Fibrinolytics and Antifibrinolytics
Author: F. Bachmann
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 614
ISBN-13: 3642566375
DOWNLOAD EBOOKWith contributions by numerous experts
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Author: F. Bachmann
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 614
ISBN-13: 3642566375
DOWNLOAD EBOOKWith contributions by numerous experts
Author: Eelco F. M. Wijdicks
Publisher: Oxford University Press
Published: 2018
Total Pages: 353
ISBN-13: 0190684747
DOWNLOAD EBOOKNeurocritical Care Pharmacotherapy: A Clinican's Guide is a practical, succinct but comprehensive pharmacy handbook provides up-to-date clinical guidance on the effective selection, prescription, and usage of neurocritical care drugs for patients with acute neurologic illnesses. The treatment of the critically ill neurologic patient is often difficult, specialized, and includes drugs infrequently used in other intensive care units such as antiepileptic drugs, osmotic agents or acute immunotherapy such as intravenous immunoglobulin and plasma exchange. This text discusses choosing the right combination of drugs; how to correctly prescribe and administer the drugs; how to monitor drug efficacy and side effects; how neurocritical care drugs interact with other medications; and comprehensive coverage of current treatment options. Key Feature of this Manual Include - A brief discussion of the basic pharmacology of each neurocritical drug, with an emphasis on how to select and use these drugs in multiple clinical contexts. - 150 drugs accompanied by a diagram for quick comprehension and drug administration guides. - Unique blending of expertise of neurointensivist with a critical care pharmacist to provide a vital resource for both specialities - References for further reading that are oriented toward utility in clinical practice.
Author: Kenneth J. Drobatz
Publisher: John Wiley & Sons
Published: 2018-10-11
Total Pages: 1520
ISBN-13: 1119028957
DOWNLOAD EBOOKTextbook of Small Animal Emergency Medicine offers an in-depth understanding of emergency disease processes and the underlying rationale for the diagnosis, treatment, monitoring, and prognosis for these conditions in small animals. A comprehensive reference on a major topic in veterinary medicine The only book in this discipline to cover the pathophysiology of disease in depth Edited by four respected experts in veterinary emergency medicine A core text for those studying for specialty examinations Includes access to a website with video clips, additional figures, and the figures from the book in PowerPoint Textbook of Small Animal Emergency Medicine offers an in-depth understanding of emergency disease processes and the underlying rationale for the diagnosis, treatment, monitoring, and prognosis for these conditions in small animals.
Author: Fritz Markwardt
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 663
ISBN-13: 3642668631
DOWNLOAD EBOOKDisturbances of haemostasis and thromboembolic disorders still constitute a great problem in clinical practice. Increasing insight into the mechanism of blood coagula tion has led to more effective therapy and prophylaxis. Particularly, the understand ing of the biochemistry of fibrinolysis has provided possibilities for the pharma cological interference of these processes, which has resulted in effective haemostatic agents and useful antithrombotic ones. The development of antifibrinolytics for interfering with pathological fibrinolytic processes is nearly complete and has led to the development of drugs essential to the therapy of hyperfibrinolytic bleeding. The search for fibrinolytics for dissolving intravascular thrombi has led to highly effective compounds. This development is still under way and promising results are hoped. Spontaneous dissolution of blood clots is a phenomenon which was described a century ago. First investigations of this process assured that there is in the organism a system capable of removing the fibrin which is formed during blood coagulation after it has fulfilled its physiological function. This fibrinolytic system is specifically adapted to the degradation of insoluble fibrin into soluble degradation products. In the past 30 years, thorough investigation of this system has clarified the fibrinolytic process, its physiological role and its meaning as a pathogenetic principle. A good knowledge of these processes is required for an understanding of the effects and side effects of fibrinolytics and antifibrinolytics, which comprise the basis of methods for the detection of fibrinolytic processes in the organism and of the control of therapy with these drugs.
Author: Fedor Bachmann
Publisher: Springer Science & Business Media
Published: 2001-01-25
Total Pages: 638
ISBN-13: 9783540661269
DOWNLOAD EBOOKThis book covers basic aspects of the molecular biology, biochemistry and pharmacology of the plasminogen-plasmin (fibrinolytic) system. Individual chapters, written by well-known experts in the field, are devoted to plasminogen and its activation, the tissue-type plasminogen activator (tPA), the urinary-type-plasminogen activator (uPA), inhibitors of the fibrinolytic system, and the assembly of fibrinolytic constituents on cell surfaces. The major part of the book deals with the therapeutic use of thrombolytic agents in myocardial infarction, deep venous thrombosis, pulmonary embolism, peripheral arterial occlusions and stroke. The newest thrombolytic agents are discussed in depth. Results of major clinical trials up to the end of 1999 are critically evaluated. The volume is a modern up-to-date presentation of the entire field of the treatment of arterial and venous thromboses with thrombolytic agents.
Author: Corey S. Scher
Publisher: Springer Nature
Published: 2021-03-12
Total Pages: 469
ISBN-13: 3030592952
DOWNLOAD EBOOKThis comprehensive book is written to inform and improve outcomes of patients in need of blood management during surgical procedures. Information is presented in an accessible format, allowing for immediate use in clinical practice. Beginning with an overview of the history of blood transfusions, early chapters present the foundational information needed to comprehend information in later chapters. Nuanced procedures, drugs, and techniques are covered, including new biologicals to assist clotting and blood substitutes. Further discussions focus on potential complications seen in blood transfusions, such as diseases of the coagulation system, pathogen transmissions, and acute lung injuries. Chapters also examine the complexities of treating specific demographics, of which include the geriatric patient and patients suffering from substance abuse. Essentials of Blood Product Management in Anesthesia Practice is an invaluable guide for anesthesiologists, surgeons, trauma physicians, and solid organ transplant providers.
Author: Hunter B. Moore
Publisher: Springer Nature
Published: 2020-10-12
Total Pages: 802
ISBN-13: 3030536068
DOWNLOAD EBOOKThe first edition of this publication was aimed at defining the current concepts of trauma induced coagulopathy by critically analyzing the most up-to-date studies from a clinical and basic science perspective. It served as a reference source for any clinician interested in reviewing the pathophysiology, diagnosis, and management of the coagulopathic trauma patient, and the data that supports it. By meticulously describing the methodology of most traditional as well as state of the art coagulation assays the reader is provided with a full understanding of the tests that are used to study trauma induced coagulopathy. With the growing interest in understanding and managing coagulation in trauma, this second edition has been expanded to 46 chapters from its original 35 to incorporate the massive global efforts in understanding, diagnosing, and treating trauma induced coagulopathy. The evolving use of blood products as well as recently introduced hemostatic medications is reviewed in detail. The text provides therapeutic strategies to treat specific coagulation abnormalities following severe injury, which goes beyond the first edition that largely was based on describing the mechanisms causing coagulation abnormalities. Trauma Induced Coagulopathy 2nd Edition is a valuable reference to clinicians that are faced with specific clinical challenges when managing coagulopathy.
Author: Keith Allman
Publisher:
Published: 2006
Total Pages: 1229
ISBN-13: 0198566093
DOWNLOAD EBOOKThe Oxford Handbook of Anaesthesia has been completely updated for the second edition. All chapters have been rewritten and a number of new expert authors have been brought on board. Additional new material includes anaesthesia for the critically ill, and a comprehensive section on anaesthetic risk including anaesthetic risk tables. The first section deals with preoperative issues affecting the administration of anaesthesia. Practical advice is provided covering the impact of medical disease on anaesthesia. The second section describes practical anaesthetic techniques for surgical specialties, including most subspecialties such as thoracic and neuroanaesthesia. Separate, comprehensive sections on paediatric and obstetric anaesthesia are included. The management of emergencies arising during anaesthesia are fully covered with helpful action plans and algorithms throughout. Uncommon conditions and their management are included, and there is an extensive drug formulary and guide to infusion drugs. As with the first edition, this new edition will be the essential handbook for anaesthetists, both junior and experienced, for registrars and those sitting exams, as well as ODPs and nurses involved in theatre area work and pre-assessment. It is the one book for anyone working in anaesthesia to keep to hand at all times!
Author: Davy C.H. Cheng
Publisher: Springer Nature
Published: 2020-11-06
Total Pages: 769
ISBN-13: 3030478874
DOWNLOAD EBOOKThis comprehensive yet concise book addresses current best practice in the combined areas of cardiac surgery and anesthesia, interventional minimally invasive cardiac procedures, perioperative management and monitoring, and critical care recovery. This book not only provides the latest best practices in the perioperative management of cardiac surgical patients, but also it summarizes the current clinical guidelines and algorithms from leading cardiac programs and professional societies. Contemporary best practice approaches are written by experts from leading cardiac surgical centers. The preoperative, intraoperative and postoperative management and recovery of surgical patients, including medication, monitoring techniques, and innovative surgical procedures, are presented by experts in the field of cardiac anesthesia and surgery. Perioperative clinical care guidelines, postoperative recovery pathways and models of care are presented with supporting protocols. Evidence-Based Practice in Perioperative Cardiac Anesthesia and Surgery is aimed at all cardiac anesthesiology consultants, fellows, and trainees; all cardiac surgery consultants, fellows, and trainees; nurses in perioperative care and those involved in patient recovery management; cardiac program administrative professionals; and all critical care consultants and trainees looking after cardiovascular surgical patients in the modern era.
Author: Craig S. Kitchens
Publisher: Elsevier Health Sciences
Published: 2013-02-20
Total Pages: 843
ISBN-13: 1455733296
DOWNLOAD EBOOKA unique clinical focus makes Consultative Hemostasis and Thrombosis, 3rd Edition your go-to guide for quick, practical answers on managing the full range of bleeding and clotting disorders. Emphasizing real-world problems and solutions, Dr. Craig S. Kitchens, Dr. Barbara A. Konkle, and Dr. Craig M. Kessler provide all the clinical guidance you need to make optimal decisions on behalf of your patients and promote the best possible outcomes. Consult this title on your favorite e-reader with intuitive search tools and adjustable font sizes. Elsevier eBooks provide instant portable access to your entire library, no matter what device you're using or where you're located. Efficiently look up concise descriptions of each condition, its associated symptoms, laboratory findings, diagnosis, differential diagnosis, and treatment. Get the latest information on hot topics such as Disseminated Intravascular Coagulation, Thrombophilia, Clinical and Laboratory Assessment and Management, Thrombotic -Thrombocytopenic Purpura, and Heparin-Induced Thrombocytopenia. Apply today’s newest therapies, including those that are quickly becoming standard in this fast-changing field. Meet the needs of specific patient groups with a new chapter on Bleeding and the Management of Hemorrhagic Disorders in Pregnancy and an extensively updated chapter on Thrombosis and Cancer. Zero in on key information with a new user-friendly design, and all-new full-color format, abundant laboratory protocols, and at-a-glance tables and charts throughout.