Drinking Coffee, Mate, and Very Hot Beverages

Drinking Coffee, Mate, and Very Hot Beverages

Author: International Agency for Research on Cancer

Publisher:

Published: 2019-05

Total Pages: 504

ISBN-13: 9789283201540

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This volume of the IARC Monographs presents evaluations of the carcinogenic hazard to humans of drinking coffee and very hot beverages including, but not limited to, mate. An IARC Monographs Working Group reviewed epidemiological evidence, animal bioassays and co-carcinogenicity studies, and mechanistic and other relevant data to reach conclusions as to the carcinogenic hazard to humans of drinking coffee, mate, and very hot beverages. The Working Group assessed more than 1000 observational and experimental studies that investigated the association between cancer at more than 20 sites with drinking coffee, mate, and very hot beverages.


Some Chemicals Present in Industrial and Consumer Products, Food and Drinking-water

Some Chemicals Present in Industrial and Consumer Products, Food and Drinking-water

Author: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Publisher: IARC Monographs on the Evaluat

Published: 2013

Total Pages: 0

ISBN-13: 9789283213246

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This volume of the IARC Monographs provides an assessment of the carcinogenicity of 18 chemicals present in industrial and consumer products or food (natural constituents, contaminants, or flavorings) or occurring as water-chlorination by-products. The compounds evaluated include the widely used plasticizer di(2-ethylhexyl) phthalate and the food contaminant 4-methylimidazole. In view of the limited agent-specific information available from epidemiological studies, the IARC Monographs Working Group relied mainly on carcinogenicity bioassays, and mechanistic and other relevant data to evaluate the carcinogenic hazards to humans exposed to these agents.


Red Meat and Processed Meat

Red Meat and Processed Meat

Author: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Publisher: International Agency for Research on Cancer

Published: 2018-07-27

Total Pages: 0

ISBN-13: 9789283201526

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This volume of the IARC Monographs provides evaluations of the consumption of red meat and the consumption of processed meat. Red meat refers to unprocessed mammalian muscle meat (e.g. beef, veal, pork, lamb) including that which may be minced or frozen. Processed meat refers to meat that has been transformed through salting, curing, fermentation, smoking or other processes to enhance flavor or improve preservation. Most processed meats contain pork or beef, but may also contain other meats including poultry and offal (e.g. liver) or meat by-products such as blood. Red meat contains proteins of high biological value, and important micronutrients such as B vitamins, iron (both free iron and haem iron), and zinc. Carcinogens, including heterocyclic aromatic amines and polycyclic aromatic hydrocarbons, can be produced by cooking of meat, with greatest amounts generated at high temperatures by pan-frying, grilling, or barbecuing. Meat processing such as curing and smoking can result in formation of carcinogenic chemicals including N-nitroso compounds and polycyclic aromatic hydrocarbons. An IARC Monographs Working Group reviewed epidemiological evidence, animal bioassays, and mechanistic and other relevant data to reach conclusions as to the carcinogenic hazard to humans of the consumption of red meat and processed meat. The Working Group assessed more than 800 epidemiological studies that investigated the association of cancer (more than 15 types) with consumption of red meat or processed meat, including large cohorts in many countries, from several continents, with diverse ethnicities and diets.


Some Naturally Occurring Substances

Some Naturally Occurring Substances

Author: IARC Working Group on the Evaluation of Carcinogenic Risks to Humans

Publisher: World Health Organization

Published: 1993

Total Pages: 612

ISBN-13:

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Evaluates the carcinogenic risk to humans posed by the ingestion of several naturally occurring substances. Separate monographs are presented for two food items (salted fish and pickled vegetables), two naturally occurring plant substances (caffeic acid and d-limonene), four heterocyclic aromatic amines found in cooked meat and fish, and selected mycotoxins, including aflatoxins. The monograph on salted fish concentrates on fish as traditionally prepared in southern China, where very high rates of nasopharyngeal carcinoma have been linked to the consumption of salted fish prepared in a manner which involves putrefaction. The monograph concludes that Chinese-style salted fish is carcinogenic to humans. The second monograph concludes that pickled vegetables prepared according to traditional Asian methods are possibly carcinogenic to humans. Caffeic acid was judged to be possibly carcinogenic to humans. The report was unable to classify the carcinogenicity of d-limonene. For the heterocyclic aromatic amines present in cooked meat and fish, IQ was classified as probably carcinogenic to humans; MeIQ MeIQx and PhIP were classified as possibly carcinogenic. The most extensive monograph on aflatoxins concludes that naturally occurring mixtures of aflatoxins are carcinogenic to humans and that aflatoxin M1 occurring in milk is possibly carcinogenic. Toxins derived from Fusarium moniliforme and ochratoxin A, which has been linked to Balkan endemic nephropathy, were classified as possibly carcinogenic to humans. The remaining mycotoxins could not be classified.


The Dictionary of Substances and their Effects (DOSE)

The Dictionary of Substances and their Effects (DOSE)

Author: S D Gangolli

Publisher: Royal Society of Chemistry

Published: 2007-10-31

Total Pages: 974

ISBN-13: 1847559344

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This new edition of The Dictionary and Substances and their Effects (DOSE) supersedes the renowned 1st edition. The 1st edition has been completely revised, updated and extended with all the latest significant data on the chemicals known to have adverse effects on lifeforms or the environment. The new edition is a must for all those who need easy access to a single source of the latest essential and fully referenced data on chemicals which are known to have significant toxic or environmental effects. The web database is ideal for targeted searches and customised data retrieval. The 2nd edition of DOSE includes new toxicity, environmental and regulatory data from the world's literature, presented in concise summaries. These new data are essential for the accurate assessment of the risks associated with the use and disposal of chemicals. Data on over 100 chemicals new to this edition have been added, including endocrine disruptors, food carcinogens, pesticides and compounds studied by IARC and NTP. All of the 4000 chemicals contained in the 1st edition have been reviewed. New and updated information for these chemicals includes: * occupational exposure limits for 6 countries * recent toxicity and ecotoxicity data * results of new carcinogenicity, mutagenicity and environmental fate studies * the latest regulatory requirements DOSE 2nd edition comprises 7 hardcover volumes covering over 4000 chemicals alphabetically, and includes indexes of substance names and synonyms, molecular formulae, and CAS Registry Numbers; glossaries of medical terms and Latin to English organism names; an abbreviations listing and a comprehensive guide to the types of data and their origin. DOSE is also available via Knovel's Engineering and Scientific Online Reference, located at www.knovel.com.


New Frontiers of Cancer Causation

New Frontiers of Cancer Causation

Author: Iversen

Publisher: CRC Press

Published: 1993-08-01

Total Pages: 486

ISBN-13: 9781560322511

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Proceedings of the Second International Conference on Theories of Carcinogenesis, held in Oslo, Norway, August 1992. The papers, which discuss principles and theories rather than experimental setups and results, cover a wide range of topics, including cell proliferation, metastasis, oncogenes, carcinogens, genetic alterations, viruses, immunology, and radiation. Also detailed are public attitudes toward cancer, as well as attitudes of professionals in cancer research. The volume concludes with some brief considerations from speakers and participants. Annotation copyright by Book News, Inc., Portland, OR