Early detection and management of neurological serious adverse events in relation to the administration of anthelminthic medicines to people with asymptomatic neurocysticercosis

Early detection and management of neurological serious adverse events in relation to the administration of anthelminthic medicines to people with asymptomatic neurocysticercosis

Author: World Health Organization

Publisher: World Health Organization

Published: 2023-09-18

Total Pages: 8

ISBN-13: 9240068139

DOWNLOAD EBOOK

This document is designed for medical practitioners and programme staff working in preventive chemotherapy programs using praziquantel or multiple doses of albendazole in areas endemic or potentially endemic for T. solium. The objective of this document is to facilitate the training and awareness creation on the early identification of neurological serious adverse events and its management at the health centres. This is a derivative document from the PAHO/WHO Guideline for preventive chemotherapy for the control of T. solium taeniasis https://www.who.int/publications/i/item/9789275123720). It is based on the WHO mhGAP (https://www.who.int/publications/i/item/9789241549790) and complements the WHO publication on ‘Safety in administering medicines for neglected tropical diseases’ (https://www.who.int/publications/i/item/9789240024144). A poster has also been developed to accompany this document.


Global report on neglected tropical diseases 2024

Global report on neglected tropical diseases 2024

Author: World Health Organization

Publisher: World Health Organization

Published: 2024-05-04

Total Pages: 86

ISBN-13: 924009153X

DOWNLOAD EBOOK

This document is the second in a series of global reports describing progress towards the 2030 targets set in Ending the neglect to attain the Sustainable Development Goals: a road map for neglected tropical diseases 2021–2030. It describes a wide range of activities, accomplishments and challenges across the portfolio of NTDs and across all six WHO regions. The report presents epidemiological and programmatic data for 2022, which were gathered, compiled and analysed in 2023. In some cases, 2023 data are available and presented; in other cases, less recent information is included, when 2022 data are not available. In addition, it presents the main facts or events that occurred in 2023. In line with the road map’s companion document Ending the neglect to attain the Sustainable Development Goals: a framework for monitoring and evaluating progress of the road map for neglected tropical diseases 2021−2030, the report includes quantitative information on the status of the overarching, cross-cutting and disease-specific indicators. This is followed by qualitative information on each of the three road map pillars and on regional and country progress. The conclusions of the report and way forward are further complemented by annexes on cross-cutting indicator 6, status of donated medicines for treatment of NTDs, articles on NTDs published in the Weekly Epidemiological Record, target product profiles published as of 31 December 2023 and the list of global NTD reports published by WHO so far.


Neuroparasitology and Tropical Neurology

Neuroparasitology and Tropical Neurology

Author: Oscar H. Del Brutto

Publisher: Elsevier Inc. Chapters

Published: 2013-07-03

Total Pages: 38

ISBN-13: 012807969X

DOWNLOAD EBOOK

Cysticercosis, an infection caused by the cystic larvae of the pork tapeworm Taenia solium, is one of the most frequent parasitic infections of the human nervous system (neurocysticercosis). It is endemic in most of Latin America, the sub-Saharan Africa, and vast parts of Asia, including the Indian subcontinent. It has also been increasingly diagnosed in developed countries because of migration of people from endemic zones and exposure in travelers. The life cycle involves the development of the adult tapeworm in the human small intestine (after ingesting infected pork with cysts) and larval infection in pig tissues (after ingesting human stools containing the eggs of the tapeworm). Humans get infected by the fecal-oral route, most often from a direct contact with an asymptomatic Taenia carrier. Most common clinical presentations are seizures (particularly late-onset seizures), chronic headaches, and intracranial hypertension. However, cysticerci can locate anywhere in the human nervous system, thus potentially causing almost any neurological syndrome and making clinical diagnosis a difficult task. Neuroimaging is the main diagnostic tool, and specific serology confirms the diagnosis and helps to define the diagnosis when images are unclear. Factors such as location (extraparenchymal versus intraparenchymal), number, size and evolutive stage of the parasites determine the clinical manifestations, therapeutic approach, and prognosis. Management includes symptomatic drugs (analgesics, antiepileptic drugs, anti-inflammatory agents) and in many cases cysticidal drugs, either albendazole or praziquantel. In recent years, efforts have focused on transmission control and potential elimination in endemic regions.


Solitary Cysticercus Granuloma

Solitary Cysticercus Granuloma

Author: Rajshekhar

Publisher: Orient Blackswan

Published: 2000

Total Pages: 184

ISBN-13: 9788125016212

DOWNLOAD EBOOK

Solitary Cysticercus Granuloma Is One Of The Most Common Parasitic Diseases Of The Brain. This Monograph Is The Outcome Of Research Undertaken At Cmc, Vellore. It Also Takes Into Account Recent Work In Other Parts Of The World. The Contributors Include Neurologists, Neurosurgeons, Neurochemists And Neuropathologists.


Investing to Overcome the Global Impact of Neglected Tropical Diseases

Investing to Overcome the Global Impact of Neglected Tropical Diseases

Author: World Health Organization

Publisher: World Health Organization

Published: 2015-08-05

Total Pages: 211

ISBN-13: 9241564865

DOWNLOAD EBOOK

"The presence, or absence, of neglected tropical diseases (NTDs) can be seen as a proxy for poverty and for the success of interventions aimed at reducing poverty. Today, coverage of the public-health interventions recommended by the World Health Organization (WHO) against NTDs may be interpreted as a proxy for universal health coverage and shared prosperity - in short, a proxy for coverage against neglect. As the world's focus shifts from development to sustainable development, from poverty eradication to shared prosperity, and from disease-specific goals to universal health coverage, control of NTDs will assume an important role towards the target of achieving universal health coverage, including individual financial risk protection. Success in overcoming NTDs is a "litmus test" for universal health coverage against NTDs in endemic countries. The first WHO report on NTDs (2010) set the scene by presenting the evidence for how these interventions had produced results. The second report (2013) assessed the progress made in deploying them and detailed the obstacles to their implementation. This third report analyses for the first time the investments needed to achieve the scale up of implementation required to achieve the targets of the WHO Roadmap on NTDs and universal coverage against NTDs. INVESTING TO OVERCOME THE GLOBAL IMPACT OF NEGLECTED TROPICAL DISEASES presents an investment strategy for NTDs and analyses the specific investment case for prevention, control, elimination and eradication of 12 of the 17 NTDs. Such an analysis is justified following the adoption by the Sixty-sixth World Health Assembly in 2013 of resolution WHA6612 on neglected tropical diseases, which called for sufficient and predictable funding to achieve the Roadmap's targets and sustain control efforts. The report cautions, however, that it is wise investment and not investment alone that will yield success. The report registers progress and challenges and signals those that lie ahead. Climate change is expected to increase the spread of several vector-borne NTDs, notably dengue, transmission of which is directly influenced by temperature, rainfall, relative humidity and climate variability primarily through their effects on the vector. Investments in vector-borne diseases will avoid the potentially catastrophic expenditures associated with their control. The presence of NTDs will thereby signal an early warning system for climate-sensitive diseases. The ultimate goal is to deliver enhanced and equitable interventions to the most marginalized populations in the context of a changing public-health and investment landscape to ensure that all peoples affected by NTDs have an opportunity to lead healthier and wealthier lives."--Publisher's description.


Current State of the Art in Cysticercosis and Neurocysticercosis

Current State of the Art in Cysticercosis and Neurocysticercosis

Author: Jorge Morales-Montor

Publisher: BoD – Books on Demand

Published: 2021-11-10

Total Pages: 147

ISBN-13: 1839693940

DOWNLOAD EBOOK

This book provides updated information to scientists and clinicians on taeniosis/cysticercosis, a parasitic infection caused by eating undercooked beef or pork that is a serious health and veterinary problem in many developing countries. It discusses incidence, risk factors, diagnosis, immunology, symptoms, rare manifestations, and advances in treatment including vaccination and novel drug therapies.


Working to Overcome the Global Impact of Neglected Tropical Diseases

Working to Overcome the Global Impact of Neglected Tropical Diseases

Author: World Health Organization. Department of Control of Neglected Tropical Diseases

Publisher: World Health Organization

Published: 2010

Total Pages: 184

ISBN-13: 9241564091

DOWNLOAD EBOOK

"Neglected tropical diseases (NTDs) blight the lives of a billion people worldwide and threaten the health of millions more. These ancient companions of poverty weaken impoverished populations, frustrate the achievement of health in the Millennium Development Goals and impede global health and economies has convinced governments, donors, the pharmaceutical industry and other agencies, including nongovernmental organizations (NGOs), to invest in preventing and controlling this diverse group of diseases. Global efforts to control "hidden" diseases, such as dracunculiasis (guinea-worm disease), leprosy, gains including the imminent eradication of dracunculiasis. Since 1989 (when most endemic countries began reporting monthly from each endemic village), the number of new dracunculiasis cases has fallen from 892 055 in 12 endemic countries to 3190 in 4 countries in 2009, a decrease of more than 99%. The World Health Organization (WHO) recommends five public-health strategies for the prevention and control of NTDs: preventive chemotherapy; intensified case-management; vector control; the provision of safe water, sanitation and hygiene; and veterinary public health (that is, applying veterinary sciences to ensure the health and well-being of humans). Although one approach and delivered locally." - p. vii


Imaging in Neurology E-Book

Imaging in Neurology E-Book

Author: Anne G. Osborn

Publisher: Elsevier Health Sciences

Published: 2016-04-20

Total Pages: 527

ISBN-13: 0323448291

DOWNLOAD EBOOK

Written by two renowned leaders in neuroradiology and neurology, this unique reference is a high-level imaging resource ideal for today's clinical neurologist or neuroscientist. Using straightforward, jargon-free prose, this book provides an overview of neurological disorders coupled with typical imaging findings — all designed for use at the point of care. You will be expertly guided throughout, from radiologic appearance and the significance of the imaging findings to the next appropriate steps in effective patient care. - Discusses radiologic appearances of common neurological diseases, their significance, and the next steps in patient care in a clear manner perfectly suited for neurologists or neuroscientists - Provides high-level information from both a neuroradiologist and a neurologist, making it a balanced and appropriate clinical reference for day-to-day neurology practice - Covers imaging in stroke, infectious disease, brain malformations, tumors, and more - Keeps you up-to-date with unusual emerging neurologic disorders, such as Susac syndrome, West Nile Virus, and IRIS


Echography and Doppler of the Brain

Echography and Doppler of the Brain

Author: Chiara Robba

Publisher: Springer Nature

Published: 2020-10-03

Total Pages: 319

ISBN-13: 3030482022

DOWNLOAD EBOOK

The aim of this book is to educate and train practitioners in the safe and professional use of diagnostic ultrasound imaging in the visualization and interpretation of various cerebral conditions not only in neurointensive care, but also in the operating room and, in general, cardiothoracic and neurocritical care settings. It is chiefly intended for anaesthetists and intensivists with a basic knowledge of ultrasound physics, but also for neurosurgeons and neurologists. All chapters were coordinated by the Editors, with experiences in hands-on courses on Echography and Doppler of the Brain, and prepared by international experts. The book covers from basic principles to estimation of intracranial pressure and cerebral perfusion. The topics cover emergency department and prehospital brain US as part of POCUS and US multiorgan evaluation to general intensive care, neurointensive care and anesthesia, including special populations as pregnant and children and setting as LMIC. Clinical scenarios complete the book. An innovative and unique guide that equips readers to perform bedside and non-invasive assessments for a range of cerebrovascular diseases.