This book is a 2015 update and annotation of independent research into the environmental aspects of polio causation, with its primary article originally published in Townsend Letter for Doctors and Patients, June 2000. The author has been active in environmental politics in New York with the NoSpray Coalition, since 2000. He is a member of the Toastmasters group, GreenSpeakers.
The Immunization Safety Review Committee was established by the Institute of Medicine (IOM) to evaluate the evidence on possible causal associations between immunizations and certain adverse outcomes, and to then present conclusions and recommendations. The committee's mandate also includes assessing the broader societal significance of these immunization safety issues. While all the committee members share the view that immunization is generally beneficial, none of them has a vested interest in the specific immunization safety issues that come before the group. The committee reviews three immunization safety review topics each year, addressing each one at a time. In this fifth report in a series, the committee examines the hypothesis that exposure to polio vaccine contaminated with simian virus 40 (SV40), a virus that causes inapparent infection in some monkeys, can cause certain types of cancer.
Vaccines have saved more lives than any other single medical advance. Yet today only four companies make vaccines, and there is a growing crisis in vaccine availability. Why has this happened? This remarkable book recounts for the first time a devastating episode in 1955 at Cutter Laboratories in Berkeley, California, thathas led many pharmaceutical companies to abandon vaccine manufacture. Drawing on interviews with public health officials, pharmaceutical company executives, attorneys, Cutter employees, and victims of the vaccine, as well as on previously unavailable archives, Dr. Paul Offit offers a full account of the Cutter disaster. He describes the nation's relief when the polio vaccine was developed by Jonas Salk in 1955, the production of the vaccine at industrial facilities such as the one operated by Cutter, and the tragedy that occurred when 200,000 people were inadvertently injected with live virulent polio virus: 70,000 became ill, 200 were permanently paralyzed, and 10 died. Dr. Offit also explores how, as a consequence of the tragedy, one jury's verdict set in motion events that eventually suppressed the production of vaccines already licensed and deterred the development of new vaccines that hold the promise of preventing other fatal diseases.
A fascinating account of the world's most famous disease-polio- told as you have never heard it before. Epidemics of paralysis began to rage in the early 1900s, seemingly out of nowhere. Doctors, parents, and health officials were at a loss to explain why this formerly unheard of disease began paralyzing so many children-usually starting in their legs, sometimes moving up through their abdomen and arms. For an unfortunate few, it could paralyze the muscles that allowed them to breathe. Why did this disease start to become such a horrible problem during the late 1800s? Why did it affect children more often than adults? Why was it originally called teething paralysis by mothers and their doctors? Why were animals so often paralyzed during the early epidemics when it was later discovered most animals could not become infected? The Moth in the Iron Lung is a fascinating biography of this horrible paralytic disease, where it came from, and why it disappeared in the 1950s. If you've never explored the polio story beyond the tales of crippled children and iron lungs, this book will be sure to surprise.
The story of an infamous poison that left toxic bodies and decimated wildlife in its wake is also a cautionary tale about how corporations stoke the flames of science denialism for profit. The chemical compound DDT first earned fame during World War II by wiping out insects that caused disease and boosting Allied forces to victory. Americans granted it a hero’s homecoming, spraying it on everything from crops and livestock to cupboards and curtains. Then, in 1972, it was banned in the US. But decades after that, a cry arose to demand its return. This is the sweeping narrative of generations of Americans who struggled to make sense of the notorious chemical’s risks and benefits. Historian Elena Conis follows DDT from postwar farms, factories, and suburban enclaves to the floors of Congress and tony social clubs, where industry barons met with Madison Avenue brain trusts to figure out how to sell the idea that a little poison in our food and bodies was nothing to worry about. In an age of spreading misinformation on issues including pesticides, vaccines, and climate change, Conis shows that we need new ways of communicating about science—as a constantly evolving discipline, not an immutable collection of facts—before it’s too late.
In 1988, the World Health Organization launched a twelve-year campaign to wipe out polio. Thirty years and several billion dollars over budget later, the campaign grinds on, vaccinating millions of children and hoping that each new year might see an end to the disease. But success remains elusive, against a surprisingly resilient virus, an unexpectedly weak vaccine and the vagaries of global politics, meeting with indifference from governments and populations alike. How did an innocuous campaign to rid the world of a crippling disease become a hostage of geopolitics? Why do parents refuse to vaccinate their children against polio? And why have poorly paid door-to-door healthworkers been assassinated? Thomas Abraham reports on the ground in search of answers.
"A timely, fair-minded and crisply written account."—New York Times Book Review Vaccine juxtaposes the stories of brilliant scientists with the industry's struggle to produce safe, effective, and profitable vaccines. It focuses on the role of military and medical authority in the introduction of vaccines and looks at why some parents have resisted this authority. Political and social intrigue have often accompanied vaccination—from the divisive introduction of smallpox inoculation in colonial Boston to the 9,000 lawsuits recently filed by parents convinced that vaccines caused their children's autism. With narrative grace and investigative journalism, Arthur Allen reveals a history illuminated by hope and shrouded by controversy, and he sheds new light on changing notions of health, risk, and the common good.
From the 1930s to the 1950s, in response to the rising epidemic of paralytic poliomyelitis (polio), Texas researchers led a wave of discoveries in virology, rehabilitative therapies, and the modern intensive care unit that transformed the field nationally. The disease threatened the lives of children and adults in the United States, especially in the South, arousing the same kind of fear more recently associated with AIDS and other dread diseases. Houston and Harris County, Texas, had the second-highest rate of infection in the nation, and the rest of the Texas Gulf Coast was particularly hard-hit by this debilitating illness. At the time, little was known, but eventually the medical responses to polio changed the medical landscape forever. Polio also had a sweeping cultural and societal effect. It engendered fearful responses from parents trying to keep children safe from its ravages and an all-out public information blitz aimed at helping a frightened population protect itself. The disease exacted a very real toll on the families, friends, healthcare resources, and social fabric of those who contracted the disease and endured its acute, convalescent, and rehabilitation phases. In The Polio Years in Texas, Heather Green Wooten draws on extensive archival research as well as interviews conducted over a five-year period with Texas polio survivors and their families. This is a detailed and intensely human account of not only the epidemics that swept Texas during the polio years, but also of the continuing aftermath of the disease for those who are still living with its effects. Public health and medical professionals, historians, and interested general readers will derive deep and lasting benefits from reading The Polio Years in Texas.
Some investigators have hypothesized that estrogens and other hormonally active agents found in the environment might be involved in breast cancer increases and sperm count declines in humans as well as deformities and reproductive problems seen in wildlife. This book looks in detail at the science behind the ominous prospect of "estrogen mimics" threatening health and well-being, from the level of ecosystems and populations to individual people and animals. The committee identifies research needs and offers specific recommendations to decision-makers. This authoritative volume: Critically evaluates the literature on hormonally active agents in the environment and identifies known and suspected toxicologic mechanisms and effects of fish, wildlife, and humans. Examines whether and how exposure to hormonally active agents occursâ€"in diet, in pharmaceuticals, from industrial releases into the environmentâ€"and why the debate centers on estrogens. Identifies significant uncertainties, limitations of knowledge, and weaknesses in the scientific literature. The book presents a wealth of information and investigates a wide range of examples across the spectrum of life that might be related to these agents.
Dirt and Disease is a social, cultural, and medical history of the polio epidemic in the United States. Naomi Rogers focuses on the early years from 1900 to 1920, and continues the story to the present. She explores how scientists, physicians, patients, and their families explained the appearance and spread of polio and how they tried to cope with it. Rogers frames this study of polio within a set of larger questions about health and disease in twentieth-century American culture.