Health Risks of Radon and Other Internally Deposited Alpha-Emitters

Health Risks of Radon and Other Internally Deposited Alpha-Emitters

Author: National Research Council

Publisher: National Academies Press

Published: 1988-02-01

Total Pages: 623

ISBN-13: 0309037891

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This book describes hazards from radon progeny and other alpha-emitters that humans may inhale or ingest from their environment. In their analysis, the authors summarize in one document clinical and epidemiological evidence, the results of animal studies, research on alpha-particle damage at the cellular level, metabolic pathways for internal alpha-emitters, dosimetry and microdosimetry of radionuclides deposited in specific tissues, and the chemical toxicity of some low-specific-activity alpha-emitters. Techniques for estimating the risks to humans posed by radon and other internally deposited alpha-emitters are offered, along with a discussion of formulas, models, methods, and the level of uncertainty inherent in the risk estimates.


Targeted Radionuclide Therapy

Targeted Radionuclide Therapy

Author: Tod W. Speer

Publisher: Lippincott Williams & Wilkins

Published: 2012-03-28

Total Pages: 564

ISBN-13: 1451153260

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Radioimmunotherapy, also known as systemic targeted radiation therapy, uses antibodies, antibody fragments, or compounds as carriers to guide radiation to the targets. It is a topic rapidly increasing in importance and success in treatment of cancer patients. This book represents a comprehensive amalgamation of the radiation physics, chemistry, radiobiology, tumor models, and clinical data for targeted radionuclide therapy. It outlines the current challenges and provides a glimpse at future directions. With significant advances in cell biology and molecular engineering, many targeting constructs are now available that will safely deliver these highly cytotoxic radionuclides in a targeted fashion. A companion website includes the full text and an image bank.


Nuclear Oncology

Nuclear Oncology

Author: H. William Strauss

Publisher: Springer Science & Business Media

Published: 2012-11-27

Total Pages: 873

ISBN-13: 0387488944

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This book provides the reader with a comprehensive understanding of both the basic principles and the clinical applications of nuclear oncology imaging techniques. The authors have assembled a distinguished group of leaders in the field who provide valuable insight on the subject. The book also includes major chapters on the cancer patient and the pathophysiology of abnormal tissue, the evaluation of co-existing disease, and the diagnosis and therapy of specific tumors using functional imaging studies. Each chapter is heavily illustrated to assist the reader in understanding the clinical role of nuclear oncology in cancer disease therapy and management.


Age-Related Factors in Radionuclide Metabolism and Dosimetry

Age-Related Factors in Radionuclide Metabolism and Dosimetry

Author: G.B. Gerber

Publisher: Springer Science & Business Media

Published: 1987-07-31

Total Pages: 438

ISBN-13: 9780898389531

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Proceedings of a Workshop Held in Angers, France, November 26-28, 1986, Sponsored by the Commission of the European Communities Directorate General for Science, Research and Development


Handbook of Radiopharmaceuticals

Handbook of Radiopharmaceuticals

Author: Michael J. Welch

Publisher: John Wiley & Sons

Published: 2003-01-17

Total Pages: 872

ISBN-13: 9780471495604

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A comprehensive, authoritative and up-to-date reference for the newcomer to radiopharmaceuticals and those already in the field. Radiopharmaceuticals are used to detect and characterise disease processes, or normal biological function, in living cells, animals or humans. Used as tracer molecules, they map the distribution, uptake and metabolism of the molecule in clinical studies, basic research or applied research. The area of radiopharmaceuticals is expanding rapidly. The number of PET centers in the world is increasing at 20% per year, and many drug companies are utilising PET and other forms of radiopharmaceutical imaging to evaluate products. * Readers will find coverage on a number of important topics such as radionuclide production, PET and drug development, and regulations * Explains how to use radiopharmaceuticals for the diagnosis and therapy of cancer and other diseases * The editors and a majority of the contributors are from the United States


Uranium · Plutonium Transplutonic Elements

Uranium · Plutonium Transplutonic Elements

Author: Harold C. Hodge

Publisher: Springer Science & Business Media

Published: 2013-06-29

Total Pages: 1037

ISBN-13: 3642655513

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More than a year ago the three editors sat down at a table and worked out a set of six chapter headings which they believed might serve, in turn, for each of the three sections of this handbook. (The reader will note a similarity in order of presentation and in emphasis.) However, as our editorial plans progressed it became apparent that for each element and for the element group, there were one or two special topics appropiate for that section alone. Accordingly, in the section on uranium the common pattern holds for Chaps. 1 through 6 which include: an introduction (Chap. 1), a discussion of the physical and chemical properties (Chap. 2), experimental data on animals (Chap. 3), ex perimental data on man (Chap. 4), the rationale and development of air con centration limits to control industrial worker exposure (Chap. 5), and the prac tical problems of applying such limits in the uranium industry (Chap. 6). Chap. 7 entitled "Uranium Mining Hazards" is the subject category which is special for uranium; the chapter brings up to date the account of an important occupational hazard which was first noted by GEORGIUS AGRICOLA (1490-1555).


The Toxicity of Plutonium, Americium and Curium

The Toxicity of Plutonium, Americium and Curium

Author: J. C. Nenot

Publisher: Elsevier

Published: 2013-10-22

Total Pages: 238

ISBN-13: 148318210X

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The Toxicity of Plutonium, Americium and Curium provides a biological basis for an assessment of the radiological health problems resulting from human exposure to americium, curium, and plutonium. This book discusses the method of injection of the chelating agent DTPA for removing soluble forms of americium, curium, and plutonium. Organized into 10 chapters, this book begins with an overview of the biological effects in man that are attributed to exposure to actinides. This text then examines the uses of americium and curium in transmission scanning studies in tissues, in smoke detectors, and in neutron sources. Other chapters consider the metabolism or effects of plutonium in humans that can be employed to predict the potential consequences of human exposure. This book discusses as well routes of entry of radioactive materials into the body by inhalation, by ingestion, through cuts, or by absorption through the intact skin. The final chapter deals with the assessment of the radiological health problems resulting from the use of mixed oxide fuels of uranium and plutonium in light water reactors. This book is a valuable resource for scientists.