Rational Therapeutics for Infants and Children

Rational Therapeutics for Infants and Children

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2000-04-07

Total Pages: 135

ISBN-13: 0309183642

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The Institute of Medicine's (IOM's) Roundtable on Research and Development of Drugs, Biologics, and Medical Devices evolved from the Forum on Drug Development, which was established in 1986. Sponsor representatives and IOM determined the importance of maintaining a neutral setting for discussions regarding long-term and politically sensitive issues justified the need to revise and enhance past efforts. The new Roundtable is intended to be a mechanism by which a broad group of experts from the public* and private sectors can be convened to conduct a dialogue and exchange information related to the development of drugs, biologics, and medical devices. Members have expertise in clinical medicine, pediatrics, clinical pharmacology, health policy, health insurance, industrial management, and product development; and they represent interests that address all facets of public policy issues. From time to time, the Roundtable requests that a workshop be conducted for the purpose of exploring a specific topic in detail and obtaining the views of additional experts. The first workshop for the Roundtable was held on April 14 and 15, 1998, and was entitled Assuring Data Quality and Validity in Clinical Trials for Regulatory Decision Making. The summary on that workshop is available from IOM. This workshop summary covers the second workshop, which was held on May 24 and 25, 1999, and which was aimed at facilitating the development and proper use of drugs, biologics, and medical devices for infants and children. It explores the scientific underpinnings and clinical needs, as well as the regulatory, legal, and ethical issues, raised by this area of research and development.


Comparative Anatomy and Histology

Comparative Anatomy and Histology

Author: Piper M. Treuting

Publisher: Academic Press

Published: 2012

Total Pages: 475

ISBN-13: 0123813611

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1. Introduction -- 2. Phenotyping -- 3. Necropsy and histology -- 4. Mammary Gland -- 5. Skeletal System -- 6. Nose, sinus, pharynx and larynx -- 7. Oral cavity and teeth -- 8. Salivary glands -- 9. Respiratory -- 10. Cardiovascular -- 11. Upper GI -- 12. Lower GI -- 13. Liver and gallbladder -- 14. Pancreas -- 15. Endocrine System -- 16. Urinary System -- 17. Female Reproductive System -- 18. Male Reproductive System -- 19. Hematopoietic and Lymphoid Tissues -- 20. Nervous System -- 21. Special senses, eye -- 22. Special senses, ear -- 23. Skin and adnexa -- Index.


Introduction to Biomedical Engineering

Introduction to Biomedical Engineering

Author: John Enderle

Publisher: Elsevier

Published: 2005-05-20

Total Pages: 1141

ISBN-13: 0080473148

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Under the direction of John Enderle, Susan Blanchard and Joe Bronzino, leaders in the field have contributed chapters on the most relevant subjects for biomedical engineering students. These chapters coincide with courses offered in all biomedical engineering programs so that it can be used at different levels for a variety of courses of this evolving field. Introduction to Biomedical Engineering, Second Edition provides a historical perspective of the major developments in the biomedical field. Also contained within are the fundamental principles underlying biomedical engineering design, analysis, and modeling procedures. The numerous examples, drill problems and exercises are used to reinforce concepts and develop problem-solving skills making this book an invaluable tool for all biomedical students and engineers. New to this edition: Computational Biology, Medical Imaging, Genomics and Bioinformatics.* 60% update from first edition to reflect the developing field of biomedical engineering* New chapters on Computational Biology, Medical Imaging, Genomics, and Bioinformatics* Companion site: http://intro-bme-book.bme.uconn.edu/* MATLAB and SIMULINK software used throughout to model and simulate dynamic systems* Numerous self-study homework problems and thorough cross-referencing for easy use


Introduction to the Anatomy and Physiology of Children

Introduction to the Anatomy and Physiology of Children

Author: Janet MacGregor

Publisher: Routledge

Published: 2008-04-18

Total Pages: 270

ISBN-13: 1134064721

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Fully updated, this new edition provides an introduction to normal, healthy physical development for all professionals who specialise in working with children. The author, an experienced nurse teacher, guides the reader through the key changes in body systems and functions from embryo to birth through childhood and adolescence. Chapter 1 sets the scene for physical needs in child development, such as the need to be warm and safe. Chapters 2 to 9 cover the body systems: skeletal; nervous; cardiovascular; respiratory; renal; digestive; reproductive; and immune. The embryology and physiological function at birth is explored in each chapter before the text moves on through the many changes over the next decade to puberty and the arrival at adult functioning. A new final chapter provides a holistic account of children’s development, body and mind. Each chapter is illustrated with line drawings and tables, and ends with scenarios which illustrate how knowledge supports good practice in a real-life situation, and a quiz to consolidate learning. Concise and clearly written, this introductory text will be essential reading for all those working with children and families in the health and social care sector, enabling them to ensure children enjoy a safe and healthy childhood in line with Every Child Matters and new national service framework directives.


Respiratory Care Anatomy and Physiology

Respiratory Care Anatomy and Physiology

Author: Will Beachey, PhD, RRT, FAARC

Publisher: Elsevier Health Sciences

Published: 2012-10-22

Total Pages: 483

ISBN-13: 0323078664

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Perfect for both practicing therapists and students in respiratory therapy and associated professions, this well-organized text offers the most clinically relevant and up-to-date information on respiratory applied anatomy and physiology. Content spans the areas of basic anatomy and physiology of the pulmonary, cardiovascular, and renal systems, and details the physiological principles underlying common therapeutic, diagnostic, and monitoring therapies and procedures. Using a clear and easy-to-understand format, this text helps you take a more clinical perspective and learn to think more critically about the subject matter. Open-ended concept questions require reasoned responses based on thorough comprehension of the text, fostering critical thinking and discussion. Clinical Focus boxes throughout the text place key subject matter in a clinical context to connect theory with practice. Chapter outlines, chapter objectives, key terms, and a bulleted chapter summary highlight important concepts and make content more accessible. Appendixes contain helpful tables and definitions of terms and symbols. NEW! Chapter on the physiological basis for treating sleep-disordered breathing clarifies the physiological mechanisms of sleep-disordered breathing and the various techniques required to treat this type of disorder. NEW! Reorganization of content places the section on the renal system before the section on integrated responses in exercise and aging to create a more logical flow of content. NEW! More Clinical Focus scenarios and concept questions provide additional opportunities to build upon content previously learned and to apply new information in the text.


Evidence-Based Medicine and the Changing Nature of Health Care

Evidence-Based Medicine and the Changing Nature of Health Care

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2008-09-06

Total Pages: 202

ISBN-13: 0309113695

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Drawing on the work of the Roundtable on Evidence-Based Medicine, the 2007 IOM Annual Meeting assessed some of the rapidly occurring changes in health care related to new diagnostic and treatment tools, emerging genetic insights, the developments in information technology, and healthcare costs, and discussed the need for a stronger focus on evidence to ensure that the promise of scientific discovery and technological innovation is efficiently captured to provide the right care for the right patient at the right time. As new discoveries continue to expand the universe of medical interventions, treatments, and methods of care, the need for a more systematic approach to evidence development and application becomes increasingly critical. Without better information about the effectiveness of different treatment options, the resulting uncertainty can lead to the delivery of services that may be unnecessary, unproven, or even harmful. Improving the evidence-base for medicine holds great potential to increase the quality and efficiency of medical care. The Annual Meeting, held on October 8, 2007, brought together many of the nation's leading authorities on various aspects of the issues - both challenges and opportunities - to present their perspectives and engage in discussion with the IOM membership.


Finding What Works in Health Care

Finding What Works in Health Care

Author: Institute of Medicine

Publisher: National Academies Press

Published: 2011-07-20

Total Pages: 267

ISBN-13: 0309164257

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Healthcare decision makers in search of reliable information that compares health interventions increasingly turn to systematic reviews for the best summary of the evidence. Systematic reviews identify, select, assess, and synthesize the findings of similar but separate studies, and can help clarify what is known and not known about the potential benefits and harms of drugs, devices, and other healthcare services. Systematic reviews can be helpful for clinicians who want to integrate research findings into their daily practices, for patients to make well-informed choices about their own care, for professional medical societies and other organizations that develop clinical practice guidelines. Too often systematic reviews are of uncertain or poor quality. There are no universally accepted standards for developing systematic reviews leading to variability in how conflicts of interest and biases are handled, how evidence is appraised, and the overall scientific rigor of the process. In Finding What Works in Health Care the Institute of Medicine (IOM) recommends 21 standards for developing high-quality systematic reviews of comparative effectiveness research. The standards address the entire systematic review process from the initial steps of formulating the topic and building the review team to producing a detailed final report that synthesizes what the evidence shows and where knowledge gaps remain. Finding What Works in Health Care also proposes a framework for improving the quality of the science underpinning systematic reviews. This book will serve as a vital resource for both sponsors and producers of systematic reviews of comparative effectiveness research.


Gross Anatomy: The Big Picture, Second Edition, SMARTBOOKTM

Gross Anatomy: The Big Picture, Second Edition, SMARTBOOKTM

Author: David A. Morton

Publisher: McGraw Hill Professional

Published: 2011-06-14

Total Pages: 513

ISBN-13: 0071785345

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Get the BIG PICTURE of Gross Anatomy in the context of healthcare – and zero-in on what you really need to know to ace the course and board exams! Gross Anatomy: The Big Picture is the perfect bridge between review and textbooks. With an emphasis on what you truly need to know versus “what’s nice to know,” it features 450 full-color illustrations that give you a complete, yet concise, overview of essential anatomy. The book’s user-friendly presentation consists of text on the left-hand page and beautiful full-color illustrations on the right-hand page. In this way, you get a “big picture” of anatomy principles, delivered one concept at a time -– making them easier to understand and retain. Striking the perfect balance between illustrations and text, Gross Anatomy: The Big Picture features: High-yield review questions and answers at the end of each chapter Numerous summary tables and figures that encapsulate important information 450 labeled and explained full-color illustrations A final exam featuring 100 Q&As Important clinically-relevant concepts called to your attention by convenient icons Bullets and numbering that break complex concepts down to easy-to-remember points