Controlled Release of Bioactive Materials
Controlled Release of Bioactive Materials

Author: Richard Baker

Publisher: Elsevier

Published: 2012-12-02

Total Pages: 488

ISBN-13: 0323148417

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Controlled Release of Bioactive Materials is a collection papers that deal with the study of controlled release applications in drugs and other pharmacological products and processes. The text covers topics such as the theory and practice of controlled drug delivery from bioerodible polymers, biodegradable drug delivery systems from aliphatic polyesters, and the applications of osmotic drug delivery. Also covered are topics such as the application of polymers for the sustained release of macromolecules, controlled transdermal delivery, and the use of hydrogel devices for the controlled release of steroid hormones. The book is recommended for pharmacologists and doctors who would like to know more about advancements in the field of controlled release applications and its uses in healthcare, especially in pharmacology.

Controlled Release
Controlled Release

Author: Liang-tseng Fan

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 242

ISBN-13: 3642745075

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The concept of controlled release has attracted increasing attention over the last two decades, with the applications of this technology proliferating in diverse fields in cluding medicine, agriculture and biotechnology. Research and developmental efforts related to controlled release are multiplying in both industry and academia. The reason for this phenomenal growth is obvious. The use of a variety of biologically active agents, such as drugs, fertilizers and pesticides, has become an integral part of modern society. Along with the use of these reagents has evolved an awareness that their uncontrolled application almost inevitably induces harmful effects on the health of humans and their surrounding environments. To eliminate or minimize these harmful effects necessitates the controlled release of these chemicals. Moreover, the controlled release of substances, not usually considered toxic or hazardous, e.g., some catalysts and nutrients, can enhance their effectiveness. The number and variety of controlled release systems, differing in their physical and chemical makeup, are increasing rapidly. Proliferation almost always demands correlation, generalization and unification; it requires both the development of underlying theories of their behavior and the mechanistic interpretation of their performance. This, in turn, requires a statistical and mathematical (quantitative) treatment of the scientific information and technical data pertaining to them. A quantitative treatment can also facilitate the formulation of procedures for computer-aided design of these systems through a priori prediction of their per formance for a variety of design parameters.

The Application of Bioactive Materials in Bone Repair
The Application of Bioactive Materials in Bone Repair

Author: Hu Yan

Publisher: Frontiers Media SA

Published: 2024-11-12

Total Pages: 203

ISBN-13: 2832556736

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Biological activity, in the field of materials, mainly refers to the properties that can induce special biological and chemical reactions at the interface between materials and biological tissues, forming chemical bonds between materials and biological tissues. A bioactive material is a biomaterial that is able to participate in a regenerative process at the molecular level and dictate molecular and cellular events in a preferred and predictable way. In the process of biomineralization, the ability of biological material to chemically bond with living bone is an important index of the biomaterial, and the biological activity of the material in vivo is reflected by the simulated body fluid-SBF ability of apatite formed on the surface of the material. In the field of bone repair, bioactive materials such as hydrogels, agglomerates, and magnetic nanoparticles are playing an increasingly important role. Compared with traditional bone repair materials, bioactive materials have many advantages, such as high biocompatibility, simulation of the extracellular environment, and easy engineering modification. In addition, as a delivery system, bioactive materials are modified and engineered to be minimally invasive, targeted, and sustainably released. The above characteristics have important application value in the field of bone repair.

Bioactive Polymeric Systems
Bioactive Polymeric Systems

Author: Charles G. Gebelein

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 698

ISBN-13: 1475704054

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The vast array of libraries in the world bear mute witness to the truth of the 3000-year-old observation of King Solomon who stated " ... of making many books there is no end, and much study is a weariness of the flesh." Yet books are an essential written record of our lives and the progress of science and humanity. Here is another book to add to this huge collection, but, hopefully, not just another collection of pages, but rather a book with a specific purpose to aid in alleviating the "weariness of the flesh" that could arise from much studying of other journals and books in order to obtain the basic information contained herein. This book is about polymeric materials and biological activity, as the title notes. Polymeric materials, in the broad view taken here, would include not only synthetic polymers (e.g., polyethylene, polyvinyl chloride, polyesters, polyamides, etc.), but also the natural macromolecules (e.g., proteins, nucleic acids, polysaccharides) which compose natural tissues in humans, animals and plants. In the broad sense used here, biological activity is any type of such action whether it be in medication, pest control, plant-growth regu lation, and so on. In short, this book attempts to consider, briefly, the use of any type of polymeric material system with essentially any kind of biological activity.

Degradation Rate of Bioresorbable Materials
Degradation Rate of Bioresorbable Materials

Author: F J Buchanan

Publisher: Elsevier

Published: 2008-09-26

Total Pages: 425

ISBN-13: 1845695038

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Bioresorbable materials are extensively used for a wide range of biomedical applications from drug delivery to fracture fixation, and may remain in the body for weeks, months or even years. Accurately predicting and evaluating the degradation rate of these materials is critical to their performance and the controlled release of bioactive agents. Degradation rate of bioresorbable materials provides a comprehensive review of the most important techniques in safely predicting and evaluating the degradation rate of polymer, ceramic and composite based biomaterials.Part one provides an introductory review of bioresorbable materials and the biological environment of the body. Chapters in Part two address degradation mechanisms of commonly used materials such as polymers and ceramics. This is followed by chapters on bioresorption test methods and modelling techniques in Part three. Part four discusses factors influencing bioresorbability such as sterilisation, porosity and host response. The final section reviews current clinical applications of bioresorbable materials.With its distinguished editor and multidisciplinary team of international contributors, Degradation rate of bioresorbable materials: prediction and evaluation provides a unique and valuable reference for biomaterials scientists, engineers and students as well as the medical community. - Comprehensively reviews the most pertinent techniques in safely predicting and evaluating the degradation rate of bioresorbable materials - Addresses degradation mechanisms of commonly used materials - Discusses factors influencing bioresorbability such as sterilisation and host response

Advanced Biomaterials in Biomedical Engineering and Drug Delivery Systems
Advanced Biomaterials in Biomedical Engineering and Drug Delivery Systems

Author: Naoya Ogata

Publisher: Springer Science & Business Media

Published: 2012-12-06

Total Pages: 395

ISBN-13: 4431658831

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First of all, I would like to share the great pleasure of the successful five-day symposium with every participant in the 5th Iketani Conference which was held in Kagoshima from April1S (Tuesday) to 22 (Saturday), 1995. Outstanding speakers enthusiastically presented their up-to-the-minute results. Relatively little time was allotted for each presentation to ensure asdnuch time· as possible for intensive discussions on the particular topics that had just been p~esented: I was delighted to see that the lectures were of high quality, and the discu,ssionswere lively, exciting, and productive in a congenial atmosphere. We also had 92 papers in the poster ·session, in which young (and relatively young) scientists made every effort to present the novel results of their research in advanced biomaterials and drug delivery systems (DDS). I believe some of the research is most promising and will become noteworthy in the twenty-first century. It was a privilege for me to deliver a lecture at the special session of the symposium. In my introductory remarks, I pointed out five key terms in multifaceted biomaterials research: materials design, concept or methodology, devices, properties demanded, and fundamentals. I am confident that innovative progress in device manufacturing for end-use, e.g., artificial organs, vascular grafts, and DDS, can be brought about only through properly designed advanced materials that exhibit the desired functionality at the interface with any living body.

Delivery and Controlled Release of Bioactives in Foods and Nutraceuticals
Delivery and Controlled Release of Bioactives in Foods and Nutraceuticals

Author: Nissim Garti

Publisher: Elsevier

Published: 2008-01-25

Total Pages: 497

ISBN-13: 184569421X

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Active ingredients in foods must remain fully functional for as long as necessary and be transported and discharged appropriately to have the desired nutritional effect. Delivery and controlled release systems are an essential way to achieve these aims. This important book reviews how to optimise these systems to maximise the health-promoting properties of food products.Opening chapters review factors affecting nutrient bioavailability and methods to test delivery system efficacy. Part two addresses materials used and specific techniques for delivery and release. The benefits and drawbacks of structured lipids, micro- and nano-emulsions, food-protein-derived materials, complexes and conjugates of biopolymers, and starch as an encapsulation material for delivery of functional food ingredients, are all considered. Part three discusses the delivery and controlled release of particular nutraceuticals such as antioxidants and vitamins, folic acid, probiotics, fish oils and proteins. Part four covers regulatory issues and future trends in bioactives and nutraceuticals.Edited by a leading expert in the field, Delivery and controlled release of bioactives in foods and nutraceuticals is a valuable reference for those working in the food industry and particularly those developing nutraceuticals. - Reviews techniques to optimise the delivery and release of bioactives in food - Discusses the factors that affect nutrient bioavailability and methods to test delivery system efficacy - Addresses materials used and specific techniques for delivery and release

Handbook of Encapsulation and Controlled Release
Handbook of Encapsulation and Controlled Release

Author: Munmaya Mishra

Publisher: CRC Press

Published: 2015-12-01

Total Pages: 1516

ISBN-13: 1482232340

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The field of encapsulation, especially microencapsulation, is a rapidly growing area of research and product development. The Handbook of Encapsulation and Controlled Release covers the entire field, presenting the fundamental processes involved and exploring how to use those processes for different applications in industry. Written at a level comp