame Archetypes. We profile the FrameBuilder, FrameSeeker, FrameMaster and FreeRadical using stories, illustrations, and real-life examples to describe their skills, Achilles' heels, and opportunities for growth. All over the world teams are working together to solve challenges they've never seen before. And far too often, an endless series of meetings leave people frustrated and with little to show for their efforts. FrameShifting is a skill that can be learned, and with practice it will step change how leaders and teams collaborate to drive innovative problem-solving in any organization. From the Foreword: "What Alison and Mary have done is to illuminate the discipline of problem framing and using frameworks effectively, making what has historically been more of an art into a learnable science that consultants of all flavors can use to increase the impact of their work with clients. However, this book is not just for consultants. It's for any businessperson who wants to learn to solve gnarly problems - and, importantly, to solve the right problems - with greater insight and rigor. And, importantly, it's for collaborators who want to engage others in the exploration and solving of tough problems. FrameShifting is as much a collaboration approach as it is a problem-solving approach."-Melissa Quinn, Innovation Advisor and Coach, former COO and Managing Director, Doblin, Deloitte Consulting
Author: National Academies of Sciences, Engineering, and Medicine
Publisher: National Academies Press
Published: 2017-04-21
Total Pages: 149
ISBN-13: 0309453291
DOWNLOAD EBOOKAdvances in genetics and genomics are transforming medical practice, resulting in a dramatic growth of genetic testing in the health care system. The rapid development of new technologies, however, has also brought challenges, including the need for rigorous evaluation of the validity and utility of genetic tests, questions regarding the best ways to incorporate them into medical practice, and how to weigh their cost against potential short- and long-term benefits. As the availability of genetic tests increases so do concerns about the achievement of meaningful improvements in clinical outcomes, costs of testing, and the potential for accentuating medical care inequality. Given the rapid pace in the development of genetic tests and new testing technologies, An Evidence Framework for Genetic Testing seeks to advance the development of an adequate evidence base for genetic tests to improve patient care and treatment. Additionally, this report recommends a framework for decision-making regarding the use of genetic tests in clinical care.
Author:
Publisher: Elsevier
Published: 2018-01-29
Total Pages: 480
ISBN-13: 0444640770
DOWNLOAD EBOOKNeurogenetics, Part II, Volume 148, the latest release in the Handbook of Clinical Neurology, provides the latest information on the genetic methodologies that are having a significant impact on the study of neurological and psychiatric disorders. Using genetic science, researchers have identified over 200 genes that cause or contribute to neurological disorders. Still an evolving field of study, defining the relationship between genes and neurological and psychiatric disorders is expected to dramatically grow in scope. Part II builds on the foundation of Part I, expanding the coverage to dementias, paroxysmal disorders, neuromuscular disorders, white matter and demyelination diseases, cerebrovascular diseases, adult psychiatric disorders and cancer and phacomatoses. - Contains comprehensive coverage of neurogenetics - Details the latest science and its impact on our understanding of neurological, psychiatric disorders - Presents a focused reference for clinical practitioners and the neuroscience/neurogenetics research community
Author: John W. Pelley, PhD
Publisher: Elsevier Health Sciences
Published: 2011-11-30
Total Pages: 254
ISBN-13: 0323074464
DOWNLOAD EBOOKEffectively merge basic science and clinical skills with Elsevier's Integrated Review Biochemistry, by John W. Pelley, PhD. This concise, high-yield title in the popular Integrated Review Series focuses on the core knowledge in biochemistry while linking that information to related concepts from other basic science disciplines. Case-based questions at the end of each chapter enable you to gauge your mastery of the material, and a color-coded format allows you to quickly find the specific guidance you need. Online access via www.studentconsult.com - included with your purchase - allows you to conveniently access the book's complete text and illustrations online as well as relevant content from other Student Consult titles. This concise and user-friendly reference provides crucial guidance for the early years of medical training and USMLE preparation. Spend more time reviewing and less time searching thanks to an extremely focused, "high-yield" presentation. Gauge your mastery of the material and build confidence with both case-based, andUSMLE-style questions that provide effective chapter review and quick practice for your exams. Access the full contents online at www.studentconsult.com where you'll find the complete text and illustrations, "Integration Links" to bonus content in other Student Consult titles, an interactive community center with a wealth of additional resources, and much more! Grasp and retain vital concepts more easily thanks to a color-coded format, succinct,text, key concept boxes, and dynamic illustrations that facilitate learning in a highly visual approach. Effectively review for problem-based courses with the help of text boxes that help you clearly see the clinical relevance of the material. Great for visual learners!
Author: Robert E. Glass
Publisher: Univ of California Press
Published: 1982-01-01
Total Pages: 508
ISBN-13: 9780520046191
DOWNLOAD EBOOKAuthor: Antonio V. Delgado-Escueta
Publisher: Lippincott Williams & Wilkins
Published: 2005
Total Pages: 368
ISBN-13: 9780781752480
DOWNLOAD EBOOKThis volume is the first comprehensive text and clinical reference on idiopathic myoclonic epilepsies of infancy, childhood, adolescence, and adulthood. The world’s foremost experts describe the phenotypes and subtypes of myoclonic epilepsies and the underlying molecular defects and summarize cutting-edge advances in molecular genetics that shed new light on the etiologies of these syndromes. The book offers clinicians much-needed assistance in recognizing and diagnosing idiopathic myoclonic epilepsies and selecting appropriate treatment. Each chapter includes diagnostic and treatment algorithms to guide practitioners in clinical decision making.
Author: J. Larry Jameson
Publisher: Elsevier Health Sciences
Published: 2015-02-25
Total Pages: 3707
ISBN-13: 032332195X
DOWNLOAD EBOOKConsidered the definitive source in its field for over 35 years, Endocrinology: Adult and Pediatric, has been thoroughly updated to reflect today's recent advances in adult and pediatric endocrinology. Unique perspectives from a team of trusted, world-renowned experts ensure this medical reference book remains the most highly-regarded text in the field. Make the best clinical decisions with an enhanced emphasis on evidence-based practice and expert opinions on treatment strategies. Zero in on the most relevant and useful references with the aid of a more focused, concise bibliography. Locate information quickly, while still getting the complete coverage you expect. Now in full color, with special design treatment for at-a-glance pediatric content, helping to distinguish the pediatric content. Expanded coverage for key topics such as pediatric endocrinology and obesity mechanisms and treatment, in addition to today's hot topics in endocrinology, including endocrine disruptors, bariatric surgery, androgen deficiency, genetic causes of obesity, endocrine rhythms, and the use of tyrosine kinase inhibitors in thyroid cancer. New content addressing the latest advances in testosterone and estrogen replacement, as well as the new causes of calcium and phosphate disorders, new molecular causes of endocrine cancers, new genetic causes of reproductive disorders, and more. Updated clinical guidelines for diabetes, lipid disorders, obesity management, osteoporosis, and more, as well as essential treatment updates for the medical management of acromegaly, Cushing's Disease, hypercalcemia, and diabetes mellitus. New Key Points provide snapshots of what to expect in each chapter, or serve as a refresher of what you just read. Expert Consult eBook version included with purchase. This enhanced eBook experience allows you to search all of the text, figures, references, and videos from the book on a variety of devices.
Author: Robert G. Webster
Publisher: John Wiley & Sons
Published: 2014-01-06
Total Pages: 684
ISBN-13: 111863683X
DOWNLOAD EBOOKThe Textbook of Influenza is a comprehensive resource covering all aspects of influenza, from the genetic and molecular biology of the virus through to clinical aspects of the disease and the latest drug developments and treatments. This new edition has been completely revised and reflects the integration of disciplines concerning the emergence, evolution, pathogenesis and control of influenza viruses in the field of human and veterinary public health. Textbook of Influenza examines the lessons learnt from the latest pandemic and provides the current state of knowledge for many yet unresolved issues related to virus origin, spread, pathogenesis and disease severity to better prepare for future pandemics. It covers the background to recent advances in influenza genomics and reverse genetics which have allowed the identification of virus virulence factors and the analysis and reconstruction of influenza viruses such as the 1918 Spanish flu strain. This new edition is divided into eight key sections, containing chapters co-written by international experts from both the clinical and scientific communities, covering: • Influenza Perspectives • Structure and Replication • Evolution and Ecology • Epidemiology and Surveillance • Immunology • Vaccines and Vaccine Development • Clinical Aspects and Antivirals • Public Health Textbook of Influenza is for all those working in the area of influenza including clinical and basic scientists, immunologists, molecular and structural virologists, public health officials and global pandemic control planners.
