Exploring the Frontiers of Innovation to Tackle Microbial Threats
Exploring the Frontiers of Innovation to Tackle Microbial Threats

Author: National Academies of Sciences, Engineering, and Medicine

Publisher: National Academies Press

Published: 2020-09-10

Total Pages: 179

ISBN-13: 0309675332

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On December 4â€"5, 2019, the National Academies of Sciences, Engineering, and Medicine held a 1.5-day public workshop titled Exploring the Frontiers of Innovation to Tackle Microbial Threats. The workshop participants examined major advances in scientific, technological, and social innovations against microbial threats. Such innovations include diagnostics, vaccines (both development and production), and antimicrobials, as well as nonpharmaceutical interventions and changes in surveillance. This publication summarizes the presentations and discussions from the workshop.

Exploring the Frontiers of Innovation to Tackle Microbial Threats
Exploring the Frontiers of Innovation to Tackle Microbial Threats

Author: Engineering National Academies of Sciences (and Medicine)

Publisher:

Published: 2020

Total Pages: 158

ISBN-13: 9780309675345

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On December 4-5, 2019, the National Academies of Sciences, Engineering, and Medicine held a 1.5-day public workshop titled Exploring the Frontiers of Innovation to Tackle Microbial Threats. The workshop participants examined major advances in scientific, technological, and social innovations against microbial threats. Such innovations include diagnostics, vaccines (both development and production), and antimicrobials, as well as nonpharmaceutical interventions and changes in surveillance. This publication summarizes the presentations and discussions from the workshop.

Combating Antimicrobial Resistance
Combating Antimicrobial Resistance

Author: National Academies of Sciences, Engineering, and Medicine

Publisher: National Academies Press

Published: 2018-01-08

Total Pages: 173

ISBN-13: 0309466520

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As of 2017, the emergence and spread of antimicrobial resistance continues unabated around the world, leaving devastating health and economic outcomes in its wake. Those consequences will multiply if collaborative global action is not taken to address the spread of resistance. Major drivers of antimicrobial resistance in humans have been accelerated by inappropriate antimicrobial prescribing in health care practices; the inappropriate use of antimicrobials in livestock; and the promulgation of antibiotic resistance genes in the environment. To explore the issue of antimicrobial resistance, the Forum of Microbial Threats planned a public workshop. Participants explored issues of antimicrobial resistance through the lens of One Health, which is a collaborative approach of multiple disciplines - working locally, nationally, and globally - for strengthening systems to counter infectious diseases and related issues that threaten human, animal, and environmental health, with an end point of improving global health and achieving gains in development. They also discussed immediate and short-term actions and research needs that will have the greatest effect on reducing antimicrobial resistance, while taking into account the complexities of bridging different sectors and disciplines to address this global threat. This publication summarizes the presentations and discussions from the workshop.

Understanding the Economics of Microbial Threats
Understanding the Economics of Microbial Threats

Author: National Academies of Sciences, Engineering, and Medicine

Publisher: National Academies Press

Published: 2018-11-21

Total Pages: 169

ISBN-13: 0309483050

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Microbial threats, including endemic and emerging infectious diseases and antimicrobial resistance, can cause not only substantial health consequences but also enormous disruption to economic activity worldwide. While scientific advances have undoubtedly strengthened our ability to respond to and mitigate the mortality of infectious disease threats, events over the past two decades have illustrated our continued vulnerability to economic consequences from these threats. To assess the current understanding of the interaction of infectious disease threats with economic activity and suggest potential new areas of research, the National Academies of Sciences, Engineering, and Medicine planned a 1.5-day public workshop on understanding the economics of microbial threats. This workshop built on prior work of the Forum on Microbial Threats and aimed to help transform current knowledge into immediate action. This publication summarizes the presentations and discussions from the workshop.

The Impact of Globalization on Infectious Disease Emergence and Control
The Impact of Globalization on Infectious Disease Emergence and Control

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2006-04-01

Total Pages: 247

ISBN-13: 0309100984

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Globalization is by no means a new phenomenon; transcontinental trade and the movement of people date back at least 2,000 years, to the era of the ancient Silk Road trade route. The global spread of infectious disease has followed a parallel course. Indeed, the emergence and spread of infectious disease are, in a sense, the epitome of globalization. Although some experts mark the fall of the Berlin Wall as the beginning of this new era of globalization, others argue that it is not so new. The future of globalization is still in the making. Despite the successful attempts of the developed world during the course of the last century to control many infectious diseases and even to eradicate some deadly afflictions, 13 million people worldwide still die from such diseases every year. On April 16 and 17, 2002, the Forum on Emerging Infections held a working group discussion on the influence of globalization on the emergence and control of infectious diseases. The contents of the unattributed sections are based on the presentations and discussions that took place during the workshop. The Impact of Globalization on Infectious Disease Emergence and Control report summarizes the presentations and discussions related to the increasing cross-border and cross-continental movements of people and how this could exacerbate the emergence and global spread of infectious diseases. This report also summarizes the means by which sovereign states and nations must adopt a global public health mind-set and develop a new organizational framework to maximize the opportunities and overcome the challenges created by globalization and build the necessary capacity to respond effectively to emerging infectious disease threats.

Combating Antimicrobial Resistance
Combating Antimicrobial Resistance

Author: National Academies of Sciences, Engineering, and Medicine

Publisher:

Published: 2017

Total Pages: 152

ISBN-13: 9780309466530

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"As of 2017, the emergence and spread of antimicrobial resistance continues unabated around the world, leaving devastating health and economic outcomes in its wake. Those consequences will multiply if collaborative global action is not taken to address the spread of resistance. Major drivers of antimicrobial resistance in humans have been accelerated by inappropriate antimicrobial prescribing in health care practices; the inappropriate use of antimicrobials in livestock; and the promulgation of antibiotic resistance genes in the environment. To explore the issue of antimicrobial resistance, the Forum of Microbial Threats planned a public workshop. Participants explored issues of antimicrobial resistance through the lens of One Health, which is a collaborative approach of multiple disciplines - working locally, nationally, and globally - for strengthening systems to counter infectious diseases and related issues that threaten human, animal, and environmental health, with an end point of improving global health and achieving gains in development. They also discussed immediate and short-term actions and research needs that will have the greatest effect on reducing antimicrobial resistance, while taking into account the complexities of bridging different sectors and disciplines to address this global threat. This publication summarizes the presentations and discussions from the workshop"--Publisher's description.

How to Fight Harmful Microbial Bugs and Superbugs?
How to Fight Harmful Microbial Bugs and Superbugs?

Author: Alain Fischer

Publisher: Frontiers Media SA

Published: 2021-09-01

Total Pages: 209

ISBN-13: 2889714667

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The evolution of human beings has been shaped to a large extent by microbes. A number of microbes are innocuous or even contribute to our health equilibrium. This is the case of bacteria and viral phages present in our gut. However, several bacteria, viruses, parasites, and fungi are damaging our bodies, causing a number of acute and chronic diseases. Until recently, these bugs represented the main causes of death. Better hygiene, vaccines, antibiotics and other anti-microbial drugs have resulted in a better control or cure of many infections. However, malaria, tuberculosis, and AIDS still represent major threats in several countries and the recent epidemics of Ebola and Zika demonstrate how vulnerable we are to newly emerging viruses. Furthermore, diarrhea and pneumonia caused by bacteria or viruses still kill millions of children worldwide. Most importantly, bacteria resistant to existing antibiotics are multiplying at a high pace and these superbugs are expected to kill more and more people in the coming years. Clearly, we need to develop more effective approaches to tackle bugs and superbugs. Better hygiene and better vaccine coverage must be considered first and education of kids is essential in this respect. This is the main objective of this series of papers published in Frontiers for Young Minds under the heading “How to Fight Harmful Microbial Bugs and Superbugs?”. Another key objective of the collection is to elicit the interest of children for research on innovative anti-microbial therapies and vaccines.

Applying Lessons Learned from Covid-19 Research and Development to Future Epidemics
Applying Lessons Learned from Covid-19 Research and Development to Future Epidemics

Author: National Academies of Sciences Engineering and Medicine

Publisher:

Published: 2024-05-23

Total Pages: 0

ISBN-13: 9780309707848

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The COVID-19 pandemic catalyzed unparalleled speed and cross-sector collaboration in the innovation of tools and technologies to address an emerging infectious disease outbreak. Continued innovation and collaboration in rapid development and implementation of new vaccines, therapeutics, and diagnostics is central to future outbreak preparedness. The National Academies Forum on Microbial Threats; Forum on Drug Discovery, Development, and Translation; and the Forum on Medical and Public Health Preparedness for Emergencies and Disasters held a workshop in December 2022 to explore how innovative approaches in research can enhance health systems preparedness and responses to emerging infectious diseases and dangerous pathogens. Workshop participants reflected on critical scientific infrastructure for stakeholder coordination and innovations that can facilitate rapid and effective preparedness and response to emerging infectious disease threats. This Proceedings of a Workshop summarizes the discussions held during the workshop.

Nature at War
Nature at War

Author: Thomas Robertson

Publisher: Cambridge University Press

Published: 2020-04-02

Total Pages: 399

ISBN-13: 1108419763

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"World War II was the largest and most destructive conflict in human history. It was an existential struggle that pitted irreconcilable political systems and ideologies against one another across the globe in a decade of violence unlike any other. There is little doubt today that the United States had to engage in the fighting, especially after the Japanese attack on Pearl Harbor on December 7, 1941. The conflict was, in the words of historians Allan Millett and Williamson Murray, "a war to be won." As the world's largest industrial power, the United States put forth a supreme effort to produce the weapons, munitions, and military formations essential to achieving victory. When the war finally ended, the finale signaled by atomic mushroom clouds over Hiroshima and Nagasaki, upwards of 60 million people had perished in the inferno. Of course, the human toll represented only part of the devastation; global environments also suffered greatly. The growth and devastation of the Second World War significantly changed American landscapes as well. The war created or significantly expanded a number of industries, put land to new uses, spurred urbanization, and left a legacy of pollution that would in time create a new term: Superfund site"--

Disease Control Priorities, Third Edition (Volume 6)
Disease Control Priorities, Third Edition (Volume 6)

Author: King K. Holmes

Publisher: World Bank Publications

Published: 2017-11-06

Total Pages: 1027

ISBN-13: 1464805253

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Infectious diseases are the leading cause of death globally, particularly among children and young adults. The spread of new pathogens and the threat of antimicrobial resistance pose particular challenges in combating these diseases. Major Infectious Diseases identifies feasible, cost-effective packages of interventions and strategies across delivery platforms to prevent and treat HIV/AIDS, other sexually transmitted infections, tuberculosis, malaria, adult febrile illness, viral hepatitis, and neglected tropical diseases. The volume emphasizes the need to effectively address emerging antimicrobial resistance, strengthen health systems, and increase access to care. The attainable goals are to reduce incidence, develop innovative approaches, and optimize existing tools in resource-constrained settings.