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Author: Marilyn Chernoff
Publisher: Trafford Publishing
Published: 2005
Total Pages: 219
ISBN-13: 1412064228
DOWNLOAD EBOOKEver wondered why some people are ill in ways doctors seem unable to diagnose? Dr. Marilyn Chernoff's research makes it clear toxic contamination may be what is affecting us.
Author: Steven G. Gilbert
Publisher: CRC Press
Published: 2004-02-18
Total Pages: 279
ISBN-13: 0203461738
DOWNLOAD EBOOKEveryday, we come into contact with many relatively harmless substances that could, at certain concentrations, be toxic. This applies not only to obvious candidates such as asbestos, lead, and gasoline, but also to compounds such as caffeine and headache tablets. While the field of toxicology has numerous texts devoted to aspects of biology, chemis
Author: Ali S. Faqi
Publisher: Academic Press
Published: 2016-11-03
Total Pages: 988
ISBN-13: 0128036214
DOWNLOAD EBOOKA Comprehensive Guide to Toxicology in Nonclinical Drug Development, Second Edition, is a valuable reference designed to provide a complete understanding of all aspects of nonclinical toxicology in the development of small molecules and biologics. This updated edition has been reorganized and expanded to include important topics such as stem cells in nonclinical toxicology, inhalation and dermal toxicology, pitfalls in drug development, biomarkers in toxicology, and more. Thoroughly updated to reflect the latest scientific advances and with increased coverage of international regulatory guidelines, this second edition is an essential and practical resource for all toxicologists involved in nonclinical testing in industry, academic, and regulatory settings. - Provides unique content that is not always covered together in one comprehensive resource, including chapters on stem cells, abuse liability, biomarkers, inhalation toxicology, biostatistics, and more - Updated with the latest international guidelines for nonclinical toxicology in both small and large molecules - Incorporates practical examples in order to illustrate day-to-day activities and the expectations associated with working in nonclinical toxicology
Author: National Research Council
Publisher: National Academies Press
Published: 1991-02-01
Total Pages: 224
ISBN-13: 0309044375
DOWNLOAD EBOOKThe National Human Monitoring Program (NHMP) identifies concentrations of specific chemicals in human tissues, including toxicologic testing and risk assessment determinations. This volume evaluates the current activities of the NHMP; identifies important scientific, technical, and programmatic issues; and makes recommendations regarding the design of the program and use of its products.
Author: Solomon Kadis
Publisher: Elsevier
Published: 2013-10-22
Total Pages: 419
ISBN-13: 1483259684
DOWNLOAD EBOOKMicrobial Toxins: A Comprehensive Treatise, Volume VIII, Fungal Toxins is devoted to topics related to algal and fungal toxins and includes critically reviewed articles from different experts in related fields. The text is divided into three sections. Section A covers coumarins — its isolation, identification, biological action, natural occurrence, and uses. Section B deals with the epizootiology, clinical characteristics, and pathological findings of Stachybotryotoxicosis. Section C talks about phytopathogenic and helminthosporium toxins, toxic peptides found in Amanita species as well as other mushroom toxins, compounds accumulating in plants after an infection, and ergot. The book is recommended for microbiologists and toxicologists, especially those who would like to know more about the toxins produced by algae and fungi and their effects.
Author: Waldemar M. Dabrowski
Publisher: CRC Press
Published: 2004-11-15
Total Pages: 376
ISBN-13: 0203502353
DOWNLOAD EBOOKWhile systems such as GMP and HACCP assure a high standard of food quality, foodborne poisonings still pose a serious hazard to the consumer's health. The lack of knowledge among some producers and consumers regarding the risks and benefits related to food makes it imperative to provide updated information in order to improve food safety. To
Author: Steven Mercurio
Publisher: Jones & Bartlett Learning
Published: 2016-08-30
Total Pages: 952
ISBN-13: 1284127613
DOWNLOAD EBOOKUnderstanding Toxicology is a comprehensive study of toxicants and their impact on all levels of biology--from cell, to complex organism, to ecosystem. Unlike other texts of its kind, this text is uniquely structured by biological system, making it easy for readers to understand the impact of toxins on each system. Common mechanisms are explored in the cellular and complex organ system chapters to approach a systems biology perspective that is more applicable to modern computational toxicology risk assessment. Understanding Toxicology begins with three research questions that challenge the reader to discover what information is needed to solve controversies at the level of the cell, the complex organism, and the ecosystem. The book continues with a cellular, complex organism, and ecosystem analysis of toxicology principles including risk assessment. The cellular section follows common mechanisms from the outside to the inside of cells and individual organelles. A forensic approach analyzes complex organisms from outside to inside. The ecosystem section starts with a dispersion approach to determine environmental concentration and addresses toxicants in divisions similar to how the EPA determines impacts. Key Features • Uses lively, engaging examples making the text fun and easy to read and understand • Allows the reader to approach the subject from a research perspective as well as a public policy perspective • Covers biological toxicants including venoms, poisons, as well as microbial and fungal toxins, and plant toxins • Thoroughly covers all organisms including fish, plants, and microbes • Includes outlines and review questions in each chapter
Author: Philip Rosenberg
Publisher: Elsevier
Published: 2013-10-02
Total Pages: 1169
ISBN-13: 1483153533
DOWNLOAD EBOOKToxins: Animal, Plant and Microbial is a collection of materials from the proceedings of the Fifth International Symposium on Animal, Plant, and Microbial toxins, held in Costa Rica in August 1976. The book deals with research done on reptiles, arthropods, marine, fresh water, amphibia, plants, bacteria, and multispecies focusing on topics such as biology, anatomy, immunology, bio-chemistry, physiology, and pharmacology. The paper starts with the feeding methods and diet for snakes that will be used for venom collection. Another paper describes the venom apparatus and amount of venom yields of the snake Hydrophiidae. The book also describes the ultrastructure of the skin of the soapfish Grammistes sexlineatus, known to release an irritating substance when threatened or disturbed. One paper presents the effect of toxins derived from the scorpion venom on neuromuscular transmission, while another study describes anti-scorpion serum and antivenin with a corresponding table representing the correct serum dosage. The book then presents a method to use for quantitative separation and analysis of certain mycotoxins that can be present in foodstuffs. One paper also addresses the effects of mycotoxins on immunity levels, such as lowered resistance to diseases, interference with acquired immunity, and changes in antibody production. Chemists, students and professors in organic chemistry, and laboratory technicians whose work is related to pharmacology and toxicology will find this book relevant.
Author: John Whysner
Publisher: Columbia University Press
Published: 2020-06-02
Total Pages: 229
ISBN-13: 0231549504
DOWNLOAD EBOOKSince the dawn of the industrial age, we have unleashed a bewildering number of potentially harmful chemicals. But out of this vast array, how do we identify the actual threats? What does it take to prove that a certain chemical causes cancer? How do we translate academic knowledge of the toxic effects of particular substances into understanding real-world health consequences? The science that answers these questions is toxicology. In The Alchemy of Disease, John Whysner offers an accessible and compelling history of toxicology and its key findings. He details the experiments and discoveries that revealed the causal connections between chemical exposures and diseases. Balancing clear accounts of groundbreaking science with human drama and public-policy relevance, Whysner describes key moments in the development of toxicology and their thorny social and political implications. The book features discussions of toxicological problems past and present, including DDT, cigarettes and other carcinogens, lead poisoning, fossil fuels, chemical warfare, pharmaceuticals—including opioids—and the efficacy of animal testing. Offering valuable insight into the science and politics of crucial public-health concerns, The Alchemy of Disease shows that toxicology’s task—pinpointing the chemical cause of an illness—is as compelling as any detective story.
Author: A. Witczak
Publisher: CRC Press
Published: 2017-01-12
Total Pages: 509
ISBN-13: 1498748538
DOWNLOAD EBOOKPresents information, based on scientific evidence, on the contents of harmful compounds in food raw materials and products, such as grains, fruits and vegetables, mushrooms, seafood, milk and dairy products, meats, and various processed foods Shows the effects of environmental pollution and the conditions of harvesting and storage of the raw materials on food contamination Discusses the real food safety hazards to the consumers caused by toxins of microbial origin and chemical contamination Describes the beneficial role of processing to decrease the contents of harmful components in food products Presents the role of legislation, quality assurance systems, and available analytical techniques in assuring food safety
