Fluorine Chemistry V4
Fluorine Chemistry V4

Author: J.H. Simons

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 815

ISBN-13: 0323142451

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Fluorine Chemistry, Volume IV provides an extensive survey and discussion on the physiological properties of fluoride ion and substances capable of producing it in aqueous solution. This book elaborates the detrimental effects of excessive fluoride ingestion, through the beneficial effects of optimal amounts, to recognized detrimental effects, such as dental caries accompanied by suboptimal fluoride intake. Fluoride metabolism is discussed in detail, including the capacity for storage of fluoride by the bones and rates of excretion of fluoride from the body. This text also covers the relation of fluoride ion to the health of teeth and bones. This publication is a good source for chemists and clinicians intending to acquire knowledge of the biological effects of fluoride.

Fluorine in Organic Chemistry
Fluorine in Organic Chemistry

Author: Richard D. Chambers

Publisher: CRC Press

Published: 2004

Total Pages: 426

ISBN-13: 9780849317903

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The introduction of carbon-fluorine bonds into organic compounds can profoundly influence their chemical and physical properties when compared to their non-fluorine-containing analogues, leading to a range of man-made materials with highly desirable properties. These molecules are of interest across the wide spectrum of industrial and academic organic chemistry, from pharmaceuticals, through fine and specialty chemicals to polymers. From Prozac to Teflon, many of the most important products of the chemical and life-science industries rely on organic fluorine chemistry for their useful properties. This book covers both the preparative methodologies and chemical properties of partially and highly fluorinated organic systems.

Guide to Fluorine NMR for Organic Chemists
Guide to Fluorine NMR for Organic Chemists

Author: William R. Dolbier, Jr.

Publisher: John Wiley & Sons

Published: 2016-08-24

Total Pages: 418

ISBN-13: 1118831098

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Following its well-received predecessor, this book offers an essential guide to chemists for understanding fluorine in spectroscopy. With over 1000 compounds and 100 spectra, the second edition adds new data – featuring fluorine effects on nitrogen NMR, chemical shifts, and coupling constants. • Explains how to successfully incorporate fluorine into target molecules and utilize fluorine substituents to structurally characterize organic compounds • Includes new data on nitrogen NMR, focusing on N-15, to portray the influence of fluorine upon nitrogen NMR chemical shifts and coupling constants • Expands on each chapter from the first edition with additional data and updated discussion from recent findings • "The flawless ordering of material covered in this stand-alone volume is such that information can be found very easily." – Angewandte Chemie review of the first edition, 2010

Modern Heterocyclic Chemistry, 4 Volumes
Modern Heterocyclic Chemistry, 4 Volumes

Author: Julio Alvarez-Builla

Publisher: John Wiley & Sons

Published: 2011-08-15

Total Pages: 2531

ISBN-13: 3527332014

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Eine Fülle von Information zum attraktiven Preis bietet Ihnen dieses vierbändige Handbuch der Heterocyclenchemie.

Fluorine and the Environment: Agrochemicals, Archaeology, Green Chemistry and Water
Fluorine and the Environment: Agrochemicals, Archaeology, Green Chemistry and Water

Author:

Publisher: Elsevier

Published: 2006-10-04

Total Pages: 297

ISBN-13: 0080465617

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Advances in Fluorine Science is a new book series presenting critical multidisciplinary overviews on areas in which fluorine and fluoride compounds have a decisive impact. The individual volumes of Advances in Fluorine Science are thematic, addressing comprehensively both the science and applications on topics including the Environment, Green chemistry, Medicine, Health & Life Sciences, New Technologies & Materials Science, Energy and the Earth Sciences. In the present volume, the key-position of fluoro-products in agriculture is reviewed, since a large percentage of agro-chemicals and pesticides contain at least one fluorine atom. However, improvements in the use of fluorine-based products in agrochemicals cannot be developed without taking into consideration a safer environment, on both levels of greener synthesis routes and a reduction of the negative impact on plants and organisms. Within this scope, fluorine has a very peculiar place, since its high reactivity yields several advantages, for instance in by-passing various polluting multi-step reactions. Fluorine-based materials are reviewed as efficient tools for protecting our cultural heritage. Also using up-to-date techniques such as ion beam analysis, this element can help relative dating applications, ranging from burial durations of archaeological bones and teeth to the determination of exposure ages of meteorites on the Antarctic ice shield. - Providing an original approach of the complex relationships between chemistry and the environment - Reviewing the key-position of fluoro-products in agriculture - Multidisciplinary contributions from chemists, geologists, biologists, environmentalists and industry staffs

Analytical Chemistry–4
Analytical Chemistry–4

Author: Mitsugi Senda

Publisher: Butterworth-Heinemann

Published: 2016-04-19

Total Pages: 177

ISBN-13: 1483153851

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Analytical Chemistry – 4 is a collection of plenary lectures presented at the International Congress on Analytical Chemistry, held in Kyoto, Japan on April 3-7, 1972. This book contains 11 chapters and begins with a summary of the kinetics of complex formation of metals with organic ligands in analytical chemistry. The subsequent chapters deal with the chelate compounds; the concepts of trace analysis; the developments in quantitative organic ultramicro elementary analysis; and the status of radiochemistry and its application to activation analysis. These topics are followed by presentation of precipitation-based ion-selective electrodes, with a particular emphasis on their most important analytical and physicochemical applications. A chapter briefly highlights the progress of analytical chemistry in Japan. The remaining chapters explore the direct metal and alloy analysis based on the selective modulation and resonance detection of conventional atomic absorption spectroscopy. These chapters also look into the status of analytical chemistry studies of air and water pollution. This text will be of great benefit to analytical chemists and researchers.

Progress in Inorganic Chemistry, Volume 26
Progress in Inorganic Chemistry, Volume 26

Author: Stephen J. Lippard

Publisher: John Wiley & Sons

Published: 2009-09-17

Total Pages: 502

ISBN-13: 0470166770

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This comprehensive series of volumes on inorganic chemistry provides inorganic chemists with a forum for critical, authoritative evaluations of advances in every area of the discipline. Every volume reports recent progress with a significant, up-to-date selection of papers by internationally recognized researchers, complemented by detailed discussions and complete documentation. Each volume features a complete subject index and the series includes a cumulative index as well.

Fluorine in Heterocyclic Chemistry Volume 1
Fluorine in Heterocyclic Chemistry Volume 1

Author: Valentine Nenajdenko

Publisher: Springer

Published: 2014-06-30

Total Pages: 683

ISBN-13: 3319043463

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This two-volume work combines comprehensive information on the chemistry of the fluorinated heterocycles. The material has been divided such that the first volume is dedicated to 5-membered fluorinated heterocycles and macrocycles, while the second volume combines data connected with the chemistry of fluorine containing 6-membered heterocycles. Both volumes will be of interest to synthetic organic chemists in general, and particularly for those colleagues working in the fields of heterocyclic-compound chemistry, materials chemistry, medicinal chemistry, and fluorine chemistry. All information is presented and classified clearly to be effective source for broad auditory of chemists. It will be interesting for scientists working in the field of inorganic and coordination chemistry. Fluorinated heterocycles are becoming increasingly important in many areas including the pharmaceutical industry, materials science and agriculture. The presence of fluorine can result in substantial functional changes in the biological as well as physicochemical properties of organic compounds. Incorporation of fluorine into drug molecules can greatly affect their physicochemical properties, such as bond strength, lipophilicity, bioavailability, conformation, electrostatic potential, dipole moment, pKa etc. as well as pharmacokinetic properties, such as tissue distribution, rate of metabolism and pharmacological properties, such as pharmacodynamics and toxicology.

Fluorine in Medicinal Chemistry and Chemical Biology
Fluorine in Medicinal Chemistry and Chemical Biology

Author: Iwao Ojima

Publisher: John Wiley & Sons

Published: 2009-03-23

Total Pages: 640

ISBN-13: 9780470744086

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The extraordinary potential of fluorine-containing molecules in medicinal chemistry and chemical biology has been recognized by researchers outside of the traditional fluorine chemistry field, and thus a new wave of fluorine chemistry is rapidly expanding its biomedical frontiers. With several of the best selling drugs in the world crucially containing fluorine atoms, the incorporation of fluorine to drug leads has become an essential practice in biomedical research, especially for drug design and discovery as well as development. Focusing on the unique and significant roles that fluorine plays in medicinal chemistry and chemical biology, this book reviews recent advances and future prospects in this rapidly developing field. Topics covered include: Discovery and development of fluorine containing drugs and drug candidates. New and efficient synthetic methods for medicinal chemistry and the optimisation of fluorine-containing drug candidates. Structural and chemical biology of fluorinated amino acids and peptides. Fluorine labels as probes in metabolic study, protein engineering and clinical diagnosis. Applications of 19F NMR spectroscopy in biomedical research. An appendix presents an invaluable index of all fluorine-containing drugs that have been approved by the US Food and Drug Administration, including information on structure and pharmaceutical action. Fluorine in Medicinal Chemistry and Chemical Biology will serve as an excellent reference source for graduate students as well as academic and industrial researchers who want to take advantage of fluorine in biomedical research.

Chemistry in Anhydrous, Prototropic Solvents
Chemistry in Anhydrous, Prototropic Solvents

Author: Barbara Grüttner

Publisher: Elsevier

Published: 2013-10-22

Total Pages: 341

ISBN-13: 1483161005

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Chemistry in Nonaqueous Ionizing Solvents: Volume II — Part 1 investigates the chemical and physico-chemical properties of substances dissolved or suspended in non-aqueous ionizing solvents (also known as water-like solvents). This volume is concerned with chemistry in anhydrous hydrogen cyanide and with inorganic chemistry in liquid hydrogen fluoride. This book is comprised of 35 chapters that cover topics ranging from commercial preparation of hydrogen fluoride to laboratory preparation of pure hydrogen fluoride as well as deuterium and tritium fluorides. Experimental techniques and the apparatus used in investigations of liquid hydrogen fluoride are also described. Subsequent chapters explore health risks and first aid with respect to handling hydrogen fluoride; physical properties of the pure solvent; inorganic solvates; solubilities and reactions of inorganic compounds; and acids and bases and their reactions with each other. The last two chapters are devoted to fluorides of the lanthanides and actinides in hydrogen fluoride. This monograph will be of interest to chemists.