A Textbook of Modern Toxicology

A Textbook of Modern Toxicology

Author: Ernest Hodgson

Publisher: McGraw-Hill Medical Publishing

Published: 1997

Total Pages: 518

ISBN-13:

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This revised edition reflects changes in the core curriculum subjects covered in the basic toxicology course for graduate students. Designed as an introductory textbook, it emphasizes the fundamental basis of toxic action at the cellular and molecular levels and lays the foundation for specialized courses in toxicology. Additional topics include metabolic activation and cellular protection, clinical toxicology diagnosis and treatment, ecosystems, environmental toxicology, ecotoxicology, case histories, and future consideration for environmental and human health.


Moving Questions

Moving Questions

Author: Joseph D Robinson

Publisher: Springer

Published: 2013-05-27

Total Pages: 383

ISBN-13: 1461476003

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This book describes a half century of research on cellular membrane transport and on metabolic energy capture and utilization. During this time-which begins in the late 1930s-the effort and imagination of various scientists overthrew reigning formulations, created novel explanatory models, and unified previously distinct experimental fields. My primary goal is to display the course of that research, showing how new experiments defined novel entities and processes, and how an encompassing field, bioenergetics, then emerged. A secondary goal is to present examples of mainstream biological research that illustrate how experimental results-seen as refutations, confirmations, and elabora tions-can sway opinion toward a solid consensus. This interpretation differs from the currently fashionable view of some commentators that stresses instead the central roles of power, prestige, gender, class, and ethnicity. In any case, the scien tific practices exhibited here deserve proper philosophical scrutiny. Although con straints of space have squeezed any analysis from this draft, brief mention of salient issues does appear in relevant chapters and in the final conclusions. (Oddly, histori ans and philosophers seem reluctant to deal with this science. Those who do consider biological topics tend to focus on the theory of evolution, even though the bulk of biological research in this century, in terms of papers published and technology influenced, has dealt not with evolution per se but with what may be termed physiology and biochemistry. And these endeavors, which are the aims, efforts, and accomplishments of the vast majority of biologists, have been largely ignored.


Ultradian Rhythms from Molecules to Mind

Ultradian Rhythms from Molecules to Mind

Author: David Lloyd

Publisher: Springer Science & Business Media

Published: 2008-08-27

Total Pages: 445

ISBN-13: 1402083521

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5. 1. 1 Biological Rhythms and Clocks From an evolutionary perspective, the adaptation of an organism’s behavior to its environment has depended on one of life’s fundamental traits: biological rhythm generation. In virtually all light-sensitive organisms from cyanobacteria to humans, biological clocks adapt cyclic physiology to geophysical time with time-keeping properties in the circadian (24 h), ultradian (24 h) domains (Edmunds, 1988; Lloyd, 1998; Lloyd et al. , 2001; Lloyd and Murray, 2006; Lloyd, 2007; Pittendrigh, 1993; Sweeney and Hastings, 1960) By definition, all rhythms exhibit regular periodicities since they constitute a mechanism of timing. Timing exerted by oscillatory mechanisms are found throughout the biological world and their periods span a wide range from milliseconds, as in the action potential of n- rons and the myocytes, to the slow evolutionary changes that require thousands of generations. In this context, to understand the synchronization of a population of coupled oscillators is an important problem for the dynamics of physiology in living systems (Aon et al. , 2007a, b; Kuramoto, 1984; Strogatz, 2003; Winfree, 1967). Circadian rhythms, the most intensively studied, are devoted to measuring daily 24 h cycles. A variety of physiological processes in a wide range of eukaryotic organisms display circadian rhythmicity which is characterized by the following major properties (Anderson et al. , 1985; Edmunds, 1988): (i) stable, autonomous (self-sustaining) oscillations having a free-running period under constant envir- mental conditions of ca.


Photosynthetic Nitrogen Assimilation and Associated Carbon and Respiratory Metabolism

Photosynthetic Nitrogen Assimilation and Associated Carbon and Respiratory Metabolism

Author: C.H. Foyer

Publisher: Springer Science & Business Media

Published: 2006-04-11

Total Pages: 300

ISBN-13: 0306481383

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According to many textbooks, carbohydrates are the photosynthesis and mitochondrial respiration fluctuate in a circadian manner in almost every unique final products of plant photosynthesis. However, the photoautotrophic production of organic organism studied. In addition, external triggers and environmental influences necessitate precise and nitrogenous compounds may be just as old, in appropriate re-adjustment of relative flux rates, to evolutionary terms, as carbohydrate synthesis. In the algae and plants of today, the light-driven assimilation prevent excessive swings in energy/resource provision of nitrogen remains a key function, operating and use. This requires integrated control of the alongside and intermeshing with photosynthesis and expression and activity of numerous key enzymes in respiration. Photosynthetic production of reduced photosynthetic and respiratory pathways, in order to carbon and its reoxidation in respiration are necessary co-ordinate carbon partioning and nitrogen assim- ation. to produce both the energy and the carbon skeletons required for the incorporation of inorganic nitrogen This volume has two principal aims. The first is to into amino acids. Conversely, nitrogen assimilation provide a comprehensive account of the very latest developments in our understanding of how green is required to sustain the output of organic carbon cells reductively incorporate nitrate and ammonium and nitrogen. Together, the sugars and amino acids into the organic compounds required for growth.


Atlas of Metabolic Diseases Second edition

Atlas of Metabolic Diseases Second edition

Author: William Nyhan

Publisher: CRC Press

Published: 2005-08-26

Total Pages: 801

ISBN-13: 144411459X

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In a field where even experts may find that years have elapsed since they last encountered a child with a given disorder, it is essential for the clinician to have a comprehensive source of practical and highly illustrated information covering the whole spectrum of metabolic disease to refer to. The second edition of this highly regarded book, auth


Fundamentals of Ecotoxicology

Fundamentals of Ecotoxicology

Author: Michael C. Newman

Publisher: CRC Press

Published: 2019-11-27

Total Pages: 682

ISBN-13: 1351133985

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This new edition is revised throughout and includes new and expanded information on natural resource damage assessment, the latest emerging contaminants and issues, and adds new international coverage, including case studies and rules and regulations. The text details key environmental contaminants, explores their fates in the biosphere, and discusses bioaccumulation and the effects of contaminants at increasing levels of ecological organization. Vignettes written by experts illustrate key themes or highlight especially pertinent examples. This edition offers an instructors' solution manual, PowerPoint slides, and supplemental images. Features: Adds all new discussions of natural resource damage assessment concepts and approaches Includes new vignettes written by leading guest authors Draws on materials from 2,500 cited sources, including 400+ new to this edition Adds numerous new entries to a useful glossary of 800+ terms Includes a new appendix discussing Brazilian environmental laws and regulations added to existing appendices outlining U.S., E.U., Chinese, Australian, and Indian environmental laws Fundamentals of Ecotoxicology: The Science of Pollution, Fifth Edition contains a broad overview of ecotoxicology and provides a basic understanding of the field. Designed as a textbook for use in introductory graduate or upper-level undergraduate courses in ecotoxicology, applied ecology, environmental pollution, and environmental science, it can also be used as a general reference for practicing environmental toxicologists.


Photosynthesis in Algae

Photosynthesis in Algae

Author: Anthony W. D. Larkum

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 499

ISBN-13: 9400710380

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This book introduces the reader to algal diversity as currently understood and then traces the photosynthetic structures and mechanisms that contribute so much to making the algae unique. Indeed the field is now so large that no one expert can hope to cover it all. The 19 articles are each written by experts in their area; ranging over all the essential aspects and making for a comprehensive coverage of the whole field. Important developments in molecular biology, especially transformation mutants in Chlamydomonas, are dealt with, as well as areas important to global climate change, carbon dioxide exchange, light harvesting, energy transduction, biotechnology and many others. The book is intended for use by graduate students and beginning researchers in the areas of molecular and cell biology, integrative biology, plant biology, biochemistry and biophysics, biotechnology, global ecology, and phycology.