Critical Care Management for Laboratory Mice and Rats

Critical Care Management for Laboratory Mice and Rats

Author: F. Claire Hankenson

Publisher: CRC Press

Published: 2013-10-03

Total Pages: 274

ISBN-13: 0849324998

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For critical care of laboratory rodents, there is a scarcity of sources for comprehensive, feasible, and response-oriented information on clinical interventions specific to spontaneous and induced models of disease. With the more complex cases that need critical care management, many treatment approaches to veterinary emergencies cannot be applied directly to the laboratory rodent. The first text of its kind devoted to the challenges of critical care management for laboratory rodents, Critical Care Management for Laboratory Mice and Rats provides a specialized resource for all veterinary, husbandry, technical, and research professionals who utilize rodent models for biomedical research. The book covers the varied approaches to laboratory rodent patient care, health assessments, characteristics of specific disease models, monitoring and scoring of disease parameters, and humane interventions. Giving primary consideration to preservation of animal health and welfare, the text also considers how best to balance welfare with the achievement of proposed scientific objectives. Organized into five chapters, this full-color book covers the following topics: General Approaches for Critical Care Critical Care Management for Laboratory Mice Critical Care Management for Laboratory Rats Special Considerations for Critical Care Management in Laboratory Rodents Resources and Additional Information The author provides treatment guidelines with the expectation that they will be applied with apt professional judgment, allowing for further modification of clinical recommendations for improved patient-based care and welfare for research animals.


Guide for the Care and Use of Laboratory Animals

Guide for the Care and Use of Laboratory Animals

Author: National Research Council

Publisher: National Academies Press

Published: 2011-01-27

Total Pages: 246

ISBN-13: 0309154006

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A respected resource for decades, the Guide for the Care and Use of Laboratory Animals has been updated by a committee of experts, taking into consideration input from the scientific and laboratory animal communities and the public at large. The Guide incorporates new scientific information on common laboratory animals, including aquatic species, and includes extensive references. It is organized around major components of animal use: Key concepts of animal care and use. The Guide sets the framework for the humane care and use of laboratory animals. Animal care and use program. The Guide discusses the concept of a broad Program of Animal Care and Use, including roles and responsibilities of the Institutional Official, Attending Veterinarian and the Institutional Animal Care and Use Committee. Animal environment, husbandry, and management. A chapter on this topic is now divided into sections on terrestrial and aquatic animals and provides recommendations for housing and environment, husbandry, behavioral and population management, and more. Veterinary care. The Guide discusses veterinary care and the responsibilities of the Attending Veterinarian. It includes recommendations on animal procurement and transportation, preventive medicine (including animal biosecurity), and clinical care and management. The Guide addresses distress and pain recognition and relief, and issues surrounding euthanasia. Physical plant. The Guide identifies design issues, providing construction guidelines for functional areas; considerations such as drainage, vibration and noise control, and environmental monitoring; and specialized facilities for animal housing and research needs. The Guide for the Care and Use of Laboratory Animals provides a framework for the judgments required in the management of animal facilities. This updated and expanded resource of proven value will be important to scientists and researchers, veterinarians, animal care personnel, facilities managers, institutional administrators, policy makers involved in research issues, and animal welfare advocates.


Nutrient Requirements of Laboratory Animals,

Nutrient Requirements of Laboratory Animals,

Author: National Research Council

Publisher: National Academies Press

Published: 1995-02-01

Total Pages: 188

ISBN-13: 0309051266

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In the years since the third edition of this indispensable reference was published, a great deal has been learned about the nutritional requirements of common laboratory species: rat, mouse, guinea pig, hamster, gerbil, and vole. The Fourth Revised Edition presents the current expert understanding of the lipid, carbohydrate, protein, mineral, vitamin, and other nutritional needs of these animals. The extensive use of tables provides easy access to a wealth of comprehensive data and resource information. The volume also provides an expanded background discussion of general dietary considerations. In addition to a more user-friendly organization, new features in this edition include: A significantly expanded section on dietary requirements for rats, reporting substantial new findings. A new section on nutrients that are not required but that may produce beneficial results. New information on growth and reproductive performance among the most commonly used strains of rats and mice and on several hamster species. An expanded discussion of diet formulation and preparationâ€"including sample diets of both purified and natural ingredients. New information on mineral deficiency and toxicity, including warning signs. This authoritative resource will be important to researchers, laboratory technicians, and manufacturers of laboratory animal feed.


Handbook of Laboratory Animal Anesthesia and Pain Management

Handbook of Laboratory Animal Anesthesia and Pain Management

Author: Cholawat Pacharinsak

Publisher: CRC Press

Published: 2017-03-27

Total Pages: 198

ISBN-13: 1466585684

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Key features: Presents practical information in easily accessible ‘bullet point’ format Covers anesthetic machine and related equipment, anesthetic management and monitoring, anesthesia and analgesia pharmacology, euthanasia, and record keeping Written by well-recognized experts in the laboratory animal community Provides extensive references to direct the reader to sources for further study of alternative techniques and their procedures Concludes with a thorough chapter on Regulatory Management of Rodent Anesthesia which has global application Rodents are the most commonly used species in biomedical research. Individuals conducting rodent research are often responsible to ensure that all areas of anesthesia and analgesia are performed humanely. Anesthetic agent selection, anesthetic monitoring, and postoperative pain assessment and management are essential to the institutional animal care and use program and contribute significantly to the 3Rs by reducing pain and/or distress and refining various procedures. The Handbook of Laboratory Animal Anesthesia and Pain Management: Rodents is the first book to capture multiple advances in this important area that greatly impacts various experimental methodologies. Richly illustrated in full color, the book serves as a quick reference source for investigators, veterinarians, technicians, and other animal caretakers charged with the care and use of rodents in a research setting. The unique format of this book also makes it extremely valuable to IACUC members, institutional officials, and occupational health and safety professionals.


Exotic Animal Emergency and Critical Care Medicine

Exotic Animal Emergency and Critical Care Medicine

Author: Jennifer E. Graham

Publisher: John Wiley & Sons

Published: 2021-11-23

Total Pages: 996

ISBN-13: 1119149231

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Exotic Animal Emergency and Critical Care Medicine delivers the most relevant and current information required by general veterinary practitioners and veterinary specialists in treating emergent and critical exotic patients. Covering the management of common emergency presentations in exotic companion mammals, birds, reptiles, and amphibians, each section discusses triage and stabilization, diagnostics, nutrition and fluid therapy, analgesia, anesthesia, monitoring, CPR, and euthanasia. The book includes quick reference tables, species-specific drug formularies, and illustrations of exotic animal emergency procedures and techniques. The information contained within is based on an extensive review of the most current literature and the combined knowledge and expertise of international leaders in the field of exotic animal medicine and surgery. A one-stop resource like no other, Exotic Animal Emergency and Critical Care Medicine makes it easy to find the information needed to effectively treat urgent and life-threatening conditions in pet exotic animals. The book covers a wide range of species, encompassing: Exotic companion mammals, including ferrets, rabbits, guinea pigs, chinchillas, rats, mice, hamsters, gerbils, hedgehogs, and sugar gliders Birds, including psittacines, passerines, doves and pigeons, as well as backyard poultry and waterfowl Reptiles, including turtles and tortoises, snakes and lizards Amphibians Equally useful for general practitioners, specialists in emergency and critical care and exotic animal medicine, veterinary students, and trainees, Exotic Animal Emergency and Critical Care Medicine is an essential resource for the emergent and critical care of exotic animals.


Laboratory Animal

Laboratory Animal

Author: Lizabeth A Terril

Publisher: CRC-Press

Published: 2000-12-01

Total Pages: 167

ISBN-13: 9780849325601

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The Laboratory Animal Pocket Reference Series was created to assist anyone who works with laboratory animals, enabling him or her to provide the most humane and responsible care. These 14 volumes are compact and comb-bound to lay flat for use in the laboratory. The contents of each includes important biological features, husbandry, management, veterinary care, regulatory concerns, and commonly used and new procedures, as well as a section that includes an invaluable list of suppliers. Each book in the series can be purchased individually or as part of the set. The series includes the following titles: The Laboratory Cat The Laboratory Nonhuman Primate The Laboratory Hamster and Gerbil The Laboratory Small Ruminant The Laboratory Canine The Laboratory Xenopus The Laboratory Zebrafish The Laboratory Ferret The Laboratory Swine, Second Edition The Laboratory Rabbit, Second Edition The Laboratory Guinea Pig, Second Edition The Laboratory Mouse, Second Edition The Laboratory Rat, Second Edition Critical Care Management for Laboratory Mice and Rats


The Laboratory Rat, Second Edition

The Laboratory Rat, Second Edition

Author: Patrick Sharp

Publisher: CRC Press

Published: 2012-12-11

Total Pages: 403

ISBN-13: 1439829861

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Rats have long been recognized as a valuable biomedical research model, notably in the investigation of aging, toxicology, addiction, and common human diseases such as diabetes and hypertension. In many instances, individuals conducting such research studies are charged with important responsibilities, including animal facility management, animal husbandry, veterinary care, regulatory compliance, and various experimental methodologies. With the advent of genetic manipulations and biomedical research technological advances such as bioimaging, the versatility and usefulness of the rat as an animal model has soared. The Laboratory Rat, Second Edition captures the multiple advances in this important animal model’s husbandry, veterinary care, and experimental methodology. This edition features augmented, expanded, and novel information on biology, anesthesia, analgesia, and experimental techniques benefiting personnel working with rats—from the animal care staff to the researcher and everyone in between. The book is also extremely useful to institutional animal care and use program supporters and elements, including animal care and use committees, institutional officials, occupational health and safety professionals, veterinary technicians, and veterinarians.


Anesthesia and Analgesia in Laboratory Animals

Anesthesia and Analgesia in Laboratory Animals

Author: Melissa Dyson

Publisher: Academic Press

Published: 2023-05-17

Total Pages: 790

ISBN-13: 0128222204

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Anesthesia and Analgesia in Laboratory Animals focuses on the special anesthetic, analgesic and postoperative care requirements associated with experimental interventions. Fully revised and updated, this new edition provides the reader with agents, methods and techniques for anesthesia and analgesia that ensure humane, reproducible, and successful procedural outcomes. Sections cover ethical, regulatory and scientific considerations, principles of anesthesia and analgesia, anesthetic equipment and monitoring, periprocedural care, including dedicated chapters to the assessment and management of pain in laboratory species, and practical considerations by species, including relevant anatomy, physiology, and behavior of a broad range of lab animal species. This will be a complete reference for veterinarians involved in lab animal research as well as senior graduate, graduate students, post-docs and researchers who utilize animals in biomedical research. Provides researchers with the most comprehensive and up-to-date review of the use of anesthesia and analgesia in laboratory animals Includes complete coverage of agents' impact in research outcomes Thoroughly updated with new material on ferrets, birds, reptiles, amphibians, fish and cephalopods Covers hot topic areas such as pain research, ethical issues, legal issues and imaging studies


The Laboratory Mouse

The Laboratory Mouse

Author: Hans Hedrich

Publisher: Academic Press

Published: 2012-07-16

Total Pages: 869

ISBN-13: 0123820081

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"Mice have long been recognized as a valuable tool for investigating the genetic and physiological bases of human diseases such as diabetes, infectious disease, cancer, heart disease, and a wide array of neurological disorders. With the advent of transgenic and other genetic engineering technologies, the versatility and usefulness of the mouse as a model in biomedical research has soared. As a result, mouse colonies everywhere are expanding, and scientists who previously focused on other models are turning their attention to the mouse. Revised to reflect advances since the first edition, The Laboratory Mouse, Second Edition continues to be the most accessible reference on the biology and care of the laboratory mouse. This guide presents basic information and common procedures in detail to provide a quick reference source for investigators, technicians, and caretakers in the humane care and use of the mouse in the laboratory setting. Expanded, updated, and now in color, this new edition includes coverage of the biological features, husbandry, management, veterinary care, experimental methodology, and resources applying specifically to the mouse"--Provided by publisher.


Laboratory Animal Anaesthesia

Laboratory Animal Anaesthesia

Author: Paul Flecknell

Publisher: Academic Press

Published: 2009-04-09

Total Pages: 325

ISBN-13: 0080918999

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Laboratory Animal Anesthesia looks at recent significant developments in anesthetic practices in laboratory experiments involving animals. It also provides information about basic standards for proper use of anesthesia. In addition, it examines the equipment and different anesthetic agents that are used in performing an experiment on animals. The book also discusses the profound effects of anesthesia on the physiological aspect of the animals’ body systems, such as hypothermia and respiratory depression. The book addresses the proper management and care that should be provided for the animals that undergo anesthesia. Furthermore, it covers different anesthetic procedures that should be used on various kinds of small animals intended for laboratory experiments. The main goal of this book is to provide information about the different anesthetic agents used in experiments, and the proper standards to follow when using anesthetics on lab animals. • New edition provides new information on anesthesia and analgesia, and has an extensively revised and updated bibliography• Provides a balanced consideration of the needs of scientific research and the welfare of laboratory animals• Written by a veterinary anesthetist and scientist with over 30 years' experience in the field, and who is actively engaged in research in this area• Provides rapid, easily accessed information using tabulated summaries• Provides those with limited experience of anesthesia with the information they need to carry our procedures effectively, safely, and humanely• Provides sufficient depth for the more experienced anesthetist moving to this field