DttP.
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Published: 1999
Total Pages: 80
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Author: Arthur Kornberg
Publisher: University Science Books
Published: 2005-06-24
Total Pages: 964
ISBN-13: 9781891389443
DOWNLOAD EBOOKDNA Replication, second edition, a classic of modernscience, is now back in print in a paperback edition. Kornberg and Baker'sinsightful coverage of DNA replication and related cellular processes have madethis the standard reference in the field.
Author: David Greenberg
Publisher: Elsevier
Published: 2012-12-02
Total Pages: 513
ISBN-13: 0323162134
DOWNLOAD EBOOKMetabolic Pathways, Third Edition: Volume IV: Nucleic Acids, Protein Synthesis, and Coenzymes focuses on the metabolic pathways of the major biological constituents of living organisms, namely, nucleic acids, proteins, and coenzymes. The biosynthesis and metabolism of purines and pyrimidines, nucleotides, riboflavin and related compounds, and vitamin B6 are discussed. The biogenesis and metabolism of thiamine and folic acid are also considered. This volume is comprised of seven chapters and begins with an analysis of metabolic control and enzymology of purines and pyrimidines such as inosinic acid and nucleotides. The next chapter is devoted to the biosynthesis and metabolism of nucleotides and nucleic acids, making reference to deoxyribonucleotides as well as RNA and DNA. Some of the reactions involving nucleotides are classified and briefly discussed. The reader is then introduced to protein synthesis, paying particular attention to the chemical features of the synthesis of the peptide bond and the characteristics of the genetic code implicated in this process. The remaining chapters focus on riboflavin and related compounds, thiamine, folic acid, and vitamin B6. This book will be a useful resource for biochemists and biologists.
Author: Ying Zhang
Publisher: Springer Science & Business Media
Published: 2012-01-25
Total Pages: 738
ISBN-13: 3642273262
DOWNLOAD EBOOKThis volume contains revised and extended research articles written by prominent researchers participating in the ICF4C 2011 conference. 2011 International Conference on Future Communication, Computing, Control and Management (ICF4C 2011) has been held on December 16-17, 2011, Phuket, Thailand. Topics covered include intelligent computing, network management, wireless networks, telecommunication, power engineering, control engineering, Signal and Image Processing, Machine Learning, Control Systems and Applications, The book will offer the states of arts of tremendous advances in Computing, Communication, Control, and Management and also serve as an excellent reference work for researchers and graduate students working on Computing, Communication, Control, and Management Research.
Author: Chris H. De Bruyn
Publisher: Springer Science & Business Media
Published: 2013-06-29
Total Pages: 517
ISBN-13: 1475703902
DOWNLOAD EBOOKThese two volumes, entitled "Purine Metabolism in Man IV" con tain the papers presented at the Fourth International Symposium on Human Purine and Pyrimidine Metabolism", held in Maastricht (The Netherlands), June 1982. The proceedings of the three previous meet ings in Tel Aviv (Israel, 1973), Baden (Austria, 1976) and Madrid (Spain, 1979) were also published by Plenum Press. In the past few years interest in purine and pyrimidine metabo lism under normal and pathological conditions has been growing rapid ly. Apart from the more or less classical topics such as hyperuricae mia, clinical gout and urolithiasis, an increasing number of papers relating to other fields have been presented at successive meetings. Knowledge derived from the study of purine metabolism in relation to lymphocyte function, for instance, has opened up new possibilities for immunomodulation and leukaemia chemotherapy, with eventual conse quences for other types of cancer. At previous meetings there have been pointers implicating purine metabolism in relation to normal cardiac and skeletal muscle function. During the present meeting mych new data on both issues have been re ported which indicate clear differences in the pathways of ATP metabo lism. The widening of the field of interest is also illustrated by the recent work on infectious disease: exploitation of the differences in purine metabolic pathways in certain parasites compared with those in human cells has resulted in new rationales for therapy being devel oped.
Author: Geir Slupphaug
Publisher: World Scientific
Published: 2018-07-25
Total Pages: 303
ISBN-13: 9813233516
DOWNLOAD EBOOKThis book describes genomic uracil in evolution, as a DNA constituent in adaptive and innate immune responses and as a mutagenic lesion causing cancer. Genomic uracil is as old as life and may have been a component in self-replicating molecules in the prebiotic era. The first living cells probably contained uracil in DNA, later to be replaced by thymine. The pioneering work of Nobel Laureate, Tomas Lindahl on spontaneous deamination of DNA cytosine to uracil was followed by his discovery of uracil-DNA glycosylase, which initiates repair of genomic uracil in base excision repair (BER). Uracil-DNA glycosylases are found in all forms of life and in DNA viruses, having roles in DNA repair, replication and epigenetics. The surprising discovery of enzymatic DNA cytosine deamination by the AID/APOBEC deaminases subsequently has implicated genomic uracil in the development of human cancer. The aim of the book is to contribute a reference text for graduate students, molecular biologists, immunologists and cancer biologists.Genomic uracil has become a hot research topic of wide interest after the Nobel Prize in Chemistry 2015 was awarded for DNA repair (Paul Modrich, Aziz Sancar and Tomas Lindahl). Furthermore, genomic uracil has received wide interest among both immunologists and cancer biologists due to its unexpected and fundamental role in adaptive immunity. Genomic uracil, thus, is highly relevant to researchers in different areas of research, but to our knowledge there is no published text that treats genomic uracil in an interdisciplinary way. The authors of this book have in the last three decades worked on genomic uracil and its processing and are among the most highly cited authors in the field.
Author: Bernard L. Horecker
Publisher: Elsevier
Published: 2014-06-28
Total Pages: 337
ISBN-13: 1483217183
DOWNLOAD EBOOKCurrent Topics in Cellular Regulation, Volume 19 analyzes the advances in the general area of cellular regulation. This book discusses the evidence indicating that synthesis of the histidine enzymes is regulated and drugs affecting ribonucleotide reductase. The analogy principle in comparative biochemistry of allosteric regulation of metabolism, steady-state model of glucose metabolism in adipose tissue, and sensitivity of enzyme activity to changing ion concentrations are also elaborated. This publication likewise covers the cAMP-dependent protein kinases of nervous tissue and amino acid sequences of IGF I and II. This volume is a good reference for biologists and researchers conducting work on the basic mechanisms involved in the regulation of diverse cellular activities.
Author: Bart Rijnders
Publisher: Leuven University Press
Published: 2003
Total Pages: 146
ISBN-13: 9789058673404
DOWNLOAD EBOOK"In modern-day medicine, the use of intravascular catheters has become unavoidable. In the United States, hospitals and clinics purchase more than 150 million intravascular devices each year of which more than 5 million are central venous catheters (CVC). "
Author: Lawrence C. Kuo
Publisher: Elsevier
Published: 1996
Total Pages: 698
ISBN-13: 9780121821760
DOWNLOAD EBOOKThe critically acclaimed laboratory standard for more than forty years, Methods in Enzymology is one of the most highly respected publications in the field of biochemistry. Since 1955, each volume has been eagerly awaited, frequently consulted, and praised by researchers and reviewers alike. More than 270 volumes have been published (all of them still in print) and much of the material is relevant even today--truly an essential publication for researchers in all fields of life sciences. Key Features* Expression, purification, and characterization* Activity assays* Kinetic and screening* Design and analysis of substrates and inhibitors* Molecular and structural characterizations.