EXPERIMENTAL PHARMACOLOGY -- II
Author: Ghanshyam Panigrahi
Publisher:
Published: 2020-02
Total Pages: 110
ISBN-13: 9789388897556
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Gastrointestinal Pharmacology
Author: Beverley Greenwood-Van Meerveld
Publisher: Springer
Published: 2017-04-19
Total Pages: 446
ISBN-13: 3319563602
DOWNLOAD EBOOKThis volume aims to connect current ideas and concepts about GI disorders with the search for novel therapeutics. Towards this goal, authors provide a timely state-of-the-art overview of the GI tract in health and disease, current treatment approaches and ongoing developments in drug discovery, and their potential for the better treatment of patients with GI disorders.
Practical Manual of Experimental and Clinical Pharmacology
Author: Bikash Mehdi
Publisher: Jaypee Brothers,Medical Publishers Pvt. Limited
Published: 2016-10-26
Total Pages: 430
ISBN-13: 9789386150721
DOWNLOAD EBOOKDrugs on Trial
Author: Andreas-Holger Maehle
Publisher: Rodopi
Published: 1999
Total Pages: 388
ISBN-13: 9789042007833
DOWNLOAD EBOOKThis book describes the main issues of eighteenth-century pharmacology and therapeutics and provides detailed case studies of three key areas: lithontriptics (remedies against urinary stones), opium, and Peruvian bark (quinine).
Reactive Oxygen Species
Author: Harald H. H. W. Schmidt
Publisher: Springer Nature
Published: 2021-02-23
Total Pages: 425
ISBN-13: 3030685101
DOWNLOAD EBOOKReactive oxygen species (ROS) have been implicated in almost every human disease phenotype, without much, if any, therapeutic consequence foremost exemplified by the failure of the so-called anti-oxidants. This book is a game changer for the field and many clinical areas such as cardiology and neurology. The term ‘oxidative stress’ is abandoned and replaced with a systems medicine and network pharmacology-based mechanistic approach to disease. The ROS-related drugs discussed here target either ROS- forming or ROS -modifying enzymes for which there is strong clinical evidence. In addition, ROS targets are included as they jointly participate in causal mechanisms of disease. This approach is transforming the ROS field and represents a breakthrough in redox medicine indicating a path to patient benefit. In the coming years more targets and drugs may be discovered, but the approach will remain the same and this book will thus become, and for many years remain, the leading reference for ROSopathies and their treatment by network pharmacology. Chapter "Soluble Guanylate Cyclase Stimulators and Activators" is available open access under a Creative Commons Attribution 4.0 International License via link.springer.com.
Concepts in Biochemical Pharmacology
Author: Bernard B. Brodie
Publisher: Springer Science & Business Media
Published: 2013-11-27
Total Pages: 797
ISBN-13: 3642651771
DOWNLOAD EBOOKThis volume of the Handbook of Experimental Pharmacology (Concepts in Biochemical Pharmacology) will show that pharma cology has finally arrived as a true discipline in its own right, and is no longer the handmaiden of organic chemistry and physiology. Instead it is an amalgam of all the biological sciences including biochemistry, biophysical chemistry, physiology, pathology and clinical medicine. In the volumes that make up Concepts in Bio chemical Pharmacology we hope to convince Medical Schools what should now be obvious, that pharmacology is no longer that dull topic bridging the basic sciences with medicine, but is probably the most important subject in the medical curriculum. We are grateful for the advice of Dr. Byron Clark, Director of the Pharmacology-Toxicology Program at the National Institutes of Health whose support made possible much of the work described in this volume. Contents Section Four: Methods 01 Stooging the MetoholiBm 01 Drugs Subsection A. Assay 01 Drugs and Their M etoholites Chapter 22 : Basic Principles in Development of Methods for Drug Assay. B. B. BRODIE. With 2 Figures 1 1 A. Introduction . . . . . . . . . . B. Principles of Developing a Method. . . . . . 1 I. Section of Method of Assay . . . . . . 1 II. Choice of Solvent for Extraction of Drug 2 III. Adsorption of Drugs by Glass Surfaces . . . . . . . . . . . . . . 3 IV. Recoveries of Known Amounts of Compound from Biological Material. 4 V. Assessment of Sensitivity 5 VI. Assessment of Specificity 5 References. . . . . . . . . . .
Concepts and Principles of Pharmacology
Author: James E. Barrett
Publisher: Springer Nature
Published: 2019-12-24
Total Pages: 457
ISBN-13: 3030353621
DOWNLOAD EBOOKCelebrating 100 years of HEP, this volume will discuss key pharmacological discoveries and concepts of the past 100 years. These discoveries have dramatically changed the medical treatment paradigms of many diseases and these concepts have and will continue to shape discovery of new medicinies. Newly evolving technologies will similarly be discussed as they will shape the future of the pharmacology and, accordingly, medical therapy.
Organotypic Models in Drug Development
Author: Monika Schäfer-Korting
Publisher: Springer Nature
Published: 2021-03-25
Total Pages: 325
ISBN-13: 3030700631
DOWNLOAD EBOOKThis book provides latest findings in organotypic models in drug development and provides the scientific resonance needed in an emerging field of research in disciplines, such as molecular medicine, physiology, and pathophysiology. Today the research on human-based test systems has gained major interest and funding in the EU and the US has increased over the last years. Moreover, so-called 3R (reduce, replace, refine animal experiments) centres have been established worldwide.
Good Research Practice in Non-Clinical Pharmacology and Biomedicine
Author: Anton Bespalov
Publisher: Springer Nature
Published: 2020-01-01
Total Pages: 424
ISBN-13: 3030336565
DOWNLOAD EBOOKThis open access book, published under a CC BY 4.0 license in the Pubmed indexed book series Handbook of Experimental Pharmacology, provides up-to-date information on best practice to improve experimental design and quality of research in non-clinical pharmacology and biomedicine.
Practical Pharmacology for the Pharmaceutical Sciences
Author: D. Michael Salmon
Publisher: John Wiley & Sons
Published: 2013-12-19
Total Pages: 162
ISBN-13: 1118696565
DOWNLOAD EBOOKPractical Pharmacology for the Pharmaceutical Sciences is a lab survival guide for those studying Pharmacology, providing hands-on advice on developing pharmacology laboratory and data handling skills. Suitable for both undergraduates and postgraduates, it focuses on laboratory techniques rather than computer-simulated data. It also guides the reader through the process of communicating experimental results in a variety of formats, including posters, oral presentations and project reports. Split into three main areas, the following topics are covered in detail: Preparation for Experimental Pharmacology Legal aspects Fundamentals of Pharmacology Definitions, calculations and statistics Experiments in Pharmacology Microtitre-based techniques using isolated cells In vitro techniques using isolated tissues and organs Biochemical techniques using cell-free systems Communicating experimental results Data presentation How to write scientific reports Pharmacological literature Supported with numerous questions throughout the text, as well as step by step instructions for practical experiments, this book presents an approach to learning pharmacology through an appreciation of authentic experimental data.
