Preterm Birth

Preterm Birth

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2007-05-23

Total Pages: 791

ISBN-13: 030910159X

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The increasing prevalence of preterm birth in the United States is a complex public health problem that requires multifaceted solutions. Preterm birth is a cluster of problems with a set of overlapping factors of influence. Its causes may include individual-level behavioral and psychosocial factors, sociodemographic and neighborhood characteristics, environmental exposure, medical conditions, infertility treatments, and biological factors. Many of these factors co-occur, particularly in those who are socioeconomically disadvantaged or who are members of racial and ethnic minority groups. While advances in perinatal and neonatal care have improved survival for preterm infants, those infants who do survive have a greater risk than infants born at term for developmental disabilities, health problems, and poor growth. The birth of a preterm infant can also bring considerable emotional and economic costs to families and have implications for public-sector services, such as health insurance, educational, and other social support systems. Preterm Birth assesses the problem with respect to both its causes and outcomes. This book addresses the need for research involving clinical, basic, behavioral, and social science disciplines. By defining and addressing the health and economic consequences of premature birth, this book will be of particular interest to health care professionals, public health officials, policy makers, professional associations and clinical, basic, behavioral, and social science researchers.


Fetal and Neonatal Lung Development

Fetal and Neonatal Lung Development

Author: Alan H. Jobe

Publisher: Cambridge University Press

Published: 2016-04-18

Total Pages:

ISBN-13: 1316665178

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Lung disease affects more than 600 million people worldwide. While some of these lung diseases have an obvious developmental component, there is growing appreciation that processes and pathways critical for normal lung development are also important for postnatal tissue homeostasis and are dysregulated in lung disease. This book provides an authoritative review of fetal and neonatal lung development and is designed to provide a diverse group of scientists, spanning the basic to clinical research spectrum, with the latest developments on the cellular and molecular mechanisms of normal lung development and injury-repair processes, and how they are dysregulated in disease. The book covers genetics, omics, and systems biology as well as new imaging techniques that are transforming studies of lung development. The reader will learn where the field of lung development has been, where it is presently, and where it is going in order to improve outcomes for patients with common and rare lung diseases.


Fetal Growth Restriction

Fetal Growth Restriction

Author: Luciano Marcondes Machado Nardozza

Publisher: Springer

Published: 2018-12-14

Total Pages: 243

ISBN-13: 3030000516

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Fetal growth restriction (FGR) is a condition that affects 5%–10% of all pregnancies and is the second most common cause of perinatal mortality. Fetuses with FGR present with a greater risk of long-term health defects as impaired neurological and cognitive development and cardiovascular or endocrine diseases in adulthood. Due to its high prevalence and serious long term consequences, an in-depth understating of the diagnosis and management of FGR is essential for all those professionals involved in prenatal care, since it can prevent unwanted outcomes both to the mother and to the newborn. On the last years, the knowledge about fetal growth restriction has evolved considerably, with an increasing number of articles being published on this topic and new concepts being described, including new diagnostic guidelines. Even so, there are no recent books fully dedicated to FGR; this theme has only generally been discussed in chapters in larger obstetrics and neonatology books. This current book intends to present and discuss the state of the art on FGR in a clear and didactical way. It will focus on the main topics related to FGR, including its etiology, classification, prediction, diagnosis, and management, as well as on its neurological complications and maternal cardiovascular involvement. Written by experienced and renowned gynecologists from Brazil, Italy and the US, this book will be a comprehensive guide, directed to all gynecologists, radiologists and general practitioners who are involved in prenatal care, as well as to interns, residents, professors and researchers in the field.


Placental-Fetal Growth Restriction

Placental-Fetal Growth Restriction

Author: Christoph Lees

Publisher: Cambridge University Press

Published: 2018-03-31

Total Pages: 300

ISBN-13: 1108548180

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Master the effective evaluation, analysis and management of placental-fetal growth restriction (PFGR), reducing the risk of perinatal mortality and morbidity in patients worldwide. Extensively researched by international experts, this manual provides practitioners with a detailed, hands-on approach to the practical 'pearls' for direct patient management. This authoritative volume advises on matters such as the correct evaluation and management of high-risk patients in danger of PFGR through to delivery. Extensive and wide-ranging, this book is an invaluable companion to the developing research interest and clinical applications in PFGR, including developmental outcomes in early childhood. Featuring a critical evaluation of a variety of abnormal conditions, such as fetal hypoxia, which are clearly displayed through extensive illustrations. This essential toolkit ensures that practitioners of all levels can effectively limit the risk of mortality and morbidity, and reach the correct diagnosis, first-time.


Small for Gestational Age

Small for Gestational Age

Author: Wieland Kiess

Publisher: Karger Medical and Scientific Publishers

Published: 2009-01-01

Total Pages: 177

ISBN-13: 3805586574

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Intrauterine growth restriction in the human, the origin of many serious medical, ethical, socioeconomic and humanitarian issues, still needs in-depth studies.The current volume presents the latest research results and offers detailed discussions on clinical care. The term small for gestational age (SGA) is defined and manifestations of prenatal growth retardation and its etiology are described. Special emphasis is placed on the role of genetic defects, in particular in the IGF/GH axis. Besides, not only the immediate consequences for SGA neonates and their clinical care are examined, but also possible sequelae in childhood. A study of utmost importance considers the neurological and intellectual consequences for SGA children. It is further revealed that fetal growth restriction can adversely affect health well into adulthood, and increase the risk for type 2 diabetes. Finally, interesting insights into the causes and consequences of low birth weight in developing countries are provided.This publication is a must for pediatricians, neonatologists, obstetricians and endocrinologists, as well as anyone interested in embryology, genetics, diabetes, clinical nutrition, molecular biology and neuroendocrinology.


Reducing Birth Defects

Reducing Birth Defects

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2003-10-27

Total Pages: 270

ISBN-13: 0309166837

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Each year more than 4 million children are born with birth defects. This book highlights the unprecedented opportunity to improve the lives of children and families in developing countries by preventing some birth defects and reducing the consequences of others. A number of developing countries with more comprehensive health care systems are making significant progress in the prevention and care of birth defects. In many other developing countries, however, policymakers have limited knowledge of the negative impact of birth defects and are largely unaware of the affordable and effective interventions available to reduce the impact of certain conditions. Reducing Birth Defects: Meeting the Challenge in the Developing World includes descriptions of successful programs and presents a plan of action to address critical gaps in the understanding, prevention, and treatment of birth defects in developing countries. This study also recommends capacity building, priority research, and institutional and global efforts to reduce the incidence and impact of birth defects in developing countries.


The Health Effects of Cannabis and Cannabinoids

The Health Effects of Cannabis and Cannabinoids

Author: National Academies of Sciences, Engineering, and Medicine

Publisher: National Academies Press

Published: 2017-03-31

Total Pages: 487

ISBN-13: 0309453070

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Significant changes have taken place in the policy landscape surrounding cannabis legalization, production, and use. During the past 20 years, 25 states and the District of Columbia have legalized cannabis and/or cannabidiol (a component of cannabis) for medical conditions or retail sales at the state level and 4 states have legalized both the medical and recreational use of cannabis. These landmark changes in policy have impacted cannabis use patterns and perceived levels of risk. However, despite this changing landscape, evidence regarding the short- and long-term health effects of cannabis use remains elusive. While a myriad of studies have examined cannabis use in all its various forms, often these research conclusions are not appropriately synthesized, translated for, or communicated to policy makers, health care providers, state health officials, or other stakeholders who have been charged with influencing and enacting policies, procedures, and laws related to cannabis use. Unlike other controlled substances such as alcohol or tobacco, no accepted standards for safe use or appropriate dose are available to help guide individuals as they make choices regarding the issues of if, when, where, and how to use cannabis safely and, in regard to therapeutic uses, effectively. Shifting public sentiment, conflicting and impeded scientific research, and legislative battles have fueled the debate about what, if any, harms or benefits can be attributed to the use of cannabis or its derivatives, and this lack of aggregated knowledge has broad public health implications. The Health Effects of Cannabis and Cannabinoids provides a comprehensive review of scientific evidence related to the health effects and potential therapeutic benefits of cannabis. This report provides a research agendaâ€"outlining gaps in current knowledge and opportunities for providing additional insight into these issuesâ€"that summarizes and prioritizes pressing research needs.


Maternal-Fetal Nutrition During Pregnancy and Lactation

Maternal-Fetal Nutrition During Pregnancy and Lactation

Author: Michael E. Symonds

Publisher: Cambridge University Press

Published: 2010-01-28

Total Pages: 217

ISBN-13: 0521887097

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With the aim to improve clinicians' understanding of the important effects nutrition can have on maternal health and fetal and neonatal development, Maternal-Fetal Nutrition During Pregnancy and Lactation defines the nutritional requirements with regard to the stage of development and growth, placing scientific developments into clinical context.


Weight Gain During Pregnancy

Weight Gain During Pregnancy

Author: National Research Council

Publisher: National Academies Press

Published: 2010-01-14

Total Pages: 868

ISBN-13: 0309131138

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As women of childbearing age have become heavier, the trade-off between maternal and child health created by variation in gestational weight gain has become more difficult to reconcile. Weight Gain During Pregnancy responds to the need for a reexamination of the 1990 Institute of Medicine guidelines for weight gain during pregnancy. It builds on the conceptual framework that underscored the 1990 weight gain guidelines and addresses the need to update them through a comprehensive review of the literature and independent analyses of existing databases. The book explores relationships between weight gain during pregnancy and a variety of factors (e.g., the mother's weight and height before pregnancy) and places this in the context of the health of the infant and the mother, presenting specific, updated target ranges for weight gain during pregnancy and guidelines for proper measurement. New features of this book include a specific range of recommended gain for obese women. Weight Gain During Pregnancy is intended to assist practitioners who care for women of childbearing age, policy makers, educators, researchers, and the pregnant women themselves to understand the role of gestational weight gain and to provide them with the tools needed to promote optimal pregnancy outcomes.