De-Extinction and the Genomics Revolution

De-Extinction and the Genomics Revolution

Author: Amy Lynn Fletcher

Publisher: Springer Nature

Published: 2019-09-10

Total Pages: 88

ISBN-13: 3030257894

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This book considers the cultural history and politics of de-extinction, an approach to wildlife conservation that seeks to use advanced biotechnologies for genetic rescue, crisis interventions, and even species resurrections. It demonstrates how the genomic revolution creates new possibilities for human transformation of nature and accelerates the arrival of the era of life-on demand. Fletcher combines a summative overview of the modern progress in biology and biotechnology that has brought us to this moment and evaluates the relationship between de-extinction and provocative contemporary ideas such as rewilding, eco-modernism, and the Anthropocene. Overall, the book contends that de-extinction, as reported in the public sphere, shifts between the demands of science and spectacle and draws upon our ongoing fascination with lost worlds, Frankenstein’s monster, woolly mammoths, and dinosaurs.


How to Clone a Mammoth

How to Clone a Mammoth

Author: Beth Shapiro

Publisher: Princeton University Press

Published: 2020-09-08

Total Pages: 240

ISBN-13: 0691209561

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An insider's view on bringing extinct species back to life Could extinct species, like mammoths and passenger pigeons, be brought back to life? In How to Clone a Mammoth, Beth Shapiro, an evolutionary biologist and pioneer in ancient DNA research, addresses this intriguing question by walking readers through the astonishing and controversial process of de-extinction. From deciding which species should be restored to anticipating how revived populations might be overseen in the wild, Shapiro vividly explores the extraordinary cutting-edge science that is being used to resurrect the past. Considering de-extinction's practical benefits and ethical challenges, Shapiro argues that the overarching goal should be the revitalization and stabilization of contemporary ecosystems. Looking at the very real and compelling science behind an idea once seen as science fiction, How to Clone a Mammoth demonstrates how de-extinction will redefine conservation's future.


Conservation Genetics in the Age of Genomics

Conservation Genetics in the Age of Genomics

Author: George Amato

Publisher: Columbia University Press

Published: 2009-08-07

Total Pages: 504

ISBN-13: 0231502311

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Genome sequencing enables scientists to study genes over time and to test the genetic variability of any form of life, from bacteria to mammals. Thanks to advances in molecular genetics, scientists can now determine an animal's degree of inbreeding or compare genetic variation of a captive species to wild or natural populations. Mapping an organism's genetic makeup recasts such terms as biodiversity and species and enables the conservation of rare or threatened species, populations, and genes. By introducing a new paradigm for studying and preserving life at a variety of levels, genomics offers solutions to previously intractable problems in understanding the biology of complex organisms and creates new tools for preserving the patterns and processes of life on this planet. Featuring a number of high-profile researchers, this volume introduces the use of molecular genetics in conservation biology and provides a historical perspective on the opportunities and challenges presented by new technologies. It discusses zoo-, museum-, and herbarium-based biological collections, which have expanded over the past decade, and covers the promises and problems of genomic and reproductive technology. The collection concludes with the philosophical and legal issues of conservation genetics and their potential effects on public policy.


Regenesis

Regenesis

Author: George M Church

Publisher: Basic Books

Published: 2014-04-08

Total Pages: 305

ISBN-13: 0465038654

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A Harvard biologist and master inventor explores how new biotechnologies will enable us to bring species back from the dead, unlock vast supplies of renewable energy, and extend human life. In Regenesis, George Church and science writer Ed Regis explore the possibilities of the emerging field of synthetic biology. Synthetic biology, in which living organisms are selectively altered by modifying substantial portions of their genomes, allows for the creation of entirely new species of organisms. These technologies-far from the out-of-control nightmare depicted in science fiction-have the power to improve human and animal health, increase our intelligence, enhance our memory, and even extend our life span. A breathtaking look at the potential of this world-changing technology, Regenesis is nothing less than a guide to the future of life.


Altered Inheritance

Altered Inheritance

Author: Françoise Baylis

Publisher: Harvard University Press

Published: 2019-09-17

Total Pages: 305

ISBN-13: 0674976711

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A leading bioethicist offers critical insights into the scientific, ethical, and political implications of human genome editing. Designer babies, once found only in science fiction, have become a reality. We are entering a new era of human evolution with the advent of a technology called CRISPR, which allows scientists to modify our genes. Although CRISPR shows great promise for therapeutic use, it raises thorny ethical, legal, political, and societal concerns because it can be used to make permanent changes to future generations. What if changes intended for the good turn out to have unforeseen negative effects? What if the divide between the haves and have-nots widens as a result? Who decides whether we genetically modify human beings and, if so, how? Françoise Baylis insists that we must all have a role in determining our future as a species. The scientists who develop and use genome-editing tools should not be the only ones making decisions about future uses of the technology. Such decisions must be the fruit of a broad societal consensus. Baylis argues that it is in our collective interest to assess and steer the development and implementation of biomedical technologies. Members of the public with different interests and diverse perspectives must be among the decision makers; only in this way can we ensure that societal concerns are taken into account and that responsible decisions are made. We must be engaged and informed, think critically, and raise our voices as we create our future together. Sharp, rousing, timely, and thought-provoking, Altered Inheritance is essential reading. The future of humanity is in our hands.


What Is Extinction?

What Is Extinction?

Author: Joshua Schuster

Publisher: Fordham Univ Press

Published: 2023-02-21

Total Pages: 243

ISBN-13: 1531501664

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Life on Earth is facing a mass extinction event of our own making. Human activity is changing the biology and the meaning of extinction. What Is Extinction? examines several key moments that have come to define the terms of extinction over the past two centuries, exploring instances of animal and human finitude and the cultural forms used to document and interpret these events. Offering a critical theory for the critically endangered, Joshua Schuster proposes that different discourses of limits and lastness appear in specific extinction events over time as a response to changing attitudes toward species frailty. Understanding these extinction events also involves examining what happens when the conceptual and cultural forms used to account for species finitude are pressed to their limits as well. Schuster provides close readings of several case studies of extinction that bring together environmental humanities and multispecies methods with media-specific analyses at the terminus of life. What Is Extinction? delves into the development of last animal photography, the anthropological and psychoanalytic fascination with human origins and ends, the invention of new literary genres of last fictions, the rise of new extreme biopolitics in the Third Reich that attempted to change the meaning of extinction, and the current pursuit of de-extinction technologies. Schuster offers timely interpretations of how definitions and visions of extinction have changed in the past and continue to change in the present.


Resurrection Science

Resurrection Science

Author: M. R. O'Connor

Publisher: Macmillan + ORM

Published: 2015-09-15

Total Pages: 276

ISBN-13: 1466879327

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**A Library Journal Best Book of 2015 ** **A Christian Science Monitor Top Ten Book of September** In a world dominated by people and rapid climate change, species large and small are increasingly vulnerable to extinction. In Resurrection Science, journalist M. R. O'Connor explores the extreme measures scientists are taking to try and save them, from captive breeding and genetic management to de-extinction. Paradoxically, the more we intervene to save species, the less wild they often become. In stories of sixteenth-century galleon excavations, panther-tracking in Florida swamps, ancient African rainforests, Neanderthal tool-making, and cryogenic DNA banks, O'Connor investigates the philosophical questions of an age in which we "play god" with earth's biodiversity. Each chapter in this beautifully written book focuses on a unique species--from the charismatic northern white rhinoceros to the infamous passenger pigeon--and the people entwined in the animals' fates. Incorporating natural history and evolutionary biology with conversations with eminent ethicists, O'Connor's narrative goes to the heart of the human enterprise: What should we preserve of wilderness as we hurtle toward a future in which technology is present in nearly every aspect of our lives? How can we co-exist with species when our existence and their survival appear to be pitted against one another?


The Epochal Event

The Epochal Event

Author: Zoltán Boldizsár Simon

Publisher: Springer Nature

Published: 2020-07-23

Total Pages: 153

ISBN-13: 303047805X

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This book is a unique attempt to capture the growing societal experience of living in an age unlike anything the world has ever seen. Fueled by the perception of acquiring unprecedented powers through technologies that entangle the human and the natural worlds, human beings have become agents of a new kind of transformative event. The ongoing sixth mass extinction of species, the prospect of a technological singularity, and the potential crossing of planetary boundaries are expected to trigger transformations on a planetary scale that we deem catastrophic and try to avoid. In making sense of these prospects, Simon’s book sketches the rise of a new epochal thinking, introduces the epochal event as an emerging category of a renewed historical thought, and makes the case for the necessity of bringing together the work of the human and the natural sciences in developing knowledge of a more-than-human world.


Evolution by Gene Duplication

Evolution by Gene Duplication

Author: Susumu Ohno

Publisher: Springer Science & Business Media

Published: 2013-12-11

Total Pages: 171

ISBN-13: 364286659X

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It is said that "necessity is the mother of invention". To be sure, wheels and pulleys were invented out of necessity by the tenacious minds of upright citi zens. Looking at the history of mankind, however, one has to add that "Ieisure is the mother of cultural improvement". Man's creative genius flourished only when his mind, freed from the worry of daily toils, was permitted to entertain apparently useless thoughts. In the same manner, one might say with regard to evolution that "natural selection mere(y tnodifted, while redundanry created". Natural selection has been extremely effective in policing alleHe mutations which arise in already existing gene loci. Because of natural selection, organisms have been able to adapt to changing environments, and by adaptive radiation many new species were created from a common ancestral form. Y et, being an effective policeman, natural selection is extremely conservative by nature. Had evolution been entirely dependent upon natural selection, from a bacterium only numerous forms of bacteria would have emerged. The creation of metazoans, vertebrates and finally mammals from unicellular organisms would have been quite impos sible, for such big leaps in evolution required the creation of new gene loci with previously nonexistent functions. Only the cistron which became redun dant was able to escape from the relentless pressure of natural selection, and by escaping, it accumulated formerly forbidden mutations to emerge as a new gene locus.


The Last of Its Kind

The Last of Its Kind

Author: Gísli Pálsson

Publisher: Princeton University Press

Published: 2024-02-06

Total Pages: 320

ISBN-13: 0691230986

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How an iconic bird’s final days exposed the reality of human-caused extinction The great auk is one of the most tragic and documented examples of extinction. A flightless bird that bred primarily on the remote islands of the North Atlantic, the last of its kind were killed in Iceland in 1844. Gísli Pálsson draws on firsthand accounts from the Icelanders who hunted the last great auks to bring to life a bygone age of Victorian scientific exploration while offering vital insights into the extinction of species. Pálsson vividly recounts how British ornithologists John Wolley and Alfred Newton set out for Iceland to collect specimens only to discover that the great auks were already gone. At the time, the Victorian world viewed extinction as an impossibility or trivialized it as a natural phenomenon. Pálsson chronicles how Wolley and Newton documented the fate of the last birds through interviews with the men who killed them, and how the naturalists’ Icelandic journey opened their eyes to the disappearance of species as a subject of scientific concern—and as something that could be caused by humans. Blending a richly evocative narrative with rare, unpublished material as well as insights from ornithology, anthropology, and Pálsson’s own North Atlantic travels, The Last of Its Kind reveals how the saga of the great auk opens a window onto the human causes of mass extinction.