Death on Hemodialysis: Preventable or Inevitable? presents the transactions of the Brooklyn meeting, held in April 1993, including an analysis by Scribner and Schreiner and an introduction by Edmund Bourke. Authors include the heads of dialysis registries for Japan, Europe, and the United States, as well as protagonists of dialyser reuse and short dialysis times. Enthusiasts championed the determination of adequacy of dialysis by formulae or by clinical assessment. All chapters are direct and forceful. The reader will be able to judge the data on what are key controversies in planning dialysis protocols and schedules.
Glomerulonephritis is one of the commonest causes of end-stage renal failure worldwide. Although there have been considerable advances in the management of renal failure by dialysis and transplantation, there has been relatively little progress in its prevention. This volume sets out to review current practice in the treatment of glomerulonephritis, which is aimed both at controlling the clinical manifestations, e.g. nephrotic syndrome, and at preventing the progression to renal failure. The term glomerulonephritis covers a wide range of conditions with different immunological, histological and clinical features. This volume therefore starts with reviews of the immunology and pathology of different types of glomerulonephritis. This is followed by detailed consideration of the treatment of the commoner primary and secondary forms of the disease. There are separate chapters on special circumstances, such as glomerulonephritis in pregnancy or following renal transplantation. In each chapter, attempts are made to review the evidence for the effectiveness of treatment, based on controlled trials, immunopathological principles and the authors' considerable experience. Although some aspects of the treatment of glomerulonephritis can be found in the standard texts on renal disease, this volume provides an up-to-date, thoroughly referenced, and practical guide to management. As such, it should be of value to nephrologists and general physicians, including those in training, and to postgraduate students of nephrology.
After a decade or longer, approximately one-third of individuals with either type 1 or type 2 diabetes commence a downhill course in which decreasing renal function and failing vision define a Renal-Retinal Syndrome, dominating all aspects of life and presaging early death. Only a generation ago, survival after onset of end-stage renal disease (ESRD) in diabetes was limited because rehabilitation was preempted by blindness, limb amputation, stroke, and heart disease. By 1998, however, team management has improved the outlook, with preserved sight and return to work and home responsibilities, usually for a decade or longer, following kidney transplantation and laser photocoagulation. Recognition of the critical requirement for blood pressure regulation and metabolic control are central themes in management. In this unique book, the accomplishments of ophthalmologists, nephrologists, diabetologists, transplant surgeons, and basic scientists are blended into a strategic approach that may be readily applied by all those caring for diabetic patients. Each of twenty-one presentations suitable for primary care physicians, as well as for subspecialists concerned with macrovascular and microvascular complications of diabetes, is placed in perspective by an introductory editorial analysis. Promising near-term innovative therapies, including insertion of genetically engineered beta cells or polymer-coated islets of Langerhans, interdiction of kinins that promote retinal angiogenesis, and prevention of synthesis of advanced glycosylated endproducts (AGEs), are presented in detail. While comprehensive care of diabetic patients reflects multiple incremental advances that in sum afford major benefit, this text envisions further remarkable changes likely to suppress and possibly entirely prevent the Diabetic Renal-Retinal Syndrome.
Renal Failure, Diagnosis & Treatment is a practical book that provides a comprehensive description of the evaluation of renal insufficiency. It teaches the physician how to recognise the tell-tale signs of the diseases that cause kidney failure and how to confirm their presence in an efficient manner. Major teaching points are reinforced by the presentation of 20 problem cases for the reader's diagnosis. The book also details the general management of the patient with renal failure and the treatment of various causative diseases.
As the dialysis population grows, the number of survivors in the second and even third decade of dialysis also increase. These long term survivors face not only the universal complications of dialysis such as anemia and hyparathyroidism but also the consequences of these complications such as the long term cardiovascular problems. They are also subjected to many years of accumulation of "uremic metabolites" resulting in conditions unique to this group of patients, the best example being dialysis amyloid. This book not only describes the causes of morbidity and mortality during the second decade of dialysis but also how these complications can be prevented or minimised. "As you make your bed so you must lie upon it". Survival and quality of life in the second decade and beyond dialysis cannot be divorced from events in the first decade. The longest survival is currently in those patients who have dialysed long hours with tight control of fluid status. Modern dialysis practice and its impact on survival - CAPD, short hour hemodialysis, biocompatible membranes are all discussed in this book.
Completely revised edition of a global resource first published in 1978 and previously revised in 1989. Sixty-three contributions are arranged in sections on the pathophysiology of the uremic syndrome--principles and biophysics of dialysis; technology of dialysis and associated methods; quantification and prescription; complications; pharmacological considerations; special clinical situations; organ system and metabolic complications; and organization and results of chronic dialysis. The aim is to give understanding of the complexities of modern dialysis apparatus so that practitioners can make the best use of the technology--and so that fledgling nephrologists can avoid the temptation to by-pass the theory and the nuances. Annotation copyright by Book News, Inc., Portland, OR
More than half a million people worldwide are now sustained by renal replacement therapy, mainly hemodialysis at a cost exceeding USD 30 billion per year. Each case of ESRD that is delayed or prevented saves funds that may be applied to other aspects of health care. Edited by an internationally renowned nephrologist, Prognosis for Kidney Disorders provides a timely summary of exciting work in progress directed toward renoprotection and of ultimate interdiction of ESRD. Suitable for researchers and clinicians, Dr. Morrell Michael Avram has collected and commented on promising initiatives likely to enter everyday practice in the immediate future. Suitable for renal trainees, experienced kidney doctors, nurses, nutritionists and cardiologists.
The volumes in this series are, published annually on the occasion of the International Conference on Dialysis organized by the Renal Research Institute, New York, in collaboration with the ISN, ISPD, NKF and RPA. This year's meeting emphasized differences in opinion regarding dialysis guidelines, measurement of dialysis dose and the value of observational research. Besides, this volume includes papers on problems inherent in the management of a dialysis center; diabetes and dialysis; new information on topics such as dialysate composition; the role of body composition in dialysis outcome; problems associated with excess or deficiency of vitamin C; application of nanotechnology, or the role of periodontal disease as a cause of problems in dialysis patients. Last but not least, a molecular approach to infection in chronic kidney disease is presented, using detection of bacterial DNA in patients with sepsis. Covering a broad spectrum of topics, this publication is thus a most helpful reference tool for both clinicians and basic investigators involved in hemodialysis.
This book is an evidence-based review of the practical challenges of dealing with patients receiving dialysis. The first section covers technical and procedural considerations such as choosing the hemodialysis membrane and choosing the best dialysis option. The second section covers clinical considerations such as infection and the treatment of specific renal disease complications. The book includes numerous illustrations and tables and drug charts for dialysis patients. This edition's current outcomes chapter has been expanded to include patient depression and improving quality of care. New chapters cover dialysis in the ICU, valvular heart disease, and pre-emptive renal transplantation.
