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Author: JAY D. KEASLING
Publisher:
Published: 1991
Total Pages: 270
ISBN-13:
DOWNLOAD EBOOKorigin contributes in some way to the cell-cycle-specific replication behavior of the F plasmid.
Author: Sang Yup Lee
Publisher: Springer Science & Business Media
Published: 2009-03-20
Total Pages: 471
ISBN-13: 1402093942
DOWNLOAD EBOOKSystems biology is changing the way biological systems are studied by allowing us to examine the cell and organism as a whole. Systems biotechnology allows optimal design and development of upstream to downstream bioprocesses by taking a systems-approach. E. coli has been a model organism for almost all biological and biotechnological studies. This book brings together for the first time the state-of-the-art reviews by the world-leading experts on systems biology and biotechnological applications of E. coli. The topics covered include genomics and functional genomics, resources for systems biology, network analysis, genome-scale metabolic reconstruction, modelling and simulation, dynamic modelling and simulation, systems-level analysis of evolution, plasmids and expression systems, protein synthesis, production and export, engineering the central metabolism, synthetic biology, and systems metabolic engineering of E. coli. This book provides readers with guidance on how a complex biological system can be studied using E. coli as a model organism. It also presents how to perform synthetic biology and systems metabolic engineering studies on E. coli with successful examples, the approaches of which can be extended to other organisms. This book will be a complete resource for anyone interested in systems biology and biotechnology.
Author: Marcelo E. Tolmasky
Publisher: John Wiley & Sons
Published: 2020-07-24
Total Pages: 720
ISBN-13: 1555818986
DOWNLOAD EBOOKExplore the remarkable discoveries in the rapidly expanding field of plasmid biology Plasmids are integral to biological research as models for innumerable mechanisms of living cells, as tools for creating the most diverse therapies, and as crucial helpers for understanding the dissemination of microbial populations. Their role in virulence and antibiotic resistance, together with the generalization of "omics" disciplines, has recently ignited a new wave of interest in plasmids. This comprehensive book contains a series of expertly written chapters focused on plasmid biology, mechanistic details of plasmid function, and the increased utilization of plasmids in biotechnology and pharmacology that has occurred in the past decade. Plasmids: Biology and Impact in Biotechnology and Discovery serves as an invaluable reference for researchers in the wide range of fields and disciplines that utilize plasmids and can also be used as a textbook for upper-level undergraduate and graduate courses in biotechnology and molecular biology.
Author: Peter Mullany
Publisher: Cambridge University Press
Published: 2005-09-26
Total Pages: 452
ISBN-13: 9780521821575
DOWNLOAD EBOOK"This book provides an in-depth analysis of the mechanisms and biological consequences of genome rearrangements in bacteria. Each chapter examines the mechanisms involved in genome rearrangements and the direct biological consequences of these events. Because genome rearrangements are so important in evolution, at least one of the chapters views the phenomenon from an evolutionary angle. This book provides the reader with a holistic view of genome rearrangements (i.e., studies on both the biological consequences of genome rearrangement and the mechanisms underlying these processes are presented)." "The book is written by leading research workers in the field and is aimed at final-year undergraduates, postgraduate and postdoctoral workers, and established biologists."--BOOK JACKET.
Author: Christopher M. Thomas
Publisher: CRC Press
Published: 2003-09-02
Total Pages: 459
ISBN-13: 0203304330
DOWNLOAD EBOOKBacteria are the most ubiquitous of all organisms. Responsible for a number of diseases and for many of the chemical cycles on which life depends, they are genetically adaptable. Vital to this adaptability is the existence of autonomous genetic elements-plasmids-which promote genetic exchange and recombination. The genes carried by any particular plasmid may be found in only a few individuals of any species but can also be shared with other species and thus constitute a horizontal gene pool. This book explains the various contributions that plasmids make to this pool: the replication, stable inheritance and transfer modules, the phenotypic markers they carry, the way they evolve, the ways they contribute to their host population and the approaches that we use to study and classify them. It also looks at what we know about their activity in natural communities and the way that they interact with other mobile elements to promote bacterial evolution.
Author: Paulina Balbas
Publisher: Springer Science & Business Media
Published: 2008-02-04
Total Pages: 505
ISBN-13: 1592597742
DOWNLOAD EBOOKSince newly created beings are often perceived as either wholly good or bad, the genetic alteration of living cells impacts directly on a symbolic meaning deeply imbedded in every culture. During the earlier years of gene expression research, te- nological applications were confined mainly to academic and industrial laboratories, and were perceived as highly beneficial since molecules that were previously unable to be separated or synthesized became accessible as therapeutic agents. Such were the success stories of hormones, antibodies, and vaccines produced in the bacterium Escherichia coli. Originally this bacterium gained fame among humans for being an unwanted host in the intestine, or worse yet, for being occasionally dangerous and pathogenic. H- ever, it was easily identified in contaminated waters during the 19th century, thus becoming a clear indicator of water pollution by human feces. Tamed, cultivated, and easily maintained in laboratories, its fast growth rate and metabolic capacity to adjust to changing environments fascinated the minds of scientists who studied and modeled such complex phenomena as growth, evolution, genetic exchange, infection, survival, adaptation, and further on—gene expression. Although at the lower end of the complexity scale, this microbe became a very successful model system and a key player in the fantastic revolution kindled by the birth of recombinant DNA technology.
Author: Peter Mullany
Publisher: Cambridge University Press
Published: 2010-02-04
Total Pages: 454
ISBN-13: 1139445502
DOWNLOAD EBOOKThe genetic information contained in DNA is not static, especially in bacterial DNA. It is capable of recombining with other DNA sequences and transferring to other bacteria. These processes allow bacteria to rapidly respond to their environment and are also important in production of disease and the spread of antibiotic resistance. This book is concerned with the mechanisms underlying these dynamic processes in bacterial DNA.
Author: Edward Schwartz
Publisher: Springer Science & Business Media
Published: 2009-01-29
Total Pages: 348
ISBN-13: 3540854673
DOWNLOAD EBOOKMegaplasmids are extrachromosomal genetic elements in the size range of 100 kb and larger. They are found in physiologically and phylogenetically diverse groups of bacteria and archaea. By definition, megaplasmids are not essential for the viability of their hosts under all growth conditions, but paradoxically many megaplasmids carry the genetic information for the defining and characteristic traits of the organism in which they reside. Microbial Megaplasmids reviews our knowledge of the extensively studied representatives, such as the catabolic plasmids of the pseudomonads, the rhizobial Sym plasmids, the Ti plasmids of the genus Agrobacterium and the giant enterobacterial virulence plasmids. It also presents snapshots of more recently discovered megaplasmids. The contribution of megaplasmids to the biology of their hosts is described, highlighting the interactions between megaplasmid and chromosomal genes.
Author: Frederick C. Neidhardt
Publisher:
Published: 1996
Total Pages: 2822
ISBN-13: 9781555810849
DOWNLOAD EBOOKThis is the long–awaited second edition of an invaluable classic! Escherichia coli occupies a central role in contemporary molecular biology. It is the unicellular organism about which most is known – all molecular and cellular biologists will want a copy of this book. In 154 chapters, 250 expert authors and editors present the state of the art. Completely rewritten and restructured, the second edition offers a whole new approach to the subject.
Author: Donald R. Helinski
Publisher: Springer Science & Business Media
Published: 2012-12-06
Total Pages: 982
ISBN-13: 1461324475
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