Diffusion Processes and Related Topics in Biology

Diffusion Processes and Related Topics in Biology

Author: Luigi M. Ricciardi

Publisher: Springer Science & Business Media

Published: 2013-03-13

Total Pages: 207

ISBN-13: 364293059X

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These notes are based on a one-quarter course given at the Department of Biophysics and Theoretical Biology of the University of Chicago in 1916. The course was directed to graduate students in the Division of Biological Sciences with interests in population biology and neurobiology. Only a slight acquaintance with probability and differential equations is required of the reader. Exercises are interwoven with the text to encourage the reader to play a more active role and thus facilitate his digestion of the material. One aim of these notes is to provide a heuristic approach, using as little mathematics as possible, to certain aspects of the theory of stochastic processes that are being increasingly employed in some of the population biol ogy and neurobiology literature. While the subject may be classical, the nov elty here lies in the approach and point of view, particularly in the applica tions such as the approach to the neuronal firing problem and its related dif fusion approximations. It is a pleasure to thank Professors Richard C. Lewontin and Arnold J.F. Siegert for their interest and support, and Mrs. Angell Pasley for her excellent and careful typing. I . PRELIMINARIES 1. Terminology and Examples Consider an experiment specified by: a) the experiment's outcomes, ~, forming the space S; b) certain subsets of S (called events) and by the probabilities of these events.


Current Catalog

Current Catalog

Author: National Library of Medicine (U.S.)

Publisher:

Published:

Total Pages: 1568

ISBN-13:

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First multi-year cumulation covers six years: 1965-70.


Mathematical Demography

Mathematical Demography

Author: D. Smith

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 493

ISBN-13: 3642810462

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This volume is an effort to bring together important contributions to the mathe matical development of demography and to suggest briefly their historical context. We have tried to find who first thought of the several concepts and devices commonly used by demographers, what sort of problem he was facing to which the device or concept seemed the solution, and how his invention developed subsequently in the hands of others. Historically, the book starts with a Roman table of life expectancies from the third century a. d. about which we know little, and with John Graunt's explora tions in an area that was still popularly suspect when he wrote in 1662. These are followed by the astronomer Halley, who looked into the field long enough to invent the life table and to notice that Their Majesties would take a sizeable loss on the annuity scheme they had just launched; and by Euler, who was first to devise the formulas of stable population theory and to apply them to filling gaps in data To these we add the handful of further contributions in the 19th century and many pieces from the explosion of contributions that began in this century with Lotka. We doubt that we have managed to trace everything back to its ultimate beginning, and suspect that our nominees in some cases have been anticipated by predecessors who will be turned up by other students.


Spectral Analysis, Differential Equations and Mathematical Physics: A Festschrift in Honor of Fritz Gesztesy's 60th Birthday

Spectral Analysis, Differential Equations and Mathematical Physics: A Festschrift in Honor of Fritz Gesztesy's 60th Birthday

Author: Helge Holden

Publisher: American Mathematical Soc.

Published: 2013-07-08

Total Pages: 409

ISBN-13: 0821875744

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This volume contains twenty contributions in the area of mathematical physics where Fritz Gesztesy made profound contributions. There are three survey papers in spectral theory, differential equations, and mathematical physics, which highlight, in particu


Systems Theory in Immunology

Systems Theory in Immunology

Author: C. Bruni

Publisher: Springer Science & Business Media

Published: 2013-03-08

Total Pages: 286

ISBN-13: 3642931308

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This volume collects the contributions presented at the "Working Conference on System Theory in Immunology", held in Rome, May 1978. The aim of the Conference was to bring together immunologists on one side and experts in system theory and applied mathematics on the other, in order to identify problems of common interest and to establish a network of joint effort toward their solution. The methodologies of system theory for processing experimental data and for describing dynamical phenomena could indeed contribute significantly to the under standing of basic immunological facts. Conversely, the complexity of experimental results and of interpretative models should stimulate mathematicians to formulate new problems and to design appropriate procedures of analysis. The multitude of scientific publications in theoretical biology, appeared in recent years, confirms this trend and calls for extensive interaction between mat- matics and immunology. The material of this volume is divided into five sections, along the scheme of the Conference program.


Partitions, Hypergeometric Systems, and Dirichlet Processes in Statistics

Partitions, Hypergeometric Systems, and Dirichlet Processes in Statistics

Author: Shuhei Mano

Publisher: Springer

Published: 2018-07-12

Total Pages: 140

ISBN-13: 4431558888

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This book focuses on statistical inferences related to various combinatorial stochastic processes. Specifically, it discusses the intersection of three subjects that are generally studied independently of each other: partitions, hypergeometric systems, and Dirichlet processes. The Gibbs partition is a family of measures on integer partition, and several prior processes, such as the Dirichlet process, naturally appear in connection with infinite exchangeable Gibbs partitions. Examples include the distribution on a contingency table with fixed marginal sums and the conditional distribution of Gibbs partition given the length. The A-hypergeometric distribution is a class of discrete exponential families and appears as the conditional distribution of a multinomial sample from log-affine models. The normalizing constant is the A-hypergeometric polynomial, which is a solution of a system of linear differential equations of multiple variables determined by a matrix A, called A-hypergeometric system. The book presents inference methods based on the algebraic nature of the A-hypergeometric system, and introduces the holonomic gradient methods, which numerically solve holonomic systems without combinatorial enumeration, to compute the normalizing constant. Furher, it discusses Markov chain Monte Carlo and direct samplers from A-hypergeometric distribution, as well as the maximum likelihood estimation of the A-hypergeometric distribution of two-row matrix using properties of polytopes and information geometry. The topics discussed are simple problems, but the interdisciplinary approach of this book appeals to a wide audience with an interest in statistical inference on combinatorial stochastic processes, including statisticians who are developing statistical theories and methodologies, mathematicians wanting to discover applications of their theoretical results, and researchers working in various fields of data sciences.


The Handbook of Brain Theory and Neural Networks

The Handbook of Brain Theory and Neural Networks

Author: Michael A. Arbib

Publisher: MIT Press

Published: 2003

Total Pages: 1328

ISBN-13: 0262011972

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This second edition presents the enormous progress made in recent years in the many subfields related to the two great questions : how does the brain work? and, How can we build intelligent machines? This second edition greatly increases the coverage of models of fundamental neurobiology, cognitive neuroscience, and neural network approaches to language. (Midwest).