Emphasizing the changes worked by circulation and copying, interpretation and debate, this book uses the case to explore how pictures succeed and fail, gain acceptance and spark controversy. It reveals how embryonic development was made a process that we can see, compare, and discuss, and how copying - usually dismissed as unoriginal
Icons of Life tells the engrossing and provocative story of an early twentieth-century undertaking, the Carnegie Institution of Washington's project to collect thousands of embryos for scientific study. Lynn M. Morgan blends social analysis, sleuthing, and humor to trace the history of specimen collecting. In the process, she illuminates how a hundred-year-old scientific endeavor continues to be felt in today's fraught arena of maternal and fetal politics. Until the embryo collecting project-which she follows from the Johns Hopkins anatomy department, through Baltimore foundling homes, and all the way to China-most people had no idea what human embryos looked like. But by the 1950s, modern citizens saw in embryos an image of "ourselves unborn," and embryology had developed a biologically based story about how we came to be. Morgan explains how dead specimens paradoxically became icons of life, how embryos were generated as social artifacts separate from pregnant women, and how a fetus thwarted Gertrude Stein's medical career. By resurrecting a nearly forgotten scientific project, Morgan sheds light on the roots of a modern origin story and raises the still controversial issue of how we decide what embryos mean.
In recent decades there has been an explosion in work in the social and physical sciences describing the similarities between human and nonhuman as well as human and non-animal thinking. In this work, Ruth Miller argues that these types of phenomena are also useful models for thinking about the growth, reproduction, and spread of political thought and democratic processes. By shifting her level of analysis from the politics of self-determining subjects to the realm of material environments and information systems, Miller asks what might happen if these alternative, nonhuman thought processes become the normative thought processes of democratic engagement.
Now that '3-D models’ are so often digital displays on flat screens, it is timely to look back at the solid models that were once the third dimension of science. This book is about wooden ships and plastic molecules, wax bodies and a perspex economy, monuments in cork and mathematics in plaster, casts of diseases, habitat dioramas, and extinct monsters rebuilt in bricks and mortar. These remarkable artefacts were fixtures of laboratories and lecture halls, studios and workshops, dockyards and museums. Considering such objects together for the first time, this interdisciplinary volume demonstrates how, in research as well as in teaching, 3-D models played major roles in making knowledge. Accessible and original chapters by leading scholars highlight the special properties of models, explore the interplay between representation in two dimensions and three, and investigate the shift to modelling with computers. The book is fascinating reading for anyone interested in the sciences, medicine, and technology, and in collections and museums.
Kaufman's Atlas of Mouse Development: With Coronal Sections continues the stellar reputation of the original Atlas by providing updated, in-depth anatomical content and morphological views of organ systems.The publication offers written descriptions of the developmental origins of the organ systems alongside high-resolution images for needed visualization of developmental processes. Matt Kaufman himself has annotated the coronal images in the same clear, meticulous style of the original Atlas. Kaufman's Atlas of Mouse Development: With Coronal Sections follows the original Atlas as a continuation of the standard in the field for developmental biologists and researchers across biological and biomedical sciences studying mouse development. - Provides high-resolution images for best visualization of key developmental processes and structures - Offers in-depth anatomy and morphological views of organ systems - Written descriptions convey developmental origins of the organ systems
Of mouse development -- Setting up a colony for the production of transgenic mice -- Recovery, culture, and transfer of embryos -- Introduction of new genetic information into the developing mouse embryo -- Iolation of pluripotential stem cell lines -- Techhniques for visualizing genes and gene products -- In vitro culture of eggs, embryos, and teratocarcinoma cels -- Chemicals, supplies, and solutions.
Hardly a day passes without newspaper coverage of some new development regarding prenatal life. The abortion debate continues to rage, but other examples abound: forced Caesareans; prosecutions of women for drug use during pregnancy; fetal protection policies; the use of fetal tissue for transplantation; embryo research; and the disposition of frozen embryos. All of these issues raise the question of the moral status of the unborn: are embryos and fetuses part of the pregnant woman or are they persons? Are they sources of tissue, research tools, or are they pre-born children? Different conceptions of the unborn prevail in different contexts, giving rise to the charge of inconsistency. For example, women have been criminally charged with abusing their fetuses by using drugs during pregnancy, even though abortion--which pro-lifers call the ultimate child abuse--is legal. The legalization of abortion itself was based in part on the unborn's never having been recognized in law as a full legal person. Yet fetuses have been considered as persons for the purposes of insurance coverage, wrongful death suits, and vehicular homicide. This book provides a framework for thinking clearly and coherently about the unborn. The first chapter elaborates the book's basic idea, that all and only beings who have interests have moral standing, and only beings who possess conscious awareness have interests. This thesis, which is called "the interest view," raises issues of considerable philosophical complexity, but is presented in language non-philosophers will be able to understand. Subsequent chapters apply the interest view, and explore the moral and legal aspects of a wide range of issues, including abortion, the legal status of the fetus outside abortion, maternal-fetal conflict, fetal research, and the use and disposition of extracorporeal embryos resulting from the new reproductive technologies. The philosophical discussion is enlivened by examples and actual cases which immediately catch, and sustain, the reader's interest. Written in a lively style, Life Before Birth: The Moral and Legal Status of Embryos and Fetuses is a timely and important work that enables us to resolve contradictions in our current thinking about the unborn, and to approach new issues in a clear and rational manner.
In vitro fertilization (IVF) and other assisted reproductive technologies (ART) have become a significant part of human reproduction, with already one in 50 children worldwide being born through ART and the demand steadily increasing. To accommodate the various kinds of infertility problems, new methods have been developed to increase IVF and ART success rates and it has also become possible to treat sperm, eggs, and embryos in culture to improve reproductive success, to increase the health state of an embryo, and to prevent disease in the developing child. Human Reproduction: Updates and New Horizons focuses on recent developments and new approaches to study egg and sperm cells and embryo development, as well as addressing the increasing demand for IVF and ART to overcome infertility problems of various kinds that are encountered by an increasing number of couples worldwide. The book includes 10 chapters written by experts in their specific fields to provide information on sperm selection techniques and their relevance to ART; In vitro maturation of human oocytes: current practices and future promises; Molecular biology of endometriosis; Novel immunological aspects for the treatment of age-induced ovarian and testicular infertility, other functional diseases, and early and advanced cancer immunotherapy; Mitochondrial manipulation for infertility treatment and disease prevention; Novel imaging techniques to assess gametes and preimplantation embryos; Clinical application of methods to select in vitro fertilized embryos; New horizons/developments in time-lapse morphokinetic analysis of mammalian embryos; The non-human primate model for early human development; Cytoskeletal functions, defects, and dysfunctions affecting human fertilization and embryo development. This book will appeal to a large interdisciplinary audience, including researchers from both the basic science and medical communities. It will be a valuable reference for IVF clinicians, patients and prospective patients who are considering ART procedures, embryologists, cell biologists and students in the field of reproduction.
Biological evolution is a fact—but the many conflicting theories of evolution remain controversial even today. When Adaptation and Natural Selection was first published in 1966, it struck a powerful blow against those who argued for the concept of group selection—the idea that evolution acts to select entire species rather than individuals. Williams’s famous work in favor of simple Darwinism over group selection has become a classic of science literature, valued for its thorough and convincing argument and its relevance to many fields outside of biology. Now with a new foreword by Richard Dawkins, Adaptation and Natural Selection is an essential text for understanding the nature of scientific debate.