Early Events in Diabetic Retinopathy and Intervention Strategies
Early Events in Diabetic Retinopathy and Intervention Strategies

Author: Andrew Tsin

Publisher: BoD – Books on Demand

Published: 2018-04-18

Total Pages: 104

ISBN-13: 1789230829

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The development of diabetic retinopathy is a long slow process affected by hyperglycemia, hypertension, lipid levels and genetics. It is expected that in 20 years' duration nearly all those with diabetes will exhibit diabetic retinopathy. In some patients, it will progress to blindness. While the number of individuals with diabetes increases, our current treatments are only effective at advanced levels of disease. Further, our screening methods to detect those needing treatment are currently not optimal. Early Events in Diabetic Retinopathy and Intervention Strategies covers topics addressing imaging processes currently available in the development of diabetic retinopathy screening. Potential biomarkers, that may be used to identify those at risk and illuminate the new pathways which lead to diabetic retinopathy, are expounded.

Early Events in Diabetic Retinopathy and Intervention Strategies
Early Events in Diabetic Retinopathy and Intervention Strategies

Author: Andrew T.C. Tsin

Publisher:

Published: 2018

Total Pages: 102

ISBN-13: 9781789230833

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The development of diabetic retinopathy is a long slow process affected by hyperglycemia, hypertension, lipid levels and genetics. It is expected that in 20 years' duration nearly all those with diabetes will exhibit diabetic retinopathy. In some patients, it will progress to blindness. While the number of individuals with diabetes increases, our current treatments are only effective at advanced levels of disease. Further, our screening methods to detect those needing treatment are currently not optimal. Early Events in Diabetic Retinopathy and Intervention Strategies covers topics addressing imaging processes currently available in the development of diabetic retinopathy screening. Potential biomarkers, that may be used to identify those at risk and illuminate the new pathways which lead to diabetic retinopathy, are expounded.

Clinical Strategies in the Management of Diabetic Retinopathy
Clinical Strategies in the Management of Diabetic Retinopathy

Author: Francesco Bandello

Publisher: Springer

Published: 2018-09-17

Total Pages: 300

ISBN-13: 3319961578

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The advent of intravitreal treatment with anti-vascular endothelium growth factor (anti-VEGF) antibodies and steroids has revolutionized the management of diabetic retinopathy. This timely 2nd edition delves into therapies involving anti-VEGF, and addresses the complexities inherent in the practical application of these clinical trials, from issues of patient compliance, to consideration of the patient’s overall health status. Clinical Strategies in the Management of Diabetic Retinopathy: Step-by-Step Guide for Ophthalmologists, 2nd Edition covers all the stages of diabetic retinopathy, including clinical manifestations, imaging, and treatment, from the early signs to more advanced levels of severity. Richly-illustrated, this clinical resource is designed to present multiple practical and useful suggestions for the management of each stage of diabetic retinopathy, using algorithms, tables, and summaries. Images of sample cases exemplify the effects of different therapies, including benefits and side effects. Novel perspectives in both imaging and treatment are provided to clearly outline current research in the field, with a look to future directions. Written and edited by well-respected leaders in the field, Clinical Strategies in the Management of Diabetic Retinopathy, 2nd edition is an ideal resource for ophthalmologists aiming to provide optimal clinical management for this sight-threatening disease.

Anti-Angiogenic Therapy in Ophthalmology
Anti-Angiogenic Therapy in Ophthalmology

Author: Andreas Stahl

Publisher: Springer

Published: 2016-05-13

Total Pages: 198

ISBN-13: 3319240978

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This book provides a concise overview over the pathology of retinal angiogenic diseases and explains why anti-angiogenic therapy is effective in so many patients. The reader is guided through the various clinical indications for anti-angiogenic therapy and made aware of its merits as well as current challenges and limitations. It is explained how, since its introduction for the treatment of exudative age-related macular degeneration in 2006, anti-angiogenic therapy has revolutionized the way in which we treat a range of ocular diseases. All of the authors are established experts in their respective fields who share their extensive knowledge and clinical experience with the reader. This book is both a valuable introduction to anti-angiogenic therapy in ophthalmology and a day-to-day companion for all ophthalmologists seeing patients with some of the most prevalent retinal diseases.

Intravitreal Steroids
Intravitreal Steroids

Author: Albert J. Augustin

Publisher: Springer

Published: 2015-02-19

Total Pages: 113

ISBN-13: 3319144871

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This book explains how to use intravitreal steroids optimally in the management of patients with intraocular inflammation (uveitis) and macular edema. The rationale for this treatment approach is first explained by examining the pathophysiology of these disease entities, with particular attention to the major role of inflammatory processes. Devices for the delivery of steroids to the eye are discussed, and guidance provided on the role of imaging studies before, during, and after steroid therapy. The value of different steroidal approaches is then considered in detail. Other topics addressed include the use of steroids as a surgical adjunct and within a combination strategy. Uveitis and macular edema are common sight-threatening diseases or complications of diabetes and retinal vein occlusion for which no adequate treatment was available until recently. Both trainees and practitioners will find Intravitreal Steroids to be an invaluable aid in combating these blinding diseases.

Management of Diabetic Retinopathy
Management of Diabetic Retinopathy

Author: F. Bandello

Publisher: Karger Medical and Scientific Publishers

Published: 2017-04-20

Total Pages: 206

ISBN-13: 3318060429

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Recently developed diagnostic and therapeutic technologies such as OCT-angiography and small gauge vitrectomy have influenced the modern treatment of diabetic retinopathy. This volume provides a summary of the state-of-the-art evidence-based approach to managing complications that may occur with diabetic retinopathy. It offers the latest information on pathogenesis and diagnosis, and highly experienced clinicians review the results of relevant randomized clinical trials that serve as the basis of current therapy. The book provides not only a summary of data from randomized trials but also an analysis and interpretation by internationally renowned experts. Ophthalmology residents, fellows, and practicing clinicians will find this book to be a useful reference when seeking evidence-based treatment strategies for various complications of diabetic retinopathy. It is also for researchers identifying new avenues of drug developments and for insurance professionals and health care policy administrators who are establishing evidence-based therapy guidelines for therapeutic intervention.

Diabetic Retinopathy
Diabetic Retinopathy

Author: Gloria Wu

Publisher: Lippincott Williams & Wilkins

Published: 2012-03-28

Total Pages: 272

ISBN-13: 1451153473

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Diabetic Retinopathy: The Essentials is written for general ophthalmologists and optometrists as well as family practitioners, diabetologists, and internists who encounter diabetic patients on a daily basis. It focuses on the diagnosis and management of diabetic retinopathy from the point of view of the retinal specialist. The book begins with the epidemiology, anatomy, and pathophysiology of diabetic retinopathy, and then covers important topics such as classification issues, diagnostic testing, examination techniques, new treatment modalities, patient management, indications for vitrectomy, pregnancy concerns, and informed consent. Coverage includes both general medical issues in diabetes and specifically ophthalmologic concerns. Features include more than 200 full-color photographs, case studies, and algorithms for patient management. A companion website includes the full text online and an image bank.

Diabetic Retinopathy
Diabetic Retinopathy

Author: Michael W. Stewart

Publisher: Springer

Published: 2017-04-07

Total Pages: 278

ISBN-13: 9811035091

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A well-illustrated and comprehensive analysis of the treatment of diabetic retinopathy, this book covers current treatment options and guidelines, whilst also providing a detailed discussion of emerging therapeutic targets. Existing therapeutic options are covered in depth, with a major focus on anti-vascular endothelial growth factor drugs and sustained release corticosteroids, including a review of trial results supporting current treatment guidelines. The use of agents off-label is also discussed. Controversial topics are discussed in detail with an emphasis on helping the reader make informed decisions, particularly when treating patients for which several treatment approaches may be appropriate because trial data does not clearly define the best option. Emerging therapeutic areas are evaluated, as work continues to identify agents that produce superior morphologic responses and visual acuity gains by targeting other molecules that contribute to diabetic retinopathy. Promising new drugs, targets and delivery systems are identified, and their development analysed.

Textbook of Vascular Medicine
Textbook of Vascular Medicine

Author: Rhian M. Touyz

Publisher: Springer

Published: 2019-08-02

Total Pages: 503

ISBN-13: 3030164810

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This textbook focuses on the vascular biology and physiology that underlie vascular disorders in clinical medicine. Vascular biomedicine is a rapidly growing field as new molecular mechanisms of vascular health and disease are unraveled. Many of the major cardiovascular diseases including coronary artery disease, heart failure, stroke and vascular dementia are diseases of the vasculature. In addition vascular injury underpins conditions like kidney failure and cardiovascular complications of diabetes. This field is truly multidisciplinary involving scientists in many domains such as molecular and vascular biology, cardiovascular physiology and pharmacology and immunology and inflammation. Clinically, specialists across multiple disciplines are involved in the management of patients with vascular disorders, including cardiologists, nephrologists, endocrinologists, neurologists and vascular surgeons. This book covers a wide range of topics and provides an overview of the discipline of vascular biomedicine without aiming at in-depth reviews, but rather offering up-to-date knowledge organized in concise and structured chapters, with key points and pertinent references. The structure of the content provides an integrative and translational approach from basic science (e.g. stem cells) to clinical medicine (e.g. cardiovascular disease). The content of this book is targeted to those who are new in the field of vascular biology and vascular medicine and is ideal for medical students, graduate and postgraduate students, clinical fellows and academic clinicians with an interest in the vascular biology and physiology of cardiovascular disease and related pathologies.

Disease Control Priorities, Third Edition (Volume 5)
Disease Control Priorities, Third Edition (Volume 5)

Author: Dorairaj Prabhakaran

Publisher: World Bank Publications

Published: 2017-11-17

Total Pages: 948

ISBN-13: 1464805202

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Cardiovascular, respiratory, and related conditions cause more than 40 percent of all deaths globally, and their substantial burden is rising, particularly in low- and middle-income countries (LMICs). Their burden extends well beyond health effects to include significant economic and societal consequences. Most of these conditions are related, share risk factors, and have common control measures at the clinical, population, and policy levels. Lives can be extended and improved when these diseases are prevented, detected, and managed. This volume summarizes current knowledge and presents evidence-based interventions that are effective, cost-effective, and scalable in LMICs.